ISMARA results: GlcC

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for GlcC

Z-value: 1.12

Transcription factors associated with GlcC

Gene Symbol	Gene ID	Gene Info
glcC RegulonDB EcoCyc	glcC	GlcC transcriptional dual regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
glcC		0.93	9.5e-04	Click!

Activity profile of GlcC motif

Sorted Z-values of GlcC motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
glcC Show fit	14.50		glcC RegulonDB EcoCyc Show fit	GlcC transcriptional dual regulator
glcDEFGBA Show fit	3.62		glcD RegulonDB EcoCyc Show fit glcE RegulonDB EcoCyc Show fit glcF RegulonDB EcoCyc Show fit glcG RegulonDB EcoCyc Show fit glcA RegulonDB EcoCyc Show fit glcB RegulonDB EcoCyc Show fit	glycolate oxidase, predicted FAD-linked subunit glycolate oxidase, predicted FAD-binding subunit glycolate oxidase, predicted iron-sulfur subunit conserved protein glycolate / lactate:H⁺ symporter malate synthase G

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Network of associatons between targets according to the STRING database.

First level regulatory network of GlcC

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.5	GO:2001141	regulation of transcription, DNA-templated(GO:0006355) regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141)
0.7	3.6	GO:0034308	primary alcohol metabolic process(GO:0034308) glyoxylate metabolic process(GO:0046487)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.6	GO:0005887	integral component of plasma membrane(GO:0005887)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.5	GO:0003677	DNA binding(GO:0003677)
0.9	3.6	GO:0046912	glycolate transmembrane transporter activity(GO:0043879) transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)

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Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.6	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates

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Results for GlcC

Z-value: 1.12

Transcription factors associated with GlcC

Activity-expression correlation:

Activity profile of GlcC motif

Sorted Z-values of GlcC motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GlcC

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: