ISMARA results: FhlA

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for FhlA

Z-value: 0.95

Transcription factors associated with FhlA

Gene Symbol	Gene ID	Gene Info
fhlA RegulonDB EcoCyc	fhlA	FhlA transcriptional activator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
fhlA		0.98	2.5e-05	Click!

Activity profile of FhlA motif

Sorted Z-values of FhlA motif

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Promoter	Log-likelihood	Gene	Gene Info
fdhF Show fit	7.15	fdhF RegulonDB EcoCyc Show fit	formate dehydrogenase H
hypABCDE Show fit	6.00	hypE RegulonDB EcoCyc Show fit hypD RegulonDB EcoCyc Show fit hypA RegulonDB EcoCyc Show fit hypC RegulonDB EcoCyc Show fit hypB RegulonDB EcoCyc Show fit	hydrogenase maturation protein, carbamoyl dehydratase HypD, scaffold protein for assembly of the Fe-(CN)₂CO cofactor accessory protein for nickel incorporation into hydrogenase 3 HypC, protein involved in hydrogenase 3 maturation accessory protein for nickel incorporation into hydrogenase isoenzymes
hypABCDE-fhlA Show fit	5.94	fhlA RegulonDB EcoCyc Show fit hypE RegulonDB EcoCyc Show fit hypD RegulonDB EcoCyc Show fit hypA RegulonDB EcoCyc Show fit hypC RegulonDB EcoCyc Show fit hypB RegulonDB EcoCyc Show fit	FhlA transcriptional activator hydrogenase maturation protein, carbamoyl dehydratase HypD, scaffold protein for assembly of the Fe-(CN)₂CO cofactor accessory protein for nickel incorporation into hydrogenase 3 HypC, protein involved in hydrogenase 3 maturation accessory protein for nickel incorporation into hydrogenase isoenzymes
hydN-hypF Show fit	0.94	hypF RegulonDB EcoCyc Show fit hydN RegulonDB EcoCyc Show fit	hydrogenase maturation protein, carbamoyltransferase putative electron transport protein HydN

Showing 1 to 4 of 4 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of FhlA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.0	11.9	GO:0018249	protein dehydration(GO:0018249) peptidyl-S-carbamoyl-L-cysteine dehydration(GO:0046892)
1.8	7.2	GO:0015942	formate metabolic process(GO:0015942)

Showing 1 to 2 of 2 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	11.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	7.2	GO:0005829	cytosol(GO:0005829)
0.0	0.9	GO:0005737	cytoplasm(GO:0005737)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.0	11.9	GO:0070025	carbon monoxide binding(GO:0070025)
1.2	7.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.2	0.9	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)

Showing 1 to 3 of 3 entries

Results for FhlA

Z-value: 0.95

Transcription factors associated with FhlA

Activity-expression correlation:

Activity profile of FhlA motif

Sorted Z-values of FhlA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FhlA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: