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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox7

Z-value: 0.29

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Transcription factors associated with sox7

Gene Symbol Gene ID Gene Info
sox7
ENSDARG00000030125 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox7dr11_v1_chr20_+_19066858_190668580.625.7e-03Click!

Activity profile of sox7 motif

Sorted Z-values of sox7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_44356707 0.71 ENSDART00000165219
srsf7b
serine/arginine-rich splicing factor 7b
chr11_+_44356504 0.69 ENSDART00000160678
srsf7b
serine/arginine-rich splicing factor 7b
chr20_-_4766645 0.69 ENSDART00000147071
ENSDART00000152398
ak7a
adenylate kinase 7a
chr24_+_35787629 0.66 ENSDART00000136721
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr2_-_24898226 0.64 ENSDART00000134936
si:dkey-149i17.9
si:dkey-149i17.9
chr17_-_46817295 0.55 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr10_+_439692 0.53 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr7_-_52388734 0.50 ENSDART00000174186
wdr93
WD repeat domain 93
chr14_+_6546516 0.50 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr17_-_46933567 0.49 ENSDART00000157274
pimr25
Pim proto-oncogene, serine/threonine kinase, related 25
chr11_-_41779281 0.42 ENSDART00000109204
megf6b
multiple EGF-like-domains 6b
chr15_-_21692630 0.38 ENSDART00000039865
sdhdb
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr22_-_29204960 0.38 ENSDART00000131386
pvalb7
parvalbumin 7
chr6_-_16868834 0.37 ENSDART00000156503
pimr41
Pim proto-oncogene, serine/threonine kinase, related 41
chr6_-_17266221 0.37 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr20_+_38276690 0.36 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr1_-_49649122 0.36 ENSDART00000134399
slkb
STE20-like kinase b
chr3_-_6709938 0.35 ENSDART00000172196
atg4db
autophagy related 4D, cysteine peptidase b
chr15_-_35252522 0.34 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr6_-_16735402 0.34 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr8_-_48741106 0.34 ENSDART00000164203
pimr180
Pim proto-oncogene, serine/threonine kinase, related 180
chr16_+_10777116 0.33 ENSDART00000190902
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr6_-_17052116 0.31 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr9_+_11587629 0.31 ENSDART00000102508
ENSDART00000146585
si:dkey-69o16.5
si:dkey-69o16.5
chr14_+_8725216 0.29 ENSDART00000157630
pimr57
Pim proto-oncogene, serine/threonine kinase, related 57
chr9_-_23033818 0.27 ENSDART00000022392
rnd3b
Rho family GTPase 3b
chr11_+_6010177 0.27 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr5_-_57169604 0.27 ENSDART00000136232
si:dkey-79c1.1
si:dkey-79c1.1
chr9_+_32860345 0.26 ENSDART00000121751
si:dkey-145p14.5
si:dkey-145p14.5
chr7_+_18176162 0.26 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr15_-_23647078 0.26 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr12_+_26621906 0.25 ENSDART00000158440
ENSDART00000046959
arhgap12b
Rho GTPase activating protein 12b
chr6_+_49081141 0.25 ENSDART00000131080
ENSDART00000050000
tshba
thyroid stimulating hormone, beta subunit, a
chr16_+_46111849 0.24 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr6_-_17179637 0.23 ENSDART00000153710
pimr19
Pim proto-oncogene, serine/threonine kinase, related 19
chr22_+_29204885 0.23 ENSDART00000133409
ENSDART00000059820
ncf4
neutrophil cytosolic factor 4
chr5_-_67911111 0.23 ENSDART00000051833
gsx1
GS homeobox 1
chr22_-_16658996 0.22 ENSDART00000138429
si:dkey-38n4.2
si:dkey-38n4.2
chr21_+_19062124 0.22 ENSDART00000134746
rpl17
ribosomal protein L17
chr25_-_17579701 0.21 ENSDART00000073684
mmp15a
matrix metallopeptidase 15a
chr6_-_16804001 0.21 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr22_-_29205327 0.21 ENSDART00000183161
ENSDART00000189515
pvalb7
parvalbumin 7
chr4_+_47178124 0.21 ENSDART00000170816
si:dkey-26m3.2
si:dkey-26m3.2
chr3_+_52737565 0.20 ENSDART00000108639
gmip
GEM interacting protein
chr5_+_34982318 0.19 ENSDART00000160504
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr19_+_10860485 0.18 ENSDART00000169962
si:ch73-347e22.4
si:ch73-347e22.4
chr20_+_50956369 0.16 ENSDART00000170854
gphnb
gephyrin b
chr6_-_16948040 0.15 ENSDART00000156433
pimr30
Pim proto-oncogene, serine/threonine kinase, related 30
chr22_-_29191152 0.14 ENSDART00000132702
pvalb7
parvalbumin 7
chr17_-_22010668 0.14 ENSDART00000031998
slc22a7b.1
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr9_+_32859967 0.14 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr4_-_77216726 0.13 ENSDART00000099943
psmb10
proteasome subunit beta 10
chr1_+_36674584 0.13 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr10_+_27068251 0.12 ENSDART00000012717
ehd1b
EH-domain containing 1b
chr16_+_27345383 0.11 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr18_-_18524624 0.11 ENSDART00000157834
lonp2
lon peptidase 2, peroxisomal
chr20_-_42534153 0.11 ENSDART00000061122
rfx6
regulatory factor X, 6
chr5_+_65871688 0.09 ENSDART00000175217
FAM163B (1 of many)
family with sequence similarity 163 member B
chr16_+_40024883 0.09 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr14_+_45645024 0.09 ENSDART00000168278
si:ch211-276i12.4
si:ch211-276i12.4
chr8_-_20291922 0.08 ENSDART00000148304
myo1f
myosin IF
chr19_+_5480327 0.08 ENSDART00000148794
jupb
junction plakoglobin b
chr7_+_18878973 0.07 ENSDART00000037846
focad
focadhesin
chr13_+_835390 0.07 ENSDART00000171329
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr2_-_27385934 0.06 ENSDART00000139886
toe1
target of EGR1, exonuclease
chr4_+_33461796 0.06 ENSDART00000150445
si:dkey-247i3.1
si:dkey-247i3.1
chr22_+_2239254 0.05 ENSDART00000131396
ENSDART00000135320
znf1144
zinc finger protein 1144
chr22_-_26558166 0.05 ENSDART00000111125
glis2a
GLIS family zinc finger 2a
chr2_-_45504798 0.05 ENSDART00000131412
gpsm2
G protein signaling modulator 2
chr8_+_2787042 0.04 ENSDART00000155275
sh3glb2a
SH3-domain GRB2-like endophilin B2a
chr21_-_18932761 0.04 ENSDART00000140129
med15
mediator complex subunit 15
chr10_-_23379146 0.04 ENSDART00000056369
cadm2a
cell adhesion molecule 2a
chr3_-_27065477 0.04 ENSDART00000185660
atf7ip2
activating transcription factor 7 interacting protein 2
chr2_-_24996441 0.04 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr2_+_6991208 0.03 ENSDART00000182239
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr20_+_10727022 0.03 ENSDART00000104185
si:ch211-182e10.4
si:ch211-182e10.4
chr4_-_71311438 0.02 ENSDART00000168021
si:dkeyp-123a12.2
si:dkeyp-123a12.2
chr12_+_4114401 0.02 ENSDART00000025912
si:dkey-32n7.4
si:dkey-32n7.4
chr21_+_20903244 0.02 ENSDART00000186193
c7b
complement component 7b
chr12_-_4540564 0.02 ENSDART00000106566
CABZ01030107.1

chr25_-_7999756 0.02 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr21_+_31811202 0.02 ENSDART00000189846
si:ch211-12m10.1
si:ch211-12m10.1
chr12_+_30109698 0.02 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr16_-_31985965 0.01 ENSDART00000161944
si:dkey-40m6.14
si:dkey-40m6.14
chr1_-_10669436 0.01 ENSDART00000152421
si:dkey-31e10.5
si:dkey-31e10.5
chr20_+_37294112 0.01 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr7_-_35083184 0.01 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agrp
agouti related neuropeptide
chr10_-_7913591 0.01 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr5_-_12824607 0.01 ENSDART00000190310
p2rx2
purinergic receptor P2X, ligand-gated ion channel, 2
chr22_+_5682635 0.00 ENSDART00000140680
ENSDART00000131308
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr7_-_17412559 0.00 ENSDART00000163020
nitr3a
novel immune-type receptor 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.2 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 4.3 GO:0046777 protein autophosphorylation(GO:0046777)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis