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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tbxta+tbxtb

Z-value: 1.07

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Transcription factors associated with tbxta+tbxtb

Gene Symbol Gene ID Gene Info
ENSDARG00000039806 T-box transcription factor Tb
ENSDARG00000101576 T-box transcription factor Ta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbxtbdr11_v1_chr13_+_4440869_4440869-0.663.1e-03Click!
tbxtadr11_v1_chr19_-_14191592_141915920.561.5e-02Click!

Activity profile of tbxta+tbxtb motif

Sorted Z-values of tbxta+tbxtb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_68333081 3.62 ENSDART00000168786
linker histone H1M
chr9_-_30385059 3.23 ENSDART00000060134
phosphatidylinositol glycan anchor biosynthesis, class A
chr13_-_36844945 3.21 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr11_-_25257045 3.06 ENSDART00000130477
snail family zinc finger 1a
chr11_-_25257595 2.96 ENSDART00000123567
snail family zinc finger 1a
chr7_+_51795667 2.77 ENSDART00000174201
ENSDART00000073839
solute carrier family 38, member 7
chr2_+_15069011 2.74 ENSDART00000145893
calponin 3, acidic b
chr2_+_9821757 2.35 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr12_-_4301234 2.32 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr18_+_16053455 2.24 ENSDART00000189163
ENSDART00000188269

chr20_-_38787047 2.13 ENSDART00000152913
ENSDART00000153430
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr7_+_35193832 2.00 ENSDART00000189002
zinc finger, DHHC-type containing 1
chr25_-_29363934 1.92 ENSDART00000166889
neuroplastin a
chr8_-_34427364 1.92 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
GTPase activating protein and VPS9 domains 1
chr14_+_28486213 1.87 ENSDART00000161852
stromal antigen 2b
chr10_+_1052591 1.86 ENSDART00000123405
unc-5 netrin receptor C
chr21_-_2185004 1.85 ENSDART00000163405
zgc:171220
chr12_-_33354409 1.82 ENSDART00000178515
solute carrier family 16 (monocarboxylate transporter), member 3
chr13_+_47821524 1.79 ENSDART00000109978
zinc finger CCCH-type containing 6
chr16_+_50741154 1.78 ENSDART00000101627
zgc:110372
chr10_+_26944418 1.76 ENSDART00000135493
FERM domain containing 8
chr20_+_9223514 1.75 ENSDART00000023293
potassium channel, subfamily K, member 5b
chr23_-_29812667 1.74 ENSDART00000006120
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr12_-_10508952 1.71 ENSDART00000152806
zgc:152977
chr19_-_11014641 1.71 ENSDART00000183745
tropomyosin 3
chr14_+_28518349 1.68 ENSDART00000159961
stromal antigen 2b
chr24_+_21174851 1.66 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr15_-_5580093 1.65 ENSDART00000143726
WD repeat domain 62
chr5_+_64277604 1.59 ENSDART00000111282
quiescin Q6 sulfhydryl oxidase 2
chr2_-_17392799 1.57 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_-_30385278 1.56 ENSDART00000183416
phosphatidylinositol glycan anchor biosynthesis, class A
chr5_+_25311309 1.55 ENSDART00000169638
wu:fa19b12
chr4_-_5019113 1.46 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr13_+_40437550 1.45 ENSDART00000057090
ENSDART00000167859
glutamic-oxaloacetic transaminase 1, soluble
chr3_-_36364903 1.43 ENSDART00000028883
guanine nucleotide binding protein (G protein), alpha 13b
chr21_-_5831413 1.38 ENSDART00000150914
wu:fj64h06
chr19_-_12965020 1.32 ENSDART00000128975
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr5_+_62374092 1.30 ENSDART00000082965

chr11_-_669558 1.30 ENSDART00000173450
peroxisome proliferator-activated receptor gamma
chr18_+_27571448 1.28 ENSDART00000147886
CD82 molecule b
chr3_-_26341959 1.26 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
chr11_+_13024002 1.26 ENSDART00000104113
basic transcription factor 3-like 4
chr9_+_4252839 1.25 ENSDART00000169740
kalirin RhoGEF kinase a
chr9_-_13871935 1.23 ENSDART00000146597
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr2_-_17393216 1.23 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_+_34151367 1.23 ENSDART00000143991
G protein-coupled receptor 161
chr11_-_669270 1.22 ENSDART00000172834
peroxisome proliferator-activated receptor gamma
chr8_+_47571211 1.21 ENSDART00000131460
phospholipase C, eta 2a
chr22_+_26600834 1.20 ENSDART00000157411
adenylate cyclase 9
chr12_-_10567188 1.19 ENSDART00000144283
myoferlin
chr23_-_32156278 1.15 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr1_-_31515746 1.15 ENSDART00000190886
centromere protein K
chr17_+_51517750 1.14 ENSDART00000180896
ENSDART00000193528
peroxidasin
chr21_-_26715270 1.13 ENSDART00000053794
barrier to autointegration factor 1
chr25_+_33256012 1.10 ENSDART00000059800
lactamase, beta
chr12_+_48972915 1.08 ENSDART00000170695
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b
chr20_-_14114078 1.05 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr6_-_16394528 1.05 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr24_-_31123365 1.03 ENSDART00000182947
transmembrane protein 56a
chr9_+_24065855 0.99 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr17_+_13763425 0.98 ENSDART00000105175
leucine rich repeat and fibronectin type III domain containing 5a
chr9_-_41323746 0.98 ENSDART00000140564
glutaminase b
chr11_+_18612166 0.97 ENSDART00000162694
nuclear receptor coactivator 3
chr12_+_19281189 0.93 ENSDART00000153428
trinucleotide repeat containing 6b
chr2_+_30531726 0.93 ENSDART00000146518
ankyrin repeat domain 33Bb
chr3_-_49514874 0.91 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr19_+_42061699 0.90 ENSDART00000125579
si:ch211-13c6.2
chr11_-_25853212 0.86 ENSDART00000145655
transmembrane protein 51b
chr1_-_23110740 0.86 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr5_+_28398449 0.85 ENSDART00000165292
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr22_+_20169352 0.85 ENSDART00000169055
ENSDART00000061617
high mobility group 20B
chr13_-_27388097 0.84 ENSDART00000187472
potassium voltage-gated channel, KQT-like subfamily, member 5a
chr7_+_48297842 0.82 ENSDART00000052123
solute carrier family 25, member 44 b
chr22_+_1868983 0.81 ENSDART00000160135
si:dkey-15h8.17
chr8_+_22277198 0.79 ENSDART00000005989
DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
chr5_-_66397688 0.78 ENSDART00000161483
huntingtin interacting protein 1 related b
chr7_+_66565930 0.78 ENSDART00000154597
transmembrane protein 176l.3b
chr10_-_4961923 0.77 ENSDART00000050177
ENSDART00000146066
sorting nexin family member 30
chr11_-_24532988 0.75 ENSDART00000067078
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr6_-_21726758 0.70 ENSDART00000083085
myotubularin related protein 14
chr22_-_3595439 0.70 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr12_+_27061720 0.69 ENSDART00000153426
Snf2-related CREBBP activator protein
chr18_-_16885362 0.67 ENSDART00000132778
switching B cell complex subunit SWAP70b
chr5_+_29652513 0.67 ENSDART00000035400
TSC complex subunit 1a
chr17_+_6535694 0.64 ENSDART00000191681
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr22_+_9523479 0.64 ENSDART00000189473
ENSDART00000143953
striatin interacting protein 1
chr11_-_40647190 0.64 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
family with sequence similarity 213, member B
chr25_+_459901 0.63 ENSDART00000154895
protogenin homolog b (Gallus gallus)
chr13_+_31757331 0.62 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr11_-_37880492 0.58 ENSDART00000102868
ethanolamine kinase 2
chr5_+_4436405 0.57 ENSDART00000167969

chr19_-_5372572 0.56 ENSDART00000151326
keratin 17
chr21_+_10866421 0.56 ENSDART00000137858
alpha-kinase 2
chr21_+_11923701 0.55 ENSDART00000109292
ubiquitin associated protein 2a
chr3_-_13955878 0.55 ENSDART00000166804
glutaryl-CoA dehydrogenase b
chr11_-_10850936 0.55 ENSDART00000091901
proteasome 26S subunit, non-ATPase 14
chr22_+_10678141 0.55 ENSDART00000193341
hyaluronoglucosaminidase 2b
chr3_-_5433392 0.54 ENSDART00000159308
tripartite motif containing 35-7
chr5_+_50913034 0.53 ENSDART00000149787
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr3_+_32842825 0.52 ENSDART00000122228
proline rich 14
chr2_+_24867534 0.52 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr1_+_35494837 0.52 ENSDART00000140724
GRB2-associated binding protein 1
chr5_+_50913357 0.49 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr13_+_2894536 0.49 ENSDART00000183678

chr6_-_35310224 0.46 ENSDART00000148997
nitric oxide synthase 1 (neuronal) adaptor protein a
chr5_-_68456987 0.46 ENSDART00000157810
ENSDART00000170819
eph receptor B4a
chr17_+_20237727 0.42 ENSDART00000180115
survival motor neuron domain containing 1
chr13_-_41482064 0.42 ENSDART00000188322
ENSDART00000164732
protocadherin-related 15a
chr3_-_32958505 0.42 ENSDART00000147374
ENSDART00000136919
caspase 6, apoptosis-related cysteine peptidase, like 1
chr13_-_51846224 0.41 ENSDART00000184663

chr1_-_50291266 0.41 ENSDART00000175142
ENSDART00000043309
TBC1 domain containing kinase
chr1_-_16507812 0.41 ENSDART00000169081
myotubularin related protein 7b
chr8_-_14609284 0.41 ENSDART00000146175
centrosomal protein 350
chr18_+_19419120 0.40 ENSDART00000025107
mitogen-activated protein kinase kinase 1
chr25_-_35046114 0.39 ENSDART00000185267
zgc:165555
chr20_+_22067337 0.38 ENSDART00000152636
clock circadian regulator a
chr14_-_30901602 0.36 ENSDART00000172925
si:ch211-126c2.4
chr9_+_12907574 0.35 ENSDART00000102348
si:dkey-230p4.1
chr16_+_15114645 0.33 ENSDART00000158483
MDM2 binding protein
chr22_-_34609528 0.32 ENSDART00000190781
ENSDART00000171712
telomeric repeat binding factor 2, interacting protein
chr8_-_24113575 0.31 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr13_+_40334727 0.29 ENSDART00000074950
solute carrier family 25 (mitochondrial iron transporter), member 28
chr15_-_34930727 0.29 ENSDART00000179723
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr24_-_41180149 0.28 ENSDART00000019975
activin A receptor type 2Ba
chr2_-_59247811 0.28 ENSDART00000141384
finTRIM family, member 32
chr12_+_10062953 0.27 ENSDART00000148689
solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr6_+_54248705 0.26 ENSDART00000162469
protein kinase C and casein kinase substrate in neurons 1b
chr3_+_28939759 0.25 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr4_+_76722754 0.25 ENSDART00000153867
membrane-spanning 4-domains, subfamily A, member 17A.3
chr3_-_1520657 0.24 ENSDART00000053201
polymerase (RNA) II (DNA directed) polypeptide F
chr15_+_863931 0.23 ENSDART00000154083
si:dkey-7i4.12
chr2_+_36121373 0.20 ENSDART00000187002

chr5_+_61998641 0.18 ENSDART00000137110
selenoprotein W, 1
chr19_+_14109348 0.16 ENSDART00000159015
zgc:175136
chr9_-_3958533 0.16 ENSDART00000129091
ubiquitin protein ligase E3 component n-recognin 3
chr18_-_44526940 0.14 ENSDART00000077125
amyloid beta (A4) precursor-like protein 2
chr2_+_36007449 0.14 ENSDART00000161837
laminin, gamma 2
chr21_-_19330333 0.14 ENSDART00000101462
mitochondrial ribosomal protein S18C
chr21_+_41468210 0.14 ENSDART00000192287
biorientation of chromosomes in cell division 1
chr12_-_4206869 0.13 ENSDART00000106572
si:dkey-32n7.9
chr12_-_43711918 0.13 ENSDART00000193110

chr24_-_20320480 0.12 ENSDART00000137366
mitogen-activated protein kinase kinase kinase 20
chr8_+_36142734 0.12 ENSDART00000159361
ENSDART00000161194
major histocompatibility complex class II integral membrane beta chain gene
chr18_+_23249519 0.11 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
myocyte enhancer factor 2aa
chr16_-_30878521 0.11 ENSDART00000141403
DENN/MADD domain containing 3b
chr21_+_33503835 0.11 ENSDART00000125658
clathrin interactor 1b
chr2_+_5521671 0.11 ENSDART00000099647
ENSDART00000138443
cytokine receptor family member B16
chr3_-_7464250 0.10 ENSDART00000159873
zinc finger protein 1001
chr5_-_33215261 0.10 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
chr13_+_45332203 0.09 ENSDART00000110466
si:ch211-168h21.3
chr20_-_8110672 0.09 ENSDART00000113993
si:ch211-232i5.1
chr9_-_22135576 0.09 ENSDART00000101902
crystallin, gamma M2d8
chr17_+_5915875 0.09 ENSDART00000184179
fibronectin type III domain containing 4b
chr9_-_1951144 0.08 ENSDART00000082355
homeobox D4a
chr23_+_7518294 0.08 ENSDART00000081536
HCK proto-oncogene, Src family tyrosine kinase
chr20_-_27330383 0.08 ENSDART00000153277
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr21_-_40938382 0.07 ENSDART00000008593
Yip1 domain family, member 5
chr24_-_33873451 0.06 ENSDART00000159840
acid-sensing (proton-gated) ion channel 1c
chr5_-_31856681 0.06 ENSDART00000187817
protein kinase N3
chr21_+_41468856 0.06 ENSDART00000161175
biorientation of chromosomes in cell division 1
chr24_+_26337623 0.05 ENSDART00000145637
myoneurin
chr3_+_6325895 0.05 ENSDART00000167386
ENSDART00000165000
zgc:136767
chr22_+_38767780 0.05 ENSDART00000149499
alkaline phosphatase, intestinal, tandem duplicate 1
chr22_-_3255341 0.04 ENSDART00000114232
G protein-coupled receptor 35, tandem duplicate 1
chr19_-_20148469 0.04 ENSDART00000134476
si:ch211-155k24.1
chr7_-_3860501 0.03 ENSDART00000191053
si:dkey-88n24.6
chr3_+_29510818 0.03 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
Rac family small GTPase 2
chr17_+_26965351 0.03 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr19_-_15335787 0.03 ENSDART00000187131
human immunodeficiency virus type I enhancer binding protein 3a
chr11_-_28086915 0.03 ENSDART00000161894
si:ch211-220m17.4
chr25_-_34281411 0.02 ENSDART00000189932
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_42478184 0.02 ENSDART00000089963
zgc:110286
chr22_+_2459591 0.02 ENSDART00000182602
si:ch73-92e7.4
chr11_+_13507053 0.02 ENSDART00000163160
ENSDART00000102548
si:dkey-13m1.5
chr13_+_12396316 0.02 ENSDART00000143557
ATPase phospholipid transporting 10D
chr15_-_41333064 0.01 ENSDART00000144678
si:dkey-121n8.7
chr8_-_44865832 0.01 ENSDART00000190298
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr7_+_25221757 0.01 ENSDART00000173551
exocyst complex component 6B
chr14_+_740032 0.01 ENSDART00000165014
klotho beta
chr2_+_49232559 0.01 ENSDART00000154285
ENSDART00000175147
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr3_+_13569806 0.01 ENSDART00000170105
si:ch73-106n3.2
chr5_+_61843752 0.01 ENSDART00000130940
Danio rerio interferon-induced protein with tetratricopeptide repeats 5 (LOC572297), mRNA.
chr20_+_14114258 0.00 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr9_-_3034064 0.00 ENSDART00000115138
ENSDART00000144046
Rap guanine nucleotide exchange factor (GEF) 4
chr9_-_31763246 0.00 ENSDART00000114742
si:dkey-250i3.3

Network of associatons between targets according to the STRING database.

First level regulatory network of tbxta+tbxtb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 1.7 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.4 1.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.4 1.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 6.0 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 3.6 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 4.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.0 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 2.3 GO:0008354 germ cell migration(GO:0008354)
0.1 1.7 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 1.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.7 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.5 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 1.0 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 3.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.5 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.9 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.1 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.7 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 2.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.6 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 1.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 2.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 1.1 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.3 1.7 GO:0031415 NatA complex(GO:0031415)
0.3 3.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 1.4 GO:0001650 fibrillar center(GO:0001650)
0.2 1.4 GO:0031526 brush border membrane(GO:0031526)
0.1 3.5 GO:0008278 cohesin complex(GO:0008278)
0.1 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 4.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 1.6 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.9 2.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.7 4.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.5 1.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.5 2.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 1.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.5 1.4 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.4 1.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 2.8 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.4 1.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 1.9 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 3.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 1.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.0 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 2.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.8 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 3.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 1.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)