ISMARA results: GadE-RcsB

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for GadE-RcsB

Z-value: 0.81

Transcription factors associated with GadE-RcsB

Gene Symbol	Gene ID	Gene Info
gadE RegulonDB EcoCyc	gadE	GadE DNA-binding transcriptional activator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
gadE		-0.68	6.2e-02	Click!

Activity profile of GadE-RcsB motif

Sorted Z-values of GadE-RcsB motif

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Promoter	Log-likelihood	Gene	Gene Info
gadAX Show fit	3.46	gadX RegulonDB EcoCyc Show fit gadA RegulonDB EcoCyc Show fit	GadX DNA-binding transcriptional dual regulator glutamate decarboxylase A subunit
aslB Show fit	2.06	aslB RegulonDB EcoCyc Show fit	predicted anaerobic sulfatase maturation enzyme
yhiM Show fit	1.26	yhiM RegulonDB EcoCyc Show fit	inner membrane protein with a role in acid resistance
adiC Show fit	0.86	adiC RegulonDB EcoCyc Show fit	AdiC arginine:agmatine antiporter
slp-dctR Show fit	0.79	slp RegulonDB EcoCyc Show fit dctR RegulonDB EcoCyc Show fit	starvation lipoprotein predicted DNA-binding transcriptional regulator
cadBA Show fit	0.02	cadA RegulonDB EcoCyc Show fit cadB RegulonDB EcoCyc Show fit	lysine decarboxylase 1 lysine:cadaverine antiporter

Showing 1 to 6 of 6 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of GadE-RcsB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:0051454	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1	2.1	GO:0051604	protein maturation(GO:0051604)
0.3	1.3	GO:0071229	cellular response to acid chemical(GO:0071229)
0.3	0.8	GO:0043471	regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471)

Showing 1 to 4 of 4 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.6	GO:0016020	membrane(GO:0016020)
0.0	0.8	GO:0019867	outer membrane(GO:0019867)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.5	GO:0001140	transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140)
0.2	0.9	GO:0015181	arginine transmembrane transporter activity(GO:0015181)

Showing 1 to 2 of 2 entries

Results for GadE-RcsB

Z-value: 0.81

Transcription factors associated with GadE-RcsB

Activity-expression correlation:

Activity profile of GadE-RcsB motif

Sorted Z-values of GadE-RcsB motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GadE-RcsB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: