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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tcf7

Z-value: 0.30

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Transcription factors associated with tcf7

Gene Symbol Gene ID Gene Info
ENSDARG00000038672 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf7dr11_v1_chr21_+_45316330_45316330-0.312.1e-01Click!

Activity profile of tcf7 motif

Sorted Z-values of tcf7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_817479 0.84 ENSDART00000123487
zgc:153675
chr10_+_19569052 0.76 ENSDART00000058425

chr10_-_21542702 0.69 ENSDART00000146761
ENSDART00000134502
zgc:165539
chr3_-_26183699 0.63 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr5_-_28149767 0.62 ENSDART00000051515
zgc:110329
chr11_-_23687158 0.57 ENSDART00000189599
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr4_-_77114795 0.55 ENSDART00000144849

chr3_-_26190804 0.53 ENSDART00000136001
yippee-like 3
chr12_-_11349899 0.52 ENSDART00000079645
zgc:174164
chr5_-_23696926 0.51 ENSDART00000021462
ring finger protein 128a
chr9_-_12401871 0.51 ENSDART00000191901
nucleoporin 35
chr10_-_32660716 0.51 ENSDART00000063544
ENSDART00000141013
autophagy related 101
chr21_+_13387965 0.50 ENSDART00000134347
zgc:113162
chr15_-_35930070 0.49 ENSDART00000076229
insulin receptor substrate 1
chr5_-_56964547 0.48 ENSDART00000074400
TIA1 cytotoxic granule-associated RNA binding protein
chr7_-_24112484 0.47 ENSDART00000111923
ajuba LIM protein
chr20_-_23876291 0.47 ENSDART00000043316
katanin p60 (ATPase containing) subunit A 1
chr13_+_33268657 0.45 ENSDART00000002095
transmembrane protein 39B
chr21_-_18275226 0.43 ENSDART00000126672
ENSDART00000135239
bromodomain containing 3a
chr3_-_26184018 0.43 ENSDART00000191604
si:ch211-11k18.4
chr6_+_46309795 0.38 ENSDART00000154817
si:dkeyp-67f1.1
chr12_+_48340133 0.38 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr1_+_24376394 0.37 ENSDART00000102542
zgc:171517
chr1_-_52790724 0.36 ENSDART00000139577
ENSDART00000100937
protein associated with topoisomerase II homolog 1 (yeast)
chr8_-_1266181 0.36 ENSDART00000148654
ENSDART00000149924
cell division cycle 14B
chr5_+_43470544 0.36 ENSDART00000111587
Rho-related BTB domain containing 2a
chr4_+_16827390 0.35 ENSDART00000113344
kisspeptin 2
chr3_-_23513155 0.35 ENSDART00000170200

chr14_+_989733 0.34 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr20_+_28266892 0.34 ENSDART00000103330
ChaC, cation transport regulator homolog 1 (E. coli)
chr21_+_15709061 0.34 ENSDART00000065772
D-dopachrome tautomerase
chr2_+_21174998 0.33 ENSDART00000079518
DnaJ (Hsp40) homolog, subfamily C, member 1
chr3_-_29891456 0.33 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr18_+_38775277 0.32 ENSDART00000186129
family with sequence similarity 214, member A
chr10_+_4046448 0.31 ENSDART00000123086
ENSDART00000052268
phosphatidylinositol transfer protein, beta
chr22_+_21549419 0.31 ENSDART00000139411
phospholipid phosphatase 2b
chr3_-_29891218 0.31 ENSDART00000142118
solute carrier family 25, member 39
chr19_-_18135724 0.31 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr20_+_46040666 0.29 ENSDART00000060744
si:dkey-7c18.24
chr21_+_20901505 0.28 ENSDART00000132741
complement component 7b
chr17_+_47116500 0.27 ENSDART00000186627
si:dkeyp-47f9.4
chr3_+_15773991 0.27 ENSDART00000089923
zinc finger protein 652
chr12_+_13908418 0.26 ENSDART00000066367
FK506 binding protein 10b
chr4_-_14531687 0.26 ENSDART00000182093
ENSDART00000159447
plexin b2a
chr19_-_7033636 0.26 ENSDART00000122815
ENSDART00000123443
ENSDART00000124094
death-domain associated protein
chr3_+_41558682 0.26 ENSDART00000157023
caspase recruitment domain family, member 11
chr11_+_44226200 0.25 ENSDART00000191417
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr24_-_41267184 0.25 ENSDART00000063504
xylulokinase homolog (H. influenzae)
chr20_-_4031475 0.25 ENSDART00000112053
family with sequence similarity 89, member A
chr1_-_681116 0.24 ENSDART00000165894
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_+_20453874 0.24 ENSDART00000124545
ENSDART00000008402
squamous cell carcinoma antigen recognized by T cells 3
chr1_+_594736 0.23 ENSDART00000166731
junctional adhesion molecule 2a
chr23_-_27061072 0.22 ENSDART00000124482
zgc:66440
chr22_+_8753092 0.22 ENSDART00000140720
si:dkey-182g1.2
chr16_+_20871021 0.22 ENSDART00000006429
3-hydroxyisobutyrate dehydrogenase b
chr17_+_24597001 0.21 ENSDART00000191834
rearranged L-myc fusion
chr1_+_260039 0.20 ENSDART00000092584
ENSDART00000111806
centromere protein E
chr7_+_29890292 0.20 ENSDART00000170403
ENSDART00000168600
talin 2a
chr4_-_2525916 0.20 ENSDART00000134123
ENSDART00000132581
ENSDART00000019508
cysteine and glycine-rich protein 2
chr7_-_57509447 0.20 ENSDART00000051973
ENSDART00000147036
sirtuin 3
chr22_+_12161738 0.20 ENSDART00000168857
cyclin T2b
chr7_-_22632938 0.20 ENSDART00000159867
ENSDART00000165706
si:dkey-112a7.4
chr5_+_42124706 0.19 ENSDART00000020044
ENSDART00000156372
sedoheptulokinase
chr25_+_3294150 0.18 ENSDART00000030683
thymopoietin b
chr2_-_43739740 0.18 ENSDART00000113849
kinesin family member 5B, a
chr11_-_17755444 0.18 ENSDART00000154627
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr24_+_9696760 0.18 ENSDART00000140200
ENSDART00000187411
DNA topoisomerase II binding protein 1
chr4_-_3064101 0.18 ENSDART00000135701
pleckstrin homology domain containing, family A member 5
chr23_+_39963599 0.18 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr7_+_36898622 0.18 ENSDART00000190773
TOX high mobility group box family member 3
chr24_-_11908115 0.17 ENSDART00000184329
transmembrane 9 superfamily member 1
chr5_+_60590796 0.17 ENSDART00000159859
transmembrane protein 132E
chr2_-_22152797 0.17 ENSDART00000145188
cytochrome P450, family 7, subfamily A, polypeptide 1
chr5_-_29238889 0.17 ENSDART00000143098
si:dkey-61l1.4
chr2_-_44038698 0.17 ENSDART00000079582
ENSDART00000146804
kirre like nephrin family adhesion molecule 1b
chr16_+_25137483 0.17 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr1_-_41374117 0.16 ENSDART00000074777
huntingtin
chr13_+_50778187 0.16 ENSDART00000159597
deoxynucleotidyltransferase, terminal
chr15_-_23485752 0.16 ENSDART00000152706
NLR family member X1
chr12_+_27068525 0.16 ENSDART00000188634
Snf2-related CREBBP activator protein
chr9_+_33009284 0.16 ENSDART00000036926
VANGL planar cell polarity protein 1
chr10_+_29849497 0.16 ENSDART00000099994
ENSDART00000132212
heat shock protein 8
chr5_+_44064764 0.16 ENSDART00000143843
si:dkey-84j12.1
chr17_+_13664442 0.16 ENSDART00000171689
leucine rich repeat and fibronectin type III domain containing 5a
chr7_-_22632518 0.15 ENSDART00000161046
si:dkey-112a7.4
chr1_-_50293946 0.15 ENSDART00000053028
ENSDART00000125099
TBC1 domain containing kinase
chr17_+_3993772 0.15 ENSDART00000170822
ENSDART00000168613
ENSDART00000186174
thioredoxin-related transmembrane protein 4
chr24_+_80653 0.15 ENSDART00000158473
ENSDART00000129135
reversion-inducing-cysteine-rich protein with kazal motifs
chr3_-_33934788 0.14 ENSDART00000151411
general transcription factor IIF, polypeptide 1
chr24_-_5932982 0.14 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acyl-CoA binding domain containing 5a
chr23_+_1702624 0.14 ENSDART00000149357
Rab geranylgeranyltransferase, alpha subunit
chr9_+_46745348 0.14 ENSDART00000025256
insulin-like growth factor binding protein 2b
chr24_+_37799818 0.14 ENSDART00000131975
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr8_+_26859639 0.13 ENSDART00000133440
PR domain containing 2, with ZNF domain a
chr18_-_6534516 0.13 ENSDART00000009217
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr22_-_8455462 0.12 ENSDART00000185238

chr24_+_81527 0.12 ENSDART00000192139
reversion-inducing-cysteine-rich protein with kazal motifs
chr21_+_18274825 0.12 ENSDART00000144322
ENSDART00000147768
WD repeat domain 5
chr5_-_37117778 0.12 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr3_-_26978793 0.12 ENSDART00000155396
nucleotide binding protein 1 (MinD homolog, E. coli)
chr7_-_22632690 0.11 ENSDART00000165245
si:dkey-112a7.4
chr18_-_6534357 0.11 ENSDART00000192886
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr2_-_37043540 0.11 ENSDART00000131834
guanine nucleotide binding protein (G protein), gamma 7
chr4_-_2945306 0.11 ENSDART00000128934
ENSDART00000019518
AE binding protein 2
chr2_+_37110504 0.10 ENSDART00000132794
ENSDART00000042974
solute carrier family 1 (glutamate transporter), member 8b
chr7_+_20518218 0.10 ENSDART00000052916
zgc:103586
chr14_+_20941038 0.10 ENSDART00000182539
zgc:66433
chr20_+_4221978 0.10 ENSDART00000171898
interaction protein for cytohesin exchange factors 1
chr19_-_13774502 0.09 ENSDART00000159711
erythrocyte membrane protein band 4.1a
chr9_-_9228941 0.09 ENSDART00000121665
cystathionine-beta-synthase b
chr14_-_6943934 0.09 ENSDART00000126279
CDC-like kinase 4a
chr4_-_20511595 0.09 ENSDART00000185806
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr1_+_32341484 0.09 ENSDART00000137156
pseudouridine 5'-phosphatase
chr10_-_25817854 0.09 ENSDART00000147677
periostin, osteoblast specific factor a
chr9_-_1604601 0.08 ENSDART00000143130
alkylglycerone phosphate synthase
chr17_-_20897407 0.07 ENSDART00000149481
ankyrin 3b
chr16_+_1353894 0.07 ENSDART00000148426
cugbp, Elav-like family member 3b
chr22_+_26804197 0.07 ENSDART00000135688
si:dkey-44g23.2
chr8_+_35356944 0.07 ENSDART00000143243
si:dkeyp-14d3.1
chr10_+_29849977 0.07 ENSDART00000180242
heat shock protein 8
chr8_-_2153147 0.07 ENSDART00000124093
si:dkeyp-117b11.1
chr23_-_19977214 0.07 ENSDART00000054659
cyclin Q
chr8_+_17869225 0.07 ENSDART00000080079
solute carrier family 44, member 5b
chr25_+_4635355 0.06 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr3_-_1146497 0.06 ENSDART00000149061
si:ch73-211l13.2
chr12_+_34273240 0.06 ENSDART00000037904
suppressor of cytokine signaling 3b
chr24_+_11334733 0.06 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
chr17_-_20897250 0.06 ENSDART00000088106
ankyrin 3b
chr17_-_6514962 0.06 ENSDART00000163514
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr12_-_979789 0.05 ENSDART00000128188
diacylglycerol lipase, beta
chr10_-_25816558 0.05 ENSDART00000017240
periostin, osteoblast specific factor a
chr9_-_22232902 0.04 ENSDART00000101845
crystallin, gamma M2d5
chr18_-_48492951 0.04 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr9_+_13733468 0.04 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abl-interactor 2a
chr7_-_54677143 0.04 ENSDART00000163748
cyclin D1
chr12_+_24561832 0.04 ENSDART00000088159
neurexin 1a
chr16_+_7703693 0.04 ENSDART00000125111
ENSDART00000149769
ENSDART00000149752
ENSDART00000081407
CCR4-NOT transcription complex, subunit 10
chr13_-_9895564 0.04 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
chr4_-_1908179 0.03 ENSDART00000139586
anoctamin 6
chr9_-_11560110 0.03 ENSDART00000176941
crystallin, beta A2b
chr15_-_1484795 0.03 ENSDART00000129356
si:dkeyp-97b10.3
chr16_-_11859309 0.03 ENSDART00000145754
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr19_-_38830582 0.03 ENSDART00000189966
ENSDART00000183055
adhesion G protein-coupled receptor B2
chr9_-_35875051 0.03 ENSDART00000013432
DnaJ (Hsp40) homolog, subfamily C, member 28
chr4_+_40302769 0.03 ENSDART00000137892
zinc finger protein 993
chr21_+_10790680 0.03 ENSDART00000144460
zinc finger protein 532
chr3_+_58119571 0.03 ENSDART00000108979
si:ch211-256e16.4
chr5_-_41996414 0.03 ENSDART00000143573
nuclear receptor corepressor 1
chr6_-_35488180 0.03 ENSDART00000183258
regulator of G protein signaling 8
chr2_-_59376735 0.02 ENSDART00000193624
finTRIM family, member 38
chr8_-_4097722 0.02 ENSDART00000135006
cut-like homeobox 2b
chr17_-_21993620 0.02 ENSDART00000179905
ENSDART00000078873
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 3
chr4_-_67800414 0.02 ENSDART00000160213
si:ch211-66c13.1
chr9_+_19039608 0.02 ENSDART00000055866
charged multivesicular body protein 2Ba
chr18_-_48508585 0.02 ENSDART00000133364
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr5_-_42894068 0.02 ENSDART00000169606
chemokine (C-X-C motif) ligand 11, duplicate 1
chr23_+_27051919 0.02 ENSDART00000054237
prostaglandin E synthase 3a (cytosolic)
chr20_-_51917771 0.02 ENSDART00000147240
dual specificity phosphatase 10
chr24_+_26017094 0.02 ENSDART00000137851
transferrin receptor 1b
chr4_-_32192868 0.02 ENSDART00000164675

chr4_+_69375564 0.02 ENSDART00000150334
si:dkey-246j6.1
chr1_+_58424507 0.02 ENSDART00000114197
si:ch73-236c18.3
chr10_+_40660772 0.02 ENSDART00000148007
trace amine associated receptor 19l
chr2_-_59376399 0.01 ENSDART00000137134
finTRIM family, member 38
chr24_-_6546479 0.01 ENSDART00000160538
Rho GTPase activating protein 21a
chr5_-_16996482 0.01 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr10_+_45128375 0.01 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr4_-_2036620 0.01 ENSDART00000150490
si:dkey-97m3.1
chr12_+_46512881 0.01 ENSDART00000105454

chr5_+_19479200 0.01 ENSDART00000137703
aldehyde dehydrogenase 3 family, member B2
chr12_+_46462090 0.01 ENSDART00000130748

chr3_+_1689220 0.01 ENSDART00000183465

chr14_-_2358774 0.01 ENSDART00000164809
si:ch73-233f7.5
chr14_-_2036604 0.01 ENSDART00000192446

chr20_-_27225064 0.01 ENSDART00000153121
si:dkey-85n7.7
chr14_-_2193248 0.01 ENSDART00000128659
protocadherin 2 alpha b 10
chr15_-_17190540 0.01 ENSDART00000154801
integrin, alpha E, tandem duplicate 2
chr17_-_14591764 0.01 ENSDART00000174703
dishevelled associated activator of morphogenesis 1a
chr20_+_36234335 0.01 ENSDART00000193484
ENSDART00000181664
cornichon family AMPA receptor auxiliary protein 3
chr9_-_48864942 0.01 ENSDART00000113855
ENSDART00000189064
nitric oxide synthase trafficking
chr24_+_36636208 0.01 ENSDART00000139211
si:ch73-334d15.4
chr12_+_6465557 0.01 ENSDART00000066477
ENSDART00000122271
dickkopf WNT signaling pathway inhibitor 1b
chr4_+_34369818 0.01 ENSDART00000160548
si:ch211-246b8.1
chr7_-_18691637 0.00 ENSDART00000183715
si:ch211-119e14.9
chr4_-_30422325 0.00 ENSDART00000158444
zinc finger protein 1114
chr3_-_6281503 0.00 ENSDART00000184977

chr5_-_24231139 0.00 ENSDART00000143492
SUMO1/sentrin/SMT3 specific peptidase 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.3 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.3 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.5 GO:0006999 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.4 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.6 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.5 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis