ISMARA results: spi1a+spi1b

Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation

Downloads

Results for spi1a+spi1b

Z-value: 3.26

Motif logo

Transcription factors associated with spi1a+spi1b

Gene Symbol	Gene ID	Gene Info
spi1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000000767	Spi-1 proto-oncogene b
spi1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000067797	Spi-1 proto-oncogene a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
spi1b	dr11_v1_chr7_-_32659048_32659048	-0.84	1.3e-05	Click!
spi1a	dr11_v1_chr25_+_35553542_35553542	-0.77	1.8e-04	Click!

Activity profile of spi1a+spi1b motif

Sorted Z-values of spi1a+spi1b motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_+_12435975 Show fit	11.38	ENSDART00000168011	tmprss4a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protease, serine 4a
chr15_+_12436220 Show fit	11.25	ENSDART00000169894	tmprss4a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protease, serine 4a
chr18_+_15937610 Show fit	8.31	ENSDART00000061134 ENSDART00000154505	itpr2 NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol 1,4,5-trisphosphate receptor, type 2
chr7_-_26603743 Show fit	8.19	ENSDART00000099003	plscr3b NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipid scramblase 3b
chr16_-_24832038 Show fit	8.05	ENSDART00000153731	si:dkey-79d12.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-79d12.5
chr12_-_17686404 Show fit	7.47	ENSDART00000079065	ccz1 NCBI UniProt ZFIN ENSEMBL Google Show fit	CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr8_+_52442622 Show fit	6.96	ENSDART00000012758	zgc:77112 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:77112
chr24_-_31904924 Show fit	6.93	ENSDART00000156060 ENSDART00000129741 ENSDART00000154276	si:ch73-78o10.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-78o10.1
chr8_-_32385989 Show fit	6.74	ENSDART00000143716 ENSDART00000098850	lipg NCBI UniProt ZFIN ENSEMBL Google Show fit	lipase, endothelial
chr13_-_17943135 Show fit	6.52	ENSDART00000176027	march8 NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane-associated ring finger (C3HC4) 8
chr14_-_16807206 Show fit	6.44	ENSDART00000157957	tcirg1b NCBI UniProt ZFIN ENSEMBL Google Show fit	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr1_+_27977297 Show fit	6.43	ENSDART00000180692 ENSDART00000166819	sugt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr9_+_24088062 Show fit	6.34	ENSDART00000126198	lrrfip1a NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine rich repeat (in FLII) interacting protein 1a
chr8_+_52442785 Show fit	6.31	ENSDART00000189958	zgc:77112 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:77112
chr23_-_10177442 Show fit	6.27	ENSDART00000144280 ENSDART00000129044	krt5 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 5
chr21_-_4793686 Show fit	6.21	ENSDART00000158232	notch1a NCBI UniProt ZFIN ENSEMBL Google Show fit	notch 1a
chr6_+_40563848 Show fit	6.18	ENSDART00000154766	si:ch73-15b2.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-15b2.5
chr19_-_43750659 Show fit	6.14	ENSDART00000151309	ppt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr19_-_43750389 Show fit	6.13	ENSDART00000147328	ppt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr18_-_25771553 Show fit	6.05	ENSDART00000103046	zgc:162879 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162879
chr14_-_41467497 Show fit	6.00	ENSDART00000181220	mid1ip1l NCBI UniProt ZFIN ENSEMBL Google Show fit	MID1 interacting protein 1, like
chr19_+_10661520 Show fit	5.98	ENSDART00000091813 ENSDART00000165653	ago3b NCBI UniProt ZFIN ENSEMBL Google Show fit	argonaute RISC catalytic component 3b
chr6_-_39903393 Show fit	5.91	ENSDART00000085945	tsfm NCBI UniProt ZFIN ENSEMBL Google Show fit	Ts translation elongation factor, mitochondrial
chr15_+_6459847 Show fit	5.36	ENSDART00000157250 ENSDART00000065824	bace2 NCBI UniProt ZFIN ENSEMBL Google Show fit	beta-site APP-cleaving enzyme 2
chr16_-_42770064 Show fit	5.26	ENSDART00000112879	slc4a7 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_-_26601307 Show fit	5.23	ENSDART00000188934	plscr3b NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipid scramblase 3b
chr16_+_29509133 Show fit	5.20	ENSDART00000112116	ctss2.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin S, ortholog2, tandem duplicate 1
chr13_+_8840772 Show fit	5.20	ENSDART00000059321	epcam NCBI UniProt ZFIN ENSEMBL Google Show fit	epithelial cell adhesion molecule
chr15_+_20239141 Show fit	5.20	ENSDART00000101152 ENSDART00000152473	spint2 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine peptidase inhibitor, Kunitz type, 2
chr9_-_443451 Show fit	5.13	ENSDART00000165642	si:dkey-11f4.14 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-11f4.14
chr5_-_54712159 Show fit	5.07	ENSDART00000149207	ccnb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin B1
chr8_-_22558773 Show fit	4.96	ENSDART00000074309	porcnl NCBI UniProt ZFIN ENSEMBL Google Show fit	porcupine O-acyltransferase like
chr8_-_39884359 Show fit	4.93	ENSDART00000131372	mlec NCBI UniProt ZFIN ENSEMBL Google Show fit	malectin
chr6_-_8360918 Show fit	4.92	ENSDART00000004716	acp5a NCBI UniProt ZFIN ENSEMBL Google Show fit	acid phosphatase 5a, tartrate resistant
chr3_+_17939828 Show fit	4.89	ENSDART00000185047	cnp NCBI UniProt ZFIN ENSEMBL Google Show fit	2',3'-cyclic nucleotide 3' phosphodiesterase
chr5_-_69482891 Show fit	4.80	ENSDART00000109487	CABZ01032476.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr3_-_34547000 Show fit	4.70	ENSDART00000166623	sept9a NCBI UniProt ZFIN ENSEMBL Google Show fit	septin 9a
chr6_+_112579 Show fit	4.65	ENSDART00000034505	ap1m2 NCBI UniProt ZFIN ENSEMBL Google Show fit	adaptor-related protein complex 1, mu 2 subunit
chr5_-_47975440 Show fit	4.63	ENSDART00000145665 ENSDART00000007057	ccnh NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin H
chr3_-_15119856 Show fit	4.60	ENSDART00000138328	xpo6 NCBI UniProt ZFIN ENSEMBL Google Show fit	exportin 6
chr22_-_17652112 Show fit	4.54	ENSDART00000189205	hmha1b NCBI UniProt ZFIN ENSEMBL Google Show fit	histocompatibility (minor) HA-1 b
chr17_+_22577472 Show fit	4.54	ENSDART00000045099	yipf4 NCBI UniProt ZFIN ENSEMBL Google Show fit	Yip1 domain family, member 4
chr17_-_7733037 Show fit	4.53	ENSDART00000064657	stx11a NCBI UniProt ZFIN ENSEMBL Google Show fit	syntaxin 11a
chr6_-_42949184 Show fit	4.51	ENSDART00000147208	edem1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ER degradation enhancer, mannosidase alpha-like 1
chr2_-_44777592 Show fit	4.49	ENSDART00000113351 ENSDART00000169310	ncapd2 NCBI UniProt ZFIN ENSEMBL Google Show fit	non-SMC condensin I complex, subunit D2
chr4_-_5108844 Show fit	4.46	ENSDART00000132666 ENSDART00000136096	tmem209 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 209
chr20_+_23947004 Show fit	4.46	ENSDART00000144195	casp8ap2 NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase 8 associated protein 2
chr12_+_14149686 Show fit	4.45	ENSDART00000123741	kbtbd2 NCBI UniProt ZFIN ENSEMBL Google Show fit	kelch repeat and BTB (POZ) domain containing 2
chr6_+_46309795 Show fit	4.44	ENSDART00000154817	si:dkeyp-67f1.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-67f1.1
chr25_+_3759553 Show fit	4.42	ENSDART00000180601 ENSDART00000055845 ENSDART00000157050 ENSDART00000153905	thoc5 NCBI UniProt ZFIN ENSEMBL Google Show fit	THO complex 5
chr13_-_17860307 Show fit	4.38	ENSDART00000135920 ENSDART00000054579	march8 NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane-associated ring finger (C3HC4) 8
chr5_-_29195063 Show fit	4.37	ENSDART00000109926	man1b1b NCBI UniProt ZFIN ENSEMBL Google Show fit	mannosidase, alpha, class 1B, member 1b
chr3_-_34561624 Show fit	4.36	ENSDART00000129313	sept9a NCBI UniProt ZFIN ENSEMBL Google Show fit	septin 9a
chr10_+_15608326 Show fit	4.29	ENSDART00000188770	zfand5b NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, AN1-type domain 5b
chr7_-_39378903 Show fit	4.23	ENSDART00000173659	slc8b1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr3_+_18579806 Show fit	4.18	ENSDART00000180967 ENSDART00000089765	arhgap17b NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 17b
chr4_+_4079418 Show fit	4.17	ENSDART00000028016	waslb NCBI UniProt ZFIN ENSEMBL Google Show fit	Wiskott-Aldrich syndrome-like b
chr7_+_24153070 Show fit	4.17	ENSDART00000076735	lrp10 NCBI UniProt ZFIN ENSEMBL Google Show fit	low density lipoprotein receptor-related protein 10
chr10_+_14982977 Show fit	4.17	ENSDART00000140869	si:dkey-88l16.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-88l16.3
chr7_+_19483277 Show fit	4.16	ENSDART00000173750	si:ch211-212k18.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k18.7
chr4_-_77561679 Show fit	4.16	ENSDART00000180809	AL935186.9 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr13_-_24717365 Show fit	4.13	ENSDART00000137934 ENSDART00000003922	erlin1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ER lipid raft associated 1
chr19_+_7559901 Show fit	4.13	ENSDART00000141189	pbxip1a NCBI UniProt ZFIN ENSEMBL Google Show fit	pre-B-cell leukemia homeobox interacting protein 1a
chr12_-_35386910 Show fit	4.11	ENSDART00000153453	camk2g1 NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr21_+_28747069 Show fit	4.11	ENSDART00000014058	zgc:100829 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:100829
chr10_+_15025006 Show fit	4.09	ENSDART00000145192 ENSDART00000140084	si:dkey-88l16.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-88l16.5
chr12_-_18577983 Show fit	4.08	ENSDART00000193262	zdhhc4 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, DHHC-type containing 4
chr17_+_32623931 Show fit	4.06	ENSDART00000144217	ctsba NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin Ba
chr21_+_5192016 Show fit	4.05	ENSDART00000139288	si:dkey-121h17.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-121h17.7
chr20_-_28698172 Show fit	4.03	ENSDART00000190635	sipa1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	signal-induced proliferation-associated 1 like 1
chr1_+_59321629 Show fit	4.02	ENSDART00000161981	parn NCBI UniProt ZFIN ENSEMBL Google Show fit	poly(A)-specific ribonuclease (deadenylation nuclease)
chr23_-_22523303 Show fit	4.01	ENSDART00000079019	spsb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	splA/ryanodine receptor domain and SOCS box containing 1
chr7_+_39418869 Show fit	4.01	ENSDART00000169195	CT030188.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr8_-_7232413 Show fit	4.01	ENSDART00000092426	grip2a NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamate receptor interacting protein 2a
chr18_+_15271993 Show fit	4.01	ENSDART00000099777	si:dkey-103i16.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-103i16.6
chr2_+_24762567 Show fit	3.93	ENSDART00000078866	ifi30 NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon, gamma-inducible protein 30
chr5_-_29152457 Show fit	3.92	ENSDART00000078469	noxa1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NADPH oxidase activator 1
chr17_-_43031763 Show fit	3.92	ENSDART00000132754 ENSDART00000050399	npc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	Niemann-Pick disease, type C2
chr14_+_35428152 Show fit	3.91	ENSDART00000172597	sytl4 NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptotagmin-like 4
chr13_-_35760969 Show fit	3.88	ENSDART00000127476	erlec1 NCBI UniProt ZFIN ENSEMBL Google Show fit	endoplasmic reticulum lectin 1
chr19_+_42086862 Show fit	3.85	ENSDART00000151605	nfyc NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear transcription factor Y, gamma
chr23_+_40133136 Show fit	3.84	ENSDART00000157616	gpsm2l NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein signaling modulator 2, like
chr18_+_27598755 Show fit	3.81	ENSDART00000193808	cd82b NCBI UniProt ZFIN ENSEMBL Google Show fit	CD82 molecule b
chr1_+_12301913 Show fit	3.80	ENSDART00000165733	gne NCBI UniProt ZFIN ENSEMBL Google Show fit	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr14_+_30285613 Show fit	3.79	ENSDART00000173090	mtus1a NCBI UniProt ZFIN ENSEMBL Google Show fit	microtubule associated tumor suppressor 1a
chr8_+_7875110 Show fit	3.79	ENSDART00000167423 ENSDART00000160267 ENSDART00000180490	mbd1a NCBI UniProt ZFIN ENSEMBL Google Show fit	methyl-CpG binding domain protein 1a
chr12_-_18577774 Show fit	3.77	ENSDART00000078166	zdhhc4 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, DHHC-type containing 4
chr15_+_38299385 Show fit	3.77	ENSDART00000142403	si:dkey-24p1.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-24p1.6
chr3_+_19665319 Show fit	3.77	ENSDART00000007857 ENSDART00000193509	mettl2a NCBI UniProt ZFIN ENSEMBL Google Show fit	methyltransferase like 2A
chr23_-_31648026 Show fit	3.77	ENSDART00000133569	sgk1 NCBI UniProt ZFIN ENSEMBL Google Show fit	serum/glucocorticoid regulated kinase 1
chr6_-_33916756 Show fit	3.77	ENSDART00000137447 ENSDART00000138488	nasp NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear autoantigenic sperm protein (histone-binding)
chr20_-_14718801 Show fit	3.76	ENSDART00000137605	suco NCBI UniProt ZFIN ENSEMBL Google Show fit	SUN domain containing ossification factor
chr6_-_17849786 Show fit	3.76	ENSDART00000172709	rptor NCBI UniProt ZFIN ENSEMBL Google Show fit	regulatory associated protein of MTOR, complex 1
chr15_+_21711671 Show fit	3.76	ENSDART00000136151	NKAPD1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162339
chr3_-_34136778 Show fit	3.72	ENSDART00000131951	clpp NCBI UniProt ZFIN ENSEMBL Google Show fit	caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr3_+_27664864 Show fit	3.72	ENSDART00000126533 ENSDART00000180848	clcn7 NCBI UniProt ZFIN ENSEMBL Google Show fit	chloride channel 7
chr22_+_26600834 Show fit	3.69	ENSDART00000157411	adcy9 NCBI UniProt ZFIN ENSEMBL Google Show fit	adenylate cyclase 9
chr3_-_40232615 Show fit	3.69	ENSDART00000155969	flii NCBI UniProt ZFIN ENSEMBL Google Show fit	flightless I actin binding protein
chr8_+_20415824 Show fit	3.68	ENSDART00000009081 ENSDART00000145444	mob3a NCBI UniProt ZFIN ENSEMBL Google Show fit	MOB kinase activator 3A
chr17_-_29271359 Show fit	3.68	ENSDART00000104219	rcor1 NCBI UniProt ZFIN ENSEMBL Google Show fit	REST corepressor 1
chr14_-_46198373 Show fit	3.68	ENSDART00000031640 ENSDART00000132966	zgc:113425 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113425
chr2_+_31942390 Show fit	3.67	ENSDART00000138684 ENSDART00000146758 ENSDART00000137921	otulinb NCBI UniProt ZFIN ENSEMBL Google Show fit	OTU deubiquitinase with linear linkage specificity b
chr5_-_29512538 Show fit	3.67	ENSDART00000098364	ehmt1a NCBI UniProt ZFIN ENSEMBL Google Show fit	euchromatic histone-lysine N-methyltransferase 1a
chr2_-_19234329 Show fit	3.67	ENSDART00000161106 ENSDART00000160060 ENSDART00000174552	cdc20 NCBI UniProt ZFIN ENSEMBL Google Show fit	cell division cycle 20 homolog
chr8_-_16650595 Show fit	3.66	ENSDART00000135319	osbpl9 NCBI UniProt ZFIN ENSEMBL Google Show fit	oxysterol binding protein-like 9
chr12_-_10508952 Show fit	3.66	ENSDART00000152806	zgc:152977 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:152977
chr4_+_26056548 Show fit	3.65	ENSDART00000171204	SCYL2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-244b2.1
chr7_+_34794829 Show fit	3.65	ENSDART00000009698 ENSDART00000075089 ENSDART00000173456	esrp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	epithelial splicing regulatory protein 2
chr4_-_4250317 Show fit	3.64	ENSDART00000103316	cd9b NCBI UniProt ZFIN ENSEMBL Google Show fit	CD9 molecule b
chr5_-_29514689 Show fit	3.64	ENSDART00000126018 ENSDART00000125175	ehmt1a NCBI UniProt ZFIN ENSEMBL Google Show fit	euchromatic histone-lysine N-methyltransferase 1a
chr19_-_8812891 Show fit	3.62	ENSDART00000151134 ENSDART00000025385 ENSDART00000180291	cers2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ceramide synthase 2a
chr7_+_24023653 Show fit	3.61	ENSDART00000141165	tinf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	TERF1 (TRF1)-interacting nuclear factor 2
chr4_-_5795309 Show fit	3.61	ENSDART00000039987	pgm3 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoglucomutase 3
chr3_-_26191960 Show fit	3.61	ENSDART00000113843	ypel3 NCBI UniProt ZFIN ENSEMBL Google Show fit	yippee-like 3
chr6_-_49547680 Show fit	3.59	ENSDART00000169678	ppp4r1l NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 4, regulatory subunit 1-like
chr19_+_43523690 Show fit	3.59	ENSDART00000113031	wasf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	WAS protein family, member 2
chr13_+_28785814 Show fit	3.59	ENSDART00000039028	nsmce4a NCBI UniProt ZFIN ENSEMBL Google Show fit	NSE4 homolog A, SMC5-SMC6 complex component
chr21_-_43665537 Show fit	3.58	ENSDART00000157610	si:dkey-229d11.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-229d11.3
chr6_+_40554551 Show fit	3.57	ENSDART00000017859 ENSDART00000155928	ddi2 NCBI UniProt ZFIN ENSEMBL Google Show fit	DNA-damage inducible protein 2
chr5_+_20453874 Show fit	3.56	ENSDART00000124545 ENSDART00000008402	sart3 NCBI UniProt ZFIN ENSEMBL Google Show fit	squamous cell carcinoma antigen recognized by T cells 3
chr3_-_40051425 Show fit	3.55	ENSDART00000146700	llgl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	lethal giant larvae homolog 1 (Drosophila)
chr10_+_44956660 Show fit	3.53	ENSDART00000169225 ENSDART00000189298	il1b NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 1, beta
chr13_+_22719789 Show fit	3.53	ENSDART00000057672	nfkb2 NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_50954607 Show fit	3.52	ENSDART00000163810	cdc42ep4a NCBI UniProt ZFIN ENSEMBL Google Show fit	CDC42 effector protein (Rho GTPase binding) 4a
chr9_-_11655031 Show fit	3.52	ENSDART00000044314	itgav NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, alpha V
chr1_-_49521407 Show fit	3.51	ENSDART00000189845 ENSDART00000143474	zp3c NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3c
chr5_+_39099172 Show fit	3.50	ENSDART00000006079	bmp2k NCBI UniProt ZFIN ENSEMBL Google Show fit	BMP2 inducible kinase
chr7_-_24112484 Show fit	3.49	ENSDART00000111923	ajuba NCBI UniProt ZFIN ENSEMBL Google Show fit	ajuba LIM protein
chr6_+_29860776 Show fit	3.48	ENSDART00000028406	dlg1 NCBI UniProt ZFIN ENSEMBL Google Show fit	discs, large homolog 1 (Drosophila)
chr8_-_30742233 Show fit	3.47	ENSDART00000098986	gucd1 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanylyl cyclase domain containing 1
chr4_-_10835620 Show fit	3.46	ENSDART00000150739	ppfibp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr19_+_30867845 Show fit	3.46	ENSDART00000047461	mfsd2ab NCBI UniProt ZFIN ENSEMBL Google Show fit	major facilitator superfamily domain containing 2ab
chr24_+_14801844 Show fit	3.45	ENSDART00000141620	pi15a NCBI UniProt ZFIN ENSEMBL Google Show fit	peptidase inhibitor 15a
chr19_-_34063567 Show fit	3.45	ENSDART00000157815 ENSDART00000183907	elmo1 NCBI UniProt ZFIN ENSEMBL Google Show fit	engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr5_-_69948099 Show fit	3.45	ENSDART00000034639 ENSDART00000191111	ugt2a4 NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP glucuronosyltransferase 2 family, polypeptide A4
chr10_+_2842923 Show fit	3.44	ENSDART00000181895	ykt6 NCBI UniProt ZFIN ENSEMBL Google Show fit	YKT6 v-SNARE homolog (S. cerevisiae)
chr24_+_25210015 Show fit	3.43	ENSDART00000081043	cip2a NCBI UniProt ZFIN ENSEMBL Google Show fit	cell proliferation regulating inhibitor of protein phosphatase 2A
chr14_+_24845941 Show fit	3.42	ENSDART00000187513	arhgef37 NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho guanine nucleotide exchange factor (GEF) 37
chr25_-_12410198 Show fit	3.42	ENSDART00000182281	det1 NCBI UniProt ZFIN ENSEMBL Google Show fit	DET1, COP1 ubiquitin ligase partner
chr5_+_40835601 Show fit	3.42	ENSDART00000147767	si:dkey-3h3.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-3h3.3
chr22_-_5822147 Show fit	3.41	ENSDART00000011076	cers5 NCBI UniProt ZFIN ENSEMBL Google Show fit	ceramide synthase 5
chr23_+_28378543 Show fit	3.40	ENSDART00000145327	zgc:153867 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:153867
chr7_+_36472789 Show fit	3.40	ENSDART00000136545	aktip NCBI UniProt ZFIN ENSEMBL Google Show fit	akt interacting protein
chr10_+_26944978 Show fit	3.39	ENSDART00000192148	frmd8 NCBI UniProt ZFIN ENSEMBL Google Show fit	FERM domain containing 8
chr10_+_14963898 Show fit	3.36	ENSDART00000187363 ENSDART00000175732	si:dkey-88l16.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-88l16.3
chr1_+_12394205 Show fit	3.35	ENSDART00000138622 ENSDART00000136421 ENSDART00000139440 ENSDART00000184296 ENSDART00000008127	zgc:77739 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:77739
chr22_-_3299100 Show fit	3.34	ENSDART00000160305	si:zfos-943e10.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-943e10.1
chr3_-_1263047 Show fit	3.34	ENSDART00000184388	tcf20 NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription factor 20
chr10_+_5234327 Show fit	3.34	ENSDART00000133927 ENSDART00000063120	sptlc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine palmitoyltransferase, long chain base subunit 1
chr2_+_30249977 Show fit	3.33	ENSDART00000109160 ENSDART00000135171	tmem70 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 70
chr2_-_21167652 Show fit	3.33	ENSDART00000185792	bmi1b NCBI UniProt ZFIN ENSEMBL Google Show fit	bmi1 polycomb ring finger oncogene 1b
chr19_-_31765615 Show fit	3.33	ENSDART00000103636	si:dkeyp-120h9.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-120h9.1
chr23_+_40139765 Show fit	3.32	ENSDART00000185376	gpsm2l NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein signaling modulator 2, like
chr13_-_25408387 Show fit	3.32	ENSDART00000002741	itprip NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol 1,4,5-trisphosphate receptor interacting protein
chr21_+_25120546 Show fit	3.31	ENSDART00000149507	ddx10 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr15_+_24737599 Show fit	3.28	ENSDART00000078024	crk NCBI UniProt ZFIN ENSEMBL Google Show fit	v-crk avian sarcoma virus CT10 oncogene homolog
chr8_+_15269423 Show fit	3.27	ENSDART00000020386	gclm NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamate-cysteine ligase, modifier subunit
chr9_+_2762270 Show fit	3.26	ENSDART00000123342 ENSDART00000001795 ENSDART00000177563	sp3a NCBI UniProt ZFIN ENSEMBL Google Show fit	sp3a transcription factor
chr15_+_20281305 Show fit	3.26	ENSDART00000155065	plekhg2 NCBI UniProt ZFIN ENSEMBL Google Show fit	pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr13_-_8785610 Show fit	3.26	ENSDART00000021083	calm2b NCBI UniProt ZFIN ENSEMBL Google Show fit	calmodulin 2b, (phosphorylase kinase, delta)
chr3_-_40254634 Show fit	3.26	ENSDART00000154562	top3a NCBI UniProt ZFIN ENSEMBL Google Show fit	DNA topoisomerase III alpha
chr20_+_9223514 Show fit	3.25	ENSDART00000023293	kcnk5b NCBI UniProt ZFIN ENSEMBL Google Show fit	potassium channel, subfamily K, member 5b
chr3_+_27665160 Show fit	3.24	ENSDART00000103660	clcn7 NCBI UniProt ZFIN ENSEMBL Google Show fit	chloride channel 7
chr14_+_32918484 Show fit	3.23	ENSDART00000105721	lnx2b NCBI UniProt ZFIN ENSEMBL Google Show fit	ligand of numb-protein X 2b
chr18_-_11595567 Show fit	3.23	ENSDART00000098565	CRACR2A NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium release activated channel regulator 2A
chr7_-_60351876 Show fit	3.23	ENSDART00000098563	plcb3 NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipase C, beta 3 (phosphatidylinositol-specific)
chr8_+_3431671 Show fit	3.22	ENSDART00000017850	ctu1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr18_+_3634652 Show fit	3.21	ENSDART00000159913	lrch3 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine-rich repeats and calponin homology (CH) domain containing 3
chr20_-_34028967 Show fit	3.19	ENSDART00000153408 ENSDART00000033817	scyl3 NCBI UniProt ZFIN ENSEMBL Google Show fit	SCY1-like, kinase-like 3
chr1_-_31105376 Show fit	3.19	ENSDART00000132466	ppp1r9alb NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 1 regulatory subunit 9A-like B
chr10_-_28380919 Show fit	3.18	ENSDART00000183409 ENSDART00000183105 ENSDART00000100207 ENSDART00000185392 ENSDART00000131220	btg3 NCBI UniProt ZFIN ENSEMBL Google Show fit	B-cell translocation gene 3
chr20_-_54198130 Show fit	3.18	ENSDART00000160409	arf6a NCBI UniProt ZFIN ENSEMBL Google Show fit	ADP-ribosylation factor 6a
chr18_+_45666489 Show fit	3.17	ENSDART00000180147 ENSDART00000151351	prrg4 NCBI UniProt ZFIN ENSEMBL Google Show fit	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr10_-_24765988 Show fit	3.17	ENSDART00000064463	timm10b NCBI UniProt ZFIN ENSEMBL Google Show fit	translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr20_-_35470891 Show fit	3.17	ENSDART00000152993 ENSDART00000016090	pla2g7 NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr15_+_11693624 Show fit	3.16	ENSDART00000193630 ENSDART00000161930	strn4 NCBI UniProt ZFIN ENSEMBL Google Show fit	striatin, calmodulin binding protein 4
chr17_+_21126495 Show fit	3.15	ENSDART00000022830	pygb NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphorylase, glycogen; brain
chr18_-_20444296 Show fit	3.13	ENSDART00000132993	kif23 NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 23
chr21_-_13856689 Show fit	3.12	ENSDART00000102197	fam129ba NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 129, member Ba
chr21_+_25765734 Show fit	3.12	ENSDART00000021664	cldnb NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin b
chr21_-_44771213 Show fit	3.12	ENSDART00000188534	kif4 NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 4
chr6_-_3998199 Show fit	3.11	ENSDART00000059212	unc50 NCBI UniProt ZFIN ENSEMBL Google Show fit	unc-50 homolog (C. elegans)
chr25_+_2361721 Show fit	3.11	ENSDART00000172905	zmp:0000000932 NCBI UniProt ZFIN ENSEMBL Google Show fit	zmp:0000000932
chr7_-_60351537 Show fit	3.11	ENSDART00000159875	plcb3 NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipase C, beta 3 (phosphatidylinositol-specific)
chr15_+_12429206 Show fit	3.09	ENSDART00000168997	tmprss4a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protease, serine 4a
chr21_-_25295087 Show fit	3.08	ENSDART00000087910 ENSDART00000147860	st14b NCBI UniProt ZFIN ENSEMBL Google Show fit	suppression of tumorigenicity 14 (colon carcinoma) b
chr21_+_28747236 Show fit	3.08	ENSDART00000137874	zgc:100829 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:100829
chr5_+_28260158 Show fit	3.07	ENSDART00000181434	ncaph NCBI UniProt ZFIN ENSEMBL Google Show fit	non-SMC condensin I complex, subunit H
chr17_-_30652738 Show fit	3.07	ENSDART00000154960	sh3yl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3 and SYLF domain containing 1
chr7_+_34487833 Show fit	3.07	ENSDART00000173854	cln6a NCBI UniProt ZFIN ENSEMBL Google Show fit	CLN6, transmembrane ER protein a
chr15_-_28904371 Show fit	3.05	ENSDART00000155154	eml2 NCBI UniProt ZFIN ENSEMBL Google Show fit	echinoderm microtubule associated protein like 2
chr12_-_8958353 Show fit	3.04	ENSDART00000041728	cyp26a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 26, subfamily A, polypeptide 1
chr14_+_32918172 Show fit	3.02	ENSDART00000182867	lnx2b NCBI UniProt ZFIN ENSEMBL Google Show fit	ligand of numb-protein X 2b
chr7_-_59165640 Show fit	3.02	ENSDART00000170853	haus6 NCBI UniProt ZFIN ENSEMBL Google Show fit	HAUS augmin-like complex, subunit 6
chr25_+_19238175 Show fit	3.02	ENSDART00000110730 ENSDART00000193619 ENSDART00000154420	ppip5k1b NCBI UniProt ZFIN ENSEMBL Google Show fit	diphosphoinositol pentakisphosphate kinase 1b
chr12_+_27231607 Show fit	3.02	ENSDART00000066270	tmem106a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 106A
chr8_-_22531817 Show fit	3.01	ENSDART00000140606	csde1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cold shock domain containing E1, RNA-binding
chr20_+_2642855 Show fit	3.01	ENSDART00000058775	zgc:101562 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:101562
chr9_+_33154841 Show fit	3.00	ENSDART00000132465	dopey2 NCBI UniProt ZFIN ENSEMBL Google Show fit	dopey family member 2
chr9_-_12269847 Show fit	2.99	ENSDART00000136558 ENSDART00000144734 ENSDART00000131766 ENSDART00000032344	nup35 NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleoporin 35

Network of associatons between targets according to the STRING database.

First level regulatory network of spi1a+spi1b

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	10.9	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
2.2	6.5	GO:0070125	mitochondrial translational elongation(GO:0070125)
2.1	6.2	GO:0021531	spinal cord radial glial cell differentiation(GO:0021531)
1.7	5.0	GO:0061355	Wnt protein secretion(GO:0061355)
1.3	5.3	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.2	16.2	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
1.2	4.8	GO:0071871	response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
1.2	3.6	GO:0090085	regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
1.2	5.9	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
1.2	3.5	GO:0060148	negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.1	4.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
1.1	3.3	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.1	3.3	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
1.1	4.4	GO:0071788	endoplasmic reticulum tubular network maintenance(GO:0071788)
1.0	3.0	GO:0060031	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031)
0.9	3.8	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.9	7.1	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.9	4.4	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.9	3.5	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.9	2.6	GO:0003218	cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218) pericardium development(GO:0060039)
0.8	3.4	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.8	2.5	GO:0021512	spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.8	3.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.8	2.4	GO:0035046	pronuclear migration(GO:0035046)
0.8	2.4	GO:1901004	ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.8	3.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.8	2.3	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8	2.3	GO:0071236	cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.7	2.2	GO:0097095	frontonasal suture morphogenesis(GO:0097095)
0.7	2.2	GO:0010657	negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.7	16.3	GO:0032885	regulation of polysaccharide biosynthetic process(GO:0032885)
0.7	6.4	GO:0006465	signal peptide processing(GO:0006465)
0.7	3.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.7	2.7	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.7	1.4	GO:0007220	Notch receptor processing(GO:0007220)
0.7	5.3	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.7	2.0	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.7	3.9	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.6	3.2	GO:0045056	transcytosis(GO:0045056)
0.6	3.7	GO:1990108	protein linear deubiquitination(GO:1990108)
0.6	3.7	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.6	6.0	GO:0072091	regulation of stem cell proliferation(GO:0072091)
0.6	2.4	GO:0034729	histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.6	3.5	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.6	1.7	GO:0019852	L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.6	3.9	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6	5.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.6	2.8	GO:0030327	prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.6	1.7	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.5	2.7	GO:0042264	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.5	2.7	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.5	6.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.5	9.2	GO:0035803	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.5	1.1	GO:0045730	respiratory burst(GO:0045730)
0.5	5.4	GO:0031274	pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.5	3.2	GO:0032447	tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.5	2.1	GO:2000815	regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.5	4.3	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.5	2.6	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.5	3.7	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.5	14.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.5	5.7	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.5	3.1	GO:0048714	positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.5	6.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.5	2.0	GO:0099563	modification of synaptic structure(GO:0099563)
0.5	4.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.5	2.5	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.5	1.5	GO:0005997	xylulose metabolic process(GO:0005997)
0.5	2.5	GO:0033499	galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.5	3.9	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5	1.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.5	2.8	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.5	1.4	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.5	2.3	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.5	1.9	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332) cell-cell junction maintenance(GO:0045217)
0.5	1.8	GO:0010668	ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.5	5.5	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.5	3.2	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5	6.4	GO:0051452	vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.5	6.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.5	3.2	GO:0036010	protein localization to endosome(GO:0036010)
0.4	3.1	GO:0040016	embryonic cleavage(GO:0040016)
0.4	4.9	GO:0006611	protein export from nucleus(GO:0006611)
0.4	1.3	GO:0045453	bone resorption(GO:0045453)
0.4	2.7	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.4	2.2	GO:0015744	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4	3.9	GO:0016246	RNA interference(GO:0016246)
0.4	1.3	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.4	6.5	GO:0051127	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4	4.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.4	1.3	GO:0000390	spliceosomal complex disassembly(GO:0000390)
0.4	8.4	GO:0030149	sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.4	2.1	GO:0010586	miRNA metabolic process(GO:0010586)
0.4	5.8	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.4	12.7	GO:0017121	phospholipid scrambling(GO:0017121)
0.4	2.0	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.4	2.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4	0.8	GO:0035973	aggrephagy(GO:0035973)
0.4	3.5	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.4	6.6	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.4	4.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.4	2.3	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.4	3.8	GO:0046850	regulation of bone remodeling(GO:0046850)
0.4	2.6	GO:1990253	response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.4	6.6	GO:0043114	regulation of vascular permeability(GO:0043114)
0.4	1.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.4	1.1	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.4	1.1	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4	7.0	GO:0007032	endosome organization(GO:0007032)
0.4	6.7	GO:0008354	germ cell migration(GO:0008354)
0.4	1.1	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3	1.4	GO:0070131	regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.3	1.4	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.3	1.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.3	5.8	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.3	1.0	GO:0046443	FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.3	4.1	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.3	2.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3	1.7	GO:0010828	positive regulation of glucose transport(GO:0010828)
0.3	2.0	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.3	1.3	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3	4.3	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3	5.6	GO:0019433	triglyceride catabolic process(GO:0019433)
0.3	2.0	GO:0019427	acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.3	1.0	GO:1902767	farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.3	4.5	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.3	1.9	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3	2.8	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3	2.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.3	3.7	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.3	2.4	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3	1.8	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.3	0.9	GO:0032197	regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.3	0.9	GO:0048194	Golgi vesicle budding(GO:0048194)
0.3	3.6	GO:1904356	regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.3	0.9	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3	1.5	GO:0090024	negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.3	6.7	GO:0006491	N-glycan processing(GO:0006491)
0.3	1.4	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.3	1.1	GO:0036306	embryonic heart tube elongation(GO:0036306)
0.3	2.3	GO:0044528	regulation of mitochondrial mRNA stability(GO:0044528)
0.3	6.5	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3	1.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3	8.9	GO:0048920	posterior lateral line neuromast primordium migration(GO:0048920)
0.3	1.9	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3	1.9	GO:0008063	Toll signaling pathway(GO:0008063)
0.3	3.0	GO:0006999	nuclear pore organization(GO:0006999)
0.3	8.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.3	1.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.3	1.1	GO:0018008	N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) protein myristoylation(GO:0018377)
0.3	2.4	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.3	2.3	GO:0006857	oligopeptide transport(GO:0006857)
0.3	2.8	GO:0038203	TORC2 signaling(GO:0038203)
0.3	13.3	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.3	1.8	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.3	0.8	GO:0050427	sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2	2.2	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2	2.5	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2	5.4	GO:2000134	negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2	1.7	GO:0032475	otolith formation(GO:0032475)
0.2	0.7	GO:2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.2	3.2	GO:0006020	inositol metabolic process(GO:0006020)
0.2	2.2	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	2.1	GO:0030104	water homeostasis(GO:0030104)
0.2	1.9	GO:0042554	superoxide anion generation(GO:0042554)
0.2	3.2	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.2	2.0	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.2	1.1	GO:1904036	negative regulation of epithelial cell apoptotic process(GO:1904036)
0.2	8.7	GO:0031647	regulation of protein stability(GO:0031647)
0.2	0.4	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.2	7.5	GO:0051209	release of sequestered calcium ion into cytosol(GO:0051209)
0.2	0.9	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2	1.1	GO:0003173	ventriculo bulbo valve development(GO:0003173)
0.2	0.9	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.2	1.1	GO:0070650	actin filament bundle distribution(GO:0070650)
0.2	1.9	GO:0046247	carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2	1.3	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2	1.7	GO:0019430	response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2	1.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.2	1.5	GO:0048823	nucleate erythrocyte development(GO:0048823)
0.2	1.7	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	3.5	GO:0038202	TORC1 signaling(GO:0038202)
0.2	0.8	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.2	0.4	GO:0042256	mature ribosome assembly(GO:0042256)
0.2	2.6	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2	1.4	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.2	1.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	2.9	GO:2000223	regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.2	1.0	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.2	1.6	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2	6.4	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	4.2	GO:0015701	bicarbonate transport(GO:0015701)
0.2	1.5	GO:0034063	stress granule assembly(GO:0034063)
0.2	1.3	GO:0050820	positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2	1.7	GO:0007584	response to nutrient(GO:0007584)
0.2	2.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.2	1.1	GO:0031284	regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.2	0.4	GO:0060823	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.2	2.0	GO:0035587	adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2	2.8	GO:0061055	myotome development(GO:0061055)
0.2	2.0	GO:0051597	response to methylmercury(GO:0051597)
0.2	1.7	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2	1.8	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2	0.9	GO:0071939	vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.2	4.8	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.2	3.9	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.2	2.3	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2	5.3	GO:0051014	actin filament severing(GO:0051014)
0.2	1.6	GO:0035479	angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.2	1.7	GO:0043931	ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.2	2.7	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	6.2	GO:0097205	renal filtration(GO:0097205)
0.2	1.7	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.2	0.7	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2	1.2	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.2	0.5	GO:0009193	pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2	0.7	GO:1903292	protein localization to Golgi membrane(GO:1903292)
0.2	1.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.2	5.6	GO:0030488	tRNA methylation(GO:0030488)
0.2	1.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2	2.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2	1.7	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.2	1.3	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.2	5.8	GO:0071897	DNA biosynthetic process(GO:0071897)
0.2	6.8	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.2	1.4	GO:0003428	growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2	6.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2	1.5	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154)
0.2	1.8	GO:0033198	response to ATP(GO:0033198)
0.1	7.9	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.1	3.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.4	GO:0009397	10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1	0.4	GO:0060967	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1	0.4	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.1	4.1	GO:0007338	single fertilization(GO:0007338)
0.1	1.5	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1	5.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1	4.9	GO:0031103	axon regeneration(GO:0031103)
0.1	2.9	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	0.6	GO:0050926	regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1	0.8	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.8	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.1	2.4	GO:0015693	magnesium ion transport(GO:0015693)
0.1	1.5	GO:0044247	polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	0.7	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	2.4	GO:0043486	histone exchange(GO:0043486)
0.1	10.3	GO:0045930	negative regulation of mitotic cell cycle(GO:0045930)
0.1	4.5	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	5.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	1.5	GO:0060325	head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.1	6.8	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.1	11.0	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.1	0.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	2.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	2.9	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	1.3	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.1	2.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.1	0.9	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	0.4	GO:1904871	positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1	0.6	GO:2000001	regulation of cell cycle checkpoint(GO:1901976) regulation of DNA damage checkpoint(GO:2000001)
0.1	1.3	GO:0046037	GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1	0.7	GO:0016048	detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1	0.4	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	1.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.1	2.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	7.8	GO:0016571	histone methylation(GO:0016571)
0.1	2.5	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	2.8	GO:0006884	cell volume homeostasis(GO:0006884)
0.1	2.3	GO:0071456	cellular response to hypoxia(GO:0071456)
0.1	3.0	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	22.2	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.1	0.8	GO:0090497	mesenchymal cell migration(GO:0090497)
0.1	0.7	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.8	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.1	6.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	1.6	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	1.0	GO:0061098	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of protein tyrosine kinase activity(GO:0061098) positive regulation of receptor activity(GO:2000273)
0.1	0.8	GO:0035264	multicellular organism growth(GO:0035264)
0.1	5.8	GO:0045766	positive regulation of angiogenesis(GO:0045766)
0.1	0.3	GO:0071586	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1	4.6	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.1	2.6	GO:0001878	response to yeast(GO:0001878)
0.1	2.9	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
0.1	8.8	GO:0007051	spindle organization(GO:0007051)
0.1	2.8	GO:0006828	manganese ion transport(GO:0006828)
0.1	1.2	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	2.2	GO:0034112	positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1	2.5	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.1	1.4	GO:0048263	determination of dorsal identity(GO:0048263)
0.1	0.4	GO:0006953	acute-phase response(GO:0006953)
0.1	1.0	GO:0070309	lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1	2.2	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	0.8	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.1	0.4	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1	2.3	GO:0072114	pronephros morphogenesis(GO:0072114)
0.1	1.5	GO:0016926	protein desumoylation(GO:0016926)
0.1	2.7	GO:0006998	nuclear envelope organization(GO:0006998)
0.1	1.4	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	0.1	GO:0002228	natural killer cell mediated immunity(GO:0002228) positive regulation of lymphocyte mediated immunity(GO:0002708) regulation of natural killer cell mediated immunity(GO:0002715) positive regulation of natural killer cell mediated immunity(GO:0002717) natural killer cell mediated cytotoxicity(GO:0042267) regulation of natural killer cell mediated cytotoxicity(GO:0042269) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	1.8	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.4	GO:0031048	chromatin silencing by small RNA(GO:0031048)
0.1	2.9	GO:0032924	activin receptor signaling pathway(GO:0032924)
0.1	1.8	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	1.5	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1	0.4	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	1.3	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.9	GO:0019883	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	2.0	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.7	GO:1900026	regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	1.4	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	1.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	2.1	GO:0072348	sulfur compound transport(GO:0072348)
0.1	1.3	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.7	GO:2001240	histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1	0.6	GO:0018196	peptidyl-asparagine modification(GO:0018196)
0.1	0.5	GO:0006301	postreplication repair(GO:0006301)
0.1	1.2	GO:1903288	positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	1.1	GO:0034453	microtubule anchoring(GO:0034453)
0.1	6.8	GO:0006821	chloride transport(GO:0006821)
0.1	0.2	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.1	0.5	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.1	1.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	3.7	GO:0044744	protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1	2.1	GO:0009395	phospholipid catabolic process(GO:0009395)
0.1	1.3	GO:0061462	protein localization to lysosome(GO:0061462)
0.1	0.7	GO:0043951	regulation of cAMP-mediated signaling(GO:0043949) negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	5.5	GO:0031101	fin regeneration(GO:0031101)
0.1	1.1	GO:0016441	posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.1	3.0	GO:0070830	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1	1.8	GO:0070593	dendrite self-avoidance(GO:0070593)
0.1	1.8	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	0.5	GO:0034033	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1	2.0	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	3.2	GO:0048015	phosphatidylinositol-mediated signaling(GO:0048015)
0.1	0.3	GO:0050938	regulation of xanthophore differentiation(GO:0050938)
0.1	2.0	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	0.5	GO:1902742	apoptotic process involved in development(GO:1902742)
0.1	0.2	GO:0015074	DNA integration(GO:0015074)
0.1	2.4	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1	1.6	GO:0007492	endoderm development(GO:0007492)
0.1	0.7	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	1.2	GO:0006446	regulation of translational initiation(GO:0006446)
0.1	1.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	3.2	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	0.3	GO:0045176	asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.1	3.6	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.5	GO:0071684	hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1	0.4	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1	0.5	GO:0046320	regulation of fatty acid beta-oxidation(GO:0031998) regulation of fatty acid oxidation(GO:0046320)
0.1	0.5	GO:0046632	alpha-beta T cell differentiation(GO:0046632)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.6	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	1.1	GO:0022011	myelination in peripheral nervous system(GO:0022011)
0.0	7.5	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	2.4	GO:0045765	regulation of angiogenesis(GO:0045765)
0.0	3.3	GO:0008033	tRNA processing(GO:0008033)
0.0	0.2	GO:1903723	negative regulation of centriole elongation(GO:1903723)
0.0	1.5	GO:0030336	negative regulation of cell migration(GO:0030336)
0.0	0.6	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	3.4	GO:0032147	activation of protein kinase activity(GO:0032147)
0.0	0.9	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	1.6	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.5	GO:1903311	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	3.1	GO:0043065	positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0	2.1	GO:0055088	lipid homeostasis(GO:0055088)
0.0	2.6	GO:0045055	regulated exocytosis(GO:0045055)
0.0	0.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	3.6	GO:0051604	protein maturation(GO:0051604)
0.0	1.1	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	1.5	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	1.6	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	2.6	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	1.0	GO:0032465	regulation of cytokinesis(GO:0032465)
0.0	0.2	GO:0045444	fat cell differentiation(GO:0045444)
0.0	0.4	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.6	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0055014	atrial cardiac muscle cell development(GO:0055014)
0.0	0.3	GO:0044042	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0	0.6	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.9	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	1.8	GO:0009190	cyclic nucleotide biosynthetic process(GO:0009190)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.2	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.4	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	1.3	GO:0006401	RNA catabolic process(GO:0006401)
0.0	0.2	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.1	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.0	0.3	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.8	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.3	GO:0050728	negative regulation of inflammatory response(GO:0050728)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) dopamine metabolic process(GO:0042417) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0015800	acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0	0.6	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	1.0	GO:0048846	axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0	0.1	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	1.1	GO:0006887	exocytosis(GO:0006887)
0.0	0.4	GO:0034204	lipid translocation(GO:0034204)
0.0	0.6	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
1.2	4.8	GO:0097524	sperm plasma membrane(GO:0097524)
1.1	3.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.1	4.2	GO:1990498	mitotic spindle microtubule(GO:1990498)
1.1	4.2	GO:0044609	DBIRD complex(GO:0044609)
1.0	4.1	GO:0005787	signal peptidase complex(GO:0005787)
1.0	8.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.9	6.9	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8	2.5	GO:0097189	apoptotic body(GO:0097189)
0.8	2.4	GO:0098826	endoplasmic reticulum tubular network membrane(GO:0098826)
0.8	2.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.8	12.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.7	6.0	GO:0000796	condensin complex(GO:0000796)
0.7	5.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.7	5.2	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.7	2.7	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.7	7.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.6	6.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.6	6.8	GO:0005675	holo TFIIH complex(GO:0005675)
0.6	3.7	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.6	4.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.6	3.0	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.6	1.8	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.6	2.9	GO:0034657	GID complex(GO:0034657)
0.6	2.3	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.6	2.3	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.6	3.4	GO:0070695	FHF complex(GO:0070695)
0.6	1.7	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5	8.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.5	5.2	GO:0045095	keratin filament(GO:0045095)
0.5	3.8	GO:0031931	TORC1 complex(GO:0031931)
0.4	1.8	GO:0098890	extrinsic component of postsynaptic membrane(GO:0098890)
0.4	10.1	GO:0030667	secretory granule membrane(GO:0030667)
0.4	2.6	GO:0005913	cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.4	3.7	GO:0071797	LUBAC complex(GO:0071797)
0.4	2.0	GO:1990513	CLOCK-BMAL transcription complex(GO:1990513)
0.4	3.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.4	3.9	GO:0000812	Swr1 complex(GO:0000812)
0.4	6.6	GO:0015030	Cajal body(GO:0015030)
0.4	2.3	GO:0070876	SOSS complex(GO:0070876)
0.4	13.8	GO:0032156	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.4	5.1	GO:0048179	activin receptor complex(GO:0048179)
0.4	1.1	GO:0033065	Rad51C-XRCC3 complex(GO:0033065)
0.3	2.0	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.3	2.0	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.3	3.0	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.3	1.3	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.3	3.9	GO:0016580	Sin3 complex(GO:0016580)
0.3	2.6	GO:0061700	GATOR2 complex(GO:0061700)
0.3	1.9	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.3	1.3	GO:0046695	SLIK (SAGA-like) complex(GO:0046695)
0.3	1.6	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	1.9	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3	1.4	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.3	1.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.3	5.5	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.3	0.8	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3	1.8	GO:0032797	SMN complex(GO:0032797)
0.3	2.8	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.3	14.7	GO:0031901	early endosome membrane(GO:0031901)
0.2	4.0	GO:0031209	SCAR complex(GO:0031209)
0.2	3.6	GO:0070187	telosome(GO:0070187)
0.2	2.3	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2	1.9	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	0.9	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2	3.4	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.2	1.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.2	5.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	1.3	GO:0005784	Sec61 translocon complex(GO:0005784)
0.2	3.6	GO:0000813	ESCRT I complex(GO:0000813)
0.2	2.9	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	1.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2	2.4	GO:0097431	mitotic spindle pole(GO:0097431)
0.2	1.8	GO:0032021	NELF complex(GO:0032021)
0.2	0.6	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2	1.8	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	2.0	GO:0071007	U2-type catalytic step 2 spliceosome(GO:0071007)
0.2	4.5	GO:0045180	basal cortex(GO:0045180)
0.2	1.3	GO:0045335	phagocytic vesicle(GO:0045335)
0.2	1.7	GO:0030904	retromer complex(GO:0030904)
0.2	4.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	14.0	GO:0005769	early endosome(GO:0005769)
0.2	0.9	GO:0070390	transcription export complex 2(GO:0070390)
0.2	19.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.2	6.9	GO:0016605	PML body(GO:0016605)
0.2	1.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.2	4.0	GO:0035102	PRC1 complex(GO:0035102)
0.2	3.2	GO:0005903	brush border(GO:0005903)
0.2	40.1	GO:0000323	lytic vacuole(GO:0000323)
0.2	1.2	GO:0001772	immunological synapse(GO:0001772)
0.2	0.5	GO:0010369	chromocenter(GO:0010369)
0.2	1.1	GO:0070652	HAUS complex(GO:0070652)
0.2	1.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	3.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	0.4	GO:0097361	CIA complex(GO:0097361)
0.1	1.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	2.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	1.5	GO:0034451	centriolar satellite(GO:0034451)
0.1	17.4	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1	0.7	GO:0000814	ESCRT II complex(GO:0000814)
0.1	0.5	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
0.1	1.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	3.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	8.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	1.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	1.8	GO:0071564	npBAF complex(GO:0071564)
0.1	2.2	GO:0032039	integrator complex(GO:0032039)
0.1	1.0	GO:0070822	Sin3-type complex(GO:0070822)
0.1	2.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	1.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	1.4	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	1.2	GO:0043296	apical junction complex(GO:0043296)
0.1	2.4	GO:0005921	gap junction(GO:0005921)
0.1	6.2	GO:0001726	ruffle(GO:0001726)
0.1	1.2	GO:0005682	U5 snRNP(GO:0005682)
0.1	2.4	GO:0000145	exocyst(GO:0000145)
0.1	6.2	GO:0030027	lamellipodium(GO:0030027)
0.1	3.4	GO:0072686	mitotic spindle(GO:0072686)
0.1	4.4	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1	4.4	GO:0000779	condensed chromosome, centromeric region(GO:0000779)
0.1	1.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.6	GO:0034399	nuclear periphery(GO:0034399)
0.1	4.9	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.6	GO:0016586	RSC complex(GO:0016586)
0.1	4.5	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1	1.0	GO:0005876	spindle microtubule(GO:0005876)
0.1	10.2	GO:0099572	postsynaptic specialization(GO:0099572)
0.1	1.8	GO:0071004	U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1	2.0	GO:0030496	midbody(GO:0030496)
0.1	3.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	4.7	GO:0016324	apical plasma membrane(GO:0016324)
0.1	0.9	GO:0043209	myelin sheath(GO:0043209)
0.1	66.8	GO:0005783	endoplasmic reticulum(GO:0005783)
0.1	0.4	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.1	6.5	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	1.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	5.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	3.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	2.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.6	GO:0017119	Golgi transport complex(GO:0017119)
0.0	31.6	GO:0005794	Golgi apparatus(GO:0005794)
0.0	4.3	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.3	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0	4.5	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	4.0	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	1.0	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	1.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.1	GO:0018444	translation release factor complex(GO:0018444)
0.0	0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	3.5	GO:0030425	dendrite(GO:0030425)
0.0	1.2	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.2	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.2	GO:0043204	perikaryon(GO:0043204)
0.0	0.8	GO:0008023	transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	8.4	GO:0008117	sphinganine-1-phosphate aldolase activity(GO:0008117)
2.0	5.9	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
1.6	4.9	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
1.3	3.8	GO:0009384	UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
1.2	13.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.1	3.3	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
1.0	6.2	GO:0008126	acetylesterase activity(GO:0008126)
1.0	20.9	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.0	3.9	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.0	2.9	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.9	2.8	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.9	3.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.9	2.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.9	9.1	GO:0015924	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.9	12.9	GO:0051117	ATPase binding(GO:0051117)
0.9	12.8	GO:2001069	glycogen binding(GO:2001069)
0.8	5.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.8	4.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.8	5.7	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.8	8.1	GO:0035198	miRNA binding(GO:0035198)
0.8	4.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8	3.0	GO:0033857	inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.7	2.2	GO:0004557	alpha-galactosidase activity(GO:0004557)
0.7	3.7	GO:1990757	anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.7	5.8	GO:0016530	metallochaperone activity(GO:0016530)
0.7	2.9	GO:0004373	glycogen (starch) synthase activity(GO:0004373)
0.7	2.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7	8.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7	3.4	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.7	2.0	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.7	2.7	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.6	1.9	GO:0003978	UDP-glucose 4-epimerase activity(GO:0003978)
0.6	2.5	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.6	6.7	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	3.0	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.6	6.5	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.6	2.4	GO:0031151	histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.6	2.3	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.6	4.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6	10.1	GO:0002039	p53 binding(GO:0002039)
0.6	2.8	GO:0001735	prenylcysteine oxidase activity(GO:0001735)
0.6	2.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.6	1.7	GO:0004394	heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.5	2.7	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.5	9.2	GO:0032190	acrosin binding(GO:0032190)
0.5	1.6	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.5	1.6	GO:0046403	polynucleotide 3'-phosphatase activity(GO:0046403)
0.5	3.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.5	5.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.5	6.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.5	1.5	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.5	3.9	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.5	1.4	GO:0032184	SUMO polymer binding(GO:0032184)
0.5	6.9	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.5	8.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.4	4.0	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4	3.6	GO:0017070	U6 snRNA binding(GO:0017070)
0.4	8.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4	3.5	GO:0048019	receptor antagonist activity(GO:0048019)
0.4	1.8	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4	2.2	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.4	3.4	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4	2.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4	3.4	GO:0008515	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4	5.0	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4	3.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	1.9	GO:0070412	R-SMAD binding(GO:0070412)
0.4	8.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.4	1.5	GO:0070182	DNA polymerase binding(GO:0070182)
0.4	5.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.4	2.6	GO:0070728	leucine binding(GO:0070728)
0.4	0.4	GO:0030547	receptor inhibitor activity(GO:0030547)
0.4	3.0	GO:0072518	Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.4	4.7	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4	3.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.4	11.0	GO:0042287	MHC protein binding(GO:0042287)
0.3	1.0	GO:0003919	FMN adenylyltransferase activity(GO:0003919)
0.3	2.7	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3	1.0	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	7.5	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.3	2.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.3	4.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.3	2.9	GO:0051920	peroxiredoxin activity(GO:0051920)
0.3	1.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	4.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	3.7	GO:0043495	protein anchor(GO:0043495)
0.3	1.5	GO:0008184	phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3	1.5	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.3	6.0	GO:0001671	ATPase activator activity(GO:0001671)
0.3	19.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.3	2.0	GO:0070888	E-box binding(GO:0070888)
0.3	5.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.3	0.9	GO:0016436	rRNA (uridine) methyltransferase activity(GO:0016436)
0.3	4.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.3	1.1	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
0.3	1.7	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3	10.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.3	1.4	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.3	3.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.3	1.4	GO:0001223	transcription coactivator binding(GO:0001223)
0.3	0.5	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.3	6.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.3	1.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.3	2.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.3	1.1	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.3	2.6	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3	6.5	GO:0005112	Notch binding(GO:0005112)
0.3	5.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.3	0.8	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	4.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487) nuclear import signal receptor activity(GO:0061608)
0.2	5.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2	1.9	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2	1.2	GO:0034046	poly(G) binding(GO:0034046)
0.2	0.7	GO:0070051	fibrinogen binding(GO:0070051)
0.2	0.9	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.2	2.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.2	3.1	GO:0070403	NAD+ binding(GO:0070403)
0.2	2.2	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.2	2.6	GO:0008422	beta-glucosidase activity(GO:0008422)
0.2	1.9	GO:0010436	beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2	1.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2	2.7	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2	1.3	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.2	5.0	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	4.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	3.6	GO:0045159	myosin II binding(GO:0045159)
0.2	3.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	2.7	GO:0050811	GABA receptor binding(GO:0050811)
0.2	3.2	GO:0052744	phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.2	0.6	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2	9.2	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	4.3	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.2	0.6	GO:1901612	cardiolipin binding(GO:1901612)
0.2	2.4	GO:0005158	insulin receptor binding(GO:0005158)
0.2	2.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.2	2.7	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	1.5	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2	1.7	GO:0008494	translation activator activity(GO:0008494)
0.2	1.6	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.2	2.3	GO:0005537	mannose binding(GO:0005537)
0.2	4.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	2.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	4.2	GO:0031267	small GTPase binding(GO:0031267)
0.2	3.1	GO:0004532	exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.2	2.6	GO:0031682	G-protein gamma-subunit binding(GO:0031682)
0.2	3.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	1.3	GO:0031419	cobalamin binding(GO:0031419)
0.2	3.4	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.2	2.8	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	4.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	1.7	GO:0005042	netrin receptor activity(GO:0005042)
0.2	0.5	GO:0009041	uridylate kinase activity(GO:0009041)
0.2	1.3	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.2	1.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.2	1.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.2	1.0	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2	3.9	GO:0015377	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2	0.6	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	0.9	GO:0004997	thyrotropin-releasing hormone receptor activity(GO:0004997)
0.2	4.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.2	4.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	7.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.2	1.8	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	4.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.4	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1	2.9	GO:0070411	I-SMAD binding(GO:0070411)
0.1	0.7	GO:0060182	apelin receptor activity(GO:0060182)
0.1	3.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	2.6	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	2.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	6.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.6	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	5.8	GO:0019902	phosphatase binding(GO:0019902)
0.1	3.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	1.4	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	21.9	GO:0060090	binding, bridging(GO:0060090)
0.1	1.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.0	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	6.7	GO:0030276	clathrin binding(GO:0030276)
0.1	0.8	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	7.3	GO:0019208	phosphatase regulator activity(GO:0019208)
0.1	0.8	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	6.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.7	GO:0032217	riboflavin transporter activity(GO:0032217)
0.1	0.9	GO:0034632	retinol transporter activity(GO:0034632)
0.1	0.4	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	2.2	GO:0035497	cAMP response element binding(GO:0035497)
0.1	6.7	GO:0017124	SH3 domain binding(GO:0017124)
0.1	2.6	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.6	GO:0004122	cystathionine beta-synthase activity(GO:0004122)
0.1	0.3	GO:0030882	lipid antigen binding(GO:0030882)
0.1	2.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	3.7	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1	3.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	4.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	4.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	3.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	1.6	GO:0008301	DNA binding, bending(GO:0008301)
0.1	1.4	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	1.5	GO:0005123	death receptor binding(GO:0005123)
0.1	3.2	GO:0000049	tRNA binding(GO:0000049)
0.1	5.8	GO:0004521	endoribonuclease activity(GO:0004521)
0.1	3.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.4	GO:0004998	transferrin receptor activity(GO:0004998)
0.1	4.6	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.4	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.1	0.7	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	12.3	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	0.7	GO:0043035	chromatin insulator sequence binding(GO:0043035)
0.1	1.7	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	2.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	1.8	GO:1901476	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1	0.8	GO:0031013	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1	0.4	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	2.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	0.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	1.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	5.4	GO:0032934	sterol binding(GO:0032934)
0.1	0.6	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	0.6	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	0.3	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	4.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.5	GO:1900750	oligopeptide binding(GO:1900750)
0.1	0.8	GO:0043142	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	1.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	1.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1	0.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	2.9	GO:0005109	frizzled binding(GO:0005109)
0.1	0.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	3.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	1.9	GO:0030165	PDZ domain binding(GO:0030165)
0.1	0.8	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.8	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1	1.8	GO:0005496	steroid binding(GO:0005496)
0.1	1.7	GO:0019213	deacetylase activity(GO:0019213)
0.1	0.4	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	2.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	0.9	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	1.9	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.1	1.6	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.1	1.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	0.8	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1	0.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.2	GO:2001070	starch binding(GO:2001070)
0.0	0.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	3.8	GO:0003724	RNA helicase activity(GO:0003724)
0.0	1.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0016521	pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0	13.3	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	2.3	GO:0042562	hormone binding(GO:0042562)
0.0	0.7	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	1.5	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	2.9	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.7	GO:0030515	snoRNA binding(GO:0030515)
0.0	3.0	GO:0019838	growth factor binding(GO:0019838)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.7	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	1.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.3	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.4	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	1.0	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	1.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.8	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	2.0	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	1.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	2.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	11.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	2.9	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0004067	asparaginase activity(GO:0004067)
0.0	0.7	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	1.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:1904680	peptide transporter activity(GO:0015197) oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916) peptide transmembrane transporter activity(GO:1904680)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	1.0	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.5	GO:0071949	FAD binding(GO:0071949)
0.0	0.0	GO:0070643	vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	1.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	1.2	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	8.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.6	3.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	6.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	3.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.4	3.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	7.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	7.0	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.4	17.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.4	2.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	12.8	PID AURORA B PATHWAY	Aurora B signaling
0.3	14.1	PID PLK1 PATHWAY	PLK1 signaling events
0.3	2.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	1.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.3	4.9	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	10.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	7.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	1.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.3	3.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.3	4.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.3	6.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	1.9	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	5.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	6.6	PID ATM PATHWAY	ATM pathway
0.2	0.4	ST STAT3 PATHWAY	STAT3 Pathway
0.2	5.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	1.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.2	5.3	PID ATR PATHWAY	ATR signaling pathway
0.2	2.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	2.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	2.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	2.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	4.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	5.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	6.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	2.8	PID MYC PATHWAY	C-MYC pathway
0.1	3.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	2.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	3.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	1.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	2.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	2.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	2.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	2.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.8	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	2.0	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	2.9	PID P73PATHWAY	p73 transcription factor network
0.1	0.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	8.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.7	14.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.7	6.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7	11.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6	2.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.6	7.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5	4.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.5	2.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.5	13.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.5	6.4	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.4	1.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.4	6.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.4	3.7	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.4	3.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.4	2.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	3.1	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.4	5.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.4	3.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.3	4.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	5.9	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.3	6.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.3	5.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.3	4.8	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.3	3.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	5.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	3.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	1.8	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2	7.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	5.9	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	1.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	2.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	2.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	2.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	2.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	1.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	2.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2	3.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2	1.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	2.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	1.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	5.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2	1.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	5.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	0.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	4.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	2.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.2	2.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.2	3.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	3.7	REACTOME KINESINS	Genes involved in Kinesins
0.2	0.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.2	1.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	1.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	1.9	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2	6.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	3.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	2.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	3.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.8	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	1.5	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.1	5.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	2.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	1.4	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	3.7	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.1	4.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	5.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	2.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	4.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.8	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.7	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	1.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	1.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	5.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	7.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.8	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	1.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.9	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	2.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	3.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME METABOLISM OF PROTEINS	Genes involved in Metabolism of proteins

Results for spi1a+spi1b

Z-value: 3.26

Motif logo

Transcription factors associated with spi1a+spi1b

Activity-expression correlation:

Activity profile of spi1a+spi1b motif

Sorted Z-values of spi1a+spi1b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of spi1a+spi1b

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: