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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for ModE

Z-value: 1.14

Transcription factors associated with ModE

Gene Symbol Gene ID Gene Info
modE
modE ModE transcriptional dual regulator

Activity profile of ModE motif

Sorted Z-values of ModE motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
napFDAGHBC-ccmABCDEFGH 8.15
napG
napF
napD
napC
ccmH
napA
ccmE
ccmD
ccmG
ccmF
ccmA
ccmC
ccmB
napH
napB
ferredoxin-type protein
ferredoxin-type protein
signal peptide-binding chaperone for NapA
periplasmic nitrate reductase, cytochrome c protein
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmH
large subunit of periplasmic nitrate reductase, molybdoprotein
membrane anchored periplasmic heme chaperone CcmE
ABC complex for formation and release of holoCcmE - membrane subunit CcmD
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmG
holocytochrome c synthetase - CcmF subunit
ABC complex for formation and release of holoCcmE - ATP binding subunit
ABC complex for formation and release of holoCcmE - membrane subunit CcmC
ABC complex for formation and release of holoCcmE - membrane subunit CcmB
ferredoxin-type protein
subunit of periplasmic nitrate reductase, cytochrome c550 protein
oppABCDF 7.81
oppA
oppC
oppB
oppD
oppF
peptide ABC transporter - periplasmic binding protein
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
moaABCDE 5.88
moaE
moaD
moaC
moaB
moaA
molybdopterin synthase large subunit
molybdopterin synthase small subunit
cyclic pyranopterin monophosphate synthase
MoaB protein
GTP 3',8'-cyclase
modABC 1.15
modA
modB
modC
molybdate ABC transporter - periplasmic binding protein
molybdate ABC transporter - membrane subunit
molybdate ABC transporter - ATP binding subunit

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0051223 heme transport(GO:0015886) protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) regulation of protein localization(GO:0032880) regulation of protein transport(GO:0051223) regulation of establishment of protein localization(GO:0070201)
2.6 7.8 GO:0035672 oligopeptide transport(GO:0006857) oligopeptide transmembrane transport(GO:0035672)
2.0 5.9 GO:0034214 protein hexamerization(GO:0034214) GTP metabolic process(GO:0046039) prosthetic group metabolic process(GO:0051189)
0.1 1.2 GO:0015698 inorganic anion transport(GO:0015698)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 9.0 GO:0098533 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0005048 signal sequence binding(GO:0005048)
2.6 7.8 GO:0015647 oligopeptide transporter activity(GO:0015198) peptidoglycan transporter activity(GO:0015647) oligopeptide transmembrane transporter activity(GO:0035673)
1.0 5.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.3 1.2 GO:0030151 molybdenum ion binding(GO:0030151)