ISMARA results: tbx15_tbx1_mgaa

Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation

Downloads

Results for tbx15_tbx1_mgaa_tbx4

Z-value: 0.84

Motif logo

Transcription factors associated with tbx15_tbx1_mgaa_tbx4

Gene Symbol	Gene ID	Gene Info
tbx15 NCBI UniProt	ENSDARG00000002582	T-box transcription factor 15
tbx1 NCBI UniProt	ENSDARG00000031891	T-box transcription factor 1
mgaa NCBI UniProt	ENSDARG00000078784	MAX dimerization protein MGA a
tbx4 NCBI UniProt	ENSDARG00000030058	T-box transcription factor 4
tbx4 NCBI UniProt	ENSDARG00000113067	T-box transcription factor 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
mgaa	dr11_v1_chr17_+_10570906_10570906	0.89	7.2e-07	Click!
tbx1	dr11_v1_chr5_+_15203421_15203421	0.22	3.8e-01	Click!
tbx4	dr11_v1_chr15_+_27387555_27387555	-0.20	4.2e-01	Click!
tbx15	dr11_v1_chr9_-_21067673_21067673	0.08	7.7e-01	Click!

Activity profile of tbx15_tbx1_mgaa_tbx4 motif

Sorted Z-values of tbx15_tbx1_mgaa_tbx4 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr21_-_3700334 Show fit	2.56	ENSDART00000137844	atp8b1 NCBI UniProt Show fit	ATPase phospholipid transporting 8B1
chr19_-_5332784 Show fit	1.82	ENSDART00000010373	krt1-19d NCBI UniProt Show fit	keratin, type 1, gene 19d
chr9_-_32912638 Show fit	1.64	ENSDART00000110582	fam160a2 NCBI UniProt Show fit	family with sequence similarity 160, member A2
chr20_+_21268795 Show fit	1.28	ENSDART00000090016	nudt14 NCBI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr22_+_26600834 Show fit	1.16	ENSDART00000157411	adcy9 NCBI UniProt Show fit	adenylate cyclase 9
chr1_-_52505279 Show fit	1.11	ENSDART00000052907	acy3.1 NCBI UniProt Show fit	aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr2_+_36007449 Show fit	1.06	ENSDART00000161837	lamc2 NCBI UniProt Show fit	laminin, gamma 2
chr22_-_3152357 Show fit	1.05	ENSDART00000170983	lmnb2 NCBI UniProt Show fit	lamin B2
chr12_-_5448993 Show fit	1.05	ENSDART00000181802	tbc1d12b NCBI UniProt Show fit	TBC1 domain family, member 12b
chr1_-_40341306 Show fit	1.00	ENSDART00000190649	maml3 NCBI UniProt Show fit	mastermind-like transcriptional coactivator 3

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx15_tbx1_mgaa_tbx4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	GO:0045332	phospholipid translocation(GO:0045332)
0.3	2.4	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	1.9	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	1.6	GO:0031497	chromatin assembly(GO:0031497)
0.1	1.4	GO:0008078	mesodermal cell migration(GO:0008078)
0.1	1.2	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.0	1.2	GO:0031101	fin regeneration(GO:0031101)
0.2	1.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	1.0	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.9	GO:0097198	histone H3-K36 trimethylation(GO:0097198)

Showing 1 to 10 of 125 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.2	GO:0005882	intermediate filament(GO:0005882)
0.0	2.8	GO:0005814	centriole(GO:0005814)
0.0	2.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	2.2	GO:0043296	apical junction complex(GO:0043296)
0.0	2.1	GO:0055037	recycling endosome(GO:0055037)
0.0	2.1	GO:0016607	nuclear speck(GO:0016607)
0.1	1.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.2	GO:0000786	nucleosome(GO:0000786)
0.0	1.2	GO:0016324	apical plasma membrane(GO:0016324)
0.0	1.0	GO:0016323	basolateral plasma membrane(GO:0016323)

Showing 1 to 10 of 47 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.8	GO:0000287	magnesium ion binding(GO:0000287)
0.3	1.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	1.4	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.1	1.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	1.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0	1.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	1.2	GO:0003724	RNA helicase activity(GO:0003724)
0.0	1.0	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.1	0.9	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.9	GO:0036002	pre-mRNA binding(GO:0036002)

Showing 1 to 10 of 77 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	1.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	1.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.9	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.8	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway

Showing 1 to 10 of 18 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.8	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions

Showing 1 to 10 of 24 entries

Results for tbx15_tbx1_mgaa_tbx4

Z-value: 0.84

Motif logo

Transcription factors associated with tbx15_tbx1_mgaa_tbx4

Activity-expression correlation:

Activity profile of tbx15_tbx1_mgaa_tbx4 motif

Sorted Z-values of tbx15_tbx1_mgaa_tbx4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx15_tbx1_mgaa_tbx4

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: