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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for znf148
Z-value: 0.29
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Transcription factors associated with znf148
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| znf148 | dr11_v1_chr9_+_38629962_38629962 | 0.88 | 1.5e-06 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_233143 Show fit | 2.23 |
ENSDART00000175273
|
synaptic Ras GTPase activating protein 1a |
|
| chr22_-_36934040 Show fit | 1.32 |
ENSDART00000151666
|
Pim proto-oncogene, serine/threonine kinase, related 206 |
|
| chr5_-_26118855 Show fit | 0.75 |
ENSDART00000009028
|
elastase 3 like |
|
| chr17_-_52521002 Show fit | 0.67 |
ENSDART00000114931
|
prospero homeobox 2 |
|
| chr25_-_16554757 Show fit | 0.63 |
ENSDART00000154480
|
si:ch211-266k8.6 |
|
| chr2_+_6181383 Show fit | 0.57 |
ENSDART00000153307
|
si:ch73-344o19.1 |
|
| chr3_-_61592417 Show fit | 0.55 |
ENSDART00000155082
|
neuronal pentraxin 2a |
|
| chr11_-_18705303 Show fit | 0.54 |
ENSDART00000059732
|
inhibitor of DNA binding 1 |
|
| chr6_+_12865137 Show fit | 0.51 |
ENSDART00000090065
|
family with sequence similarity 117, member Ba |
|
| chr17_+_6667441 Show fit | 0.50 |
ENSDART00000123503
ENSDART00000180381 ENSDART00000156140 |
structural maintenance of chromosomes 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of znf148
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.0 | 0.5 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.0 | 0.4 | GO:0043363 | nucleate erythrocyte differentiation(GO:0043363) |
| 0.1 | 0.3 | GO:0090247 | hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248) |
| 0.0 | 0.3 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.0 | 0.3 | GO:1903288 | positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.0 | 0.3 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 0.2 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.1 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.1 | GO:0006843 | mitochondrial citrate transport(GO:0006843) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.4 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.0 | 0.3 | GO:0014704 | intercalated disc(GO:0014704) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0008026 | ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.1 | 0.3 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.0 | 0.3 | GO:0001217 | bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217) |
| 0.0 | 0.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.3 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.2 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.1 | GO:0005252 | open rectifier potassium channel activity(GO:0005252) |
| 0.0 | 0.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.4 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.2 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |