Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for stat1a+stat2-1_stat1b

Z-value: 0.67

Motif logo

Transcription factors associated with stat1a+stat2-1_stat1b

Gene Symbol Gene ID Gene Info
ENSDARG00000006266 signal transducer and activator of transcription 1a
ENSDARG00000031647 signal transducer and activator of transcription 2
ENSDARG00000076182 signal transducer and activator of transcription 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat1bdr11_v1_chr9_+_41218967_412189740.952.0e-09Click!
stat2dr11_v1_chr6_-_39160422_391604220.949.2e-09Click!
stat1adr11_v1_chr22_+_12798569_127985690.599.6e-03Click!

Activity profile of stat1a+stat2-1_stat1b motif

Sorted Z-values of stat1a+stat2-1_stat1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_17964525 3.76 ENSDART00000018948
cytokine inducible SH2-containing protein b
chr24_+_31361407 3.63 ENSDART00000162668
cAMP responsive element modulator b
chr6_-_40352215 3.34 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr9_+_40825065 2.69 ENSDART00000137673
si:dkey-95p16.2
chr14_+_33329420 2.39 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr13_-_37608441 2.26 ENSDART00000140230
zgc:123068
chr14_+_33329761 1.87 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr24_+_24923166 1.84 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr12_-_3133483 1.64 ENSDART00000015092
collagen, type I, alpha 1b
chr20_+_23440632 1.60 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr7_+_32369026 1.58 ENSDART00000169588
leucine-rich repeat containing G protein-coupled receptor 4
chr14_-_30747686 1.51 ENSDART00000008373
FOS-like antigen 1a
chr8_+_26522013 1.38 ENSDART00000046863
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr19_+_5418006 1.38 ENSDART00000132874
eukaryotic translation initiation factor 1B
chr22_+_7480465 1.28 ENSDART00000034545
zgc:92745
chr19_+_17385561 1.27 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
ribosomal protein L15
chr8_+_40573137 1.24 ENSDART00000184278
izumo sperm-egg fusion 1
chr22_-_16180467 1.19 ENSDART00000171331
ENSDART00000185607
vascular cell adhesion molecule 1b
chr9_+_52411530 1.19 ENSDART00000163684
NME/NM23 family member 8
chr21_+_45626136 1.18 ENSDART00000158742
interferon regulatory factor 1b
chr2_+_26288301 1.18 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr6_-_8311044 1.17 ENSDART00000129674
solute carrier family 44 (choline transporter), member 2
chr24_+_5208171 1.15 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
chr10_-_4375190 1.15 ENSDART00000016102

chr10_-_3332362 1.09 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr4_-_13567387 1.05 ENSDART00000132971
ENSDART00000102010
Mdm1 nuclear protein homolog (mouse)
chr8_-_47212686 1.00 ENSDART00000040370
Pim proto-oncogene, serine/threonine kinase, related 189
chr7_+_26029672 0.98 ENSDART00000101126
arachidonate 12-lipoxygenase
chr14_+_24241241 0.95 ENSDART00000022377
NK2 homeobox 5
chr21_-_27338639 0.94 ENSDART00000130632
hypoxia-inducible factor 1, alpha subunit, like 2
chr8_-_46060685 0.93 ENSDART00000121902
Pim proto-oncogene, serine/threonine kinase, related 188
chr1_-_46981134 0.90 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr15_-_32383529 0.89 ENSDART00000028349
complement component 4
chr14_-_21123551 0.88 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr21_+_26720803 0.87 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr20_-_35841570 0.85 ENSDART00000037855
tumor necrosis factor receptor superfamily, member 21
chr13_+_33117528 0.85 ENSDART00000085719
si:ch211-10a23.2
chr3_+_39853788 0.84 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr4_+_19127973 0.83 ENSDART00000136611
si:dkey-21o22.2
chr15_-_25083200 0.83 ENSDART00000156053
Pim proto-oncogene, serine/threonine kinase, related 191
chr15_-_25010400 0.83 ENSDART00000155236
si:ch211-198e20.10
chr21_+_8341774 0.82 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
proteasome subunit beta 7
chr20_+_52458765 0.82 ENSDART00000057980
tissue specific transplantation antigen P35B
chr21_+_35215810 0.81 ENSDART00000135256
ubiquitin domain containing 2
chr7_+_32369463 0.81 ENSDART00000180544
leucine-rich repeat containing G protein-coupled receptor 4
chr11_+_30321116 0.79 ENSDART00000187921
ENSDART00000127075
UDP glucuronosyltransferase 1 family, polypeptide B1
chr4_-_12323228 0.79 ENSDART00000081089
interleukin 17 receptor A1a
chr24_-_38197040 0.78 ENSDART00000137949
ENSDART00000105639
immunoglobulin light iota constant 1, s1
chr3_-_13461056 0.77 ENSDART00000137678
F-box and WD repeat domain containing 9
chr7_+_39706004 0.77 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr4_-_1497384 0.76 ENSDART00000093236
zmp:0000000711
chr11_-_27917730 0.76 ENSDART00000173219
eukaryotic translation initiation factor 4 gamma, 3a
chr24_+_16149514 0.75 ENSDART00000152087
si:dkey-118j18.2
chr16_+_40560622 0.73 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr24_+_16149251 0.72 ENSDART00000188289
si:dkey-118j18.2
chr15_-_25039083 0.72 ENSDART00000154409
Pim proto-oncogene, serine/threonine kinase, related 190
chr14_-_21123325 0.71 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr3_-_40933415 0.71 ENSDART00000055201
forkhead box K1
chr15_+_37412883 0.67 ENSDART00000156474
zinc finger and BTB domain containing 32
chr21_+_43404945 0.67 ENSDART00000142234
FERM domain containing 7
chr6_+_43015916 0.66 ENSDART00000064888
T cell leukemia translocation altered
chr3_-_13461361 0.65 ENSDART00000080807
F-box and WD repeat domain containing 9
chr16_-_12809873 0.65 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isochorismatase domain containing 2
chr16_-_36834505 0.64 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr21_+_20771082 0.64 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr13_-_37642890 0.64 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
chr16_-_41503925 0.64 ENSDART00000029492
CKLF-like MARVEL transmembrane domain containing 7
chr22_+_36914636 0.63 ENSDART00000150948
Pim proto-oncogene, serine/threonine kinase, related 205
chr21_-_30545121 0.63 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr23_-_39636195 0.62 ENSDART00000144439
von Willebrand factor A domain containing 1
chr19_+_712127 0.61 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
formin homology 2 domain containing 3a
chr18_-_16801033 0.60 ENSDART00000100100
adrenomedullin b
chr3_-_44059902 0.60 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr5_-_25582721 0.60 ENSDART00000123986
annexin A1a
chr18_+_10820430 0.60 ENSDART00000161990
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr5_-_25583125 0.60 ENSDART00000031665
ENSDART00000145353
annexin A1a
chr9_+_41218967 0.59 ENSDART00000000280
ENSDART00000145674
signal transducer and activator of transcription 1b
chr13_+_6092135 0.59 ENSDART00000162738
family with sequence similarity 120B
chr6_-_8498908 0.59 ENSDART00000149222
peptidoglycan recognition protein 2
chr5_+_13359146 0.58 ENSDART00000179839
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr19_+_43359075 0.58 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr4_-_18436899 0.57 ENSDART00000141671
suppressor of cytokine signaling 2
chr24_+_13635108 0.57 ENSDART00000183008
transient receptor potential cation channel, subfamily A, member 1b
chr1_+_10129099 0.57 ENSDART00000187740
RNA binding motif protein 46
chr12_+_19036380 0.56 ENSDART00000153086
ENSDART00000181060
potassium channel tetramerization domain containing 17
chr8_+_19548985 0.56 ENSDART00000123104
notch 2
chr1_-_2334254 0.56 ENSDART00000144500
si:ch211-235f1.3
chr8_-_43120844 0.55 ENSDART00000193242
coiled-coil domain containing 92
chr18_+_3332999 0.55 ENSDART00000160857
glycerophosphodiester phosphodiesterase domain containing 4a
chr18_-_14860435 0.55 ENSDART00000018502
mitogen-activated protein kinase 12a
chr21_-_20932603 0.53 ENSDART00000138155
ENSDART00000079709
complement component 6
chr16_+_54513267 0.52 ENSDART00000161923

chr9_-_6372535 0.52 ENSDART00000149189
esophageal cancer related gene 4a
chr18_+_30567945 0.51 ENSDART00000078894
interferon regulatory factor 8
chr25_-_4530085 0.51 ENSDART00000144907
p53-induced death domain protein 1
chr4_+_76735113 0.51 ENSDART00000075602
membrane-spanning 4-domains, subfamily A, member 17A.6
chr24_-_21674950 0.51 ENSDART00000123216
ENSDART00000046211
ligand of numb-protein X 2a
chr10_-_11012000 0.51 ENSDART00000132995
adenylate kinase 3
chr9_-_7652792 0.50 ENSDART00000137957
DnaJ (Hsp40) homolog, subfamily B, member 2
chr10_-_27223827 0.50 ENSDART00000185138
autism susceptibility candidate 2a
chr22_+_20427170 0.50 ENSDART00000136744
forkhead box Q2
chr6_-_35106425 0.50 ENSDART00000165139
nitric oxide synthase 1 (neuronal) adaptor protein a
chr15_-_32383340 0.49 ENSDART00000185632
complement component 4
chr14_-_36799280 0.49 ENSDART00000168615
ring finger protein 130
chr24_+_9590188 0.49 ENSDART00000137092
si:dkey-96n2.1
chr1_-_53504603 0.49 ENSDART00000162025
ENSDART00000100788
copper metabolism (Murr1) domain containing 1
chr15_+_6661343 0.48 ENSDART00000160136
NOP53 ribosome biogenesis factor
chr13_-_37631092 0.48 ENSDART00000108855
si:dkey-188i13.7
chr20_-_23440955 0.47 ENSDART00000153386
solute carrier family 10, member 4
chr12_+_7491690 0.47 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr4_-_779796 0.47 ENSDART00000128743
transmembrane protein 214
chr23_-_40792128 0.46 ENSDART00000145360
si:dkey-194e6.2
chr5_-_42883761 0.46 ENSDART00000167374

chr17_+_10318071 0.46 ENSDART00000161844
forkhead box A1
chr9_-_23922011 0.45 ENSDART00000145734
collagen, type VI, alpha 3
chr9_-_32813177 0.45 ENSDART00000012694
myxovirus (influenza virus) resistance C
chr2_+_22659787 0.45 ENSDART00000043956
zgc:161973
chr24_+_13635387 0.45 ENSDART00000105997
transient receptor potential cation channel, subfamily A, member 1b
chr1_-_9195629 0.45 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr7_-_28696556 0.45 ENSDART00000148822
adhesion G protein-coupled receptor G1
chr6_-_12456077 0.44 ENSDART00000190107
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr25_+_6186823 0.44 ENSDART00000153526
ornithine decarboxylase antizyme 2a
chr19_+_7759354 0.44 ENSDART00000151400
ubiquitin associated protein 2-like
chr3_-_7524363 0.42 ENSDART00000162970
zinc finger protein 1001
chr1_-_10071422 0.41 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr5_+_32009956 0.41 ENSDART00000188482
suppressor of cancer cell invasion
chr20_-_38446891 0.41 ENSDART00000192013
inositol-trisphosphate 3-kinase B
chr14_+_6159162 0.41 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr13_-_49819027 0.40 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr15_+_23550890 0.39 ENSDART00000009796
ENSDART00000152720
si:dkey-31m14.7
chr4_+_359970 0.38 ENSDART00000139832
transmembrane protein 181
chr21_-_22715297 0.37 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr23_-_40776046 0.36 ENSDART00000136230
si:dkeyp-27c8.1
chr16_+_30575901 0.36 ENSDART00000077231
melanocortin 2 receptor
chr15_-_35246742 0.36 ENSDART00000131479
mitochondrial fission factor
chr15_-_30832897 0.36 ENSDART00000152330
musashi RNA-binding protein 2b
chr7_+_52766211 0.35 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr24_-_22702017 0.35 ENSDART00000179403
catenin (cadherin-associated protein), delta 2a
chr15_-_31067589 0.34 ENSDART00000060157
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 3
chr9_-_54304684 0.34 ENSDART00000109512
interleukin 13
chr14_+_11457500 0.33 ENSDART00000169202
si:ch211-153b23.5
chr1_-_49225890 0.33 ENSDART00000111598
chemokine (C-X-C motif) ligand 18b
chr9_+_29585943 0.33 ENSDART00000185989
ENSDART00000115290
mcf.2 cell line derived transforming sequence-like b
chr16_-_29458806 0.32 ENSDART00000047931
leucine rich repeat and Ig domain containing 4b
chr15_-_3282220 0.32 ENSDART00000092942
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr11_-_22303678 0.32 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr4_-_9810999 0.32 ENSDART00000146858
si:dkeyp-27e10.3
chr6_+_18321627 0.31 ENSDART00000183107
ENSDART00000189715
caspase recruitment domain family, member 14
chr12_-_3252263 0.31 ENSDART00000170632
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b
chr16_-_36099492 0.31 ENSDART00000180905

chr3_+_24511959 0.30 ENSDART00000133898
dynein, axonemal, light chain 4a
chr20_+_53521648 0.30 ENSDART00000139794
p21 protein (Cdc42/Rac)-activated kinase 6b
chr19_-_26235219 0.30 ENSDART00000104008
dystrobrevin binding protein 1b
chr16_-_21668082 0.30 ENSDART00000088513
guanine nucleotide binding protein-like 1
chrM_+_4993 0.29 ENSDART00000093600
NADH dehydrogenase 2, mitochondrial
chr23_-_19682971 0.29 ENSDART00000048891
zgc:193598
chr2_-_10098191 0.29 ENSDART00000138081
B-cell CLL/lymphoma 6a, genome duplicate b
chr17_-_7861219 0.29 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr1_-_7582859 0.28 ENSDART00000110696
myxovirus (influenza) resistance B
chr17_+_6563307 0.28 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr1_-_54997746 0.28 ENSDART00000152666
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr7_+_41313568 0.28 ENSDART00000016660
zgc:165532
chr14_+_6159356 0.28 ENSDART00000157730
Bernardinelli-Seip congenital lipodystrophy 2, like
chr17_-_31344400 0.28 ENSDART00000154013
bromo adjacent homology domain containing 1
chr2_+_4402765 0.27 ENSDART00000159525
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr16_-_45398408 0.27 ENSDART00000004052
ral guanine nucleotide dissociation stimulator-like 2
chr23_+_7379728 0.27 ENSDART00000012194
GATA binding protein 5
chr19_-_35596207 0.27 ENSDART00000136811
collagen, type VIII, alpha 2
chr21_+_1568044 0.26 ENSDART00000193570
ENSDART00000151601
RAB27B, member RAS oncogene family
chr11_+_36777613 0.26 ENSDART00000065644
ENSDART00000158151
parapinopsin b
chr2_-_25140022 0.26 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr9_+_6934491 0.25 ENSDART00000114323
major facilitator superfamily domain containing 9
chr1_-_46343999 0.25 ENSDART00000145117
ENSDART00000193233
ATPase phospholipid transporting 11A
chr2_+_38261748 0.25 ENSDART00000076478
dehydrogenase/reductase (SDR family) member 1
chr7_+_48319916 0.25 ENSDART00000052122
cellular retinoic acid binding protein 1b
chr20_-_25412181 0.25 ENSDART00000062780
intersectin 2a
chr7_-_5191797 0.25 ENSDART00000172955
si:ch73-223f5.1
chr20_-_47188966 0.25 ENSDART00000152965
si:dkeyp-104f11.9
chr2_+_4207209 0.24 ENSDART00000157903
ENSDART00000166476
GATA binding protein 6
chr5_+_25072894 0.24 ENSDART00000012268
mitochondrial ribosomal protein L41
chr17_-_26604946 0.24 ENSDART00000087062
family with sequence similarity 149, member B1
chr16_-_1502699 0.24 ENSDART00000187189
single-minded family bHLH transcription factor 1a
chr10_+_22134606 0.24 ENSDART00000155228
si:dkey-4c2.11
chr4_+_76575585 0.24 ENSDART00000131588
membrane-spanning 4-domains, subfamily A, member 17A.11
chr6_+_11989537 0.24 ENSDART00000190817
bromodomain adjacent to zinc finger domain, 2Ba
chr9_-_23922778 0.24 ENSDART00000135769
collagen, type VI, alpha 3
chr21_-_20840714 0.23 ENSDART00000144861
ENSDART00000139430
complement component 6
chr1_+_30083578 0.23 ENSDART00000101779
ENSDART00000143639
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr6_-_8498676 0.23 ENSDART00000148627
peptidoglycan recognition protein 2
chr20_-_39273987 0.23 ENSDART00000127173
clusterin
chr20_+_25552057 0.23 ENSDART00000102913
cytochrome P450, family 2, subfamily V, polypeptide 1
chr5_+_1911814 0.23 ENSDART00000172233
si:ch73-55i23.1
chr7_+_41314862 0.23 ENSDART00000185198
zgc:165532
chr14_-_38828057 0.23 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr6_-_40286633 0.22 ENSDART00000033844
collagen, type VII, alpha 1
chr22_-_834106 0.22 ENSDART00000105873
cryptochrome circadian clock 4
chr19_+_10587307 0.22 ENSDART00000131225
si:dkey-211g8.4
chr11_+_25328199 0.22 ENSDART00000141478
ENSDART00000112209
family with sequence similarity 83, member D
chr7_-_28658143 0.22 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr22_+_26263290 0.21 ENSDART00000184840

Network of associatons between targets according to the STRING database.

First level regulatory network of stat1a+stat2-1_stat1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.3 1.0 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.3 1.0 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.3 1.2 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.3 1.2 GO:0015871 choline transport(GO:0015871)
0.3 0.9 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.3 0.8 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 1.2 GO:0045624 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 0.5 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.2 0.5 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 0.6 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 1.0 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 1.2 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.3 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.5 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.0 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.9 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 1.4 GO:0035036 sperm-egg recognition(GO:0035036)
0.1 0.3 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.3 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.3 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:0016038 absorption of visible light(GO:0016038)
0.1 3.3 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.4 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.6 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.3 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.2 GO:0060923 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 3.1 GO:0006956 complement activation(GO:0006956)
0.0 0.5 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.7 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.4 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0002526 acute inflammatory response(GO:0002526) acute-phase response(GO:0006953)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.4 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0002834 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0006959 humoral immune response(GO:0006959)
0.0 0.2 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 1.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0060975 cardioblast migration(GO:0003260) cardioblast migration to the midline involved in heart field formation(GO:0060975)
0.0 0.3 GO:0050795 regulation of behavior(GO:0050795)
0.0 0.1 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 4.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 3.5 GO:0005930 axoneme(GO:0005930)
0.0 0.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.4 1.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 0.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 1.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 2.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.1 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 1.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0047690 aspartyltransferase activity(GO:0047690)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.7 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport