Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for sox18

Z-value: 0.58

Motif logo

Transcription factors associated with sox18

Gene Symbol Gene ID Gene Info
ENSDARG00000058598 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox18dr11_v1_chr23_+_8797143_8797143-0.653.5e-03Click!

Activity profile of sox18 motif

Sorted Z-values of sox18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_44994214 2.14 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr22_+_25352530 1.92 ENSDART00000176742
ENSDART00000113186
si:dkey-240e12.6
chr13_+_25397098 1.55 ENSDART00000132953
glutathione S-transferase omega 2
chr13_+_25396896 1.53 ENSDART00000041257
glutathione S-transferase omega 2
chr1_+_45707219 1.28 ENSDART00000143363
si:ch211-214c7.4
chr5_+_3892551 1.06 ENSDART00000134396
RPA interacting protein
chr22_+_24559947 1.01 ENSDART00000169847
WD repeat domain 47b
chr7_+_24814866 0.96 ENSDART00000173581
si:ch211-226l4.6
chr15_+_29728377 0.92 ENSDART00000099958
zgc:153372
chr24_-_31332087 0.77 ENSDART00000161179
ATP-binding cassette, sub-family D (ALD), member 3a
chr3_+_34159192 0.73 ENSDART00000151119
coactivator-associated arginine methyltransferase 1
chr15_+_29727799 0.68 ENSDART00000182006
zgc:153372
chr24_-_24724233 0.58 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr10_+_4235998 0.57 ENSDART00000169328
phospholipid phosphatase related 1
chr11_+_5565082 0.53 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
chr11_+_17984354 0.52 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr12_+_13348918 0.52 ENSDART00000181373
ribonuclease type III, nuclear
chr23_-_10745288 0.51 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr19_+_9113932 0.51 ENSDART00000060442
SET domain, bifurcated 1a
chr14_+_30272891 0.50 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr2_+_31942390 0.49 ENSDART00000138684
ENSDART00000146758
ENSDART00000137921
OTU deubiquitinase with linear linkage specificity b
chr11_+_17984167 0.49 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr14_-_24277805 0.49 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr22_+_2533514 0.48 ENSDART00000147967
si:ch73-92e7.4
chr17_-_14780578 0.47 ENSDART00000154690
si:ch211-266o15.1
chr5_-_7513082 0.47 ENSDART00000158913
bone morphogenetic protein receptor, type IBa
chr3_+_34986837 0.45 ENSDART00000190341
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr23_+_42482137 0.45 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr1_+_49435017 0.44 ENSDART00000124833
programmed cell death 11
chr17_-_43594864 0.44 ENSDART00000139980
zinc finger, FYVE domain containing 28
chr14_-_35400671 0.44 ENSDART00000129676
LSM11, U7 small nuclear RNA associated
chr17_+_51682429 0.43 ENSDART00000004379
nucleolar protein 10
chr19_-_31035155 0.43 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr7_+_69459759 0.42 ENSDART00000160500
CTD nuclear envelope phosphatase 1b
chr3_+_9588705 0.41 ENSDART00000172543
ENSDART00000104875
TNF receptor-associated protein 1
chr2_+_21185903 0.39 ENSDART00000131369
si:dkey-29d8.3
chr2_+_13722116 0.37 ENSDART00000155015
zinc finger and BTB domain containing 41
chr17_+_16423721 0.37 ENSDART00000064233
EF-hand calcium binding domain 11
chr2_-_32262287 0.35 ENSDART00000056621
ENSDART00000039717
family with sequence similarity 49, member Ba
chr17_+_24597001 0.35 ENSDART00000191834
rearranged L-myc fusion
chr7_+_22853788 0.34 ENSDART00000148502
chloride channel, voltage-sensitive 5b
chr22_+_1786230 0.32 ENSDART00000169318
ENSDART00000164948
zinc finger protein 1154
chr19_+_15440841 0.32 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr23_-_14059085 0.32 ENSDART00000087654
adenylate cyclase 6a
chr18_-_1270220 0.31 ENSDART00000193754
UDP glucuronosyltransferase 5 family, polypeptide F1
chr3_-_23470986 0.30 ENSDART00000113135
male-specific lethal 1 homolog a (Drosophila)
chr4_+_13412030 0.29 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr11_+_43751263 0.29 ENSDART00000163843
zgc:153431
chr18_-_14743659 0.29 ENSDART00000125979
teashirt zinc finger homeobox 3a
chr2_-_9971609 0.29 ENSDART00000137924
ENSDART00000048655
ENSDART00000131613
zgc:55943
chr13_-_42724645 0.28 ENSDART00000046066
calpain 1, (mu/I) large subunit a
chr8_-_25600888 0.27 ENSDART00000193860
serine/threonine kinase 38a
chr20_-_45062514 0.27 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr18_+_39649660 0.27 ENSDART00000149859
gliomedin
chr21_+_43171013 0.27 ENSDART00000151362
zinc finger, CCHC domain containing 10
chr13_-_31164749 0.25 ENSDART00000049180
mitogen-activated protein kinase 8a
chr20_+_18992679 0.25 ENSDART00000147105
ENSDART00000152811
L-threonine dehydrogenase
chr5_-_23517747 0.24 ENSDART00000137655
stromal antigen 2a
chr8_-_17184482 0.24 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr8_+_37700090 0.24 ENSDART00000187885
ENSDART00000127633
adrenoceptor beta 3a
chr21_-_23503032 0.23 ENSDART00000101117
neural cell adhesion molecule 1a
chr18_+_39649825 0.23 ENSDART00000087960
gliomedin
chr3_-_40976463 0.23 ENSDART00000128450
ENSDART00000018676
cytochrome P450, family 3, subfamily c, polypeptide 1
chr25_+_10416583 0.21 ENSDART00000073907
ets homologous factor
chr21_-_30166097 0.20 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr9_+_45680802 0.19 ENSDART00000036369
ankyrin repeat and SOCS box containing 1
chr14_+_6962271 0.19 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr7_+_73827805 0.19 ENSDART00000109316
zgc:173587
chr13_-_45063686 0.16 ENSDART00000130467
ENSDART00000136679
calcineurin-like EF-hand protein 1
chr8_+_23726708 0.16 ENSDART00000142395
makorin, ring finger protein, 4
chr3_+_25999477 0.16 ENSDART00000024316
minichromosome maintenance complex component 5
chr5_+_42912966 0.15 ENSDART00000039973
RUN and FYVE domain containing 3
chr17_-_3303805 0.15 ENSDART00000169136

chr15_+_17722054 0.15 ENSDART00000191390
ENSDART00000169550
si:ch211-213d14.1
chr22_+_1853999 0.14 ENSDART00000163288
zinc finger protein 1174
chr22_+_17118225 0.14 ENSDART00000135604
Fras1 related extracellular matrix 1b
chr2_+_32016516 0.13 ENSDART00000135040
MYC proto-oncogene, bHLH transcription factor b
chr5_-_62317496 0.13 ENSDART00000180089
zgc:85789
chr22_+_29087308 0.12 ENSDART00000186776
ENSDART00000178615
ENSDART00000150811
ENSDART00000150489
phospholipase A2, group VI (cytosolic, calcium-independent)
chr25_+_10987817 0.12 ENSDART00000156529
si:dkey-52p2.5
chr21_+_21012210 0.11 ENSDART00000190317
nodal-related 1
chr13_+_25412307 0.11 ENSDART00000175339
calcium homeostasis modulator 1
chr2_-_27900518 0.11 ENSDART00000109561
ENSDART00000077720
zgc:163121
chr10_+_15511885 0.11 ENSDART00000165663
erbb2 interacting protein
chr17_+_50564070 0.10 ENSDART00000075150
bone morphogenetic protein 4
chr9_+_32306862 0.10 ENSDART00000078513
MOB family member 4, phocein
chr9_-_9992697 0.10 ENSDART00000123415
UDP glucuronosyltransferase 1 family a, b
chr1_-_32111882 0.10 ENSDART00000112639
ENSDART00000101958
patatin-like phospholipase domain containing 4
chr3_+_52145511 0.09 ENSDART00000078485
adhesion G protein-coupled receptor E14
chr13_-_18863680 0.09 ENSDART00000109277
leucine zipper, putative tumor suppressor 2a
chr12_-_35105670 0.09 ENSDART00000153034
si:ch73-127m5.2
chr5_+_25317061 0.09 ENSDART00000170097
transient receptor potential cation channel, subfamily M, member 6
chr16_+_23404170 0.08 ENSDART00000170061
S100 calcium binding protein W
chr16_-_9449712 0.08 ENSDART00000136522
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr24_+_11334733 0.07 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
chr5_-_38107741 0.07 ENSDART00000156853
si:ch211-284e13.14
chr16_+_29586468 0.07 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr22_-_8499778 0.07 ENSDART00000142219
si:ch73-27e22.4
chr2_+_32016256 0.06 ENSDART00000005143
MYC proto-oncogene, bHLH transcription factor b
chr14_+_6429399 0.06 ENSDART00000149783
ENSDART00000148461
ATP-binding cassette, sub-family A (ABC1), member 1B
chr24_+_37370064 0.06 ENSDART00000185870
si:ch211-183d21.3
chr10_-_29733194 0.05 ENSDART00000149252
si:ch73-261i21.2
chr7_+_39011355 0.05 ENSDART00000173855
diacylglycerol kinase, zeta a
chr7_+_4283299 0.05 ENSDART00000182026
kelch-like family member 33
chr2_-_51593835 0.05 ENSDART00000168072
si:ch211-9d9.7
chr17_-_2386569 0.04 ENSDART00000121614
phospholipase C beta 2
chr1_-_11519934 0.04 ENSDART00000162060
sidekick cell adhesion molecule 1b
chr11_+_30960743 0.04 ENSDART00000149597
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr21_+_14511685 0.04 ENSDART00000102099

chr19_-_46777963 0.04 ENSDART00000046857
actin binding Rho activating protein b
chr1_+_30551777 0.04 ENSDART00000112778
G protein-coupled receptor 183b
chr5_-_68259747 0.04 ENSDART00000188756

chr8_-_29677300 0.04 ENSDART00000032407
ENSDART00000143623
perforin 1.6
chr4_-_37479395 0.04 ENSDART00000168299
ENSDART00000157864
si:dkey-106c17.2
chr16_-_21903083 0.04 ENSDART00000165849
SET domain, bifurcated 1b
chr7_+_4922104 0.03 ENSDART00000135154
si:dkey-28d5.11
chr4_+_33012407 0.03 ENSDART00000151873
si:dkey-26h11.2
chr6_-_37460178 0.03 ENSDART00000153500
si:dkey-66a8.7
chr18_+_32444636 0.03 ENSDART00000164223
vomeronasal 2 receptor, a1
chr15_-_20779624 0.03 ENSDART00000181936
tyrosylprotein sulfotransferase 1
chr17_-_44968407 0.03 ENSDART00000165850
neuroglobin
chr19_+_43753995 0.03 ENSDART00000058504
si:ch1073-513e17.1
chr21_+_30662263 0.03 ENSDART00000154758
ENSDART00000138664
chloride channel, voltage-sensitive 5a
chr24_+_20372497 0.03 ENSDART00000132340
ENSDART00000139989
ENSDART00000168751
ENSDART00000192909
phospholipase C, delta 1a
chr22_-_8725594 0.03 ENSDART00000137146
si:ch73-27e22.8
chr17_-_44968177 0.02 ENSDART00000075510
neuroglobin
chr3_-_33961589 0.02 ENSDART00000151533
immunoglobulin heavy constant delta
chr25_+_16043246 0.02 ENSDART00000186663
sb:cb470
chr7_+_73807504 0.02 ENSDART00000166244
si:ch73-252p3.1
chr15_-_31366742 0.02 ENSDART00000125585
odorant receptor, family D, subfamily 111, member 3
chr14_-_2202652 0.02 ENSDART00000171316
si:dkey-262j3.7
chr1_-_2061419 0.02 ENSDART00000058878
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 3
chr1_-_43987873 0.02 ENSDART00000108821

chr22_+_9110998 0.02 ENSDART00000141520
NACHT, LRR and PYD domains-containing protein 15
chr7_+_11390462 0.01 ENSDART00000114383
talin rod domain containing 1
chr1_-_57839070 0.01 ENSDART00000152571
si:dkey-1c7.3
chr1_-_49434798 0.01 ENSDART00000150842
ENSDART00000150789
si:dkeyp-80c12.10
chr12_-_44122412 0.01 ENSDART00000169094
si:ch73-329n5.3
chr16_-_40508624 0.01 ENSDART00000075718
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr19_-_3193912 0.01 ENSDART00000133159
si:ch211-133n4.6
chr5_+_65491390 0.00 ENSDART00000159921
si:dkey-21e5.1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox18

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.0 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.4 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.2 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.5 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.5 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0033335 anal fin development(GO:0033335)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.1 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0006270 DNA replication initiation(GO:0006270)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.5 1.6 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.7 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.5 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE