Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for tfe3a+tfe3b

Z-value: 0.49

Motif logo

Transcription factors associated with tfe3a+tfe3b

Gene Symbol Gene ID Gene Info
ENSDARG00000019457 transcription factor binding to IGHM enhancer 3b
ENSDARG00000098903 transcription factor binding to IGHM enhancer 3a
ENSDARG00000111231 transcription factor binding to IGHM enhancer 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfe3adr11_v1_chr8_+_7778770_7778770-0.762.5e-04Click!
tfe3bdr11_v1_chr11_+_25508129_255081290.446.6e-02Click!

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_4539899 2.47 ENSDART00000112460
dolichol kinase
chr13_-_3474373 1.86 ENSDART00000157437
parkin RBR E3 ubiquitin protein ligase
chr20_-_54014539 1.12 ENSDART00000060466
si:dkey-241l7.6
chr8_-_17167819 1.02 ENSDART00000135042
ENSDART00000143920
mitochondrial ribosomal protein S36
chr15_+_1199407 0.83 ENSDART00000163827
major facilitator superfamily domain containing 1
chr15_-_17099560 0.83 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr6_+_153146 0.77 ENSDART00000097468
zinc finger, GATA-like protein 1
chr23_+_31913292 0.76 ENSDART00000136910
armadillo repeat containing 1, like
chr23_+_26079467 0.74 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr20_-_25631256 0.73 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr11_+_7183025 0.73 ENSDART00000046670
ENSDART00000154009
ENSDART00000156974
ENSDART00000125619
thimet oligopeptidase 1
chr10_+_14963898 0.71 ENSDART00000187363
ENSDART00000175732
si:dkey-88l16.3
chr2_-_42360329 0.71 ENSDART00000144274
ENSDART00000140863
si:dkey-7l6.3
chr3_+_39568290 0.70 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr3_+_23029934 0.67 ENSDART00000110343
N-acetylglutamate synthase
chr18_+_41542542 0.66 ENSDART00000087445
TSEN34 tRNA splicing endonuclease subunit
chr19_+_7152966 0.65 ENSDART00000080348
bromodomain containing 2a
chr21_+_4540127 0.65 ENSDART00000043431
nucleoporin 188
chr17_-_25331439 0.64 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr7_-_8324927 0.64 ENSDART00000102535
coagulation factor XIII, A1 polypeptide b
chr1_-_18811517 0.63 ENSDART00000142026
si:dkey-167i21.2
chr25_+_21716263 0.62 ENSDART00000148920
zinc finger protein 277
chr1_-_47114310 0.61 ENSDART00000144899
ENSDART00000053157
SET domain containing 4
chr19_-_1947403 0.61 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr20_+_7584211 0.61 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr7_-_11383933 0.60 ENSDART00000163949
mesoderm development LRP chaperone
chr3_+_3454610 0.59 ENSDART00000024900
zgc:165453
chr11_-_26590401 0.57 ENSDART00000154349
ENSDART00000123094
ST3 beta-galactoside alpha-2,3-sialyltransferase 8
chr11_+_42730639 0.56 ENSDART00000165297
zgc:194981
chr3_-_3439150 0.56 ENSDART00000021286
si:dkey-46g23.5
chr9_-_3149896 0.56 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr12_+_34891529 0.55 ENSDART00000015643
tubulin folding cofactor C
chr7_-_11384279 0.55 ENSDART00000102515
ENSDART00000172796
mesoderm development LRP chaperone
chr19_+_5318358 0.53 ENSDART00000082133
si:dkeyp-113d7.1
chr9_-_52386733 0.51 ENSDART00000171721
death associated protein 1b
chr1_-_524433 0.50 ENSDART00000147610
si:ch73-41e3.7
chr15_-_4580763 0.50 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr19_-_808265 0.50 ENSDART00000082454
glycosylated lysosomal membrane protein
chr5_+_57210237 0.49 ENSDART00000167660
praja ring finger ubiquitin ligase 2
chr19_+_167612 0.49 ENSDART00000169574
TatD DNase domain containing 1
chr3_-_41535647 0.46 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
chr17_-_17764801 0.46 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr8_+_41229233 0.46 ENSDART00000131135
zgc:152830
chr3_+_34180835 0.46 ENSDART00000055252
translocase of inner mitochondrial membrane 29
chr23_-_44546124 0.45 ENSDART00000126779
ENSDART00000024082
proteasome subunit beta 6
chr4_-_965267 0.45 ENSDART00000093289
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr9_-_23747264 0.44 ENSDART00000141461
ENSDART00000010311
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr20_-_14665002 0.43 ENSDART00000152816
secernin 2
chr23_+_19670085 0.43 ENSDART00000031872
potassium channel tetramerization domain containing 6b
chr21_-_2958422 0.42 ENSDART00000174091
zgc:194215
chr18_-_1414760 0.41 ENSDART00000171881
peptidase D
chr24_+_42149453 0.41 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr2_-_32486080 0.40 ENSDART00000110821
tetratricopeptide repeat domain 19
chr23_+_19198244 0.40 ENSDART00000047015
coiled-coil domain containing 115
chr12_-_11649690 0.39 ENSDART00000149713
BTB (POZ) domain containing 16
chr4_-_20051141 0.39 ENSDART00000066963
ATPase H+ transporting V1 subunit F
chr13_+_13930263 0.38 ENSDART00000079154
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr7_-_46019756 0.37 ENSDART00000162583
zgc:162297
chr3_+_43086548 0.37 ENSDART00000163579
si:dkey-43p13.5
chr1_+_52462068 0.37 ENSDART00000124682
galactosidase, beta 1
chr3_+_39566999 0.37 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr12_-_9516981 0.36 ENSDART00000106285
si:ch211-207i20.3
chr2_+_24936766 0.35 ENSDART00000025962
glycogenin 1a
chr5_-_69804433 0.35 ENSDART00000028954
Rab interacting lysosomal protein-like 2
chr9_-_8296723 0.35 ENSDART00000139867
si:ch211-145c1.1
chr13_+_28512863 0.34 ENSDART00000043117
F-box and WD repeat domain containing 4
chr4_-_5247335 0.34 ENSDART00000050221
ATPase H+ transporting V1 subunit E1b
chr15_-_1031511 0.34 ENSDART00000153569
si:dkey-77f5.4
chr8_+_39767915 0.34 ENSDART00000017153
Hermansky-Pudlak syndrome 4
chr15_+_37545855 0.33 ENSDART00000099456
presenilin enhancer gamma secretase subunit
chr20_-_13140309 0.33 ENSDART00000020703
ENSDART00000188594
integrator complex subunit 7
chr10_-_309894 0.33 ENSDART00000163287

chr23_+_31912882 0.33 ENSDART00000140505
armadillo repeat containing 1, like
chr10_+_20070178 0.33 ENSDART00000027612
ENSDART00000145264
ENSDART00000172713
exportin 7
chr17_-_6535941 0.33 ENSDART00000109249
centromere protein O
chr19_+_619200 0.32 ENSDART00000050125
nucleoporin like 2
chr21_+_7298687 0.31 ENSDART00000187746

chr13_+_28512530 0.31 ENSDART00000188510
F-box and WD repeat domain containing 4
chr10_+_7636811 0.31 ENSDART00000160673
histidine triad nucleotide binding protein 1
chr22_+_38037530 0.31 ENSDART00000012212
COMM domain containing 2
chr12_+_4712215 0.30 ENSDART00000152134
KAT8 regulatory NSL complex subunit 1a
chr6_-_39198912 0.30 ENSDART00000077938
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr13_-_18122333 0.30 ENSDART00000128748
WASH complex subunit 2C
chr15_+_25635326 0.30 ENSDART00000135409
ENSDART00000162240
ENSDART00000052645
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr23_+_36340520 0.30 ENSDART00000011201
coatomer protein complex, subunit zeta 1
chr5_-_41645058 0.30 ENSDART00000051092
RIO kinase 2 (yeast)
chr5_-_1963498 0.30 ENSDART00000073462
ribosomal protein, large, P0
chr3_+_54553931 0.29 ENSDART00000029387
peter pan homolog (Drosophila)
chr9_+_54686686 0.29 ENSDART00000066198
RAB9A, member RAS oncogene family
chr11_-_44945636 0.29 ENSDART00000157658
origin recognition complex, subunit 2
chr10_+_26118122 0.29 ENSDART00000079207
tripartite motif containing 47
chr5_+_69622005 0.29 ENSDART00000167388
vacuolar protein sorting 33A
chr20_-_29683754 0.29 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
chr14_+_16765992 0.29 ENSDART00000140061
sequestosome 1
chr22_+_1431743 0.29 ENSDART00000182871
Danio rerio si:dkeyp-53d3.6 (si:dkeyp-53d3.6), mRNA.
chr19_+_7627070 0.29 ENSDART00000151078
ENSDART00000131324
pygopus homolog 2 (Drosophila)
chr15_-_28596507 0.28 ENSDART00000156800
si:ch211-225b7.5
chr14_+_39156 0.28 ENSDART00000082184
transmembrane protein 107
chr3_-_34180364 0.28 ENSDART00000151819
ENSDART00000003133
Yip1 domain family, member 2
chr11_-_35756468 0.28 ENSDART00000103076
ADP-ribosylation factor-like 8Bb
chr1_+_49673489 0.28 ENSDART00000135487
testis specific, 10
chr19_-_27334394 0.28 ENSDART00000052359
general transcription factor IIH, polypeptide 4
chr21_-_308852 0.28 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr8_-_2230128 0.28 ENSDART00000140427
si:dkeyp-117b11.2
chr23_-_22130778 0.28 ENSDART00000079212
polyhomeotic homolog 2a (Drosophila)
chr23_+_384850 0.28 ENSDART00000114000
zgc:101663
chr8_+_23213320 0.27 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr23_-_35066816 0.27 ENSDART00000168731
ENSDART00000163731

chr3_-_15859397 0.27 ENSDART00000135924
dehydrogenase/reductase (SDR family) member 7B
chr11_-_31276064 0.27 ENSDART00000141062
ENSDART00000004780
mannosidase, alpha, class 2B, member 1
chr21_-_4950610 0.27 ENSDART00000138518
si:ch73-29c22.1
chr3_+_16922226 0.26 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr4_+_17539134 0.26 ENSDART00000013313
integrin alpha FG-GAP repeat containing 2
chr23_-_19153378 0.26 ENSDART00000019045
ENSDART00000183681
emopamil binding protein (sterol isomerase)
chr12_+_47044707 0.26 ENSDART00000186506
zinc finger, RAN-binding domain containing 1a
chr10_+_43037064 0.26 ENSDART00000160159
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr22_-_5661789 0.26 ENSDART00000176242
coiled-coil domain containing 51
chr14_+_1240235 0.26 ENSDART00000127477
adenosine deaminase domain containing 1 (testis-specific)
chr4_+_17844013 0.26 ENSDART00000019165
apoptotic peptidase activating factor 1
chr8_+_50531709 0.26 ENSDART00000193352
phosphatidylethanolamine binding protein 4
chr10_+_41159241 0.25 ENSDART00000141657
annexin A4
chr21_-_45891262 0.25 ENSDART00000169816
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr18_+_14693682 0.25 ENSDART00000132249
URI1, prefoldin-like chaperone
chr15_+_6652396 0.25 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr18_+_31280984 0.24 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
differentially expressed in FDCP 8 homolog (mouse)
chr16_-_5143124 0.24 ENSDART00000131876
ENSDART00000060630
ttk protein kinase
chr22_+_29991834 0.24 ENSDART00000147728
si:dkey-286j15.3
chr3_+_23752150 0.24 ENSDART00000146636
homeobox B2a
chr6_+_59944488 0.24 ENSDART00000161158
nuclear fragile X mental retardation protein interacting protein 1
chr10_-_35149513 0.24 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr8_+_26410197 0.23 ENSDART00000145836
ENSDART00000053447
interferon-related developmental regulator 2
chr1_+_34496855 0.23 ENSDART00000012873
Kruppel-like factor 12a
chr1_+_42345532 0.23 ENSDART00000143871
catenin (cadherin-associated protein), alpha 2
chr2_+_20868286 0.23 ENSDART00000062591
odr-4 GPCR localization factor homolog
chr11_-_44163164 0.23 ENSDART00000047126
chloride channel, voltage-sensitive 4
chr2_-_53896300 0.23 ENSDART00000161221
calcyphosine-like a
chr5_-_13167097 0.23 ENSDART00000149700
ENSDART00000030213
mitogen-activated protein kinase 1
chr14_+_8456870 0.23 ENSDART00000007738
transmembrane and coiled-coil domains 6
chr25_-_23583101 0.23 ENSDART00000149107
ENSDART00000103704
ENSDART00000184903
nucleosome assembly protein 1-like 4a
chr9_+_30108641 0.23 ENSDART00000060174
jagunal homolog 1a
chr9_+_42066030 0.23 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr3_-_21106093 0.23 ENSDART00000156566
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr16_+_19029297 0.23 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr18_-_5103931 0.22 ENSDART00000188091
programmed cell death 10a
chr25_+_16098620 0.22 ENSDART00000142564
ENSDART00000165598
fatty acyl CoA reductase 1
chr14_-_17575764 0.22 ENSDART00000123145
ring finger protein 4
chr5_-_22130937 0.22 ENSDART00000138606
LAS1-like, ribosome biogenesis factor
chr4_-_73447058 0.22 ENSDART00000172042
si:ch73-120g24.4
chr13_-_18119696 0.22 ENSDART00000148125
WASH complex subunit 2C
chr10_-_29768556 0.22 ENSDART00000052787
vacuolar protein sorting 11
chr19_-_5103313 0.22 ENSDART00000037007
triosephosphate isomerase 1a
chr25_+_10547228 0.22 ENSDART00000067678
zgc:110339
chr7_-_41812355 0.22 ENSDART00000016105
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr14_+_33413980 0.21 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr2_-_193707 0.21 ENSDART00000187642
zinc finger protein 1014
chr7_-_41812015 0.21 ENSDART00000174058
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr1_+_47091468 0.21 ENSDART00000036783
crystallin, zeta (quinone reductase)-like 1
chr25_-_14424406 0.21 ENSDART00000073609
protein arginine methyltransferase 7
chr25_+_20715950 0.21 ENSDART00000180223
ERGIC and golgi 2
chr18_-_11729 0.21 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr12_-_30359498 0.21 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr4_+_17843717 0.21 ENSDART00000113507
apoptotic peptidase activating factor 1
chr14_+_22076596 0.21 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr16_+_4654333 0.21 ENSDART00000167665
si:ch1073-284b18.2
chr13_-_280827 0.21 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr13_-_280652 0.20 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr10_-_29744921 0.20 ENSDART00000088605
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_-_8566567 0.20 ENSDART00000114613
pentatricopeptide repeat domain 1
chr14_+_52571134 0.20 ENSDART00000166708
ribosomal protein L26
chr7_-_19923249 0.20 ENSDART00000078694
zgc:110591
chr24_-_26854032 0.20 ENSDART00000087991
fibronectin type III domain containing 3Bb
chr20_-_37813863 0.20 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr23_-_26784736 0.20 ENSDART00000024064
ENSDART00000131615
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr17_+_24809221 0.20 ENSDART00000082251
ENSDART00000147871
ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr2_-_44971551 0.20 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr20_-_40720458 0.20 ENSDART00000153151
ENSDART00000061261
ENSDART00000138569
connexin 43
chr21_-_28737320 0.20 ENSDART00000098696
ENSDART00000124826
ENSDART00000125652
neuregulin 2a
chr14_+_14836468 0.20 ENSDART00000166728
si:dkey-102m7.3
chr3_-_13461056 0.20 ENSDART00000137678
F-box and WD repeat domain containing 9
chr13_-_25842074 0.20 ENSDART00000015154
poly(A) polymerase gamma
chr17_+_44441042 0.20 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr17_+_37215820 0.19 ENSDART00000104009
solute carrier family 30 (zinc transporter), member 1b
chr6_-_28222592 0.19 ENSDART00000131126
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr18_-_29898351 0.19 ENSDART00000138533
ENSDART00000064076
C-x(9)-C motif containing 2
chr18_-_16924221 0.19 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr5_+_69950882 0.19 ENSDART00000097359
DnaJ (Hsp40) homolog, subfamily C , member 25
chr21_+_19330774 0.19 ENSDART00000109412
helicase, POLQ like
chr24_-_36270855 0.19 ENSDART00000154858
si:ch211-40k21.5
chr18_-_898870 0.19 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr23_+_20513104 0.19 ENSDART00000079591
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr19_+_3842891 0.19 ENSDART00000159043
LSM10, U7 small nuclear RNA associated
chr4_-_25836684 0.19 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr1_+_17695426 0.19 ENSDART00000103236
ankyrin repeat domain 37
chr20_-_6476705 0.18 ENSDART00000077095
trafficking protein particle complex 8
chr25_-_6223567 0.18 ENSDART00000067512
proteasome subunit alpha 4
chr24_-_7632187 0.18 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr24_-_16917086 0.18 ENSDART00000110715
carboxymethylenebutenolidase homolog (Pseudomonas)
chr10_-_17587832 0.18 ENSDART00000113101
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
chr16_+_35536075 0.18 ENSDART00000183618
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr2_+_33189582 0.18 ENSDART00000145588
ENSDART00000136330
ENSDART00000139295
ENSDART00000086340
ring finger protein 220a

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1905132 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2 1.2 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 1.1 GO:1901207 regulation of heart looping(GO:1901207)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.2 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.4 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.2 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.5 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.4 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.2 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.4 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.6 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 1.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.3 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0060343 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.9 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.0 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.1 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.0 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.0 0.0 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.7 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.3 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.0 GO:0070209 ASTRA complex(GO:0070209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034618 arginine binding(GO:0034618)
0.2 0.7 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.7 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.7 GO:0042562 hormone binding(GO:0042562)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling