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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for ArgP

Z-value: 0.70

Transcription factors associated with ArgP

Gene Symbol Gene ID Gene Info
argP ArgP transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
argP0.541.7e-01Click!

Activity profile of ArgP motif

Sorted Z-values of ArgP motif

Promoter Log-likelihood Transcript Gene Gene Info
argO 2.57 L-arginine exporter
lysC 1.68 aspartate kinase III
lysP 1.28 lysine:H+ symporter
lysA 0.95 diaminopimelate decarboxylase
dapB 0.47 4-hydroxy-tetrahydrodipicolinate reductase
argP 0.17 ArgP transcriptional activator
dnaAN-recF 0.14 chromosomal replication initiator protein DnaA; DNA-binding transcriptional dual regulator
ssDNA and dsDNA binding, ATP binding
DNA polymerase III, β subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of ArgP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0009090 homoserine biosynthetic process(GO:0009090) homoserine metabolic process(GO:0009092)
0.5 2.6 GO:0015809 arginine transport(GO:0015809) L-arginine transport(GO:1902023)
0.4 1.3 GO:0015819 lysine transport(GO:0015819) L-lysine transport(GO:1902022)
0.2 1.0 GO:0009089 lysine biosynthetic process via diaminopimelate(GO:0009089)
0.1 0.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.1 0.2 GO:2000104 regulation of DNA-dependent DNA replication initiation(GO:0030174) negative regulation of DNA-dependent DNA replication(GO:2000104)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.6 1.7 GO:0004072 aspartate kinase activity(GO:0004072) amino acid kinase activity(GO:0019202)
0.1 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0003681 bent DNA binding(GO:0003681)