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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tcf3a+tcf3b

Z-value: 0.99

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Transcription factors associated with tcf3a+tcf3b

Gene Symbol Gene ID Gene Info
ENSDARG00000005915 transcription factor 3a
ENSDARG00000099999 transcription factor 3b
ENSDARG00000112646 transcription factor 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf3bdr11_v1_chr22_-_20342260_203422600.391.1e-01Click!
tcf3adr11_v1_chr2_-_57379216_57379216-0.107.1e-01Click!

Activity profile of tcf3a+tcf3b motif

Sorted Z-values of tcf3a+tcf3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_58751504 3.80 ENSDART00000024185
zgc:56231
chr6_+_153146 3.20 ENSDART00000097468
zinc finger, GATA-like protein 1
chr19_+_14109348 2.39 ENSDART00000159015
zgc:175136
chr4_-_20177868 2.19 ENSDART00000003621
siaz-interacting nuclear protein
chr21_+_25777425 2.18 ENSDART00000021620
claudin d
chr19_-_27564458 2.17 ENSDART00000123155
si:dkeyp-46h3.6
chr21_+_5192016 2.00 ENSDART00000139288
si:dkey-121h17.7
chr10_-_8046764 1.98 ENSDART00000099031
zgc:136254
chr19_+_7001170 1.97 ENSDART00000110366
zinc finger and BTB domain containing 22b
chr13_-_21672131 1.87 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr22_-_10541372 1.77 ENSDART00000179708
si:dkey-42i9.4
chr22_-_10541712 1.76 ENSDART00000013933
si:dkey-42i9.4
chr1_-_18811517 1.72 ENSDART00000142026
si:dkey-167i21.2
chr19_-_27570333 1.69 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr1_+_59321629 1.69 ENSDART00000161981
poly(A)-specific ribonuclease (deadenylation nuclease)
chr19_-_4793263 1.68 ENSDART00000147510
ENSDART00000141336
ENSDART00000110551
ENSDART00000146684
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr5_-_68333081 1.65 ENSDART00000168786
linker histone H1M
chr2_+_6253246 1.65 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr21_-_43666420 1.63 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr2_-_17114852 1.61 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr16_-_42066523 1.59 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr8_-_7232413 1.59 ENSDART00000092426
glutamate receptor interacting protein 2a
chr1_-_34450622 1.58 ENSDART00000083736
LIM domain 7b
chr12_-_48168135 1.54 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr19_-_27564980 1.53 ENSDART00000171967
si:dkeyp-46h3.8
chr22_+_17828267 1.51 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr10_+_44699734 1.51 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scavenger receptor class B, member 1
chr21_-_19919020 1.49 ENSDART00000147396
protein phosphatase 1, regulatory subunit 3B
chr3_-_27880229 1.47 ENSDART00000151404
4-aminobutyrate aminotransferase
chr2_-_17115256 1.47 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr10_-_25217347 1.46 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr3_-_3413669 1.44 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
chr10_-_8053385 1.41 ENSDART00000142714
si:ch211-251f6.7
chr10_+_44700103 1.37 ENSDART00000165999
scavenger receptor class B, member 1
chr1_+_24387659 1.37 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr4_-_13614797 1.33 ENSDART00000138366
ENSDART00000165212
interferon regulatory factor 5
chr7_-_48263516 1.31 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr11_-_544187 1.30 ENSDART00000173161

chr21_-_30293224 1.30 ENSDART00000101051
stem-loop binding protein 2
chr11_-_45171139 1.28 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr20_-_20930926 1.24 ENSDART00000123909
BTB (POZ) domain containing 6b
chr2_-_50225411 1.23 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr23_+_384850 1.18 ENSDART00000114000
zgc:101663
chr6_-_15065376 1.17 ENSDART00000087797
transforming growth factor, beta receptor associated protein 1
chr8_+_12118097 1.17 ENSDART00000081819
endonuclease G
chr16_-_17713859 1.17 ENSDART00000149275
zgc:174935
chr9_-_356501 1.16 ENSDART00000168654
zgc:158320
chr24_+_14937205 1.15 ENSDART00000091735
docking protein 6
chr12_-_33357655 1.15 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr3_+_40576447 1.14 ENSDART00000083212
fascin actin-bundling protein 1a
chr8_-_18582922 1.13 ENSDART00000123917
transmembrane protein 47
chr2_+_30249977 1.12 ENSDART00000109160
ENSDART00000135171
transmembrane protein 70
chr13_+_36595618 1.11 ENSDART00000022684
cornichon family AMPA receptor auxiliary protein 1
chr15_+_6459847 1.11 ENSDART00000157250
ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr5_+_29851433 1.11 ENSDART00000143434
ubiquitin associated and SH3 domain containing Ba
chr13_+_11439486 1.07 ENSDART00000138312
zinc finger and BTB domain containing 18
chr8_-_1255321 1.07 ENSDART00000149605
cell division cycle 14B
chr1_-_156375 1.06 ENSDART00000160221
PCI domain containing 2
chr14_-_16810401 1.05 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_+_400487 1.05 ENSDART00000108872
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr10_+_1052591 1.03 ENSDART00000123405
unc-5 netrin receptor C
chr23_-_31647793 1.00 ENSDART00000145621
serum/glucocorticoid regulated kinase 1
chr20_+_48116476 0.99 ENSDART00000043938
translocation associated membrane protein 2
chr8_+_144154 0.98 ENSDART00000164099
sorting nexin 2
chr19_+_40069524 0.98 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr9_+_28232522 0.97 ENSDART00000031761
frizzled class receptor 5
chr5_-_53004052 0.97 ENSDART00000157978
mitochondrial ribosomal protein S30
chr21_+_5974590 0.96 ENSDART00000098499
deoxycytidine kinase
chr20_-_164300 0.96 ENSDART00000183354
si:ch211-241j12.3
chr5_-_69948099 0.96 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr14_-_24109580 0.96 ENSDART00000181415
cytoplasmic polyadenylation element binding protein 4a
chr13_-_9442942 0.95 ENSDART00000138833
glutaredoxin, cysteine rich 1
chr23_-_16692312 0.95 ENSDART00000046784
FK506 binding protein 1Ab
chr2_+_8261109 0.95 ENSDART00000024677
deleted in autism 1a
chr12_+_20693743 0.94 ENSDART00000153023
ENSDART00000153370
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr7_-_18881358 0.94 ENSDART00000021502
MLLT3, super elongation complex subunit
chr18_+_45573416 0.93 ENSDART00000132184
ENSDART00000145288
kinesin family member C3
chr24_-_32522587 0.93 ENSDART00000048968
ENSDART00000143781
zgc:56676
chr14_-_899170 0.93 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr13_+_2894536 0.93 ENSDART00000183678

chr6_-_1820606 0.93 ENSDART00000183228

chr7_-_19364813 0.92 ENSDART00000173977
netrin 4
chr3_+_40164129 0.92 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr12_+_20691310 0.92 ENSDART00000064335
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr16_+_27614989 0.91 ENSDART00000005625
GLI pathogenesis-related 2, like
chr14_+_21828993 0.91 ENSDART00000144367
C-terminal binding protein 1
chr5_-_63644938 0.91 ENSDART00000050865
surfeit gene 4, like
chr5_-_69944084 0.90 ENSDART00000188557
ENSDART00000127782
UDP glucuronosyltransferase 2 family, polypeptide A4
chr5_-_12743196 0.90 ENSDART00000188976
ENSDART00000137705
leucine-zipper-like transcription regulator 1
chr4_-_4834347 0.90 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr13_+_33462232 0.90 ENSDART00000177841
zgc:136302
chr22_-_17677947 0.88 ENSDART00000139911
tight junction protein 3
chr13_-_31938512 0.88 ENSDART00000026726
ENSDART00000182666
digestive organ expansion factor homolog
chr12_-_10512911 0.88 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr16_+_39159752 0.87 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr15_+_43906043 0.87 ENSDART00000010881
N-acetylated alpha-linked acidic dipeptidase 2
chr20_+_1316495 0.87 ENSDART00000064439
nucleoporin 43
chr5_+_62052538 0.87 ENSDART00000141574
si:dkey-35m8.1
chr1_-_47114310 0.87 ENSDART00000144899
ENSDART00000053157
SET domain containing 4
chr7_-_19369002 0.87 ENSDART00000165680
netrin 4
chr18_+_5454341 0.87 ENSDART00000192649
DTW domain containing 1
chr5_+_26212621 0.86 ENSDART00000134432
occludin b
chr20_-_20932760 0.86 ENSDART00000152415
ENSDART00000039907
BTB (POZ) domain containing 6b
chr16_+_54641230 0.85 ENSDART00000157641
ENSDART00000159540
F-box protein 43
chr8_+_36500308 0.85 ENSDART00000098701
solute carrier family 7, member 4
chr23_-_18057270 0.84 ENSDART00000173385
zgc:92287
chr11_+_13041341 0.84 ENSDART00000166126
ENSDART00000162074
ENSDART00000170889
basic transcription factor 3-like 4
chr18_+_45573251 0.84 ENSDART00000191309
kinesin family member C3
chr6_+_59991076 0.83 ENSDART00000163575

chr13_-_39254 0.82 ENSDART00000093222
general transcription factor IIA, 1-like
chr6_+_10338554 0.82 ENSDART00000186936
cordon-bleu WH2 repeat protein-like 1a
chr17_+_16090436 0.82 ENSDART00000136059
ENSDART00000138734
zinc finger protein 395a
chr20_+_1196386 0.82 ENSDART00000041192
LYR motif containing 2
chr14_+_591216 0.81 ENSDART00000169624
zgc:158257
chr8_+_36500061 0.81 ENSDART00000185840
solute carrier family 7, member 4
chr23_+_26079467 0.81 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr17_+_4368859 0.81 ENSDART00000055385
cardiolipin synthase 1
chr5_+_37744625 0.80 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr14_-_34605607 0.80 ENSDART00000191608
actin filament associated protein 1-like 1a
chr13_-_8692860 0.80 ENSDART00000058107
multiple coagulation factor deficiency 2
chr14_-_25930182 0.80 ENSDART00000018651
ENSDART00000147991
GTPase activating protein (SH3 domain) binding protein 1
chr12_-_25380028 0.80 ENSDART00000142674
zinc finger protein 36, C3H type-like 2
chr14_-_16754262 0.80 ENSDART00000001159
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr3_+_25990052 0.79 ENSDART00000007398
glycine C-acetyltransferase
chr10_+_10387328 0.79 ENSDART00000080904
sarcosine dehydrogenase
chr23_+_17522867 0.78 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr11_-_34219211 0.78 ENSDART00000098472
transmembrane protein 44
chr22_-_5171829 0.78 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr5_-_57624425 0.77 ENSDART00000167892
zgc:193711
chr1_+_12302073 0.77 ENSDART00000164045
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr6_-_14038804 0.77 ENSDART00000184606
ENSDART00000184609
ets variant 5b
chr5_-_11573490 0.77 ENSDART00000109577

chr14_-_33278084 0.76 ENSDART00000132850
START domain containing 14
chr5_+_34549845 0.76 ENSDART00000139317
allograft inflammatory factor 1-like
chr19_+_15441022 0.76 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr14_-_25928899 0.75 ENSDART00000143518
GTPase activating protein (SH3 domain) binding protein 1
chr14_-_33277743 0.75 ENSDART00000048130
START domain containing 14
chr2_+_11031360 0.75 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr17_+_1360192 0.74 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr15_+_1199407 0.74 ENSDART00000163827
major facilitator superfamily domain containing 1
chr19_-_425145 0.74 ENSDART00000164905
dihydrouridine synthase 3-like (S. cerevisiae)
chr10_+_2841205 0.74 ENSDART00000131505
ENSDART00000055869
YKT6 v-SNARE homolog (S. cerevisiae)
chr3_-_40275096 0.73 ENSDART00000141578
serine hydroxymethyltransferase 1 (soluble)
chr10_-_14929630 0.73 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
SMAD family member 2
chr14_-_24110062 0.72 ENSDART00000177062
cytoplasmic polyadenylation element binding protein 4a
chr21_-_44772738 0.72 ENSDART00000026178
kinesin family member 4
chr16_+_25259313 0.71 ENSDART00000058938
F-box protein 32
chr8_-_13735572 0.71 ENSDART00000139642
si:dkey-258f14.7
chr1_-_34450784 0.71 ENSDART00000140515
LIM domain 7b
chr1_-_524433 0.70 ENSDART00000147610
si:ch73-41e3.7
chr5_+_1515938 0.70 ENSDART00000054057
DDRGK domain containing 1
chr17_-_51818659 0.70 ENSDART00000111389
ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr1_+_30946231 0.69 ENSDART00000022841
methionyl aminopeptidase type 1D (mitochondrial)
chr12_+_24060894 0.68 ENSDART00000021298
ankyrin repeat and SOCS box containing 3
chr20_-_23254876 0.68 ENSDART00000141510
OCIA domain containing 1
chr12_-_10505986 0.68 ENSDART00000152672
zgc:152977
chr9_+_34148714 0.68 ENSDART00000078051
G protein-coupled receptor 161
chr3_+_60607241 0.67 ENSDART00000167512
major facilitator superfamily domain containing 11
chr21_+_13387965 0.67 ENSDART00000134347
zgc:113162
chr22_-_6420239 0.67 ENSDART00000148385
zgc:171699
chr20_+_14968031 0.67 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4
chr5_-_65121747 0.66 ENSDART00000165556
torsin family 2, member A
chr19_+_15485556 0.66 ENSDART00000079014
PDLIM1 interacting kinase 1 like
chr16_+_813780 0.66 ENSDART00000162474
ENSDART00000161774
iroquois homeobox 1a
chr19_-_48010490 0.66 ENSDART00000159938
zgc:158376
chr1_-_44048798 0.66 ENSDART00000073746
si:ch73-109d9.2
chr18_+_30441740 0.66 ENSDART00000189074
Gse1 coiled-coil protein
chr14_+_30340251 0.66 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr25_+_32390794 0.66 ENSDART00000012600
galactokinase 2
chr5_-_23696926 0.65 ENSDART00000021462
ring finger protein 128a
chr12_+_3262564 0.65 ENSDART00000184264
transmembrane protein 101
chr15_-_25099679 0.65 ENSDART00000154628
refilin B
chr14_+_38786298 0.65 ENSDART00000164440
si:ch211-195b11.3
chr11_+_24313931 0.64 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr8_-_34427364 0.64 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
GTPase activating protein and VPS9 domains 1
chr19_+_42660158 0.64 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr19_+_14454306 0.63 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr6_+_38896158 0.63 ENSDART00000029930
ENSDART00000131347
solute carrier family 48 (heme transporter), member 1b
chr5_+_36781732 0.63 ENSDART00000087191
MAP/microtubule affinity-regulating kinase 4a
chr19_-_30810328 0.63 ENSDART00000184875
MYCL proto-oncogene, bHLH transcription factor b
chr15_-_704408 0.63 ENSDART00000156200
ENSDART00000166404
ENSDART00000131040
zgc:174574
chr17_-_24884966 0.63 ENSDART00000136142
UDP-galactose-4-epimerase
chr19_+_28187480 0.62 ENSDART00000183825
iroquois homeobox 4b
chr23_-_31648026 0.62 ENSDART00000133569
serum/glucocorticoid regulated kinase 1
chr24_-_11905911 0.61 ENSDART00000033621
transmembrane 9 superfamily member 1
chr10_+_17345 0.61 ENSDART00000180325
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr1_+_13930625 0.61 ENSDART00000111026
nocturnin b
chr21_+_28747069 0.61 ENSDART00000014058
zgc:100829
chr25_+_3294150 0.61 ENSDART00000030683
thymopoietin b
chr6_-_11759860 0.61 ENSDART00000151296
si:ch211-162i14.1
chr11_-_44898129 0.61 ENSDART00000157615
eukaryotic translation initiation factor 4A3
chr21_-_34261677 0.60 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr5_+_28271412 0.60 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr19_-_12212692 0.60 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
zinc finger protein 706
chr1_+_12301913 0.60 ENSDART00000165733
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_-_13848296 0.60 ENSDART00000127109
folliculogenesis specific bHLH transcription factor
chr16_-_8132742 0.60 ENSDART00000104323
SNF related kinase a
chr23_+_39346774 0.60 ENSDART00000190985
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr23_+_43718865 0.60 ENSDART00000175192
anaphase promoting complex subunit 10
chr2_-_49854432 0.59 ENSDART00000180731
biliverdin reductase A

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf3a+tcf3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 0.6 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.5 1.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 1.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.4 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.1 GO:0090008 hypoblast development(GO:0090008)
0.3 1.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 1.5 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 1.4 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.3 1.3 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 3.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 0.8 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.2 1.7 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 1.7 GO:0002931 response to ischemia(GO:0002931)
0.2 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 1.1 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.2 0.7 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 0.9 GO:0060074 synapse maturation(GO:0060074)
0.2 0.7 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.2 3.2 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 1.3 GO:0006012 galactose metabolic process(GO:0006012)
0.2 1.3 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 0.7 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 0.5 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 0.8 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.2 0.8 GO:1901207 regulation of heart looping(GO:1901207)
0.2 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.5 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.2 2.2 GO:0001840 neural plate development(GO:0001840)
0.2 0.5 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.2 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.1 GO:2000405 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.6 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 1.5 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.7 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.7 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 2.5 GO:0008354 germ cell migration(GO:0008354)
0.1 0.4 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0070254 mucus secretion(GO:0070254)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 1.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 2.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.9 GO:0030104 water homeostasis(GO:0030104)
0.1 0.8 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.9 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.3 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.8 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 0.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.6 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 0.5 GO:0051031 tRNA transport(GO:0051031)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.5 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.8 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.4 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.1 0.7 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.4 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 1.1 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.5 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.1 1.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.4 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.7 GO:0008585 female gonad development(GO:0008585)
0.1 1.4 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.5 GO:0033687 osteoblast proliferation(GO:0033687)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.3 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 1.1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.6 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 3.1 GO:0048599 oocyte development(GO:0048599)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.6 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.6 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.8 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:0048532 anatomical structure arrangement(GO:0048532)
0.1 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 2.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.9 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.2 GO:0007620 mating(GO:0007618) copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.4 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.4 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0032367 intracellular cholesterol transport(GO:0032367) positive regulation of lipid transport(GO:0032370)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.4 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0032447 protein urmylation(GO:0032447)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.7 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.6 GO:0046849 bone remodeling(GO:0046849)
0.0 0.1 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0046824 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 2.6 GO:0006400 tRNA modification(GO:0006400)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 3.5 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.3 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0010459 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.3 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 1.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 2.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.5 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 5.2 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0048799 organ maturation(GO:0048799)
0.0 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0048794 swim bladder development(GO:0048794)
0.0 0.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.5 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0042478 regulation of eye photoreceptor cell development(GO:0042478)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of voltage-gated calcium channel activity(GO:1901387) positive regulation of cation channel activity(GO:2001259)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.0 GO:0008033 tRNA processing(GO:0008033)
0.0 0.6 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.0 GO:0051170 nuclear import(GO:0051170)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:1903307 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.6 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.3 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 1.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0060254 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.0 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0048823 nucleate erythrocyte differentiation(GO:0043363) nucleate erythrocyte development(GO:0048823)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 1.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.4 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.2 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.2 GO:0072380 TRC complex(GO:0072380)
0.1 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.5 GO:0000421 autophagosome membrane(GO:0000421)
0.1 3.0 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 1.4 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 1.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 3.1 GO:0005657 replication fork(GO:0005657)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0032797 SMN complex(GO:0032797)
0.1 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.3 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 5.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.7 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 5.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.0 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.0 0.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.8 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.0 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.6 3.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.6 2.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 1.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.5 1.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.4 1.5 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 1.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 0.7 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 1.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.8 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.2 0.8 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 1.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 3.2 GO:0032190 acrosin binding(GO:0032190)
0.2 0.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 0.5 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.2 2.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 1.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 1.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 1.6 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:1990715 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.1 2.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.5 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.5 GO:2001069 glycogen binding(GO:2001069)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 1.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 2.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.1 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.8 GO:0051117 ATPase binding(GO:0051117)
0.1 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 2.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 5.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 1.1 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.9 GO:0051287 NAD binding(GO:0051287)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.8 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.6 PID FOXO PATHWAY FoxO family signaling
0.1 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.0 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation