ISMARA results: MetJ

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MetJ

Z-value: 0.86

Transcription factors associated with MetJ

Gene Symbol	Gene ID	Gene Info
metJ RegulonDB EcoCyc	metJ	MetJ transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
metJ		-0.61	1.1e-01	Click!

Activity profile of MetJ motif

Sorted Z-values of MetJ motif

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Promoter	Log-likelihood	Gene	Gene Info
metA Show fit	4.79	metA RegulonDB EcoCyc Show fit	homoserine O-succinyltransferase
metR Show fit	4.56	metR RegulonDB EcoCyc Show fit	MetR DNA-binding transcriptional dual regulator
metF Show fit	2.90	metF RegulonDB EcoCyc Show fit	5,10-methylenetetrahydrofolate reductase
metC Show fit	1.97	metC RegulonDB EcoCyc Show fit	cystathionine-β-lyase / L-cysteine desulfhydrase
metE Show fit	0.97	metE RegulonDB EcoCyc Show fit	cobalamin-independent homocysteine transmethylase

Showing 1 to 5 of 5 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of MetJ

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.6	GO:0006355	regulation of transcription, DNA-templated(GO:0006355) regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141)
1.0	3.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.4	2.0	GO:0044273	sulfur compound catabolic process(GO:0044273)

Showing 1 to 3 of 3 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0005576	extracellular region(GO:0005576)

Showing 1 to 1 of 1 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.8	GO:0016748	succinyltransferase activity(GO:0016748)
0.3	4.6	GO:0016597	amino acid binding(GO:0016597)
0.4	2.9	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.4	2.0	GO:0080146	L-cysteine desulfhydrase activity(GO:0080146)
0.2	1.0	GO:0008172	S-methyltransferase activity(GO:0008172)

Showing 1 to 5 of 5 entries

Results for MetJ

Z-value: 0.86

Transcription factors associated with MetJ

Activity-expression correlation:

Activity profile of MetJ motif

Sorted Z-values of MetJ motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MetJ

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: