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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for LsrR

Z-value: 0.85

Transcription factors associated with LsrR

Gene Symbol Gene ID Gene Info
lsrR LsrR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lsrR0.961.1e-04Click!

Activity profile of LsrR motif

Sorted Z-values of LsrR motif

Promoter Log-likelihood Transcript Gene Gene Info
lsrACDBFG-tam 5.99 AI-2 ABC transporter - ATP binding subunit
Autoinducer-2 ABC transporter - membrane subunit
autoinducer-2 ABC transporter - periplasmic binding protein
Autoinducer-2 ABC transporter - membrane subunit
phospho-AI-2 isomerase
3-hydroxy-2,4-pentadione 5-phosphate thiolase
trans-aconitate 2-methyltransferase
lsrRK 4.01 autoinducer-2 kinase
LsrR DNA-binding transcriptional repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of LsrR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0009372 quorum sensing(GO:0009372)
0.1 6.0 GO:0055114 oxidation-reduction process(GO:0055114)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 6.0 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 GO:0015145 monosaccharide transmembrane transporter activity(GO:0015145)
0.2 4.0 GO:0000987 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)