Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for sox19a+sox2

Z-value: 2.32

Motif logo

Transcription factors associated with sox19a+sox2

Gene Symbol Gene ID Gene Info
ENSDARG00000010770 SRY-box transcription factor 19a
ENSDARG00000070913 SRY-box transcription factor 2
ENSDARG00000110497 SRY-box transcription factor 19a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox2dr11_v1_chr22_-_37349967_37349967-0.653.3e-03Click!
sox19adr11_v1_chr5_-_24201437_24201437-0.391.1e-01Click!

Activity profile of sox19a+sox2 motif

Sorted Z-values of sox19a+sox2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_2393764 8.45 ENSDART00000172624
chimerin 1
chr5_+_44846434 8.17 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr12_+_48340133 6.85 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr13_-_17860307 5.60 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr14_-_5642371 5.11 ENSDART00000183859
ENSDART00000054876
nucleophosmin 1b
chr20_-_29498178 4.91 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr1_+_44173506 4.91 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr5_-_28149767 4.76 ENSDART00000051515
zgc:110329
chr1_+_44173245 4.58 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr12_-_33357655 4.52 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr5_+_44846280 4.51 ENSDART00000084370
KN motif and ankyrin repeat domains 1a
chr23_+_30736895 4.33 ENSDART00000042944
additional sex combs like transcriptional regulator 1
chr2_+_38025260 4.30 ENSDART00000075905
heterogeneous nuclear ribonucleoprotein C
chr7_+_58751504 4.11 ENSDART00000024185
zgc:56231
chr11_-_25257595 4.05 ENSDART00000123567
snail family zinc finger 1a
chr10_+_3153973 4.03 ENSDART00000183223
hypermethylated in cancer 2
chr8_+_52442622 4.02 ENSDART00000012758
zgc:77112
chr10_+_2842923 4.00 ENSDART00000181895
YKT6 v-SNARE homolog (S. cerevisiae)
chr2_-_49031303 3.99 ENSDART00000143471
cell division cycle 34 homolog (S. cerevisiae) b
chr18_+_8912113 3.93 ENSDART00000147467
transmembrane protein 243, mitochondrial a
chr4_-_837768 3.89 ENSDART00000185280
ENSDART00000135618
sine oculis binding protein homolog (Drosophila) b
chr9_+_8396755 3.89 ENSDART00000043067
zgc:171776
chr20_+_26939742 3.85 ENSDART00000138369
ENSDART00000062061
ENSDART00000152992
cell division cycle associated 4
chr5_+_57924611 3.78 ENSDART00000050949
B-cell translocation gene 4
chr12_-_33354409 3.76 ENSDART00000178515
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_-_26832685 3.75 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr21_-_30082414 3.71 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr13_+_30506781 3.67 ENSDART00000110884
zinc finger, MIZ-type containing 1a
chr2_-_32688905 3.67 ENSDART00000041146
nuclear receptor binding protein 2a
chr16_+_35535171 3.63 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr15_+_11644866 3.59 ENSDART00000188716
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_+_19245804 3.57 ENSDART00000134514
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr15_-_16076399 3.56 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
serine/arginine-rich splicing factor 1a
chr19_-_47570672 3.47 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr19_-_47832853 3.43 ENSDART00000170988
argonaute RISC catalytic component 4
chr20_+_26940178 3.31 ENSDART00000190888
cell division cycle associated 4
chr18_-_25051846 3.30 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr11_-_25257045 3.25 ENSDART00000130477
snail family zinc finger 1a
chr8_+_23356264 3.22 ENSDART00000145062
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr5_-_15494164 3.16 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr18_+_8912710 3.12 ENSDART00000142866
transmembrane protein 243, mitochondrial a
chr21_-_18275226 3.12 ENSDART00000126672
ENSDART00000135239
bromodomain containing 3a
chr22_-_10541372 3.11 ENSDART00000179708
si:dkey-42i9.4
chr6_-_49547680 3.10 ENSDART00000169678
protein phosphatase 4, regulatory subunit 1-like
chr1_+_22654875 3.10 ENSDART00000019698
ENSDART00000161874
annexin A5b
chr19_-_18135724 3.08 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr25_+_33063762 3.06 ENSDART00000189974
talin 2b
chr16_+_35535375 3.05 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr14_+_6963312 3.05 ENSDART00000150050
heterogeneous nuclear ribonucleoprotein A/Ba
chr18_+_8912536 3.03 ENSDART00000134827
ENSDART00000061904
transmembrane protein 243, mitochondrial a
chr5_-_33230794 3.00 ENSDART00000144273
KN motif and ankyrin repeat domains 1b
chr20_-_3238110 2.99 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr15_-_31265375 2.99 ENSDART00000086592
vascular endothelial zinc finger 1b
chr8_+_14987006 2.97 ENSDART00000045038
formin binding protein 1-like
chr23_-_36449111 2.96 ENSDART00000110478
zgc:174906
chr6_+_23809501 2.93 ENSDART00000168701
glutamate-ammonia ligase (glutamine synthase) b
chr8_+_14986833 2.93 ENSDART00000171867
ENSDART00000191374
formin binding protein 1-like
chr3_+_43102010 2.92 ENSDART00000162096
mical-like 2a
chr5_-_72390259 2.91 ENSDART00000172302
WW domain binding protein 1
chr11_+_13424116 2.91 ENSDART00000125563
homer scaffolding protein 3b
chr19_-_47571456 2.90 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr1_+_49878000 2.89 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr20_-_3319642 2.88 ENSDART00000186743
ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr7_-_26601307 2.87 ENSDART00000188934
phospholipid scramblase 3b
chr17_-_45125537 2.87 ENSDART00000113552
zgc:163014
chr23_-_10745288 2.87 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr22_+_15960005 2.87 ENSDART00000033617
scl/tal1 interrupting locus
chr25_+_8921425 2.86 ENSDART00000128591
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr19_-_46037835 2.85 ENSDART00000163815
nucleoporin 153
chr2_+_15048410 2.83 ENSDART00000058484
calponin 3, acidic b
chr17_+_1360192 2.83 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr22_+_15959844 2.82 ENSDART00000182201
scl/tal1 interrupting locus
chr4_-_20108833 2.82 ENSDART00000100867
family with sequence similarity 3, member C
chr15_-_28587147 2.81 ENSDART00000156049
slingshot protein phosphatase 2a
chr23_-_31645760 2.80 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr21_+_3166988 2.78 ENSDART00000168163
heterogeneous nuclear ribonucleoprotein A/Bb
chr23_-_3758637 2.76 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr7_+_40081630 2.75 ENSDART00000173559
zgc:112356
chr20_+_51730658 2.75 ENSDART00000010271
axin interactor, dorsalization associated
chr2_-_37477654 2.74 ENSDART00000193921
death-associated protein kinase 3
chr21_+_34119759 2.74 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr12_+_23991639 2.74 ENSDART00000003143
proteasome activator subunit 4b
chr17_-_4252221 2.73 ENSDART00000152020
growth differentiation factor 3
chr5_-_22602979 2.73 ENSDART00000146287
non-POU domain containing, octamer-binding
chr3_+_7771420 2.72 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr18_+_45573416 2.71 ENSDART00000132184
ENSDART00000145288
kinesin family member C3
chr12_-_4475890 2.71 ENSDART00000092492
si:ch211-173d10.1
chr19_-_23249822 2.71 ENSDART00000140665
growth factor receptor-bound protein 10a
chr5_+_33301005 2.71 ENSDART00000006021
ubiquitin specific peptidase 20
chr22_+_15960514 2.70 ENSDART00000181617
scl/tal1 interrupting locus
chr18_+_39487486 2.70 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr7_+_38380135 2.69 ENSDART00000174005
rhophilin, Rho GTPase binding protein 2
chr14_-_7306983 2.68 ENSDART00000158914
si:ch211-51f19.1
chr22_+_2751887 2.67 ENSDART00000133652
si:dkey-20i20.11
chr12_-_10508952 2.66 ENSDART00000152806
zgc:152977
chr12_+_23991276 2.65 ENSDART00000153136
proteasome activator subunit 4b
chr2_-_51087077 2.64 ENSDART00000167987
finTRIM family, member 67
chr8_-_30742233 2.64 ENSDART00000098986
guanylyl cyclase domain containing 1
chr18_-_7032227 2.64 ENSDART00000127138
calumenin b
chr6_+_23809163 2.63 ENSDART00000170402
glutamate-ammonia ligase (glutamine synthase) b
chr19_+_14352332 2.63 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr2_-_21170517 2.63 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr10_+_15255012 2.62 ENSDART00000023766
very low density lipoprotein receptor
chr12_-_27212596 2.62 ENSDART00000153101
proteasome activator subunit 3
chr14_+_12391871 2.62 ENSDART00000115408
ENSDART00000106626
ENSDART00000054611
ENSDART00000126655
THO complex 2
chr6_-_24066659 2.62 ENSDART00000164159
ENSDART00000172051
down-regulator of transcription 1
chr7_-_53117131 2.61 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr9_-_28937880 2.60 ENSDART00000132878
erythrocyte membrane protein band 4.1 like 5
chr8_+_45338073 2.58 ENSDART00000185024
poly(A) binding protein, cytoplasmic 1-like
chr10_-_36633882 2.58 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr10_-_32663759 2.58 ENSDART00000126727
autophagy related 101
chr10_-_28380919 2.58 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
B-cell translocation gene 3
chr8_+_52442785 2.58 ENSDART00000189958
zgc:77112
chr2_-_34138400 2.58 ENSDART00000056667
centromere protein L
chr1_-_31083535 2.57 ENSDART00000138113
protein phosphatase 1 regulatory subunit 9A-like B
chr10_+_15255198 2.56 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr3_-_32873641 2.54 ENSDART00000075277
zgc:113090
chr8_+_12951155 2.53 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr22_-_37565348 2.53 ENSDART00000149482
ENSDART00000104478
fragile X mental retardation, autosomal homolog 1
chr2_-_26596794 2.53 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr10_+_17371356 2.52 ENSDART00000122663
signal peptide peptidase 3
chr16_-_42175617 2.52 ENSDART00000084715
alkB homolog 8, tRNA methyltransferase
chr13_-_35908275 2.51 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr2_+_26240339 2.51 ENSDART00000191006
paralemmin 1b
chr24_-_24724233 2.51 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr23_+_9522942 2.50 ENSDART00000137751
oxysterol binding protein-like 2b
chr9_-_54840124 2.48 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr11_-_44194132 2.48 ENSDART00000182954
ENSDART00000111271

chr19_+_7636941 2.47 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr2_-_44777592 2.47 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr5_-_22602780 2.47 ENSDART00000011699
non-POU domain containing, octamer-binding
chr18_-_12957451 2.47 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr8_+_30742898 2.47 ENSDART00000018475
small nuclear ribonucleoprotein D3 polypeptide
chr5_+_40835601 2.46 ENSDART00000147767
si:dkey-3h3.3
chr18_+_22174630 2.45 ENSDART00000089549
RHO family interacting cell polarization regulator 1
chr17_+_15535501 2.45 ENSDART00000002932
myristoylated alanine-rich protein kinase C substrate b
chr12_-_17592215 2.45 ENSDART00000134597
ubiquitin specific peptidase 42
chr14_-_24277805 2.44 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr8_-_19467011 2.43 ENSDART00000162010
zgc:92140
chr22_-_5171362 2.43 ENSDART00000124889
tumor necrosis factor, alpha-induced protein 8-like 1
chr5_+_26212621 2.42 ENSDART00000134432
occludin b
chr2_+_32846602 2.41 ENSDART00000056649
transmembrane protein 53
chr14_+_15155684 2.41 ENSDART00000167966
zgc:158852
chr9_+_21793565 2.40 ENSDART00000134915
REV1, polymerase (DNA directed)
chr3_-_26191960 2.40 ENSDART00000113843
yippee-like 3
chr12_-_27212880 2.39 ENSDART00000002835
proteasome activator subunit 3
chr21_-_43665537 2.39 ENSDART00000157610
si:dkey-229d11.3
chr5_-_3960161 2.38 ENSDART00000111453
myosin XIX
chr20_+_26943072 2.37 ENSDART00000153215
cell division cycle associated 4
chr9_+_33340311 2.37 ENSDART00000140064
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr2_-_10386738 2.37 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr6_-_26080384 2.36 ENSDART00000157181
ENSDART00000154568
heparan sulfate 2-O-sulfotransferase 1b
chr20_+_27749133 2.35 ENSDART00000089013
vertebrae development associated
chr9_-_41090048 2.35 ENSDART00000131681
ENSDART00000182552
asparagine synthetase domain containing 1
chr8_-_1838315 2.35 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr10_-_21362320 2.34 ENSDART00000189789
avidin
chr21_+_15790366 2.34 ENSDART00000101956
protein tyrosine phosphatase, receptor type, A
chr22_+_336256 2.34 ENSDART00000019155
B-cell translocation gene 2
chr25_-_12902242 2.33 ENSDART00000164733
septin 15
chr16_+_25259313 2.33 ENSDART00000058938
F-box protein 32
chr10_-_35257458 2.33 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr22_-_10541712 2.33 ENSDART00000013933
si:dkey-42i9.4
chr5_+_29831235 2.32 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr23_+_36308428 2.32 ENSDART00000134607
heterogeneous nuclear ribonucleoprotein A1b
chr23_-_27822920 2.32 ENSDART00000023094
activin A receptor type 1Ba
chr7_-_24875421 2.31 ENSDART00000173920
adenosine deaminase domain containing 2
chr5_+_3891485 2.30 ENSDART00000129329
ENSDART00000091711
RPA interacting protein
chr5_-_56964547 2.28 ENSDART00000074400
TIA1 cytotoxic granule-associated RNA binding protein
chr2_+_26240631 2.28 ENSDART00000129895
paralemmin 1b
chr21_+_12056934 2.27 ENSDART00000125380
zgc:162344
chr8_+_47677208 2.27 ENSDART00000123254
dipeptidyl-peptidase 9
chr13_-_45022527 2.25 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr12_+_30788912 2.25 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr5_+_34549845 2.24 ENSDART00000139317
allograft inflammatory factor 1-like
chr13_+_51710725 2.24 ENSDART00000163741
PWWP domain containing 2B
chr19_+_46113828 2.23 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr13_+_22675802 2.23 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr15_+_24756860 2.22 ENSDART00000156424
ENSDART00000078035
carboxypeptidase D, a
chr3_+_29082267 2.22 ENSDART00000145615
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr8_-_9570511 2.20 ENSDART00000044000
plexin A3
chr2_-_21167652 2.19 ENSDART00000185792
bmi1 polycomb ring finger oncogene 1b
chr7_+_36467796 2.19 ENSDART00000146202
akt interacting protein
chr23_+_36308717 2.19 ENSDART00000131711
heterogeneous nuclear ribonucleoprotein A1b
chr6_-_46735380 2.18 ENSDART00000103455
TAR (HIV) RNA binding protein 2
chr16_+_26846495 2.18 ENSDART00000078124
tripartite motif containing 35-29
chr5_-_39805620 2.18 ENSDART00000137801
RasGEF domain family, member 1Ba
chr17_+_28005763 2.18 ENSDART00000155838
leucine zipper protein 1
chr15_+_29025090 2.17 ENSDART00000131755
si:ch211-137a8.2
chr14_-_32876280 2.15 ENSDART00000173168
si:rp71-46j2.7
chr22_-_718615 2.15 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr17_-_24866727 2.15 ENSDART00000027957
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr16_-_31342356 2.14 ENSDART00000136648
maestro heat-like repeat family member 1
chr14_+_35464994 2.14 ENSDART00000115307
si:ch211-203d1.3
chr11_-_11792766 2.13 ENSDART00000011657
cell division cycle 6 homolog (S. cerevisiae)
chr5_+_36666715 2.13 ENSDART00000097686
zgc:153990
chr11_-_24063196 2.13 ENSDART00000036513
tribbles pseudokinase 3
chr3_+_32791786 2.12 ENSDART00000180174
TBC1 domain family, member 10b
chr2_-_23390779 2.12 ENSDART00000020136
influenza virus NS1A binding protein b
chr2_-_32262287 2.12 ENSDART00000056621
ENSDART00000039717
family with sequence similarity 49, member Ba
chr10_+_11261576 2.11 ENSDART00000155333
hydroxysteroid dehydrogenase like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19a+sox2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0021557 oculomotor nerve development(GO:0021557)
1.4 5.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.2 13.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.0 15.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 3.8 GO:0070987 error-free translesion synthesis(GO:0070987)
1.0 3.8 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.9 8.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.9 5.5 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.9 5.4 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.9 18.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.9 2.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.9 2.6 GO:0005997 xylulose metabolic process(GO:0005997)
0.8 2.5 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.8 5.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.8 2.4 GO:0061355 Wnt protein secretion(GO:0061355)
0.7 2.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.7 2.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.7 2.8 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.7 2.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.7 2.6 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.6 4.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.6 2.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.6 2.9 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.6 5.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 1.7 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.6 1.1 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.5 1.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.5 2.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.5 2.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.5 2.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.5 3.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.5 1.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.5 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 2.0 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.5 4.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.5 1.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.5 1.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.5 1.4 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.5 1.4 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.5 2.3 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.4 1.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.4 1.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.4 1.3 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 1.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.3 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.4 1.3 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.4 2.1 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.4 1.2 GO:0030237 female sex determination(GO:0030237)
0.4 3.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.4 1.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.4 1.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4 4.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.4 3.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 0.8 GO:0032196 transposition(GO:0032196)
0.4 0.8 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.4 1.5 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.1 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.4 4.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.4 1.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 0.7 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.4 1.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.4 8.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.4 3.5 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.3 1.0 GO:0034476 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.3 2.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 3.1 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 1.7 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.3 1.7 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 5.6 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.3 3.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 3.0 GO:0006465 signal peptide processing(GO:0006465)
0.3 1.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.3 1.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 1.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 1.2 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 2.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 1.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 1.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 6.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.3 1.8 GO:1902946 protein localization to early endosome(GO:1902946)
0.3 1.5 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.3 4.7 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 1.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 1.4 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.3 0.8 GO:2000434 regulation of protein neddylation(GO:2000434)
0.3 2.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.3 0.8 GO:0071514 genetic imprinting(GO:0071514)
0.3 1.9 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.3 1.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.6 GO:0010269 response to selenium ion(GO:0010269)
0.3 2.9 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.3 10.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.3 1.8 GO:0030728 ovulation(GO:0030728)
0.3 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.3 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.3 0.8 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.3 1.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.3 1.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.3 1.3 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 1.3 GO:0080009 mRNA methylation(GO:0080009)
0.2 2.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 1.2 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.2 1.2 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 1.2 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 11.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 1.9 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 21.1 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.2 1.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.1 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.2 2.2 GO:0001709 cell fate determination(GO:0001709)
0.2 0.7 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 1.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 20.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 1.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 2.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 3.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 5.8 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.2 0.2 GO:0072539 CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) T-helper cell differentiation(GO:0042093) CD4-positive, alpha-beta T cell differentiation(GO:0043367) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.2 1.0 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 1.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.8 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 1.4 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.8 GO:0038203 TORC2 signaling(GO:0038203)
0.2 3.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 1.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 2.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 0.9 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.2 0.9 GO:0034505 tooth mineralization(GO:0034505)
0.2 1.5 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.2 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.6 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.2 3.9 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.9 GO:0000012 single strand break repair(GO:0000012)
0.2 1.0 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 1.0 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 5.0 GO:0016925 protein sumoylation(GO:0016925)
0.2 5.5 GO:0030488 tRNA methylation(GO:0030488)
0.2 1.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.0 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 0.7 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.2 1.9 GO:0006032 chitin catabolic process(GO:0006032)
0.2 3.3 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 1.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.2 0.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.8 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.2 2.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 1.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.2 2.4 GO:0090559 regulation of membrane permeability(GO:0090559)
0.2 1.1 GO:0002931 response to ischemia(GO:0002931)
0.2 2.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2 1.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2 3.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.2 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 7.8 GO:0006405 RNA export from nucleus(GO:0006405)
0.2 1.1 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.3 GO:0006273 lagging strand elongation(GO:0006273)
0.1 1.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 5.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.4 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 12.5 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 0.7 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.8 GO:0035889 otolith tethering(GO:0035889)
0.1 1.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.3 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.4 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 3.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 5.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 3.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.9 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.7 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.6 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 1.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.4 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 1.3 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.7 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 1.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.2 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 2.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 7.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.6 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.4 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.1 1.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.8 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 4.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 0.6 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 5.1 GO:0016575 histone deacetylation(GO:0016575)
0.1 2.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 2.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 2.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 1.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:0006404 RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030) snRNA import into nucleus(GO:0061015)
0.1 7.4 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 3.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 13.6 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.9 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 10.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.9 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918) cellular response to dsRNA(GO:0071359)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.5 GO:0048532 anatomical structure arrangement(GO:0048532)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.0 GO:0060541 respiratory system development(GO:0060541)
0.1 0.6 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 7.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 1.3 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.7 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:0016246 RNA interference(GO:0016246)
0.1 2.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.6 GO:0034063 cytoplasmic mRNA processing body assembly(GO:0033962) stress granule assembly(GO:0034063)
0.1 1.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.3 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 1.5 GO:0043506 regulation of JUN kinase activity(GO:0043506)
0.1 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.2 GO:0098534 centriole assembly(GO:0098534)
0.1 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 3.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 1.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 1.9 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.5 GO:0001966 thigmotaxis(GO:0001966)
0.1 5.5 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.1 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 1.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.5 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.4 GO:0060021 palate development(GO:0060021)
0.1 0.6 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0048640 negative regulation of developmental growth(GO:0048640)
0.1 4.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.3 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 3.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 0.3 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.1 1.9 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 1.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 2.3 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 0.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 1.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.8 GO:0006301 postreplication repair(GO:0006301)
0.1 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.1 1.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 3.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 2.1 GO:0008643 carbohydrate transport(GO:0008643)
0.1 5.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.9 GO:0001843 neural tube closure(GO:0001843)
0.1 1.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.2 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.3 GO:0048823 nucleate erythrocyte differentiation(GO:0043363) nucleate erythrocyte development(GO:0048823)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.9 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.2 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.9 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.0 GO:0043113 receptor clustering(GO:0043113)
0.0 1.9 GO:0045010 actin nucleation(GO:0045010)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.9 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 1.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.7 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.6 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 2.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 2.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 2.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 2.6 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 4.8 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0001878 response to yeast(GO:0001878)
0.0 1.0 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 0.7 GO:0043588 skin development(GO:0043588)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 3.8 GO:0051604 protein maturation(GO:0051604)
0.0 1.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.2 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.2 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 3.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.5 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.8 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.5 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0042476 odontogenesis(GO:0042476)
0.0 0.3 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.3 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 5.3 GO:0006897 endocytosis(GO:0006897)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal absorption(GO:0070293) renal sodium ion absorption(GO:0070294)
0.0 0.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.6 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.6 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.1 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:1990111 spermatoproteasome complex(GO:1990111)
1.3 5.0 GO:0008537 proteasome activator complex(GO:0008537)
0.9 2.6 GO:0031213 RSF complex(GO:0031213)
0.8 5.9 GO:0035517 PR-DUB complex(GO:0035517)
0.7 2.2 GO:0070578 RISC-loading complex(GO:0070578)
0.7 3.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.7 2.0 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.6 2.5 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.6 2.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.6 6.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 4.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.6 4.7 GO:0035060 brahma complex(GO:0035060)
0.6 2.9 GO:0005845 mRNA cap binding complex(GO:0005845)
0.6 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 2.6 GO:0008091 spectrin(GO:0008091)
0.5 1.5 GO:0042382 paraspeckles(GO:0042382)
0.5 1.4 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5 1.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 1.8 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.4 1.6 GO:0070209 ASTRA complex(GO:0070209)
0.4 6.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 2.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.4 5.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 2.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 2.2 GO:0070695 FHF complex(GO:0070695)
0.4 1.1 GO:1990745 EARP complex(GO:1990745)
0.4 1.4 GO:0044609 DBIRD complex(GO:0044609)
0.4 5.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.4 1.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 1.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.4 1.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 10.9 GO:0090544 BAF-type complex(GO:0090544)
0.3 2.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 6.5 GO:0035102 PRC1 complex(GO:0035102)
0.3 0.8 GO:0089701 U2AF(GO:0089701)
0.3 2.1 GO:0000796 condensin complex(GO:0000796)
0.3 1.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 2.0 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 1.8 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 5.9 GO:0005685 U1 snRNP(GO:0005685)
0.3 4.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 4.6 GO:0030057 desmosome(GO:0030057)
0.2 1.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 2.7 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.4 GO:0016586 RSC complex(GO:0016586)
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 7.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 0.6 GO:0010369 chromocenter(GO:0010369)
0.2 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 2.4 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 3.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 7.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.6 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 4.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 2.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 2.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 4.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 13.6 GO:0016607 nuclear speck(GO:0016607)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.7 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 9.4 GO:0001726 ruffle(GO:0001726)
0.1 0.6 GO:0030914 STAGA complex(GO:0030914)
0.1 1.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 2.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 8.3 GO:0005871 kinesin complex(GO:0005871)
0.1 1.0 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 3.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 10.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 1.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 4.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.4 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.8 GO:0000792 heterochromatin(GO:0000792)
0.1 0.9 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 4.9 GO:0030027 lamellipodium(GO:0030027)
0.1 1.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 5.7 GO:0005795 Golgi stack(GO:0005795)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 3.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.2 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 4.5 GO:0005681 spliceosomal complex(GO:0005681)
0.1 2.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 3.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 5.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 7.2 GO:0005938 cell cortex(GO:0005938)
0.0 4.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 9.9 GO:0005730 nucleolus(GO:0005730)
0.0 1.4 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.1 GO:0000323 lytic vacuole(GO:0000323)
0.0 0.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 6.5 GO:0000785 chromatin(GO:0000785)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 13.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0055029 nuclear DNA-directed RNA polymerase complex(GO:0055029)
0.0 1.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0051059 NF-kappaB binding(GO:0051059)
1.7 6.9 GO:0071889 14-3-3 protein binding(GO:0071889)
1.6 11.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.3 5.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.3 6.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.0 10.4 GO:0016504 peptidase activator activity(GO:0016504)
1.0 3.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.9 2.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.9 4.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.8 2.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.8 3.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.8 5.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.8 2.4 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.7 2.2 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.7 3.7 GO:0035197 siRNA binding(GO:0035197)
0.7 8.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 2.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.6 3.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.6 1.8 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.6 4.5 GO:0030619 U1 snRNA binding(GO:0030619)
0.5 2.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.5 3.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 2.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.5 2.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 1.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.5 2.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 1.9 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 2.3 GO:0009374 biotin binding(GO:0009374)
0.4 2.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 1.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.4 6.6 GO:2001069 glycogen binding(GO:2001069)
0.4 3.5 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.3 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.4 1.3 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 3.4 GO:0035198 miRNA binding(GO:0035198)
0.4 1.7 GO:0070513 death domain binding(GO:0070513)
0.4 3.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.4 1.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.4 5.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 1.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 1.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 1.5 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 1.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.4 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.4 1.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.4 1.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.3 4.2 GO:0005158 insulin receptor binding(GO:0005158)
0.3 1.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 4.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.7 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 2.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.3 1.6 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.3 1.0 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.3 1.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 2.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 0.9 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.3 1.5 GO:0008432 JUN kinase binding(GO:0008432)
0.3 2.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 1.8 GO:0015616 DNA translocase activity(GO:0015616)
0.3 6.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 6.0 GO:0008143 poly(A) binding(GO:0008143)
0.3 1.7 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 2.8 GO:0005522 profilin binding(GO:0005522)
0.3 1.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.3 0.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 3.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 1.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 1.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.0 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 2.0 GO:0016530 metallochaperone activity(GO:0016530)
0.2 0.7 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.2 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 2.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.2 1.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 4.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 1.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 2.7 GO:0043495 protein anchor(GO:0043495)
0.2 4.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 5.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 6.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 1.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 13.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 5.5 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.6 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2 1.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 3.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 1.9 GO:0004568 chitinase activity(GO:0004568)
0.2 1.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.5 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 0.8 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 1.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.2 5.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 2.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 28.4 GO:0042393 histone binding(GO:0042393)
0.1 0.6 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 2.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 3.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 3.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 3.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 8.2 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.4 GO:0070300 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.5 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 1.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 3.6 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 4.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.1 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.1 GO:0051117 ATPase binding(GO:0051117)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.7 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 4.8 GO:0005178 integrin binding(GO:0005178)
0.1 11.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 7.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 7.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 3.8 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 3.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 4.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 21.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.0 GO:0046332 SMAD binding(GO:0046332)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 12.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 15.9 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159) protein complex scaffold(GO:0032947)
0.0 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 2.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0016896 exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 2.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 1.1 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.2 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.1 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 2.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 2.8 GO:0060090 binding, bridging(GO:0060090)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.9 GO:0015211 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleoside transmembrane transporter activity(GO:0015211) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.2 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 13.7 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.4 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 2.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.4 GO:0004518 nuclease activity(GO:0004518)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)
0.0 3.4 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.5 7.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 7.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 5.1 PID REELIN PATHWAY Reelin signaling pathway
0.3 5.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 3.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 12.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 3.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 8.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 1.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.5 PID RHOA PATHWAY RhoA signaling pathway
0.1 3.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.6 PID ATM PATHWAY ATM pathway
0.1 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.1 PID E2F PATHWAY E2F transcription factor network
0.1 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.2 PID INSULIN PATHWAY Insulin Pathway
0.1 2.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.6 PID FOXO PATHWAY FoxO family signaling
0.1 1.7 PID MYC PATHWAY C-MYC pathway
0.1 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 8.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 13.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 10.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 4.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 2.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 3.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 2.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 2.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 1.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 2.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 5.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 3.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 0.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 2.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 2.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 0.7 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.2 3.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.2 2.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 18.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 2.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 1.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 3.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 7.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 4.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.0 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.1 1.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.3 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.9 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 4.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.1 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions