ISMARA results: tfap2d

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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tfap2d

Z-value: 0.21

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Transcription factors associated with tfap2d

Gene Symbol	Gene ID	Gene Info
tfap2d NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000023272	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
tfap2d	dr11_v1_chr20_-_47731768_47731768	0.90	2.6e-07	Click!

Activity profile of tfap2d motif

Sorted Z-values of tfap2d motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr5_+_42388464 Show fit	0.57	ENSDART00000191596	BX548073.13 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr13_-_36579086 Show fit	0.46	ENSDART00000146671	lgals3a NCBI UniProt ZFIN ENSEMBL Google Show fit	lectin, galactoside binding soluble 3a
chr20_-_14925281 Show fit	0.46	ENSDART00000152641	dnm3a NCBI UniProt ZFIN ENSEMBL Google Show fit	dynamin 3a
chr22_-_188102 Show fit	0.44	ENSDART00000125391 ENSDART00000170463	CABZ01052268.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr10_-_322769 Show fit	0.38	ENSDART00000165244	akt2l NCBI UniProt ZFIN ENSEMBL Google Show fit	v-akt murine thymoma viral oncogene homolog 2, like
chr2_-_47681454 Show fit	0.26	ENSDART00000056882	cul3a NCBI UniProt ZFIN ENSEMBL Google Show fit	cullin 3a
chr8_+_50946379 Show fit	0.24	ENSDART00000139649	b2ml NCBI UniProt ZFIN ENSEMBL Google Show fit	beta-2-microglobulin, like
chr17_+_52822831 Show fit	0.21	ENSDART00000193368	meis2a NCBI UniProt ZFIN ENSEMBL Google Show fit	Meis homeobox 2a
chr14_+_52369262 Show fit	0.20	ENSDART00000169352 ENSDART00000157833	igfbp7 NCBI UniProt ZFIN ENSEMBL Google Show fit	insulin-like growth factor binding protein 7
chr12_-_19007834 Show fit	0.16	ENSDART00000153248	chadlb NCBI UniProt ZFIN ENSEMBL Google Show fit	chondroadherin-like b
chr5_+_58520266 Show fit	0.16	ENSDART00000108889	oafb NCBI UniProt ZFIN ENSEMBL Google Show fit	OAF homolog b (Drosophila)
chr14_-_21064199 Show fit	0.12	ENSDART00000172099	si:dkey-74k8.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-74k8.3
chr9_-_4511613 Show fit	0.09	ENSDART00000168921	kcnj3a NCBI UniProt ZFIN ENSEMBL Google Show fit	potassium inwardly-rectifying channel, subfamily J, member 3a
chr22_-_57177 Show fit	0.07	ENSDART00000163959	CABZ01085139.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr17_+_52823015 Show fit	0.04	ENSDART00000160507 ENSDART00000186979	meis2a NCBI UniProt ZFIN ENSEMBL Google Show fit	Meis homeobox 2a
chr17_-_19022990 Show fit	0.02	ENSDART00000154186	flrt2 NCBI UniProt ZFIN ENSEMBL Google Show fit	fibronectin leucine rich transmembrane protein 2
chr21_-_5856050 Show fit	0.02	ENSDART00000115367	CABZ01071020.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr10_-_373575 Show fit	0.02	ENSDART00000114487	DMPK NCBI UniProt ZFIN ENSEMBL Google Show fit	DM1 protein kinase
chr17_+_24718272 Show fit	0.01	ENSDART00000007271	mtfr1l NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial fission regulator 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of tfap2d

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0010332	response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0	0.5	GO:0098884	postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.5	GO:0098844	postsynaptic endocytic zone membrane(GO:0098844)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0019865	IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)