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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox4a+sox4b

Z-value: 0.57

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Transcription factors associated with sox4a+sox4b

Gene Symbol Gene ID Gene Info
ENSDARG00000004588 SRY-box transcription factor 4a
ENSDARG00000098834 SRY-box transcription factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox4bdr11_v1_chr16_+_68069_68124-0.727.1e-04Click!
sox4adr11_v1_chr19_-_28789404_28789409-0.465.5e-02Click!

Activity profile of sox4a+sox4b motif

Sorted Z-values of sox4a+sox4b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_18152407 0.91 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr24_-_37568359 0.68 ENSDART00000056286
H1 histone family, member 0
chr22_+_8979955 0.62 ENSDART00000144005
si:ch211-213a13.1
chr13_+_22675802 0.59 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr8_-_49908978 0.58 ENSDART00000172642
ATP/GTP binding protein 1
chr1_+_44173245 0.52 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr16_-_6944927 0.47 ENSDART00000149620
phosphomevalonate kinase
chr12_-_33646010 0.47 ENSDART00000111259
transmembrane protein 94
chr20_+_34770197 0.46 ENSDART00000018304
minichromosome maintenance complex component 3
chr13_+_39188737 0.46 ENSDART00000083641
family with sequence similarity 135, member A
chr19_-_46037835 0.46 ENSDART00000163815
nucleoporin 153
chr5_+_44846434 0.46 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr11_+_807153 0.45 ENSDART00000173289
vestigial-like family member 4b
chr15_+_22435460 0.44 ENSDART00000031976
transmembrane protein 136a
chr7_+_16348835 0.44 ENSDART00000002449
metallophosphoesterase domain containing 2a
chr19_+_7424347 0.43 ENSDART00000004622
splicing factor 3b, subunit 4
chr6_-_54126463 0.43 ENSDART00000161059
tumor suppressor candidate 2a
chr10_-_35103208 0.42 ENSDART00000192734
zgc:110006
chr15_+_12429206 0.40 ENSDART00000168997
transmembrane protease, serine 4a
chr24_-_35707552 0.40 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr14_+_6963312 0.40 ENSDART00000150050
heterogeneous nuclear ribonucleoprotein A/Ba
chr6_+_12968101 0.39 ENSDART00000013781
minichromosome maintenance complex component 6
chr14_+_6962271 0.39 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr7_-_24995631 0.38 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr16_+_6944564 0.37 ENSDART00000104252
ELL associated factor 1
chr23_-_10745288 0.37 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr2_-_24069331 0.37 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
solute carrier family 12 (potassium/chloride transporter), member 7a
chr6_-_8244474 0.36 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr16_-_33105677 0.36 ENSDART00000145055
proline-rich nuclear receptor coactivator 2
chr11_+_11152214 0.36 ENSDART00000148030
lymphocyte antigen 75
chr9_+_12948511 0.35 ENSDART00000135797
si:dkey-230p4.1
chr12_-_5188413 0.34 ENSDART00000161988
FRA10A associated CGG repeat 1
chr5_+_44846280 0.34 ENSDART00000084370
KN motif and ankyrin repeat domains 1a
chr2_+_2967255 0.34 ENSDART00000167649
ENSDART00000166449
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr17_-_2036850 0.33 ENSDART00000186048
ENSDART00000188838
ENSDART00000186423
serine peptidase inhibitor, Kunitz type 1 a
chr8_+_17869225 0.33 ENSDART00000080079
solute carrier family 44, member 5b
chr3_-_13955878 0.33 ENSDART00000166804
glutaryl-CoA dehydrogenase b
chr3_-_25054002 0.32 ENSDART00000086768
E1A binding protein p300 b
chr25_-_12902242 0.31 ENSDART00000164733
septin 15
chr12_+_17436904 0.31 ENSDART00000079130
ATPase family, AAA domain containing 1b
chr8_+_29636431 0.31 ENSDART00000133047
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr6_+_7322587 0.31 ENSDART00000065500
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr19_+_7636941 0.30 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr14_-_44773864 0.30 ENSDART00000158386
si:dkey-109l4.3
chr14_+_33525196 0.30 ENSDART00000085335
zinc finger, DHHC-type containing 9
chr11_-_2250767 0.30 ENSDART00000018131
heterogeneous nuclear ribonucleoprotein A1a
chr13_-_21650404 0.30 ENSDART00000078352
tetraspanin 14
chr9_-_36924388 0.30 ENSDART00000059756
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr2_-_23538794 0.29 ENSDART00000143857
si:dkey-58b18.10
chr16_+_6944311 0.28 ENSDART00000144763
ELL associated factor 1
chr22_-_8006342 0.28 ENSDART00000162028
sc:d217
chr2_-_24898226 0.28 ENSDART00000134936
si:dkey-149i17.9
chr2_-_23600821 0.28 ENSDART00000146217

chr20_+_6533260 0.28 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
chr24_-_31194847 0.28 ENSDART00000158808
calponin 3, acidic a
chr16_-_20932896 0.27 ENSDART00000180646
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr4_+_9177997 0.27 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr12_+_19320657 0.27 ENSDART00000100075
ENSDART00000066389
transmembrane protein 184ba
chr18_+_8231138 0.27 ENSDART00000140193
arylsulfatase A
chr18_+_39327010 0.27 ENSDART00000012164
tropomodulin 2
chr16_-_54919260 0.26 ENSDART00000156533
keratinocyte differentiation factor 1a
chr17_+_50074372 0.26 ENSDART00000113644
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr10_-_1697037 0.26 ENSDART00000125188
ENSDART00000002985
serine/arginine-rich splicing factor 9
chr8_+_4803906 0.25 ENSDART00000045533
transmembrane protein 127
chr22_-_22301672 0.25 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr23_+_35714574 0.25 ENSDART00000164616
tubulin, alpha 1c
chr21_+_17110598 0.25 ENSDART00000101282
ENSDART00000191864
breakpoint cluster region
chr2_+_47754419 0.25 ENSDART00000188221
muscleblind-like splicing regulator 1
chr24_-_12983829 0.25 ENSDART00000133324
ddb1 and cul4 associated factor 11
chr13_-_27660955 0.25 ENSDART00000188651
ENSDART00000134494
regulating synaptic membrane exocytosis 1a
chr17_+_7534365 0.24 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr25_-_27665978 0.24 ENSDART00000123590
si:ch211-91p5.3
chr1_-_44701313 0.24 ENSDART00000193926
si:dkey-28b4.8
chr12_+_13348918 0.24 ENSDART00000181373
ribonuclease type III, nuclear
chr17_-_45378473 0.24 ENSDART00000132969
zinc finger protein 106a
chr9_+_48007081 0.23 ENSDART00000060593
ENSDART00000099835
zgc:92380
chr12_-_20616160 0.23 ENSDART00000105362
sorting nexin 11
chr5_-_28149767 0.23 ENSDART00000051515
zgc:110329
chr25_+_12494079 0.23 ENSDART00000163508
microtubule-associated protein 1 light chain 3 beta
chr25_+_26895394 0.23 ENSDART00000155820
si:dkey-42p14.3
chr6_+_7249531 0.23 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
DAZ interacting zinc finger protein 1
chr1_+_44173506 0.22 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr23_-_36306337 0.22 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr2_+_18988407 0.22 ENSDART00000170216
glutamate-ammonia ligase (glutamine synthase) a
chr10_-_2788668 0.22 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr13_+_48358467 0.21 ENSDART00000171080
ENSDART00000162531
mutS homolog 6 (E. coli)
chr7_-_24149670 0.21 ENSDART00000005884
matrix metallopeptidase 14a (membrane-inserted)
chr7_-_26308098 0.21 ENSDART00000146440
ENSDART00000146935
ENSDART00000164627
zgc:77439
chr21_-_9914745 0.21 ENSDART00000172124
Rho GTPase activating protein 24
chr11_-_38492564 0.20 ENSDART00000102850
ELK4, ETS-domain protein
chr6_-_9282080 0.20 ENSDART00000159506
coiled-coil domain containing 14
chr24_+_17142881 0.20 ENSDART00000177272
ENSDART00000192259
ENSDART00000191029
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr16_+_6750756 0.20 ENSDART00000149720
zinc finger protein 236
chr7_-_32629458 0.20 ENSDART00000001376
ADP-ribosylation factor-like 14 effector protein
chr4_-_20135406 0.20 ENSDART00000161343
centrosomal protein 83
chr10_-_25628555 0.20 ENSDART00000143978
T cell lymphoma invasion and metastasis 1a
chr8_-_20862443 0.19 ENSDART00000147267
si:ch211-133l5.8
chr3_-_36364903 0.19 ENSDART00000028883
guanine nucleotide binding protein (G protein), alpha 13b
chr17_+_25849332 0.19 ENSDART00000191994
acyl-CoA synthetase short chain family member 1
chr9_+_54179306 0.19 ENSDART00000189829
thymosin, beta 4 x
chr16_-_24612871 0.19 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
FXYD domain containing ion transport regulator 6 like
chr17_+_7534180 0.19 ENSDART00000187512
SNF2 histone linker PHD RING helicase
chr4_+_9178913 0.18 ENSDART00000168558
nuclear transcription factor Y, beta a
chr16_+_29586468 0.18 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr2_-_7696287 0.18 ENSDART00000190769

chr24_+_24923166 0.18 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr16_+_19013257 0.18 ENSDART00000144102
si:ch211-254p10.2
chr3_-_16110100 0.18 ENSDART00000051807
LIM and SH3 protein 1
chr14_+_39258569 0.18 ENSDART00000103298
diaphanous-related formin 2
chr22_-_22337382 0.18 ENSDART00000144684
si:ch211-129c21.1
chr22_-_33916620 0.18 ENSDART00000191276

chr11_-_38492269 0.17 ENSDART00000065613
ELK4, ETS-domain protein
chr14_-_28430505 0.17 ENSDART00000192373
NIMA-related kinase 12
chr9_-_54840124 0.17 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr14_-_5642371 0.17 ENSDART00000183859
ENSDART00000054876
nucleophosmin 1b
chr19_-_17774875 0.17 ENSDART00000151133
ENSDART00000130695
DNA topoisomerase II beta
chr15_+_34963316 0.17 ENSDART00000153840
si:ch73-95l15.5
chr19_-_7540821 0.17 ENSDART00000143958
limb and CNS expressed 1 like
chr4_-_20511595 0.16 ENSDART00000185806
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr3_-_16110351 0.16 ENSDART00000064838
LIM and SH3 protein 1
chr19_-_30800004 0.16 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
tRNA isopentenyltransferase 1
chr1_+_17376922 0.16 ENSDART00000145068
FAT atypical cadherin 1a
chr25_+_3507368 0.16 ENSDART00000157777
zgc:153293
chr25_+_25737386 0.16 ENSDART00000108476
leucine rich repeat containing 61
chr23_+_12361899 0.16 ENSDART00000143728
phosphatidylinositol glycan anchor biosynthesis, class T
chr17_-_43012390 0.16 ENSDART00000155615
autophagy related 2B
chr15_-_15469079 0.15 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr7_-_24875421 0.15 ENSDART00000173920
adenosine deaminase domain containing 2
chr22_-_7025393 0.15 ENSDART00000003422
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr5_+_1965296 0.15 ENSDART00000156224
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr24_+_9696760 0.15 ENSDART00000140200
ENSDART00000187411
DNA topoisomerase II binding protein 1
chr9_+_33334501 0.15 ENSDART00000006867
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr12_-_22400999 0.15 ENSDART00000153194
si:dkey-38p12.3
chr5_+_15203421 0.15 ENSDART00000040826
T-box 1
chr14_-_31151148 0.14 ENSDART00000026569
glypican 4
chr7_+_10563017 0.14 ENSDART00000193520
ENSDART00000173125
zinc finger, AN1-type domain 6
chr23_+_36306539 0.14 ENSDART00000053267
heterogeneous nuclear ribonucleoprotein A1b
chr10_-_25591194 0.13 ENSDART00000131640
T cell lymphoma invasion and metastasis 1a
chr21_-_40782393 0.13 ENSDART00000075808
amyloid beta (A4) precursor protein-binding, family B, member 3
chr17_+_23556764 0.13 ENSDART00000146787
pantothenate kinase 1a
chr10_-_36633882 0.13 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr19_-_29853402 0.13 ENSDART00000024292
ENSDART00000188508
taxilin alpha
chr1_+_29766725 0.13 ENSDART00000054064
zinc finger CCCH-type containing 13
chr7_-_69636502 0.13 ENSDART00000126739
tetraspanin 5a
chr12_+_20122711 0.13 ENSDART00000184411
mahogunin, ring finger 1a
chr5_-_30615901 0.13 ENSDART00000147769
si:ch211-117m20.5
chr17_+_24632440 0.13 ENSDART00000157092
mitogen-activated protein kinase kinase kinase kinase 3b
chr4_+_13953537 0.13 ENSDART00000133596
periphilin 1
chr3_+_52999962 0.12 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr7_-_38340674 0.12 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr2_+_45068366 0.12 ENSDART00000142175
si:dkey-76d14.2
chr12_-_20120702 0.12 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
UBA-like domain containing 1a
chr6_-_45949121 0.12 ENSDART00000058555
TAR DNA binding protein
chr8_+_23093155 0.12 ENSDART00000063075
zgc:100920
chr24_-_33756003 0.12 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr13_+_28732101 0.12 ENSDART00000015773
LIM domain binding 1a
chr8_-_19467011 0.12 ENSDART00000162010
zgc:92140
chr23_-_44226556 0.12 ENSDART00000149115
zgc:158659
chr24_+_7495945 0.12 ENSDART00000133525
ENSDART00000182460
ENSDART00000162954
lysine (K)-specific methyltransferase 2Ca
chr23_-_17866100 0.11 ENSDART00000079506
tuftelin interacting protein 11
chr6_-_40768654 0.11 ENSDART00000184668
ENSDART00000146470
actin related protein 2/3 complex, subunit 4
chr22_+_18886209 0.11 ENSDART00000144402
follistatin-like 3 (secreted glycoprotein)
chr23_+_36083529 0.11 ENSDART00000053295
ENSDART00000130260
homeobox C10a
chr22_+_38276024 0.11 ENSDART00000143792
REST corepressor 3
chr5_-_5669879 0.11 ENSDART00000191963

chr12_+_9817440 0.11 ENSDART00000137081
ENSDART00000123712
RUN domain containing 3Ab
chr15_+_28368644 0.11 ENSDART00000168453
solute carrier family 43 (amino acid system L transporter), member 2a
chr4_-_15003854 0.11 ENSDART00000134701
ENSDART00000002401
kelch domain containing 10
chr15_+_28368823 0.11 ENSDART00000142298
solute carrier family 43 (amino acid system L transporter), member 2a
chr22_+_4443689 0.11 ENSDART00000185490
toll-like receptor adaptor molecule 1
chr14_-_12106603 0.10 ENSDART00000054619
phosphoribosyl pyrophosphate synthetase 1B
chr13_-_33317323 0.10 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
transmembrane protein 234
chr17_+_19626479 0.10 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr17_+_20504196 0.10 ENSDART00000190539
neuralized E3 ubiquitin protein ligase 1Ab
chr23_-_3759345 0.10 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
high mobility group AT-hook 1a
chr6_+_11249706 0.09 ENSDART00000186547
ENSDART00000193287
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr8_-_44611357 0.09 ENSDART00000063396
BCL2 associated athanogene 4
chr5_+_23045096 0.09 ENSDART00000171719
alpha thalassemia/mental retardation syndrome X-linked, like
chr15_-_15468326 0.09 ENSDART00000161192
RAB34, member RAS oncogene family a
chr3_+_34985895 0.09 ENSDART00000121981
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr7_-_31618166 0.09 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr7_-_12909352 0.09 ENSDART00000172901
SH3-domain GRB2-like 3a
chr11_+_35364445 0.09 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr25_-_3503164 0.09 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
si:ch211-272n13.7
chr3_-_21348478 0.08 ENSDART00000114906
family with sequence similarity 171, member A2a
chr19_-_19339285 0.08 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr5_+_41477954 0.08 ENSDART00000185871
protein inhibitor of activated STAT, 2
chr22_+_14117078 0.07 ENSDART00000013575
basic leucine zipper and W2 domains 1a
chr23_-_31974060 0.07 ENSDART00000168087

chr6_+_18367388 0.07 ENSDART00000163394
diacylglycerol kinase, epsilon
chr13_+_5978809 0.07 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr17_-_24680965 0.07 ENSDART00000154880
Rho guanine nucleotide exchange factor (GEF) 33
chr18_+_30998472 0.07 ENSDART00000154993
ENSDART00000099333
CD151 antigen, like
chr23_+_41800052 0.07 ENSDART00000141484
prodynorphin
chr23_+_9088191 0.07 ENSDART00000030811
Cdk5 and Abl enzyme substrate 2b
chr20_-_26846028 0.07 ENSDART00000136687
myosin light chain kinase family, member 4b
chr14_-_2933185 0.07 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr5_+_19448078 0.07 ENSDART00000088968
ubiquitin protein ligase E3B
chr15_-_22147860 0.07 ENSDART00000149784
sodium channel, voltage-gated, type III, beta
chr14_-_8080416 0.07 ENSDART00000045109
zgc:92242

Network of associatons between targets according to the STRING database.

First level regulatory network of sox4a+sox4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.9 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0003156 regulation of organ formation(GO:0003156)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.4 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0032816 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081) myeloid leukocyte cytokine production(GO:0061082)
0.0 0.2 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.7 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.9 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.4 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.2 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants