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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for zgc:101100

Z-value: 0.29

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Transcription factors associated with zgc:101100

Gene Symbol Gene ID Gene Info
zgc
ENSDARG00000021959 101100

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zgc:101100dr11_v1_chr8_+_20488322_204883220.823.3e-05Click!

Activity profile of zgc:101100 motif

Sorted Z-values of zgc:101100 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_2841205 0.70 ENSDART00000131505
ENSDART00000055869
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr8_+_2656231 0.58 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr1_-_44928987 0.53 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr8_+_2656681 0.52 ENSDART00000185067
ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr21_-_9562272 0.49 ENSDART00000162225
ENSDART00000163874
ENSDART00000168173
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr7_+_66884291 0.48 ENSDART00000187499
sbf2
SET binding factor 2
chr2_-_58075414 0.46 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr6_-_17999776 0.46 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr22_-_20695237 0.46 ENSDART00000112722
org
oogenesis-related gene
chr18_+_49969568 0.46 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr16_+_16265850 0.45 ENSDART00000181265
setd2
SET domain containing 2
chr3_-_23513155 0.44 ENSDART00000170200
BX682558.1

chr19_+_24068223 0.41 ENSDART00000141351
ENSDART00000100420
pex11b
peroxisomal biogenesis factor 11 beta
chr5_-_24029228 0.41 ENSDART00000051546
rps6ka3a
ribosomal protein S6 kinase a, polypeptide 3a
chr7_+_66884570 0.39 ENSDART00000082664
sbf2
SET binding factor 2
chr8_-_11016766 0.37 ENSDART00000064066
bcas2
BCAS2, pre-mRNA processing factor
chr20_-_25643667 0.35 ENSDART00000137457
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr9_-_34500197 0.34 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr13_-_36525982 0.33 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr8_-_25814263 0.31 ENSDART00000143397
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_-_28275600 0.31 ENSDART00000170094
creb1b
cAMP responsive element binding protein 1b
chr17_+_35097024 0.29 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr20_+_34671386 0.27 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr2_-_9696283 0.26 ENSDART00000165712
selenot1a
selenoprotein T, 1a
chr24_-_25004553 0.26 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr11_+_31680513 0.26 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr15_-_26887028 0.25 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr22_+_438714 0.23 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr22_+_34701848 0.22 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr2_-_30784198 0.21 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr2_+_30531726 0.21 ENSDART00000146518
ankrd33bb
ankyrin repeat domain 33Bb
chr21_+_44773237 0.18 ENSDART00000084780
rnf121
ring finger protein 121
chr16_+_11297703 0.18 ENSDART00000125158
znf574
zinc finger protein 574
chr7_-_57933736 0.17 ENSDART00000142580
ank2b
ankyrin 2b, neuronal
chr7_-_49594995 0.16 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr5_+_31791001 0.16 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr18_-_38245062 0.15 ENSDART00000189092
nat10
N-acetyltransferase 10
chr25_-_32381642 0.15 ENSDART00000133872
ENSDART00000006124
cops2
COP9 signalosome subunit 2
chr14_+_30753666 0.15 ENSDART00000009385
ENSDART00000137782
ENSDART00000172778
yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr24_+_37533728 0.14 ENSDART00000061203
rhot2
ras homolog family member T2
chr12_+_33460794 0.14 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr5_+_47882319 0.14 ENSDART00000149316
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr21_-_41369370 0.13 ENSDART00000159290
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr10_+_6013076 0.12 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr6_-_59381391 0.12 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr2_+_30787128 0.12 ENSDART00000189233
atp6v1h
ATPase H+ transporting V1 subunit H
chr14_+_32838110 0.12 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr3_-_10970502 0.12 ENSDART00000127500
CR382337.1

chr2_+_30786773 0.12 ENSDART00000019029
ENSDART00000145681
atp6v1h
ATPase H+ transporting V1 subunit H
chr5_-_38107741 0.11 ENSDART00000156853
si:ch211-284e13.14
si:ch211-284e13.14
chr6_+_13083146 0.11 ENSDART00000172158
l3hypdh
trans-L-3-hydroxyproline dehydratase
chr23_-_10137322 0.10 ENSDART00000142442
plxnb1a
plexin b1a
chr11_+_25583950 0.10 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr24_-_7777389 0.10 ENSDART00000138541
rpgrip1
RPGR interacting protein 1
chr19_+_2631565 0.10 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr1_+_41690402 0.10 ENSDART00000177298
fbxo41
F-box protein 41
chr10_+_17026870 0.09 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr13_+_1015749 0.09 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr15_+_42995381 0.08 ENSDART00000152222
acsl3a
acyl-CoA synthetase long chain family member 3a
chr14_+_32837914 0.08 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr8_-_14121634 0.07 ENSDART00000184946
bgna
biglycan a
chr2_+_4146299 0.06 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr18_-_25646286 0.06 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2
si:ch211-13k12.2
chr17_-_50010121 0.05 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr6_-_33924883 0.04 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr19_-_40906161 0.04 ENSDART00000004514
bet1
Bet1 golgi vesicular membrane trafficking protein
chr22_+_35275468 0.04 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr11_+_37909654 0.04 ENSDART00000172211
si:ch211-112f3.4
si:ch211-112f3.4
chr21_-_2348838 0.03 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr18_+_7639401 0.03 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr2_+_4146606 0.03 ENSDART00000171170
mib1
mindbomb E3 ubiquitin protein ligase 1
chr25_-_17503393 0.03 ENSDART00000061726
trim35-40
tripartite motif containing 35-40
chr8_-_54077740 0.03 ENSDART00000027000
rho
rhodopsin
chr23_-_18981595 0.03 ENSDART00000147617
bcl2l1
bcl2-like 1
chr1_-_45146834 0.02 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr12_+_6195191 0.02 ENSDART00000043236
ENSDART00000186420
prkg1b
protein kinase, cGMP-dependent, type Ib
chr11_-_15090118 0.02 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr17_-_2690083 0.02 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr17_-_51202339 0.01 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr19_+_4061699 0.01 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr7_-_17780048 0.01 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr20_-_18736281 0.00 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr9_+_21990095 0.00 ENSDART00000146829
ENSDART00000133515
ENSDART00000193582
si:dkey-57a22.13
si:dkey-57a22.13
chr11_+_30296332 0.00 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7

Network of associatons between targets according to the STRING database.

First level regulatory network of zgc:101100

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.3 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.2 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.5 GO:0038202 TORC1 signaling(GO:0038202) cellular response to amino acid stimulus(GO:0071230)
0.0 0.0 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling