Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for thraa+thrab

Z-value: 0.90

Motif logo

Transcription factors associated with thraa+thrab

Gene Symbol Gene ID Gene Info
ENSDARG00000000151 thyroid hormone receptor alpha a
ENSDARG00000052654 thyroid hormone receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
thraadr11_v1_chr3_-_34724879_34724879-0.912.2e-07Click!
thrabdr11_v1_chr12_-_22039350_22039350-0.823.6e-05Click!

Activity profile of thraa+thrab motif

Sorted Z-values of thraa+thrab motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_57311901 2.90 ENSDART00000149397
mycbp associated protein
chr17_-_24838927 2.42 ENSDART00000123259

chr12_+_49125510 2.15 ENSDART00000185804

chr16_-_42969598 1.98 ENSDART00000156011
si:ch211-135n15.3
chr4_+_18489207 1.98 ENSDART00000135276
si:dkey-202b22.5
chr20_-_43462190 1.85 ENSDART00000100697
Pim proto-oncogene, serine/threonine kinase, related 133
chr25_+_4954220 1.80 ENSDART00000156034
si:ch73-265h17.2
chr5_+_13353866 1.72 ENSDART00000099611
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr6_+_475264 1.67 ENSDART00000193615

chr7_-_40738774 1.65 ENSDART00000084179
ring finger protein 32
chr20_+_42761881 1.64 ENSDART00000113625
Pim proto-oncogene, serine/threonine kinase, related 113
chr22_-_20761759 1.63 ENSDART00000013803
anti-Mullerian hormone
chr13_-_36703164 1.57 ENSDART00000044357
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr20_+_39457598 1.56 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr1_-_30039331 1.50 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr20_+_54738210 1.45 ENSDART00000151399
p21 protein (Cdc42/Rac)-activated kinase 7
chr16_-_41867833 1.44 ENSDART00000133066
zgc:194418
chr14_-_24397718 1.43 ENSDART00000110164
si:ch211-163m17.4
chr10_-_44027391 1.39 ENSDART00000145404
crystallin, beta B1
chr20_+_42780162 1.37 ENSDART00000127069
Pim proto-oncogene, serine/threonine kinase, related 213
chr16_-_41840668 1.33 ENSDART00000146150
si:dkey-199f5.4
chr11_-_6001845 1.32 ENSDART00000108628
anoctamin 8b
chr20_-_43572763 1.25 ENSDART00000153251
Pim proto-oncogene, serine/threonine kinase, related 125
chr24_-_39610585 1.25 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr14_+_39255437 1.23 ENSDART00000147443
diaphanous-related formin 2
chr13_+_8677166 1.22 ENSDART00000181016
ENSDART00000135028
PROP paired-like homeobox 1
chr9_+_52613820 1.19 ENSDART00000168753
ENSDART00000165580
ENSDART00000164769
si:ch211-241j8.2
chr2_+_6181383 1.18 ENSDART00000153307
si:ch73-344o19.1
chr12_-_47782623 1.17 ENSDART00000115742
selenoprotein U1b
chr14_-_8724290 1.15 ENSDART00000161171
Pim proto-oncogene, serine/threonine kinase, related 56
chr19_+_3653976 1.12 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr15_-_28095532 1.11 ENSDART00000191490
crystallin, beta A1a
chr12_+_18533198 1.10 ENSDART00000189729
meiosis specific with OB domains
chr23_+_42810055 1.09 ENSDART00000186647
myosin, light chain 9a, regulatory
chr8_+_25902170 1.07 ENSDART00000193130
ras homolog gene family, member Ab
chr12_-_3133483 1.06 ENSDART00000015092
collagen, type I, alpha 1b
chr11_-_31172276 1.05 ENSDART00000171520
si:dkey-238i5.3
chr13_+_51869025 1.04 ENSDART00000187066

chr21_-_45073764 1.00 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr1_+_54626491 0.96 ENSDART00000136063
si:ch211-202h22.9
chr12_+_7491690 0.95 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr10_+_26813710 0.94 ENSDART00000136122
si:ch211-263p13.7
chr18_-_15932704 0.93 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr23_+_4373360 0.93 ENSDART00000144061
protein tyrosine phosphatase domain containing 1b
chr5_+_7989210 0.92 ENSDART00000168071
glial cell derived neurotrophic factor b
chr2_+_49864219 0.92 ENSDART00000187744
ribosomal protein L37
chr5_-_26118855 0.92 ENSDART00000009028
elastase 3 like
chr4_+_17280868 0.91 ENSDART00000145349
branched chain amino-acid transaminase 1, cytosolic
chr13_-_31435137 0.89 ENSDART00000057441
reticulon 1a
chr16_-_45327616 0.89 ENSDART00000158733
si:dkey-33i11.1
chr11_-_11471857 0.87 ENSDART00000030103
keratin 94
chr6_+_30689239 0.86 ENSDART00000065206
WD repeat domain 78
chr2_+_24786765 0.85 ENSDART00000141030
phosphodiesterase 4C, cAMP-specific a
chr2_+_33368414 0.84 ENSDART00000077462
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr23_+_44634187 0.84 ENSDART00000143688
si:ch73-265d7.2
chr1_-_59176949 0.82 ENSDART00000128742

chr7_+_26716321 0.81 ENSDART00000189750
CD82 molecule a
chr8_-_6918721 0.80 ENSDART00000014915
ankyrin repeat and SOCS box containing 6
chr4_-_9609634 0.79 ENSDART00000067188
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr8_-_6918290 0.77 ENSDART00000138259
ENSDART00000142496
ankyrin repeat and SOCS box containing 6
chr6_+_41463786 0.76 ENSDART00000065006
twinfilin actin-binding protein 2a
chr8_-_48675411 0.75 ENSDART00000165081
Pim proto-oncogene, serine/threonine kinase, related 183
chr5_-_32882162 0.74 ENSDART00000085769
leucine rich repeat and sterile alpha motif containing 1
chr12_+_18532866 0.74 ENSDART00000152126
ENSDART00000152443
ENSDART00000089589
meiosis specific with OB domains
chr4_+_38344 0.73 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr3_-_38915998 0.70 ENSDART00000141886
si:dkey-106c17.2
chr12_-_30841679 0.69 ENSDART00000105594
crystallin, gamma MX
chr10_+_22782522 0.69 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
chr10_+_8629275 0.68 ENSDART00000129643
apelin receptor b
chr21_-_8420830 0.67 ENSDART00000138040
LIM homeobox 2a
chr2_+_36015049 0.66 ENSDART00000158276
laminin, gamma 2
chr20_-_40717900 0.64 ENSDART00000181663
connexin 43
chr11_+_6010177 0.64 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr16_+_38338721 0.63 ENSDART00000076528
ENSDART00000142885
GA binding protein transcription factor, beta subunit 2b
chr4_-_16853464 0.61 ENSDART00000125743
ENSDART00000164570
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr7_-_37812176 0.60 ENSDART00000164485
adenylate cyclase 7
chr7_-_41627956 0.58 ENSDART00000083929
plexin domain containing 2
chr3_-_18575868 0.58 ENSDART00000122968
aquaporin 8b
chr9_-_202805 0.57 ENSDART00000182260

chr18_+_3530769 0.57 ENSDART00000163469
si:ch73-338a16.3
chr22_-_38258053 0.56 ENSDART00000132516
ELAV like neuron-specific RNA binding protein 2
chr6_+_1787160 0.55 ENSDART00000113505
myosin, light chain 9b, regulatory
chr4_-_16412084 0.54 ENSDART00000188460
decorin
chr7_-_11638126 0.54 ENSDART00000125827
si:dkey-15b23.3
chr5_-_67661102 0.54 ENSDART00000013605
zinc finger and BTB domain containing 20
chr2_-_43123949 0.52 ENSDART00000075347
ENSDART00000132346
leucine rich repeat containing 6
chr17_+_6217704 0.51 ENSDART00000129100

chr8_+_53269657 0.50 ENSDART00000184212
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr2_-_53481912 0.49 ENSDART00000189610
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr3_-_29977495 0.49 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr4_-_1360495 0.49 ENSDART00000164623
pleiotrophin
chr18_-_26675699 0.48 ENSDART00000113280
si:ch211-69m14.1
chr7_-_26308098 0.47 ENSDART00000146440
ENSDART00000146935
ENSDART00000164627
zgc:77439
chr17_-_15149192 0.47 ENSDART00000180511
ENSDART00000103405
GTP cyclohydrolase 1
chr19_+_4912817 0.47 ENSDART00000101658
ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_+_33655890 0.46 ENSDART00000143757
four and a half LIM domains 3a
chr20_-_7992496 0.46 ENSDART00000145521
phospholipid phosphatase 3
chr21_-_41870029 0.45 ENSDART00000182035
endonuclease, polyU-specific 2
chr23_+_44633858 0.45 ENSDART00000180728
si:ch73-265d7.2
chr3_-_37681824 0.45 ENSDART00000185858
G patch domain containing 8
chr23_+_30048849 0.44 ENSDART00000126027
urotensin 2, alpha
chr12_-_37653685 0.44 ENSDART00000085121
sidekick cell adhesion molecule 2b
chr11_+_12897004 0.44 ENSDART00000152007
si:dkey-11m19.5
chr22_-_15578402 0.43 ENSDART00000062986
hematopoietic SH2 domain containing
chr15_+_24644016 0.43 ENSDART00000043292
smoothelin, like
chr16_-_13612650 0.43 ENSDART00000080372
D site albumin promoter binding protein b
chr11_-_22997506 0.43 ENSDART00000167817
ATPase plasma membrane Ca2+ transporting 2
chr3_+_12484008 0.43 ENSDART00000182229
vasorin b
chr8_+_20776654 0.43 ENSDART00000135850
nuclear factor I/C
chr6_-_49873020 0.42 ENSDART00000148511
GNAS complex locus
chr11_+_45421761 0.42 ENSDART00000167347
HRAS-like suppressor
chr19_-_7043355 0.42 ENSDART00000104845
TAP binding protein (tapasin), tandem duplicate 1
chr7_+_29133321 0.41 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr23_-_42810664 0.41 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr13_+_18663600 0.41 ENSDART00000141647
selenoprotein U 1a
chr14_+_28438947 0.40 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr3_+_13440900 0.39 ENSDART00000143715
si:dkey-117i10.1
chr1_-_46343999 0.39 ENSDART00000145117
ENSDART00000193233
ATPase phospholipid transporting 11A
chr5_-_69425224 0.39 ENSDART00000158096

chr25_-_36492779 0.39 ENSDART00000042271
iroquois homeobox 3b
chr5_-_56412262 0.38 ENSDART00000083079
acetyl-CoA carboxylase alpha
chr14_-_46675850 0.37 ENSDART00000113285
transmembrane anterior posterior transformation 1a
chr1_-_58975098 0.37 ENSDART00000189899

chr25_-_29134654 0.36 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr2_-_127945 0.36 ENSDART00000056453
insulin-like growth factor binding protein 1b
chr25_+_37443194 0.35 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr5_-_23473312 0.35 ENSDART00000140310
si:dkeyp-20g2.3
chr25_-_15214161 0.34 ENSDART00000031499
wilms tumor 1a
chr23_+_41912151 0.34 ENSDART00000191115
podocan
chr5_-_51747278 0.34 ENSDART00000192232
LHFPL tetraspan subfamily member 2b
chr17_+_24613255 0.34 ENSDART00000064738
ATP synthase inhibitory factor subunit 1b
chr15_+_28096152 0.34 ENSDART00000100293
ENSDART00000140092
crystallin, beta B1, like 3
chr3_-_36612877 0.33 ENSDART00000167164
si:dkeyp-72e1.7
chr7_-_30082931 0.33 ENSDART00000075600
tetraspanin 3b
chr7_+_31871830 0.33 ENSDART00000139899
myosin binding protein C, cardiac
chr6_+_33885828 0.32 ENSDART00000179994
GC-rich promoter binding protein 1-like 1
chr17_+_53424415 0.31 ENSDART00000157022
solute carrier family 9 member A1b
chr8_+_28259347 0.31 ENSDART00000110857
family with sequence similarity 212, member B
chr19_-_18855717 0.31 ENSDART00000158192
palmitoyl-protein thioesterase 2
chr23_+_24272421 0.30 ENSDART00000029974
chloride channel K
chr9_-_9225980 0.30 ENSDART00000180301
cystathionine-beta-synthase b
chr8_+_23711842 0.30 ENSDART00000128783
peroxisome proliferator-activated receptor delta b
chr16_+_5774977 0.29 ENSDART00000134202
cholecystokinin a
chr9_-_374693 0.29 ENSDART00000166571
si:dkey-11f4.7
chr12_-_42397002 0.28 ENSDART00000160497
glutaredoxin 3
chr11_+_6819050 0.27 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr10_+_44146287 0.26 ENSDART00000162176
G protein-coupled receptor kinase 3
chr5_-_67629263 0.26 ENSDART00000133753
zinc finger and BTB domain containing 20
chr6_-_60031693 0.26 ENSDART00000160275

chr25_-_5740334 0.26 ENSDART00000169622
ENSDART00000168720

chr2_-_6182098 0.26 ENSDART00000156167
si:ch73-182a11.2
chr3_+_1942219 0.26 ENSDART00000114520
zgc:165583
chr9_-_22892838 0.26 ENSDART00000143888
nebulin
chr18_+_17959681 0.25 ENSDART00000142700
zinc finger protein 423
chr4_-_77432218 0.25 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr14_+_36738069 0.25 ENSDART00000105590
tryptophan 2,3-dioxygenase a
chr17_+_22587356 0.25 ENSDART00000157328
baculoviral IAP repeat containing 6
chr10_-_39153959 0.24 ENSDART00000150193
ENSDART00000111362
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr16_-_46605160 0.24 ENSDART00000189070
ENSDART00000181194
transmembrane protein 176l.3a
chr2_-_44199722 0.24 ENSDART00000140633
ENSDART00000145728
succinate dehydrogenase complex, subunit C, integral membrane protein
chr3_+_12710350 0.24 ENSDART00000157959
cytochrome P450, family 2, subfamily K, polypeptide 18
chr23_-_20429741 0.23 ENSDART00000104334
TATA-box binding protein associated factor 13
chr5_+_4564233 0.23 ENSDART00000193435

chr11_-_25213651 0.23 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr18_-_26785861 0.23 ENSDART00000098361
neuromedin Ba
chr8_+_7097740 0.22 ENSDART00000159670
ankyrin repeat and BTB (POZ) domain containing 1
chr11_+_25477643 0.22 ENSDART00000065941
opsin 1 (cone pigments), long-wave-sensitive, 1
chr13_-_31878043 0.22 ENSDART00000187720
synaptotagmin XIVa
chr10_-_30785501 0.21 ENSDART00000020054
opioid binding protein/cell adhesion molecule-like
chr7_+_20017211 0.21 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr2_-_28102264 0.21 ENSDART00000013638
cadherin 6
chr13_-_31878263 0.21 ENSDART00000180411
synaptotagmin XIVa
chr19_-_24443867 0.21 ENSDART00000163763
ENSDART00000043133
thrombospondin 3b
chr1_+_2112726 0.21 ENSDART00000131714
ENSDART00000138396
muscleblind-like splicing regulator 2
chr23_-_3703569 0.21 ENSDART00000143731
protein kinase C and casein kinase substrate in neurons 1a
chr11_-_3574311 0.20 ENSDART00000167064
si:dkey-33m11.7
chr1_-_49250490 0.20 ENSDART00000150386
si:ch73-6k14.2
chr1_+_23783349 0.20 ENSDART00000007531
slit homolog 2 (Drosophila)
chr10_+_17592273 0.20 ENSDART00000141221
si:dkey-76p7.5
chr10_+_5422575 0.20 ENSDART00000063093
AU RNA binding protein/enoyl-CoA hydratase
chr17_-_51829310 0.20 ENSDART00000154544
numb homolog (Drosophila)
chr20_-_25877793 0.20 ENSDART00000177333
ENSDART00000184619
exocyst complex component 1
chr14_-_34771371 0.20 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr18_-_16924221 0.20 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr9_+_38458193 0.20 ENSDART00000008053
minichromosome maintenance complex component 3 associated protein
chr6_-_51556308 0.19 ENSDART00000149033
retinoblastoma-like 1 (p107)
chr13_-_30645965 0.19 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr19_-_24443394 0.19 ENSDART00000090825
thrombospondin 3b
chr6_-_1566581 0.19 ENSDART00000192993
tripartite motif containing 107
chr24_-_1356668 0.19 ENSDART00000188935
neuropilin 1a
chr10_-_42923385 0.19 ENSDART00000076731
acyl-CoA thioesterase 12
chr21_+_22738939 0.19 ENSDART00000151342
ENSDART00000079145
Rho GTPase activating protein 42a
chr7_-_50604626 0.19 ENSDART00000073903
ENSDART00000174031
CREB regulated transcription coactivator 3
chr3_+_17030665 0.18 ENSDART00000159849
ENSDART00000174491
ENSDART00000104519
ENSDART00000080854
signal transducer and activator of transcription 3 (acute-phase response factor)
chr5_-_30535327 0.18 ENSDART00000040328
H2A histone family, member X
chr11_-_1400507 0.18 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
ribosomal protein L29
chr8_-_39754621 0.17 ENSDART00000149243
si:ch211-170d8.8
chr24_-_7995748 0.17 ENSDART00000158566
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr19_-_6988837 0.17 ENSDART00000145741
ENSDART00000167640
zinc finger protein 384 like
chr4_+_75314247 0.17 ENSDART00000162365

Network of associatons between targets according to the STRING database.

First level regulatory network of thraa+thrab

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.3 0.9 GO:0061217 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 0.8 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 0.9 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.2 0.7 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 1.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0072149 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.2 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1 0.2 GO:0090008 hypoblast development(GO:0090008)
0.1 1.2 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.2 GO:1905208 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.4 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 1.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.2 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.4 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0003315 heart rudiment formation(GO:0003315)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 9.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.5 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 1.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.1 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.6 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.7 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0000801 central element(GO:0000801)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 0.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 0.9 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.2 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1