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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MetR

Z-value: 0.35

Transcription factors associated with MetR

Gene Symbol Gene ID Gene Info
metR
metR MetR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
metR0.088.4e-01Click!

Activity profile of MetR motif

Sorted Z-values of MetR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
hmp 1.07
hmp
nitric oxide dioxygenase
metH 0.99
metH
cobalamin-dependent methionine synthase
metR 0.44
metR
MetR DNA-binding transcriptional dual regulator
metE 0.24
metE
cobalamin-independent homocysteine transmethylase

Network of associatons between targets according to the STRING database.

First level regulatory network of MetR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.4 1.1 GO:0046209 nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.1 GO:0051213 hydroperoxide reductase activity(GO:0032843) dioxygenase activity(GO:0051213)
0.0 0.4 GO:0016597 amino acid binding(GO:0016597)