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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MetJ

Z-value: 0.86

Transcription factors associated with MetJ

Gene Symbol Gene ID Gene Info
metJ MetJ transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
metJ-0.611.1e-01Click!

Activity profile of MetJ motif

Sorted Z-values of MetJ motif

Promoter Log-likelihood Transcript Gene Gene Info
metA 4.79 homoserine O-succinyltransferase
metR 4.56 MetR DNA-binding transcriptional dual regulator
metF 2.90 5,10-methylenetetrahydrofolate reductase
metC 1.97 cystathionine-β-lyase / L-cysteine desulfhydrase
metE 0.97 cobalamin-independent homocysteine transmethylase

Network of associatons between targets according to the STRING database.

First level regulatory network of MetJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.4 2.0 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 4.6 GO:0006355 regulation of transcription, DNA-templated(GO:0006355) regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 2.0 GO:0080146 L-cysteine desulfhydrase activity(GO:0080146)
0.4 2.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.3 4.6 GO:0016597 amino acid binding(GO:0016597)
0.2 1.0 GO:0008172 S-methyltransferase activity(GO:0008172)