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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tal1

Z-value: 1.74

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Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr11_v1_chr22_+_16535575_165355750.831.7e-05Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_42467867 6.61 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr23_-_45319592 6.07 ENSDART00000189861
coiled-coil domain containing 171
chr5_+_338154 4.84 ENSDART00000191743
ring finger protein 170
chr15_-_551177 4.82 ENSDART00000066774
ENSDART00000154617
transgelin
chr17_-_39786222 4.65 ENSDART00000154515
Pim proto-oncogene, serine/threonine kinase, related 62
chr17_-_24838927 4.63 ENSDART00000123259

chr3_-_61592417 4.54 ENSDART00000155082
neuronal pentraxin 2a
chr25_-_18470695 4.17 ENSDART00000034377
carboxypeptidase A5
chr7_-_6470431 4.02 ENSDART00000081359
zgc:110425
chr12_-_656540 3.93 ENSDART00000172651
sulfotransferase family 2, cytosolic sulfotransferase 2
chr17_+_53156530 3.47 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr24_+_17269849 3.37 ENSDART00000017605
sperm associated antigen 6
chr3_+_58833306 3.37 ENSDART00000113223
immunoglobulin light 1 constant 3
chr7_+_44715224 3.36 ENSDART00000184630
si:dkey-56m19.5
chr2_+_49864219 3.29 ENSDART00000187744
ribosomal protein L37
chr11_+_25259058 3.26 ENSDART00000154109
tumor protein p53 inducible nuclear protein 2
chr7_+_24049776 3.23 ENSDART00000166559
embryonal Fyn-associated substrate
chr24_-_26310854 3.23 ENSDART00000080113
apolipoprotein Db
chr8_-_48704050 3.23 ENSDART00000163916
Pim proto-oncogene, serine/threonine kinase, related 182
chr6_+_9241121 3.22 ENSDART00000064989
Pim proto-oncogene, serine/threonine kinase, related 70
chr3_-_1190132 3.19 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr5_-_15692030 3.14 ENSDART00000099545

chr5_-_10007897 3.10 ENSDART00000109052
Danio rerio uncharacterized LOC799523 (LOC799523), mRNA.
chr19_+_27589201 3.06 ENSDART00000182060
si:dkeyp-46h3.1
chr20_+_25350435 2.99 ENSDART00000063034
family with sequence similarity 228, member A
chr17_-_681142 2.95 ENSDART00000165583
heme-binding protein soul3
chr14_-_36862745 2.94 ENSDART00000109293
ring finger protein 130
chr20_-_31075972 2.87 ENSDART00000122927
si:ch211-198b3.4
chr18_+_5547185 2.85 ENSDART00000193977
nicotinamide nucleotide transhydrogenase 2
chr8_+_47817454 2.83 ENSDART00000144825
Pim proto-oncogene, serine/threonine kinase, related 185
chr13_-_9525527 2.80 ENSDART00000190618

chr18_-_85294 2.78 ENSDART00000044387
GA binding protein transcription factor, beta subunit 1
chr10_+_4987766 2.73 ENSDART00000121959
si:ch73-234b20.5
chr18_+_54354 2.63 ENSDART00000097163
zgc:158482
chr7_-_50917255 2.63 ENSDART00000022918
ankyrin repeat domain 46b
chr3_-_32180796 2.60 ENSDART00000133191
ENSDART00000055308
PIH1 domain containing 1
chr24_+_35827766 2.55 ENSDART00000144700
si:dkeyp-7a3.1
chr23_+_578218 2.55 ENSDART00000055134
opioid growth factor receptor
chr12_+_18533198 2.55 ENSDART00000189729
meiosis specific with OB domains
chr19_+_43978814 2.52 ENSDART00000102314
naked cuticle homolog 3
chr11_-_306533 2.51 ENSDART00000173437
POC1 centriolar protein A
chr16_+_19014886 2.51 ENSDART00000079298
si:ch211-254p10.2
chr16_+_9495583 2.48 ENSDART00000150750
ENSDART00000150457
Pim proto-oncogene, serine/threonine kinase, related 208
chr24_-_26399623 2.46 ENSDART00000112317
zgc:194621
chr13_-_438705 2.44 ENSDART00000082142

chr3_-_32590164 2.40 ENSDART00000151151
tetraspanin 4b
chr22_-_164944 2.40 ENSDART00000145379
filamin binding LIM protein 1
chr22_+_20720808 2.32 ENSDART00000171321
si:dkey-211f22.5
chr1_+_22003173 2.28 ENSDART00000054388
dynein, axonemal, heavy chain 6
chr4_-_64703 2.27 ENSDART00000167851

chr14_+_9421510 2.27 ENSDART00000123652
high mobility group nucleosome binding domain 6
chr25_+_1732838 2.26 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr3_-_1232384 2.22 ENSDART00000053892
si:ch1073-314i13.4
chr9_-_23747264 2.17 ENSDART00000141461
ENSDART00000010311
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr5_-_34185115 2.16 ENSDART00000192771
fibrinogen C domain containing 1
chr1_+_22002649 2.16 ENSDART00000141317
dynein, axonemal, heavy chain 6
chr25_-_4482449 2.14 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr19_+_31904836 2.03 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr7_+_71683853 2.02 ENSDART00000163002
elastin microfibril interfacer 2b
chr13_+_31402067 2.02 ENSDART00000019202
tudor domain containing 9
chr1_-_59141715 2.01 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr1_+_57311901 2.01 ENSDART00000149397
mycbp associated protein
chr11_-_1392468 2.00 ENSDART00000004423
isoleucyl-tRNA synthetase
chr25_+_258883 1.97 ENSDART00000155256
zgc:92481
chr17_+_53311618 1.97 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr13_+_51981764 1.96 ENSDART00000160698
kelch domain containing 3
chr6_+_9893554 1.96 ENSDART00000064979
Pim proto-oncogene, serine/threonine kinase, related 74
chr2_-_16565690 1.94 ENSDART00000022549
ATPase Na+/K+ transporting subunit beta 3a
chr15_+_28368823 1.92 ENSDART00000142298
solute carrier family 43 (amino acid system L transporter), member 2a
chr12_+_18532866 1.91 ENSDART00000152126
ENSDART00000152443
ENSDART00000089589
meiosis specific with OB domains
chr3_+_54581987 1.89 ENSDART00000018071
eukaryotic translation initiation factor 3, subunit G
chr11_-_22372072 1.89 ENSDART00000065996
transmembrane protein 183A
chr21_-_551014 1.88 ENSDART00000099252
vimentin-related 1
chr1_+_55002583 1.88 ENSDART00000037250
si:ch211-196h16.12
chr2_-_42360329 1.88 ENSDART00000144274
ENSDART00000140863
si:dkey-7l6.3
chr16_+_30575901 1.87 ENSDART00000077231
melanocortin 2 receptor
chr23_+_26079467 1.86 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr15_-_34051457 1.84 ENSDART00000189764
si:dkey-30e9.7
chr14_-_32258759 1.82 ENSDART00000052949
fibroblast growth factor 13a
chr11_-_1509773 1.82 ENSDART00000050762
phosphatase and actin regulator 3b
chr8_-_48770163 1.81 ENSDART00000160959
Pim proto-oncogene, serine/threonine kinase, related 184
chr7_-_6346859 1.78 ENSDART00000172913
si:ch73-368j24.11
chr17_+_51940768 1.75 ENSDART00000053422
tubulin tyrosine ligase-like family, member 5
chr17_+_53439606 1.74 ENSDART00000154946
si:zfos-1714f5.3
chr5_+_28297254 1.74 ENSDART00000139862
ENSDART00000098635
vesicle-associated membrane protein 5
chr2_-_26620803 1.74 ENSDART00000003946
ENSDART00000126826
transmembrane protein 59
chr24_+_42132962 1.73 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr2_+_19633493 1.70 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr23_-_44848961 1.69 ENSDART00000136839
wu:fb72h05
chr17_+_25397070 1.68 ENSDART00000164254
zgc:154055
chr1_+_52560549 1.68 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr19_+_233143 1.67 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr21_+_2742823 1.63 ENSDART00000189004

chr1_-_52494122 1.63 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr15_-_4485828 1.63 ENSDART00000062868
transcription factor Dp-2
chr8_-_27687095 1.62 ENSDART00000086946
Moloney leukemia virus 10b, tandem duplicate 1
chr3_-_62380146 1.61 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr8_+_7144066 1.61 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr9_-_105135 1.61 ENSDART00000180126

chr16_-_41503925 1.59 ENSDART00000029492
CKLF-like MARVEL transmembrane domain containing 7
chr22_+_38310957 1.59 ENSDART00000040550
Tnf receptor-associated factor 5
chr20_+_33981946 1.59 ENSDART00000131775
si:dkey-51e6.1
chr24_-_7632187 1.58 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr14_-_28432699 1.58 ENSDART00000054062
NIMA-related kinase 12
chr5_+_41322783 1.57 ENSDART00000097546
AT rich interactive domain 3C (BRIGHT-like)
chr3_-_1388936 1.54 ENSDART00000171278
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr25_-_204019 1.54 ENSDART00000188440
ENSDART00000191735

chr14_+_17125428 1.54 ENSDART00000161489
solute carrier family 43, member 3b
chr3_-_53486169 1.51 ENSDART00000115243
heme-binding protein soul5
chr18_-_92046 1.50 ENSDART00000157709
GA binding protein transcription factor, beta subunit 1
chr20_-_284865 1.49 ENSDART00000104806
WNT1 inducible signaling pathway protein 3
chr20_+_54280549 1.48 ENSDART00000151048
ARP10 actin related protein 10 homolog
chr4_-_38033800 1.46 ENSDART00000159662
si:dkeyp-82b4.4
chr2_+_16160906 1.45 ENSDART00000135783
selenoprotein J
chr19_-_24555935 1.42 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr8_-_45759137 1.42 ENSDART00000123878
peptidylprolyl isomerase Aa (cyclophilin A)
chr20_-_49729446 1.42 ENSDART00000111089
filamin A interacting protein 1b
chr14_+_48964628 1.41 ENSDART00000105427
macrophage migration inhibitory factor
chr25_-_36369057 1.40 ENSDART00000064400
si:ch211-113a14.24
chr8_+_40210398 1.38 ENSDART00000167612
ring finger protein 34a
chr4_+_61171310 1.34 ENSDART00000141738
si:dkey-9p20.18
chr20_+_2460864 1.32 ENSDART00000131642
A kinase (PRKA) anchor protein 7
chr1_+_52563298 1.32 ENSDART00000142465
ATP-binding cassette, sub-family A (ABC1), member 1A
chr25_-_35153985 1.32 ENSDART00000154851
zgc:153405
chr4_-_1015896 1.31 ENSDART00000170292
family with sequence similarity 180 member A
chr14_-_17563773 1.31 ENSDART00000082667
fibroblast growth factor receptor like 1a
chr17_+_135590 1.30 ENSDART00000166339
kelch domain containing 2
chr25_+_36045072 1.29 ENSDART00000126326
RPGRIP1-like
chr9_+_51225345 1.29 ENSDART00000132896
fibroblast activation protein, alpha
chr23_-_40790196 1.28 ENSDART00000141216
si:dkey-194e6.2
chr2_+_17524278 1.28 ENSDART00000165633
Pim proto-oncogene, serine/threonine kinase, related 196
chr7_+_26029672 1.27 ENSDART00000101126
arachidonate 12-lipoxygenase
chr4_-_67589158 1.26 ENSDART00000184361

chr5_-_26181863 1.26 ENSDART00000098500
coiled-coil domain containing 125
chr5_-_5243079 1.25 ENSDART00000130576
ENSDART00000164377
multivesicular body subunit 12Ba
chr19_-_24555623 1.22 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_+_31479814 1.20 ENSDART00000148112
leucine rich repeat containing 9
chr7_-_27033080 1.19 ENSDART00000173516
nucleobindin 2a
chr5_-_417495 1.19 ENSDART00000180586
ENSDART00000189408
hook microtubule tethering protein 3
chr14_-_38809561 1.19 ENSDART00000159159
SIL1 nucleotide exchange factor
chr12_-_48960308 1.19 ENSDART00000176247

chr25_-_1333676 1.18 ENSDART00000183182
ENSDART00000188907
CLN6, transmembrane ER protein b
chr7_+_5964296 1.16 ENSDART00000173380
si:dkey-23a13.17
chr2_-_36350082 1.15 ENSDART00000193104

chr23_+_22656477 1.15 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr1_-_53468160 1.14 ENSDART00000143349
zgc:66455
chr6_-_51573975 1.14 ENSDART00000073865
retinoblastoma-like 1 (p107)
chr10_-_16470648 1.14 ENSDART00000149104
fibrillin 2a
chr4_-_63848305 1.13 ENSDART00000097308

chr7_-_6415991 1.13 ENSDART00000173349
Histone H3.2
chr21_-_43040780 1.13 ENSDART00000187037
janus kinase and microtubule interacting protein 2
chr7_+_25053331 1.12 ENSDART00000173998
si:dkey-23i12.7
chr7_+_69470142 1.12 ENSDART00000073861
GABA(A) receptor-associated protein b
chr2_+_20793982 1.12 ENSDART00000014785
proteoglycan 4a
chr10_-_25069155 1.10 ENSDART00000078226
ENSDART00000181941
melatonin receptor 1Bb
chr18_-_8398972 1.09 ENSDART00000136512
si:ch211-220f12.4
chr24_+_18714212 1.09 ENSDART00000171181
centrosome and spindle pole associated protein 1a
chr5_-_72376973 1.08 ENSDART00000164969

chr10_-_8295294 1.08 ENSDART00000075412
ENSDART00000163803
phospholipid phosphatase 1a
chr9_-_1499721 1.07 ENSDART00000062940
si:ch211-222f23.6
chr17_-_51938663 1.07 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr8_+_49149907 1.07 ENSDART00000138746
syntaphilin a
chr3_+_17537352 1.06 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr20_-_438646 1.05 ENSDART00000009196
UFM1-specific ligase 1
chr4_+_77943184 1.04 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2
chr10_-_8294965 1.04 ENSDART00000167380
phospholipid phosphatase 1a
chr4_-_5455506 1.04 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
chr17_+_53311243 1.04 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
ankyrin repeat and SOCS box containing 2b
chr4_-_64709908 1.01 ENSDART00000161032
si:dkey-9i5.2
chr5_+_58520266 1.01 ENSDART00000108889
OAF homolog b (Drosophila)
chr4_+_2267641 1.01 ENSDART00000165503
si:ch73-89b15.3
chr22_-_16494406 1.01 ENSDART00000062727
syntaxin 6
chr1_-_38816685 1.01 ENSDART00000075230
ankyrin repeat and SOCS box containing 5b
chr3_+_30500968 1.01 ENSDART00000103447
si:dkey-13n23.3
chr23_-_16682186 1.00 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr21_+_22840246 1.00 ENSDART00000151621
baculoviral IAP repeat containing 2
chr4_+_332709 1.00 ENSDART00000067486
tubby like protein 4a
chr5_-_30984010 0.99 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr25_+_36046287 0.98 ENSDART00000185324
RPGRIP1-like
chr1_+_41849152 0.98 ENSDART00000053685
spermine oxidase
chr9_-_356501 0.97 ENSDART00000168654
zgc:158320
chr25_-_18454016 0.96 ENSDART00000005877
carboxypeptidase A1 (pancreatic)
chr25_-_37501371 0.95 ENSDART00000160498

chr1_-_8980665 0.95 ENSDART00000148182
si:ch73-191k20.3
chr8_-_1051438 0.95 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr24_+_42074143 0.95 ENSDART00000170514
DNA topoisomerase I mitochondrial
chr11_-_8782871 0.94 ENSDART00000158546
si:ch211-51h4.2
chr25_-_3549321 0.93 ENSDART00000181214
ENSDART00000160600
haloacid dehalogenase like hydrolase domain containing 5
chr25_+_37340722 0.93 ENSDART00000137025
peptidase domain containing associated with muscle regeneration 1
chr19_+_31404686 0.91 ENSDART00000078459
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr7_-_18508815 0.91 ENSDART00000173539
regulator of G protein signaling 12a
chr4_-_52165969 0.90 ENSDART00000171130
si:dkeyp-44b5.4
chr8_-_54223316 0.89 ENSDART00000018054
thyrotropin-releasing hormone
chr25_-_173165 0.87 ENSDART00000193594

chr1_+_22851261 0.87 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr21_-_45073764 0.87 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr3_+_1209006 0.86 ENSDART00000158633
polymerase (DNA-directed), delta interacting protein 3
chr20_-_54377933 0.85 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr4_+_16787040 0.85 ENSDART00000039027
golgi transport 1Ba
chr4_-_20208166 0.85 ENSDART00000066891
gamma-secretase activating protein

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.7 2.9 GO:0006740 NADPH regeneration(GO:0006740)
0.6 3.2 GO:0090527 actin filament reorganization(GO:0090527)
0.6 3.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5 2.7 GO:0070254 mucus secretion(GO:0070254)
0.5 1.6 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.5 1.9 GO:0042755 eating behavior(GO:0042755)
0.4 1.9 GO:1901207 regulation of heart looping(GO:1901207)
0.4 2.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 6.2 GO:0016584 nucleosome positioning(GO:0016584)
0.3 1.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 2.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.3 1.3 GO:1902592 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.3 1.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 2.0 GO:0007141 male meiosis I(GO:0007141)
0.3 1.0 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.5 GO:0065001 specification of axis polarity(GO:0065001)
0.2 1.1 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 2.1 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 4.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 2.3 GO:0046548 retinal rod cell development(GO:0046548)
0.2 0.8 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.2 1.4 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 5.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.8 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.2 3.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 4.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 2.1 GO:0032098 regulation of appetite(GO:0032098)
0.2 1.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.5 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 2.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 3.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 3.9 GO:0051923 sulfation(GO:0051923)
0.1 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 1.9 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 4.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.4 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.1 1.6 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 1.3 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 3.2 GO:0007568 aging(GO:0007568)
0.1 0.4 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.0 GO:0001765 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 3.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.8 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.0 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 2.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.5 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 30.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.9 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.5 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 1.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 5.0 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 2.0 GO:0015807 L-amino acid transport(GO:0015807)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.3 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 1.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.9 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 1.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.2 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 2.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.5 GO:0014020 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 0.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.4 GO:0046849 bone remodeling(GO:0046849)
0.0 0.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.6 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.2 GO:0048278 vesicle docking(GO:0048278)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0097255 R2TP complex(GO:0097255)
0.3 1.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.3 1.6 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.2 0.9 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 2.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.7 GO:1990246 uniplex complex(GO:1990246)
0.1 3.6 GO:0043186 P granule(GO:0043186)
0.1 3.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.5 GO:0005869 dynactin complex(GO:0005869)
0.1 1.9 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 3.3 GO:0016605 PML body(GO:0016605)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 4.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 4.4 GO:0030286 dynein complex(GO:0030286)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.2 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 6.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 5.0 GO:0031201 SNARE complex(GO:0031201)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 5.5 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 2.4 GO:0005770 late endosome(GO:0005770)
0.0 2.0 GO:0005912 adherens junction(GO:0005912)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 2.6 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.7 2.9 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.7 2.1 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.6 3.0 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 2.4 GO:0031005 filamin binding(GO:0031005)
0.5 1.6 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.4 1.6 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.4 8.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 3.3 GO:0004985 opioid receptor activity(GO:0004985)
0.4 1.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 1.0 GO:0045545 syndecan binding(GO:0045545)
0.3 2.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 0.9 GO:0033149 FFAT motif binding(GO:0033149)
0.2 1.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 1.0 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 1.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 2.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 5.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 0.5 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.2 1.0 GO:0004104 cholinesterase activity(GO:0004104)
0.2 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.5 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 1.6 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.5 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 3.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 3.3 GO:0019843 rRNA binding(GO:0019843)
0.1 1.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 3.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 3.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 3.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 2.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0015923 mannosidase activity(GO:0015923)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 4.5 GO:0020037 heme binding(GO:0020037)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 17.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 6.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 5.2 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.9 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening