Project
PRJNA438478: RNAseq of wild type zebrafish germline
Navigation
Downloads
Results for sp3b
Z-value: 0.83
Motif logo
Transcription factors associated with sp3b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| sp3b | dr11_v1_chr6_-_10728057_10728057 | -0.89 | 8.2e-07 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_44924289 Show fit | 4.57 |
ENSDART00000171267
|
tubulin, alpha 7 like |
|
| chr10_-_641609 Show fit | 4.13 |
ENSDART00000041236
|
regulatory factor X, 3 (influences HLA class II expression) |
|
| chr6_-_60104628 Show fit | 4.03 |
ENSDART00000057463
ENSDART00000169188 |
prostate transmembrane protein, androgen induced 1 |
|
| chr20_-_147574 Show fit | 3.35 |
ENSDART00000104762
ENSDART00000131635 |
solute carrier family 16 (aromatic amino acid transporter), member 10 |
|
| chr2_-_44183451 Show fit | 3.32 |
ENSDART00000111246
|
cell adhesion molecule 3 |
|
| chr7_-_16598212 Show fit | 3.10 |
ENSDART00000128488
|
E2F transcription factor 8 |
|
| chr2_-_44183613 Show fit | 2.85 |
ENSDART00000079596
|
cell adhesion molecule 3 |
|
| chr6_+_475264 Show fit | 2.68 |
ENSDART00000193615
|
|
|
| chr3_-_16227683 Show fit | 2.61 |
ENSDART00000111707
|
calcium channel, voltage-dependent, beta 1 subunit |
|
| chr15_+_19838458 Show fit | 2.27 |
ENSDART00000101204
|
activated leukocyte cell adhesion molecule b |
Network of associatons between targets according to the STRING database.
First level regulatory network of sp3b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.8 | GO:0033301 | cell cycle comprising mitosis without cytokinesis(GO:0033301) |
| 0.2 | 4.1 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.6 | 4.0 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.1 | 3.8 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.6 | 2.9 | GO:0071071 | heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 0.0 | 2.8 | GO:0001708 | cell fate specification(GO:0001708) |
| 0.0 | 2.7 | GO:0000956 | nuclear-transcribed mRNA catabolic process(GO:0000956) |
| 0.3 | 2.3 | GO:0021885 | forebrain cell migration(GO:0021885) |
| 0.2 | 2.1 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 2.1 | GO:0006096 | glycolytic process(GO:0006096) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.5 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 4.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 3.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 2.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 2.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.3 | 2.0 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.2 | 2.0 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 1.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.6 | 1.7 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.5 | 4.4 | GO:0001130 | bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217) |
| 0.8 | 4.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 3.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.8 | 3.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.4 | 2.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 2.7 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 2.3 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.2 | 2.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 2.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 2.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 2.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.7 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 1.6 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.8 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 3.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.2 | 2.1 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 2.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 2.0 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.2 | 1.7 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.7 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 1.7 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.1 | 1.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |