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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for DcuR

Z-value: 0.65

Transcription factors associated with DcuR

Gene Symbol Gene ID Gene Info
dcuR
dcuR DcuR transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dcuR0.403.3e-01Click!

Activity profile of DcuR motif

Sorted Z-values of DcuR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
dcuB-fumB 2.71
fumB
dcuB
fumarase B
dicarboxylate transporter DcuB
frdABCD 0.58
frdA
frdB
frdC
frdD
fumarate reductase flavoprotein
fumarate reductase iron-sulfur protein
fumarate reductase membrane protein
fumarate reductase membrane protein
dpiBA 0.56
dpiB
dpiA
DpiB sensory histidine kinase
DpiA transcriptional dual regulator
dctA 0.36
dctA
C4 dicarboxylate / orotate:H+ symporter

Network of associatons between targets according to the STRING database.

First level regulatory network of DcuR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.2 0.6 GO:0071310 cellular response to organic substance(GO:0071310)
0.1 0.6 GO:0006113 fermentation(GO:0006113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0045274 respiratory chain complex II(GO:0045273) plasma membrane respiratory chain complex II(GO:0045274)
0.0 3.6 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0005469 succinate:fumarate antiporter activity(GO:0005469)
0.4 0.4 GO:0015138 dicarboxylic acid transmembrane transporter activity(GO:0005310) fumarate transmembrane transporter activity(GO:0015138) succinate transmembrane transporter activity(GO:0015141) C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.2 0.6 GO:0000104 succinate dehydrogenase activity(GO:0000104) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.6 GO:0000156 phosphorelay response regulator activity(GO:0000156)