ISMARA results: LsrR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for LsrR

Z-value: 0.85

Transcription factors associated with LsrR

Gene Symbol	Gene ID	Gene Info
lsrR RegulonDB EcoCyc	lsrR	LsrR DNA-binding transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
lsrR		0.96	1.1e-04	Click!

Activity profile of LsrR motif

Sorted Z-values of LsrR motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
lsrACDBFG-tam Show fit	5.99		lsrA RegulonDB EcoCyc Show fit lsrC RegulonDB EcoCyc Show fit lsrB RegulonDB EcoCyc Show fit lsrD RegulonDB EcoCyc Show fit lsrG RegulonDB EcoCyc Show fit lsrF RegulonDB EcoCyc Show fit tam RegulonDB EcoCyc Show fit	AI-2 ABC transporter - ATP binding subunit Autoinducer-2 ABC transporter - membrane subunit autoinducer-2 ABC transporter - periplasmic binding protein Autoinducer-2 ABC transporter - membrane subunit phospho-AI-2 isomerase 3-hydroxy-2,4-pentadione 5-phosphate thiolase trans-aconitate 2-methyltransferase
lsrRK Show fit	4.01		lsrK RegulonDB EcoCyc Show fit lsrR RegulonDB EcoCyc Show fit	autoinducer-2 kinase LsrR DNA-binding transcriptional repressor

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Network of associatons between targets according to the STRING database.

First level regulatory network of LsrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.0	GO:0055114	oxidation-reduction process(GO:0055114)
1.3	4.0	GO:0009372	quorum sensing(GO:0009372)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.0	GO:0016021	integral component of membrane(GO:0016021)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.0	GO:0015145	monosaccharide transmembrane transporter activity(GO:0015145)
0.2	4.0	GO:0000987	bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)

Showing 1 to 2 of 2 entries

Results for LsrR

Z-value: 0.85

Transcription factors associated with LsrR

Activity-expression correlation:

Activity profile of LsrR motif

Sorted Z-values of LsrR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of LsrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: