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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for CsgD

Z-value: 0.98

Transcription factors associated with CsgD

Gene Symbol Gene ID Gene Info
csgD CsgD DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
csgD0.944.4e-04Click!

Activity profile of CsgD motif

Sorted Z-values of CsgD motif

Promoter Log-likelihood Transcript Gene Gene Info
nlpA 6.64 lipoprotein-28
yccT 4.31 conserved protein
iraP 2.53 anti-adaptor protein for σS stabilization
csgDEFG 2.48 curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator
csgBAC 2.46 inhibitor of CsgA amyloid formation
curlin, minor subunit
curlin, major subunit
dgcC 2.13 diguanylate cyclase
fliE 0.86 flagellar basal-body protein FliE
flgMN 0.60 flagellar biosynthesis protein FlgN
anti-sigma factor for FliA (σ28)
fliFGHIJK 0.20 flagellum-specific ATP synthase FliI
flagellar biosynthesis protein FliH
flagellar hook-length control protein FliK
flagellar biosynthesis protein FliJ
flagellar motor switch protein FliG
flagellar M-ring protein FliF; basal-body MS(membrane and supramembrane)-ring and collar protein

Network of associatons between targets according to the STRING database.

First level regulatory network of CsgD

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.1 GO:0000101 sulfur amino acid transport(GO:0000101)
0.8 2.5 GO:0009895 negative regulation of catabolic process(GO:0009895) regulation of protein catabolic process(GO:0042176) negative regulation of protein catabolic process(GO:0042177)
0.5 4.9 GO:0022610 biological adhesion(GO:0022610)
0.1 0.6 GO:0030162 regulation of proteolysis(GO:0030162)
0.0 0.2 GO:0044780 bacterial-type flagellum assembly(GO:0044780) bacterial-type flagellum organization(GO:0044781)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0042995 cell projection(GO:0042995)
0.3 2.5 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)
0.0 6.6 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0043856 anti-sigma factor antagonist activity(GO:0043856)
0.5 2.1 GO:0052621 diguanylate cyclase activity(GO:0052621)
0.1 2.5 GO:0001159 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)