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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for BolA

Z-value: 0.62

Transcription factors associated with BolA

Gene Symbol Gene ID Gene Info
bolA
bolA BolA DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bolA-0.921.4e-03Click!

Activity profile of BolA motif

Sorted Z-values of BolA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ampC 4.64
ampC
β-lactamase; penicillin resistance
dacC 0.51
dacC
penicillin-binding protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of BolA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0000902 cell morphogenesis(GO:0000902) regulation of cell shape(GO:0008360) anatomical structure morphogenesis(GO:0009653) regulation of anatomical structure morphogenesis(GO:0022603) regulation of cell morphogenesis(GO:0022604) cellular component morphogenesis(GO:0032989) single-organism developmental process(GO:0044767) anatomical structure development(GO:0048856) cellular developmental process(GO:0048869) regulation of developmental process(GO:0050793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 0.5 GO:0008658 penicillin binding(GO:0008658)