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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Z-value: 1.39

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Transcription factors associated with sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Gene Symbol Gene ID Gene Info
ENSDARG00000011870 sp8 transcription factor a
ENSDARG00000056666 sp8 transcription factor b
ENSDARG00000005186 sp4 transcription factor
ENSDARG00000001549 sp3a transcription factor
ENSDARG00000005846 Sp5 transcription factor b
ENSDARG00000079922 Kruppel-like factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp8adr11_v1_chr19_-_2317558_23175580.881.2e-06Click!
sp3adr11_v1_chr9_+_2762270_27624150.832.0e-05Click!
klf4dr11_v1_chr21_-_435466_435466-0.762.3e-04Click!
sp4dr11_v1_chr19_+_2546775_25467750.753.4e-04Click!
FO704755.1dr11_v1_chr6_+_3809346_3809346-0.381.2e-01Click!
sp8bdr11_v1_chr16_+_19536614_19536761-0.272.9e-01Click!

Activity profile of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Sorted Z-values of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_410728 7.20 ENSDART00000151255
tripartite motif containing 36
chr7_+_1473929 6.02 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr2_+_25658112 5.69 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr22_+_835728 5.31 ENSDART00000003325
DENN/MADD domain containing 2Db
chr10_-_34002185 5.20 ENSDART00000046599
zygote arrest 1-like
chr23_-_31645760 5.11 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr16_-_7793457 5.09 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr2_+_25657958 4.97 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr19_+_26340736 4.94 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr20_-_182841 4.94 ENSDART00000064546
si:ch211-241j12.3
chr18_-_127558 4.88 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr19_-_11031145 4.86 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tropomyosin 3
chr7_+_38349667 4.79 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr3_-_40054615 4.77 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr12_+_46634736 4.55 ENSDART00000008009
tripartite motif containing 16
chr8_-_410199 4.17 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr18_-_127873 4.09 ENSDART00000148490
transient receptor potential cation channel, subfamily M, member 7
chr17_-_18898115 3.97 ENSDART00000028044
galactosylceramidase b
chr5_-_13086616 3.80 ENSDART00000051664
yippee-like 1
chr11_-_34577034 3.75 ENSDART00000133302
ENSDART00000184367
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr2_+_68789 3.70 ENSDART00000058569
claudin 1
chr21_-_32060993 3.68 ENSDART00000131651
si:ch211-160j14.2
chr16_+_53455638 3.62 ENSDART00000045792
ENSDART00000154189
RNA binding motif protein 24b
chr10_-_41352502 3.62 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr17_+_25856671 3.60 ENSDART00000064817
WAPL cohesin release factor a
chr3_-_50998577 3.45 ENSDART00000157735
CDC42 effector protein (Rho GTPase binding) 4a
chr8_+_47219107 3.44 ENSDART00000146018
ENSDART00000075068
methylenetetrahydrofolate reductase (NAD(P)H)
chr12_-_37449396 3.43 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr3_+_32410746 3.42 ENSDART00000025496
RAS related
chr7_+_40083601 3.30 ENSDART00000099046
zgc:112356
chr10_-_44017642 3.29 ENSDART00000135240
ENSDART00000014669
acyl-CoA dehydrogenase short chain
chr21_-_43398122 3.28 ENSDART00000050533
cyclin I family, member 2
chr19_-_867071 3.20 ENSDART00000122257
eomesodermin homolog a
chr21_-_13856689 3.14 ENSDART00000102197
family with sequence similarity 129, member Ba
chr7_+_55518519 3.14 ENSDART00000098476
ENSDART00000149915
chromatin licensing and DNA replication factor 1
chr1_-_34450784 3.12 ENSDART00000140515
LIM domain 7b
chr5_-_69482891 3.08 ENSDART00000109487

chr5_-_23696926 3.08 ENSDART00000021462
ring finger protein 128a
chr3_-_15470944 3.01 ENSDART00000185302
spinster homolog 1 (Drosophila)
chr1_-_34450622 2.97 ENSDART00000083736
LIM domain 7b
chr6_-_7776612 2.92 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr1_+_45707219 2.92 ENSDART00000143363
si:ch211-214c7.4
chr10_-_2942900 2.84 ENSDART00000002622
occludin a
chr20_+_46741074 2.83 ENSDART00000145294
si:ch211-57i17.1
chr7_-_19332293 2.79 ENSDART00000169668
ENSDART00000137575
ENSDART00000090406
dedicator of cytokinesis 11
chr25_+_3104959 2.78 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr19_+_46113828 2.77 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr21_-_43398457 2.76 ENSDART00000166530
cyclin I family, member 2
chr19_-_6193448 2.73 ENSDART00000151405
Ets2 repressor factor
chr22_+_883678 2.73 ENSDART00000140588
serine/threonine kinase 38b
chr6_+_41503854 2.72 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr5_+_66132394 2.71 ENSDART00000073892
zgc:114041
chr14_+_7048930 2.68 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr22_+_11756040 2.68 ENSDART00000105808
keratin 97
chr16_+_30002605 2.66 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr24_+_35387517 2.65 ENSDART00000058571
snail family zinc finger 2
chr23_-_452365 2.65 ENSDART00000146776
tetraspanin 2b
chr23_+_12160900 2.59 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr17_+_51746830 2.54 ENSDART00000184230
ornithine decarboxylase 1
chr2_-_11027258 2.54 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
single stranded DNA binding protein 3a
chr9_-_11263228 2.52 ENSDART00000113847
chondroitin polymerizing factor a
chr10_+_39199547 2.50 ENSDART00000075943
etoposide induced 2.4
chr2_-_39675829 2.49 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr22_-_38459316 2.47 ENSDART00000149683
ENSDART00000098461
protein tyrosine kinase 7a
chr15_+_46344655 2.45 ENSDART00000155893
si:ch1073-340i21.2
chr2_-_47620806 2.44 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr19_-_6193067 2.42 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr2_+_35880600 2.42 ENSDART00000004277
laminin, gamma 1
chr23_-_10177442 2.39 ENSDART00000144280
ENSDART00000129044
keratin 5
chr19_-_2029777 2.37 ENSDART00000128639

chr22_+_336256 2.36 ENSDART00000019155
B-cell translocation gene 2
chr5_+_4533244 2.33 ENSDART00000158826
Danio rerio thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 (LOC561325), mRNA.
chr2_+_35603637 2.31 ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr20_+_51061695 2.29 ENSDART00000134416
im:7140055
chr23_+_2825940 2.29 ENSDART00000135781
phospholipase C, gamma 1
chr25_+_6122823 2.26 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr20_-_14781904 2.26 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
SUN domain containing ossification factor
chr22_-_20924747 2.26 ENSDART00000185845
ENSDART00000179672
elongation factor RNA polymerase II
chr22_-_20924564 2.26 ENSDART00000100642
ENSDART00000032770
elongation factor RNA polymerase II
chr4_-_4612116 2.25 ENSDART00000130601
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr3_-_32362872 2.24 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr8_+_2656231 2.21 ENSDART00000160833
family with sequence similarity 102, member Aa
chr16_+_43077909 2.21 ENSDART00000014140
RUN domain containing 3b
chr25_+_7492663 2.20 ENSDART00000166496
catalase
chr3_+_31925067 2.20 ENSDART00000127330
ENSDART00000055279
small nuclear ribonucleoprotein 70 (U1)
chr9_-_34269066 2.20 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr23_+_30730121 2.16 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr13_+_421231 2.15 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr22_-_10539180 2.12 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr7_+_67325933 2.10 ENSDART00000170575
ENSDART00000183342
nuclear factor of activated T cells 5b
chr4_+_9011825 2.07 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr19_+_47290287 2.06 ENSDART00000078382
thiopurine S-methyltransferase, tandem duplicate 1
chr8_-_4618653 2.05 ENSDART00000025535
septin 5a
chr13_+_47821524 2.05 ENSDART00000109978
zinc finger CCCH-type containing 6
chr2_-_32513538 2.05 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr4_+_9011448 2.04 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr22_-_10752471 2.04 ENSDART00000081191
SAS-6 centriolar assembly protein
chr21_-_14692119 2.03 ENSDART00000123047
euchromatic histone-lysine N-methyltransferase 1b
chr6_+_3334392 2.03 ENSDART00000133707
ENSDART00000130879
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr13_+_42309688 2.02 ENSDART00000158367
insulin-degrading enzyme
chr22_+_24559947 2.01 ENSDART00000169847
WD repeat domain 47b
chr9_-_32343673 2.00 ENSDART00000078499
raftlin family member 2
chr13_-_18691041 2.00 ENSDART00000057867
sideroflexin 3
chr9_-_54840124 1.99 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr2_-_37478418 1.98 ENSDART00000146103
death-associated protein kinase 3
chr23_-_10745288 1.98 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr19_+_43341115 1.97 ENSDART00000145846
ENSDART00000102384
sestrin 2
chr23_-_17429775 1.97 ENSDART00000043076
pancreatic progenitor cell differentiation and proliferation factor b
chr21_-_39024754 1.96 ENSDART00000056878
tnf receptor-associated factor 4b
chr8_-_53044300 1.94 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr22_-_6562618 1.94 ENSDART00000106100
zgc:171490
chr11_-_12158412 1.93 ENSDART00000147670
aminopeptidase puromycin sensitive
chr15_-_45538773 1.91 ENSDART00000113494
Mab-21 domain containing 2
chr12_+_48340133 1.91 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr3_+_22984098 1.91 ENSDART00000043190
LSM12 homolog a
chr18_-_22094102 1.89 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr19_+_43341424 1.89 ENSDART00000134815
sestrin 2
chr19_+_46237665 1.88 ENSDART00000159391
vacuolar protein sorting 28 (yeast)
chr4_-_5018705 1.87 ENSDART00000154025
striatin interacting protein 2
chr10_-_244745 1.87 ENSDART00000136551
kelch-like family member 35
chr9_+_30421489 1.85 ENSDART00000145025
ENSDART00000132058
zgc:113314
chr19_+_9111550 1.85 ENSDART00000088336
SET domain, bifurcated 1a
chr2_+_59015878 1.85 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr24_+_39277043 1.84 ENSDART00000165458
si:ch73-103b11.2
chr16_-_31351419 1.84 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr10_+_6383270 1.84 ENSDART00000170548
zgc:114200
chr22_-_21676364 1.83 ENSDART00000183668
transducin like enhancer of split 2b
chr17_+_17804752 1.82 ENSDART00000123350
serine palmitoyltransferase, long chain base subunit 2a
chr15_+_29024895 1.82 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr15_+_46853252 1.79 ENSDART00000186040
zgc:153039
chr13_+_49727333 1.78 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr4_-_5019113 1.77 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr16_-_21489514 1.77 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr18_-_5248365 1.77 ENSDART00000082506
ENSDART00000082504
ENSDART00000097960
myelin expression factor 2
chr10_+_22034477 1.76 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr3_-_15131438 1.76 ENSDART00000131720
exportin 6
chr2_+_1988036 1.75 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr8_-_32385989 1.74 ENSDART00000143716
ENSDART00000098850
lipase, endothelial
chr10_-_35257458 1.74 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr24_-_36238054 1.72 ENSDART00000155725
transmembrane protein 241
chr20_-_23254876 1.71 ENSDART00000141510
OCIA domain containing 1
chr23_+_35426404 1.70 ENSDART00000164658
si:ch211-225h24.2
chr7_-_64971839 1.68 ENSDART00000164682
SIN3-HDAC complex associated factor, like
chr14_-_24277805 1.68 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr21_+_21279159 1.67 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr9_+_4378153 1.66 ENSDART00000191264
ENSDART00000182384
kalirin RhoGEF kinase a
chr7_-_4125021 1.66 ENSDART00000167182
ENSDART00000173696
zgc:55733
chr22_+_30184039 1.66 ENSDART00000049075
adducin 3 (gamma) a
chr2_-_37134169 1.65 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
ELAV like RNA binding protein 1a
chr15_-_25094026 1.65 ENSDART00000129154
exonuclease 5
chr8_+_23165749 1.63 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr9_-_264173 1.63 ENSDART00000166231
ENSDART00000165585
poly(rC) binding protein 2
chr10_-_32851847 1.61 ENSDART00000134255
tripartite motif containing 37
chr4_+_2637947 1.61 ENSDART00000130623
dihydrouridine synthase 4-like (S. cerevisiae)
chr7_+_71764883 1.61 ENSDART00000166865
myosin, light chain 12, genome duplicate 1
chr15_+_29025090 1.61 ENSDART00000131755
si:ch211-137a8.2
chr24_-_28333029 1.60 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr18_+_3634652 1.60 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr7_-_30492261 1.60 ENSDART00000173954
ADAM metallopeptidase domain 10a
chr6_+_32326074 1.60 ENSDART00000042134
ENSDART00000181177
dedicator of cytokinesis 7
chr2_-_21438492 1.60 ENSDART00000046098
phospholipase C, delta 1b
chr19_+_30867845 1.60 ENSDART00000047461
major facilitator superfamily domain containing 2ab
chr16_-_8120203 1.59 ENSDART00000193430
SNF related kinase a
chr20_-_2361226 1.57 ENSDART00000172130
si:ch73-18b11.1
chr5_+_43458304 1.57 ENSDART00000051114
Rho-related BTB domain containing 2a
chr15_-_23942861 1.57 ENSDART00000002824
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr3_+_18437397 1.56 ENSDART00000136243
ENSDART00000184882
ENSDART00000135470
TBC1 domain family, member 16
chr3_+_24595922 1.56 ENSDART00000169405
si:dkey-68o6.5
chr3_-_6417328 1.55 ENSDART00000160979
Jupiter microtubule associated homolog 1b
chr12_-_3053873 1.54 ENSDART00000023796
ENSDART00000137148
dicarbonyl/L-xylulose reductase
chr14_+_22132388 1.54 ENSDART00000109065
cyclin G1
chr21_+_6197223 1.53 ENSDART00000147716
si:dkey-93m18.3
chr1_+_604127 1.53 ENSDART00000133165
junctional adhesion molecule 2a
chr14_+_30291611 1.53 ENSDART00000173004
microtubule associated tumor suppressor 1a
chr1_+_44196236 1.52 ENSDART00000179560
ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr9_+_55536005 1.52 ENSDART00000192364
matrix-remodelling associated 5b
chr1_+_24469313 1.51 ENSDART00000176581
family with sequence similarity 160, member A1a
chr13_-_17860307 1.50 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr3_+_51684963 1.50 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr14_-_237130 1.50 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr18_+_46151505 1.50 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr19_-_18135724 1.50 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr7_-_59159253 1.49 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr21_+_31253048 1.48 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
argininosuccinate lyase
chr20_+_4157815 1.48 ENSDART00000113132
glyceronephosphate O-acyltransferase
chr23_-_37085547 1.48 ENSDART00000144333
integrator complex subunit 11
chr9_+_50110763 1.48 ENSDART00000162990
cordon-bleu WH2 repeat protein-like 1b
chr19_-_31686252 1.47 ENSDART00000131721
RHO family interacting cell polarization regulator 2
chr6_-_17849786 1.46 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr25_+_21098675 1.46 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr8_-_2616326 1.46 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr15_-_19128705 1.46 ENSDART00000152428
Rho GTPase activating protein 32a
chr7_-_58098814 1.46 ENSDART00000147287
ENSDART00000043984
ankyrin 2b, neuronal
chr15_-_25093680 1.45 ENSDART00000062695
exonuclease 5
chr7_+_71764665 1.45 ENSDART00000171996
myosin, light chain 12, genome duplicate 1
chr12_-_4475890 1.44 ENSDART00000092492
si:ch211-173d10.1
chr20_-_52928541 1.44 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr7_-_30492018 1.44 ENSDART00000099639
ENSDART00000162705
ENSDART00000173663
ADAM metallopeptidase domain 10a
chr7_-_38714544 1.43 ENSDART00000139382
F-box protein 3
chr3_-_52899394 1.42 ENSDART00000128223
coiled-coil-helix-coiled-coil-helix domain containing 5

Network of associatons between targets according to the STRING database.

First level regulatory network of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.6 6.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
1.2 3.6 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.2 3.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.1 3.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
1.0 5.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.9 2.7 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.8 3.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.8 2.3 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.8 4.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.7 2.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.7 6.9 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.7 2.0 GO:1903792 negative regulation of anion transport(GO:1903792)
0.7 2.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.6 0.6 GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.6 2.9 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.6 2.3 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.6 2.2 GO:0034969 histone arginine methylation(GO:0034969)
0.5 2.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.5 3.8 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.5 7.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.5 2.1 GO:0052746 inositol phosphorylation(GO:0052746)
0.5 2.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.5 2.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.5 4.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.5 1.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.5 1.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.5 1.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.5 2.3 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.4 3.5 GO:0071295 cellular response to nutrient(GO:0031670) cellular response to vitamin(GO:0071295)
0.4 1.8 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.4 0.9 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.3 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.4 2.9 GO:0040016 embryonic cleavage(GO:0040016)
0.4 1.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 1.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 5.4 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.4 1.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 1.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 1.4 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 5.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 1.0 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 1.6 GO:0045056 transcytosis(GO:0045056)
0.3 2.5 GO:2000095 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3 3.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.3 2.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 1.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.3 1.1 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.3 1.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 0.8 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 1.4 GO:0034505 tooth mineralization(GO:0034505)
0.3 3.3 GO:0003139 secondary heart field specification(GO:0003139)
0.3 1.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.3 3.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.0 GO:0021557 oculomotor nerve development(GO:0021557)
0.3 3.0 GO:0090398 cellular senescence(GO:0090398)
0.2 1.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 2.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 3.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.9 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 2.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 1.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 3.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 1.9 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.0 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.2 0.8 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.8 GO:0007220 Notch receptor processing(GO:0007220)
0.2 1.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.6 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.2 1.0 GO:0046416 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.2 0.4 GO:0048478 replication fork protection(GO:0048478)
0.2 4.2 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 1.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 2.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 1.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 1.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 0.5 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 0.9 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 2.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.3 GO:0038202 TORC1 signaling(GO:0038202)
0.2 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.2 0.9 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.2 1.3 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.3 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.2 1.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 0.5 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.2 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 1.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 5.1 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 1.6 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.6 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 2.2 GO:0046688 response to copper ion(GO:0046688)
0.1 3.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 2.1 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.4 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 6.2 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.5 GO:0008356 asymmetric cell division(GO:0008356)
0.1 1.0 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.5 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 2.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.4 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.9 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 1.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 3.2 GO:0016180 snRNA processing(GO:0016180)
0.1 1.1 GO:0043144 snoRNA processing(GO:0043144)
0.1 1.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.7 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.7 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 2.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.1 0.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.4 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 3.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 11.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 0.8 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.3 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 1.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.3 GO:0009303 rRNA transcription(GO:0009303)
0.1 3.0 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.4 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.5 GO:1902946 protein localization to early endosome(GO:1902946)
0.1 1.4 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.7 GO:1903578 regulation of oxidative phosphorylation(GO:0002082) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.9 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 1.1 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 1.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.4 GO:0071800 podosome assembly(GO:0071800)
0.1 1.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.2 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.6 GO:0001840 neural plate development(GO:0001840)
0.1 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 3.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.2 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.4 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.4 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.3 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 1.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.9 GO:0060541 respiratory system development(GO:0060541)
0.1 0.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 4.8 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 1.4 GO:0001841 neural tube formation(GO:0001841)
0.0 0.5 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 2.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 2.7 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 2.4 GO:0030217 T cell differentiation(GO:0030217)
0.0 2.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.3 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.0 1.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 2.0 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.6 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.4 GO:0030104 water homeostasis(GO:0030104)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.4 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.0 GO:0070831 basement membrane assembly(GO:0070831)
0.0 1.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 2.7 GO:0051225 spindle assembly(GO:0051225)
0.0 3.2 GO:0042552 myelination(GO:0042552)
0.0 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.4 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.0 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.5 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 4.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 7.9 GO:0006644 phospholipid metabolic process(GO:0006644)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 1.0 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 1.0 GO:0048884 neuromast development(GO:0048884)
0.0 0.7 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.3 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 2.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0006210 thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.9 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:0048785 hatching gland development(GO:0048785)
0.0 0.2 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.0 3.4 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0032231 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.0 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0001736 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 0.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0038034 signal transduction in absence of ligand(GO:0038034) negative regulation of mitotic nuclear division(GO:0045839) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.1 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.5 GO:0006821 chloride transport(GO:0006821)
0.0 0.4 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.0 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 2.0 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.0 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.6 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 1.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0010573 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.0 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 1.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.4 GO:0006887 exocytosis(GO:0006887)
0.0 2.2 GO:0032259 methylation(GO:0032259)
0.0 0.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271) DNA strand elongation(GO:0022616)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098536 deuterosome(GO:0098536)
0.6 4.6 GO:0061700 GATOR2 complex(GO:0061700)
0.5 0.5 GO:0071564 npBAF complex(GO:0071564)
0.5 2.0 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.5 3.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.3 1.4 GO:0035339 SPOTS complex(GO:0035339)
0.3 2.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 2.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 1.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 2.2 GO:0035517 PR-DUB complex(GO:0035517)
0.3 0.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.5 GO:0001650 fibrillar center(GO:0001650)
0.2 1.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 2.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.2 1.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.0 GO:0030904 retromer complex(GO:0030904)
0.2 1.5 GO:0031931 TORC1 complex(GO:0031931)
0.2 3.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 3.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 2.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 2.0 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.8 GO:0035101 FACT complex(GO:0035101)
0.2 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.7 GO:0045095 keratin filament(GO:0045095)
0.2 2.9 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 6.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.7 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.4 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 1.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.4 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.6 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 3.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.4 GO:0030315 T-tubule(GO:0030315)
0.1 0.7 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 4.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 10.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 4.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 6.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 1.6 GO:0071565 nBAF complex(GO:0071565)
0.1 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0001772 immunological synapse(GO:0001772)
0.1 1.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 3.3 GO:0005770 late endosome(GO:0005770)
0.0 1.0 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 4.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 9.1 GO:0005764 lysosome(GO:0005764)
0.0 5.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0032806 holo TFIIH complex(GO:0005675) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.3 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 10.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 4.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 5.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.8 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.9 2.8 GO:1990715 mRNA CDS binding(GO:1990715)
0.9 2.8 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.8 3.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.8 3.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 2.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.7 2.2 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.5 7.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 3.8 GO:0070728 leucine binding(GO:0070728)
0.5 5.1 GO:0035198 miRNA binding(GO:0035198)
0.5 1.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.4 2.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.4 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 1.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.4 2.6 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.4 1.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 2.9 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.3 3.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.0 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.3 5.4 GO:0045159 myosin II binding(GO:0045159)
0.3 1.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.3 0.9 GO:0034618 arginine binding(GO:0034618)
0.3 0.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 1.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.3 2.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 0.8 GO:0031701 angiotensin receptor binding(GO:0031701)
0.3 0.8 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 2.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.3 3.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 2.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 2.2 GO:0004096 catalase activity(GO:0004096)
0.2 1.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.5 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.2 1.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 2.0 GO:0043515 kinetochore binding(GO:0043515)
0.2 3.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 2.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 1.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 2.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.0 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 1.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 3.0 GO:2001069 glycogen binding(GO:2001069)
0.2 1.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 1.1 GO:0019107 myristoyltransferase activity(GO:0019107)
0.2 0.7 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 2.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 1.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 4.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 4.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 5.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.4 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.4 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 1.0 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.0 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 3.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.9 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.0 GO:0002039 p53 binding(GO:0002039)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 3.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 2.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 3.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.3 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 1.7 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0008061 chitin binding(GO:0008061)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 6.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.5 GO:0019894 kinesin binding(GO:0019894)
0.1 3.6 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.8 GO:0050661 NADP binding(GO:0050661)
0.0 1.4 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 6.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.9 GO:0017069 snRNA binding(GO:0017069)
0.0 0.8 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.0 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.9 GO:0010181 FMN binding(GO:0010181)
0.0 1.2 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 11.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 1.4 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 5.7 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.8 GO:0019212 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 2.5 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 4.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 1.8 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 6.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 14.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.6 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 10.7 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.1 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 3.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 4.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 2.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 9.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.5 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 3.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 9.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.4 PID ATM PATHWAY ATM pathway
0.1 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.6 5.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 2.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 3.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 4.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 5.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 7.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.3 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 3.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 4.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 1.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.5 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 3.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME SEMAPHORIN INTERACTIONS Genes involved in Semaphorin interactions
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening