ISMARA results: Cbl

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for Cbl

Z-value: 0.75

Transcription factors associated with Cbl

Gene Symbol	Gene ID	Gene Info
cbl RegulonDB EcoCyc	cbl	Cbl DNA-binding transcriptional activator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
cbl		1.00	4.0e-09	Click!

Activity profile of Cbl motif

Sorted Z-values of Cbl motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
ssuEADCB Show fit	5.77		ssuE RegulonDB EcoCyc Show fit ssuD RegulonDB EcoCyc Show fit ssuA RegulonDB EcoCyc Show fit ssuC RegulonDB EcoCyc Show fit ssuB RegulonDB EcoCyc Show fit	NADPH-dependent FMN reductase alkanesulfonate monooxygenase, FMNH₂-dependent aliphatic sulfonate ABC transporter - periplasmic binding protein aliphatic sulfonate ABC transporter - membrane subunit aliphatic sulfonate ABC transporter - ATP binding subunit
tauABCD Show fit	1.95		tauB RegulonDB EcoCyc Show fit tauC RegulonDB EcoCyc Show fit tauA RegulonDB EcoCyc Show fit tauD RegulonDB EcoCyc Show fit	taurine ABC transporter - ATP binding subunit taurine ABC transporter - membrane subunit taurine ABC transporter - periplasmic binding protein taurine dioxygenase

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Network of associatons between targets according to the STRING database.

First level regulatory network of Cbl

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.7	GO:0009970	cellular response to sulfate starvation(GO:0009970) xenobiotic transport(GO:0042908)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.8	GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.1	1.9	GO:1904949	ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.9	5.8	GO:0004497	monooxygenase activity(GO:0004497)
0.6	1.9	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)

Showing 1 to 2 of 2 entries

Results for Cbl

Z-value: 0.75

Transcription factors associated with Cbl

Activity-expression correlation:

Activity profile of Cbl motif

Sorted Z-values of Cbl motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cbl

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: