ISMARA results: CaiF

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for CaiF

Z-value: 1.25

Transcription factors associated with CaiF

Gene Symbol	Gene ID	Gene Info
caiF RegulonDB EcoCyc	caiF	CaiF transcriptional activator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
caiF		0.71	5.1e-02	Click!

Activity profile of CaiF motif

Sorted Z-values of CaiF motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
fixABCX Show fit	11.82		fixC RegulonDB EcoCyc Show fit fixB RegulonDB EcoCyc Show fit fixA RegulonDB EcoCyc Show fit fixX RegulonDB EcoCyc Show fit	flavoprotein (electron transport), possibly involved in anaerobic carnitine metabolism predicted electron transfer flavoprotein, NAD/FAD-binding domain and ETFP adenine nucleotide-binding domain-like predicted elecron transfer flavoprotein subunit, ETFP adenine nucleotide-binding domain putative ferredoxin possibly involved in anaerobic carnitine metabolism
caiTABCDE Show fit	10.01		caiT RegulonDB EcoCyc Show fit caiE RegulonDB EcoCyc Show fit caiD RegulonDB EcoCyc Show fit caiC RegulonDB EcoCyc Show fit caiB RegulonDB EcoCyc Show fit caiA RegulonDB EcoCyc Show fit	L-carnitine : γ-butyrobetaine antiporter predicted acyl transferase crotonobetainyl-CoA hydratase carnitine-CoA ligase γ-butyrobetainyl-CoA:carnitine CoA transferase crotonobetainyl-CoA reductase

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Network of associatons between targets according to the STRING database.

First level regulatory network of CaiF

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
7.3	21.8	GO:0009437	carnitine metabolic process(GO:0009437)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	11.8	GO:0005829	cytosol(GO:0005829)
0.0	10.0	GO:0016021	integral component of membrane(GO:0016021)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.3	11.8	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
3.3	10.0	GO:0015651	amino-acid betaine transmembrane transporter activity(GO:0015199) quaternary ammonium group transmembrane transporter activity(GO:0015651)

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Results for CaiF

Z-value: 1.25

Transcription factors associated with CaiF

Activity-expression correlation:

Activity profile of CaiF motif

Sorted Z-values of CaiF motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CaiF

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: