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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for zbtb47b+znf652
Z-value: 1.01
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Transcription factors associated with zbtb47b+znf652
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| zbtb47b | dr11_v1_chr24_-_20641000_20641000 | -0.96 | 4.2e-10 | Click! |
| znf652 | dr11_v1_chr3_+_15773991_15773991 | -0.92 | 5.8e-08 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_38643188 Show fit | 2.94 |
ENSDART00000144972
|
si:ch211-271e10.1 |
|
| chr20_-_52631998 Show fit | 2.76 |
ENSDART00000145283
ENSDART00000139072 |
si:ch211-221n20.1 |
|
| chr14_+_45565891 Show fit | 2.46 |
ENSDART00000133389
ENSDART00000025549 |
zgc:92249 |
|
| chr11_-_3959889 Show fit | 2.45 |
ENSDART00000159683
|
polybromo 1 |
|
| chr16_-_29557338 Show fit | 2.41 |
ENSDART00000058888
|
HORMA domain containing 1 |
|
| chr5_+_37978501 Show fit | 2.38 |
ENSDART00000012050
|
apolipoprotein A-Ia |
|
| chr10_+_44042033 Show fit | 2.10 |
ENSDART00000190006
ENSDART00000046172 |
crystallin, beta A4 |
|
| chr7_-_19544575 Show fit | 2.07 |
ENSDART00000161549
|
si:ch211-212k18.11 |
|
| chr20_-_52666150 Show fit | 1.99 |
ENSDART00000146716
ENSDART00000134155 |
si:ch211-221n20.4 |
|
| chr6_-_2627488 Show fit | 1.99 |
ENSDART00000044089
ENSDART00000158333 ENSDART00000155109 |
hydroxypyruvate isomerase |
Network of associatons between targets according to the STRING database.
First level regulatory network of zbtb47b+znf652
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.0 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 0.1 | 3.9 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.9 | 3.4 | GO:1904355 | positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355) |
| 0.0 | 2.5 | GO:0007601 | visual perception(GO:0007601) |
| 0.8 | 2.4 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.5 | 2.4 | GO:0010872 | regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) |
| 0.3 | 2.0 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 0.0 | 1.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.2 | 1.7 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.1 | 1.7 | GO:0042119 | granulocyte activation(GO:0036230) neutrophil activation(GO:0042119) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.9 | GO:0016586 | RSC complex(GO:0016586) |
| 0.2 | 2.4 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 1.7 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 1.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 1.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 1.5 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 1.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 1.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.1 | 1.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 1.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.2 | 2.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.5 | 2.4 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.0 | 1.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.8 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 1.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.4 | 1.7 | GO:0005153 | interleukin-8 receptor binding(GO:0005153) |
| 0.0 | 1.7 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.1 | 1.5 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 1.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.8 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.5 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.2 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.0 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 2.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 1.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.2 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.0 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.0 | 0.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 0.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |