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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox17

Z-value: 0.52

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_587764000.087.5e-01Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_31854830 0.65 ENSDART00000148550
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_3077395 0.54 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_41717063 0.54 ENSDART00000084610
centrosomal protein 85
chr5_-_67349916 0.53 ENSDART00000144092
MLX interacting protein
chr7_+_38349667 0.52 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr7_-_39378903 0.51 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr3_-_40976288 0.51 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr11_-_44979281 0.50 ENSDART00000190972
LIM-domain binding 1b
chr25_+_3104959 0.50 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr15_-_47468085 0.49 ENSDART00000164438
inositol polyphosphate phosphatase-like 1a
chr9_+_38457806 0.47 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr7_+_66884570 0.47 ENSDART00000082664
SET binding factor 2
chr15_-_37543591 0.47 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr20_+_4222357 0.46 ENSDART00000188331
interaction protein for cytohesin exchange factors 1
chr15_-_37543839 0.46 ENSDART00000148870
lysine (K)-specific methyltransferase 2Bb
chr11_-_27537593 0.45 ENSDART00000173444
ENSDART00000172895
ENSDART00000088177
protein tyrosine phosphatase domain containing 1a
chr2_+_51818039 0.45 ENSDART00000170353
activin A receptor type 2Bb
chr20_+_4221978 0.45 ENSDART00000171898
interaction protein for cytohesin exchange factors 1
chr19_-_18135724 0.44 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr9_-_16218097 0.44 ENSDART00000190503
myosin IB
chr20_-_18794789 0.44 ENSDART00000003834
cerebral cavernous malformation 2
chr3_-_40976463 0.42 ENSDART00000128450
ENSDART00000018676
cytochrome P450, family 3, subfamily c, polypeptide 1
chr22_+_12361317 0.42 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr22_+_12361489 0.40 ENSDART00000182483
R3H domain containing 1
chr13_-_35765028 0.39 ENSDART00000157391
endoplasmic reticulum lectin 1
chr4_-_3145359 0.39 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr3_+_30922947 0.38 ENSDART00000184060
claudin i
chr3_+_35005730 0.37 ENSDART00000029451
protein kinase C, beta b
chr6_+_30533504 0.37 ENSDART00000155842
WWC family member 3
chr17_-_23895026 0.37 ENSDART00000122108
PDZ domain containing 8
chr16_+_50741154 0.37 ENSDART00000101627
zgc:110372
chr21_-_2158298 0.37 ENSDART00000182199
expressed sequence AI877918
chr10_-_3258073 0.36 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr23_+_1414893 0.36 ENSDART00000173020
utrophin
chr1_+_53321878 0.36 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr10_-_8434816 0.34 ENSDART00000108643
tectonic family member 1
chr18_+_38807239 0.33 ENSDART00000184332
family with sequence similarity 214, member A
chr6_+_4299164 0.33 ENSDART00000159759
neurobeachin-like 1
chr2_+_36007449 0.33 ENSDART00000161837
laminin, gamma 2
chr12_-_7253270 0.32 ENSDART00000035762
ubiquitin-conjugating enzyme E2D 1b
chr5_-_69004007 0.32 ENSDART00000137443
ankyrin 1, erythrocytic a
chr5_+_53691803 0.32 ENSDART00000163256
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr1_-_46650022 0.32 ENSDART00000148759
ENSDART00000053222
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr19_-_25114701 0.32 ENSDART00000149035
protein tyrosine phosphatase type IVA, member 3
chr8_+_23147218 0.32 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr23_+_30730121 0.31 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr23_+_24973773 0.31 ENSDART00000047020
caspase 9, apoptosis-related cysteine peptidase
chr19_+_46222428 0.31 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr20_+_40457599 0.31 ENSDART00000017553
serine incorporator 1
chr5_+_51833305 0.31 ENSDART00000165276
ENSDART00000166443
PAP associated domain containing 4
chr10_+_15454745 0.30 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr5_+_51833132 0.30 ENSDART00000167491
PAP associated domain containing 4
chr10_-_7988396 0.30 ENSDART00000141445
ENSDART00000024282
EWS RNA-binding protein 1a
chr16_-_28658341 0.30 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr15_+_20344670 0.30 ENSDART00000158986
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_-_7107868 0.30 ENSDART00000171123
nonhomologous end-joining factor 1
chr2_+_26240631 0.29 ENSDART00000129895
paralemmin 1b
chr23_-_24542156 0.29 ENSDART00000132265
ATPase 13A2
chr8_-_44611357 0.29 ENSDART00000063396
BCL2 associated athanogene 4
chr21_+_6328801 0.29 ENSDART00000163577
formin binding protein 1b
chr5_-_68495967 0.29 ENSDART00000188107
eph receptor B4a
chr21_+_12036238 0.29 ENSDART00000102463
ENSDART00000155426
zgc:162344
chr4_-_2975461 0.29 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr6_+_55428924 0.29 ENSDART00000018270
nuclear receptor coactivator 5
chr19_+_27970292 0.29 ENSDART00000103887
ENSDART00000145549
mediator complex subunit 10
chr18_-_46183462 0.28 ENSDART00000021192
potassium channel, subfamily K, member 6
chr2_+_22409249 0.28 ENSDART00000182915
zgc:56628
chr13_-_31687925 0.28 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr22_-_14161309 0.28 ENSDART00000133365
si:ch211-246m6.5
chr24_-_16979728 0.28 ENSDART00000005331
kelch-like family member 15
chr5_-_15264007 0.27 ENSDART00000180641
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr5_+_36896933 0.27 ENSDART00000151984
serine/arginine-rich splicing factor 7a
chr17_+_13031497 0.27 ENSDART00000115208
F-box protein 33
chr15_-_30984804 0.27 ENSDART00000157005
neurofibromin 1a
chr20_+_18945057 0.27 ENSDART00000035447
myotubularin related protein 9
chr8_+_23147609 0.27 ENSDART00000180284
GID complex subunit 8 homolog a (S. cerevisiae)
chr13_+_31687973 0.27 ENSDART00000076479
solute carrier family 38, member 6
chr12_+_29240124 0.27 ENSDART00000053761
ENSDART00000130172
BMS1 ribosome biogenesis factor
chr7_-_30624435 0.26 ENSDART00000173828
ring finger protein 111
chr13_+_18659325 0.26 ENSDART00000147905
ENSDART00000188249
ENSDART00000134740
selenoprotein U 1a
chr12_-_611367 0.26 ENSDART00000152286
wu:fj29h11
chr15_-_28904371 0.26 ENSDART00000155154
echinoderm microtubule associated protein like 2
chr17_+_50127648 0.26 ENSDART00000156460
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr13_-_9367647 0.26 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
chr14_+_16036139 0.26 ENSDART00000190733
PRELI domain containing 1a
chr3_-_39363065 0.26 ENSDART00000155894
Rho GTPase activating protein 23a
chr12_-_30032188 0.26 ENSDART00000042514
attractin-like 1b
chr10_-_28513861 0.25 ENSDART00000177781
bobby sox homolog (Drosophila)
chr15_-_2803313 0.25 ENSDART00000060839
transforming growth factor, beta 1a
chr1_+_46405294 0.25 ENSDART00000143228
tubulin, gamma complex associated protein 3
chr23_+_16774589 0.25 ENSDART00000104791
zgc:153722
chr4_-_3064101 0.25 ENSDART00000135701
pleckstrin homology domain containing, family A member 5
chr5_+_24086227 0.25 ENSDART00000051549
ENSDART00000177458
ENSDART00000135934
tumor protein p53
chr19_-_20446756 0.24 ENSDART00000140711
TBC1 domain family, member 5
chr13_-_533243 0.24 ENSDART00000038315
nuclear VCP-like
chr17_+_24222190 0.24 ENSDART00000181698
ENSDART00000189411
EH domain binding protein 1
chr7_+_29962559 0.24 ENSDART00000075538
F-box protein 22
chr7_-_24204200 0.24 ENSDART00000087298
guanosine monophosphate reductase 2
chr10_-_6588793 0.24 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr4_-_18416566 0.24 ENSDART00000033717
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_46404968 0.24 ENSDART00000042064
tubulin, gamma complex associated protein 3
chr25_+_23358924 0.24 ENSDART00000156965
oxysterol binding protein-like 5
chr21_+_24536233 0.23 ENSDART00000145448
ENSDART00000109886
ENSDART00000135191
anaphase promoting complex subunit 13
chr20_-_31238313 0.23 ENSDART00000028471
hippocalcin-like 1
chr18_-_21725805 0.23 ENSDART00000182185
FANCD2/FANCI-associated nuclease 1
chr18_+_20560616 0.23 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr11_-_22361306 0.23 ENSDART00000180688
ENSDART00000182200
ENSDART00000006580
transcription factor EB
chr11_+_30636351 0.22 ENSDART00000087909
transmembrane protein 246
chr7_-_28641522 0.22 ENSDART00000182071
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr19_-_24136233 0.22 ENSDART00000143365
THAP domain containing 7
chr10_-_22845485 0.22 ENSDART00000079454
vesicle-associated membrane protein 2
chr18_-_21725638 0.21 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr8_-_22326073 0.21 ENSDART00000084965
centrosomal protein 104
chr13_-_48431766 0.21 ENSDART00000159688
ENSDART00000171765
F-box protein 11a
chr24_+_41281265 0.21 ENSDART00000156920
ENSDART00000155151
negative regulator of ubiquitin-like proteins 1
chr4_-_28353538 0.21 ENSDART00000064219
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr7_-_40122139 0.21 ENSDART00000173982
si:ch73-174h16.5
chr21_+_33503835 0.20 ENSDART00000125658
clathrin interactor 1b
chr23_-_36670369 0.20 ENSDART00000006881
zinc finger and BTB domain containing 39
chr1_+_49878000 0.20 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr22_+_1868983 0.20 ENSDART00000160135
si:dkey-15h8.17
chr22_+_28818291 0.20 ENSDART00000136032
tumor protein p53 binding protein, 2b
chr17_-_13070602 0.20 ENSDART00000188311
ENSDART00000193428

chr7_+_10562118 0.20 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr6_-_8392104 0.20 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr17_+_16423721 0.20 ENSDART00000064233
EF-hand calcium binding domain 11
chr2_+_43204919 0.19 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr21_-_7178348 0.19 ENSDART00000187467
family with sequence similarity 69, member B
chr18_+_1837668 0.19 ENSDART00000164210

chr7_-_64770456 0.19 ENSDART00000192618
zinc finger, DHHC-type containing 21
chr12_+_19958845 0.19 ENSDART00000193248
excision repair cross-complementation group 4
chr8_-_9684872 0.19 ENSDART00000132158
protein tyrosine phosphatase, non-receptor type 18
chr17_-_5769196 0.18 ENSDART00000113885
si:dkey-100n19.2
chr19_+_42886413 0.18 ENSDART00000151298
cAMP-regulated phosphoprotein, 21
chr3_-_39190317 0.18 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr11_+_42494531 0.18 ENSDART00000067604
ADP-ribosylation factor 4a
chr1_+_29766725 0.18 ENSDART00000054064
zinc finger CCCH-type containing 13
chr16_-_27138478 0.17 ENSDART00000147438
transmembrane protein 245
chr10_-_28027490 0.17 ENSDART00000185445
integrator complex subunit 2
chr1_-_23110740 0.17 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr6_-_1591002 0.17 ENSDART00000087039
zgc:123305
chr23_+_32101361 0.17 ENSDART00000138849
zgc:56699
chr23_+_25201077 0.17 ENSDART00000136675
si:dkey-151g10.3
chr21_-_20381481 0.16 ENSDART00000115236
ATP synthase membrane subunit ea
chr16_+_35905031 0.16 ENSDART00000162411
SH3 domain containing 21
chr25_-_31907590 0.16 ENSDART00000149707
ENSDART00000149471
eukaryotic translation initiation factor 3, subunit Ja
chr10_+_36662640 0.16 ENSDART00000063359
uncoupling protein 2
chr5_-_8602937 0.16 ENSDART00000157765
RPTOR independent companion of MTOR, complex 2 a
chr6_+_54498220 0.15 ENSDART00000103282
si:ch211-233f11.5
chr14_+_29609245 0.15 ENSDART00000043058
si:dkey-34l15.2
chr9_+_16854121 0.15 ENSDART00000110866
CLN5, intracellular trafficking protein
chr11_-_42134968 0.15 ENSDART00000187115

chr2_+_55199721 0.15 ENSDART00000016143
zmp:0000000521
chr17_+_51520073 0.15 ENSDART00000189646
ENSDART00000170951
ENSDART00000189492
peroxidasin
chr9_-_46276626 0.15 ENSDART00000165238
histone deacetylase 4
chr24_-_33284945 0.14 ENSDART00000155429
ENSDART00000112845
zgc:195173
chr14_+_6954579 0.14 ENSDART00000060998
NME/NM23 family member 5
chr11_-_30636163 0.14 ENSDART00000140516
zgc:153665
chr25_+_20694177 0.14 ENSDART00000073648
KxDL motif containing 1
chr5_-_20678300 0.14 ENSDART00000088639
WSC domain containing 2
chr16_+_28764017 0.14 ENSDART00000122433
tripartite motif containing 33, like
chr1_-_44704261 0.14 ENSDART00000133210
si:dkey-28b4.8
chr25_-_7686201 0.14 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
chr2_+_24867534 0.14 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr13_+_6189203 0.13 ENSDART00000109665
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr9_+_21146862 0.13 ENSDART00000136365
hydroxyacid oxidase 2 (long chain)
chr16_+_25074029 0.13 ENSDART00000155465
si:dkeyp-84f3.9
chr6_+_6780873 0.13 ENSDART00000011865
Sec23 homolog B, COPII coat complex component
chr2_-_26596794 0.13 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr6_-_12314475 0.13 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
chr14_-_25956804 0.13 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr4_+_25693463 0.12 ENSDART00000132864
acyl-CoA thioesterase 18
chr7_+_23495986 0.12 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr5_-_33769211 0.12 ENSDART00000133504
DAB2 interacting protein b
chr21_-_39628771 0.12 ENSDART00000183995
aldolase C, fructose-bisphosphate, b
chr5_-_69314495 0.12 ENSDART00000182335
smoothelin b
chr16_+_28994709 0.12 ENSDART00000088023
gon-4-like (C. elegans)
chr5_+_59278193 0.12 ENSDART00000160025
RAS p21 protein activator 4
chr18_+_31117323 0.12 ENSDART00000059893
transcription factor 25 (basic helix-loop-helix)
chr5_-_54790923 0.12 ENSDART00000176835
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_-_11493236 0.12 ENSDART00000002691
tetraspanin 7b
chr18_+_619619 0.12 ENSDART00000159846
protogenin homolog a (Gallus gallus)
chr24_+_26997798 0.11 ENSDART00000089506
La ribonucleoprotein domain family, member 4B
chr13_-_45201300 0.11 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr20_+_28803977 0.11 ENSDART00000153351
ENSDART00000038149
farnesyltransferase, CAAX box, beta
chr18_+_31117136 0.11 ENSDART00000138403
transcription factor 25 (basic helix-loop-helix)
chr7_-_32020100 0.11 ENSDART00000185433
kinesin family member 18A
chr1_-_656693 0.11 ENSDART00000170483
ENSDART00000166786
amyloid beta (A4) precursor protein a
chr3_+_18795570 0.10 ENSDART00000042368
fumarylacetoacetate hydrolase domain containing 1
chr20_+_32224405 0.10 ENSDART00000062993
ENSDART00000147448
sestrin 1
chr9_-_32813177 0.10 ENSDART00000012694
myxovirus (influenza virus) resistance C
chr1_-_18772241 0.10 ENSDART00000147645
ENSDART00000133194
ENSDART00000147525
ENSDART00000191493
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr25_+_19485198 0.10 ENSDART00000156730
glutaminase like
chr25_-_21894706 0.10 ENSDART00000189158
F-box protein 31
chr8_+_10339869 0.10 ENSDART00000132253
TBC1 domain family, member 22B
chr14_+_36246726 0.10 ENSDART00000105602
ELOVL fatty acid elongase 6
chr20_-_48898371 0.10 ENSDART00000170617
5'-3' exoribonuclease 2
chr4_+_9030609 0.10 ENSDART00000154399
aldehyde dehydrogenase 1 family, member L2
chr6_-_43092175 0.10 ENSDART00000084389
leucine rich repeat neuronal 1
chr7_-_35314347 0.10 ENSDART00000005053
solute carrier family 12 (potassium/chloride transporter), member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.2 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.5 GO:0090024 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.2 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.5 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0048785 hatching gland development(GO:0048785)
0.0 0.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling