ISMARA results: FliZ

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for FliZ

Z-value: 1.16

Transcription factors associated with FliZ

Gene Symbol	Gene ID	Gene Info
fliZ RegulonDB EcoCyc	fliZ	FliZ DNA-binding transcriptional regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
fliZ		0.69	5.7e-02	Click!
fliA		0.69	5.7e-02	Click!

Activity profile of FliZ motif

Sorted Z-values of FliZ motif

Top targets:

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Promoter	Log-likelihood	Gene	Gene Info
csgDEFG Show fit	10.46	csgG RegulonDB EcoCyc Show fit csgF RegulonDB EcoCyc Show fit csgE RegulonDB EcoCyc Show fit csgD RegulonDB EcoCyc Show fit	curli secretion channel curli assembly component curli transport specificity factor CsgD DNA-binding transcriptional dual regulator
mlrA Show fit	6.51	mlrA RegulonDB EcoCyc Show fit	MlrA DNA binding transcriptional activator
gadBC Show fit	3.96	gadB RegulonDB EcoCyc Show fit gadC RegulonDB EcoCyc Show fit	glutamate decarboxylase B subunit glutamic acid:4-aminobutyrate antiporter
csgBAC Show fit	3.89	csgC RegulonDB EcoCyc Show fit csgB RegulonDB EcoCyc Show fit csgA RegulonDB EcoCyc Show fit	inhibitor of CsgA amyloid formation curlin, minor subunit curlin, major subunit
osmY Show fit	3.20	osmY RegulonDB EcoCyc Show fit	periplasmic chaperone, osmotically induced
pdeR Show fit	0.68	pdeR RegulonDB EcoCyc Show fit	cyclic di-GMP phosphodiesterase

Showing 1 to 6 of 6 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of FliZ

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.6	14.4	GO:0022610	biological adhesion(GO:0022610)
1.0	4.0	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.4	3.2	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.7	GO:0043086	negative regulation of catalytic activity(GO:0043086)

Showing 1 to 4 of 4 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	10.5	GO:0031246	intrinsic component of periplasmic side of cell outer membrane(GO:0031246)
0.0	4.0	GO:0005887	integral component of plasma membrane(GO:0005887)
0.6	3.9	GO:0042995	cell projection(GO:0042995)
0.0	0.7	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	10.5	GO:0001159	bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	6.5	GO:0003700	transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3	4.0	GO:0015297	antiporter activity(GO:0015297)
0.1	0.7	GO:0071111	cyclic-guanylate-specific phosphodiesterase activity(GO:0071111)

Showing 1 to 4 of 4 entries

Results for FliZ

Z-value: 1.16

Transcription factors associated with FliZ

Activity-expression correlation:

Activity profile of FliZ motif

Sorted Z-values of FliZ motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FliZ

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: