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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for Cbl

Z-value: 0.75

Transcription factors associated with Cbl

Gene Symbol Gene ID Gene Info
cbl Cbl DNA-binding transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cbl1.004.0e-09Click!

Activity profile of Cbl motif

Sorted Z-values of Cbl motif

Promoter Log-likelihood Transcript Gene Gene Info
ssuEADCB 5.77 NADPH-dependent FMN reductase
alkanesulfonate monooxygenase, FMNH2-dependent
aliphatic sulfonate ABC transporter - periplasmic binding protein
aliphatic sulfonate ABC transporter - membrane subunit
aliphatic sulfonate ABC transporter - ATP binding subunit
tauABCD 1.95 taurine ABC transporter - ATP binding subunit
taurine ABC transporter - membrane subunit
taurine ABC transporter - periplasmic binding protein
taurine dioxygenase

Network of associatons between targets according to the STRING database.

First level regulatory network of Cbl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0009970 cellular response to sulfate starvation(GO:0009970) xenobiotic transport(GO:0042908)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.8 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.1 1.9 GO:1904949 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0004497 monooxygenase activity(GO:0004497)
0.6 1.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)