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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox11a+sox11b

Z-value: 0.80

Motif logo

Transcription factors associated with sox11a+sox11b

Gene Symbol Gene ID Gene Info
ENSDARG00000077811 SRY-box transcription factor 11a
ENSDARG00000095743 SRY-box transcription factor 11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox11bdr11_v1_chr20_-_30035326_30035326-0.791.1e-04Click!
sox11adr11_v1_chr17_-_35881841_358818410.719.4e-04Click!

Activity profile of sox11a+sox11b motif

Sorted Z-values of sox11a+sox11b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_3118346 1.51 ENSDART00000167554
heat shock transcription factor family member 5
chrM_+_6425 1.44 ENSDART00000093606
cytochrome c oxidase I, mitochondrial
chr10_+_2587234 1.25 ENSDART00000126937
wu:fb59d01
chr8_+_34434345 1.09 ENSDART00000190246
ENSDART00000189447
ENSDART00000185557
ENSDART00000189230
zgc:174461
chr5_+_66353750 1.06 ENSDART00000143410
si:ch211-261c8.5
chr23_+_12198242 1.03 ENSDART00000144104
synaptonemal complex protein 2
chr12_-_19279103 0.92 ENSDART00000186669
si:ch211-141o9.10
chr20_+_33519435 0.92 ENSDART00000061829
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chrM_+_12897 0.91 ENSDART00000093622
NADH dehydrogenase 5, mitochondrial
chr16_-_23346095 0.89 ENSDART00000160546
si:dkey-247k7.2
chr7_-_22981796 0.89 ENSDART00000167565
si:dkey-171c9.3
chr13_+_24755049 0.88 ENSDART00000134102
collagen, type XVII, alpha 1b
chr6_-_57539141 0.84 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr11_-_25734417 0.83 ENSDART00000103570
bromodomain and PHD finger containing, 3a
chr2_-_1569250 0.83 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr16_+_54263921 0.81 ENSDART00000002856
dopamine receptor D2 like
chr7_-_40145097 0.79 ENSDART00000173634
WD repeat domain 60
chr7_-_58729894 0.78 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7
chr18_+_5547185 0.72 ENSDART00000193977
nicotinamide nucleotide transhydrogenase 2
chr13_+_13693722 0.72 ENSDART00000110509
si:ch211-194c3.5
chr2_+_16780643 0.71 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
transferrin-a
chr11_-_25733910 0.69 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr10_+_6884123 0.67 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr21_-_41305748 0.67 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr19_+_26718074 0.64 ENSDART00000134455
zgc:100906
chr5_+_41996889 0.64 ENSDART00000097580
phosphatidylinositol glycan anchor biosynthesis, class L
chr10_+_6884627 0.63 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr25_-_3647277 0.62 ENSDART00000166363
si:ch211-272n13.3
chr25_-_7764083 0.62 ENSDART00000179800
ENSDART00000181858
PHD finger protein 21Ab
chr10_+_41668483 0.60 ENSDART00000127073
leucine rich repeat containing 75Bb
chr20_+_26538137 0.60 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr14_+_4151379 0.60 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr11_-_33612433 0.59 ENSDART00000179756
LIM and senescent cell antigen-like domains 1
chr2_+_9061885 0.59 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr1_-_20928772 0.57 ENSDART00000078277
methylsterol monooxygenase 1
chr3_+_26267725 0.53 ENSDART00000131288
ArfGAP with dual PH domains 2
chr18_-_43884044 0.52 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr5_+_69716458 0.52 ENSDART00000159594
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr23_+_31815423 0.50 ENSDART00000075730
ENSDART00000075726
v-myb avian myeloblastosis viral oncogene homolog
chr3_-_23643751 0.49 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr2_-_40135942 0.48 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr10_-_28761454 0.46 ENSDART00000129400
activated leukocyte cell adhesion molecule a
chr15_-_45510977 0.46 ENSDART00000090596
fibroblast growth factor 12b
chr16_+_18535618 0.43 ENSDART00000021596
retinoid x receptor, beta b
chr4_-_18635005 0.43 ENSDART00000125361
peroxisome proliferator-activated receptor alpha a
chr1_+_26445615 0.41 ENSDART00000180810
GTPase activating protein (SH3 domain) binding protein 2
chr24_-_41220538 0.41 ENSDART00000150207
activin A receptor type 2Ba
chr9_+_22657221 0.41 ENSDART00000101765
si:dkey-189g17.2
chr25_+_19041329 0.40 ENSDART00000153467
leucine-rich repeats and transmembrane domains 2b
chr16_-_43233509 0.39 ENSDART00000025877
claudin 12
chr24_+_26345609 0.39 ENSDART00000186844
leucine rich repeat containing 34
chr10_-_41906609 0.38 ENSDART00000102530
lysine (K)-specific demethylase 2Bb
chr2_-_23411368 0.38 ENSDART00000159495
si:ch73-129a22.11
chr1_+_26444986 0.37 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr19_-_31402429 0.37 ENSDART00000137292
transmembrane protein 106Bb
chr12_-_37734973 0.36 ENSDART00000140353
sidekick cell adhesion molecule 2b
chr1_+_21309386 0.36 ENSDART00000054442
ENSDART00000145661
mediator complex subunit 28
chr7_+_22981909 0.35 ENSDART00000122449
cyclin B3
chr12_-_11258404 0.35 ENSDART00000149229
si:ch73-30l9.1
chr10_-_41907213 0.34 ENSDART00000167004
lysine (K)-specific demethylase 2Bb
chr16_+_36768674 0.34 ENSDART00000169208
ENSDART00000180470
si:ch73-215d9.1
chr23_+_23022790 0.34 ENSDART00000189843
sterile alpha motif domain containing 11
chr13_-_45201300 0.33 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr15_-_2841677 0.33 ENSDART00000026145
ENSDART00000180290
angiomotin like 1
chr19_-_18135724 0.33 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr24_-_38657683 0.32 ENSDART00000154843
si:ch1073-164k15.3
chr20_-_31067306 0.32 ENSDART00000014163
fibronectin type III domain containing 1
chr16_-_21140097 0.32 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
chr22_+_37902976 0.32 ENSDART00000169327
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr19_-_10915898 0.31 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr5_-_26118855 0.31 ENSDART00000009028
elastase 3 like
chr5_-_38342992 0.30 ENSDART00000140337
misshapen-like kinase 1
chr22_+_10440991 0.30 ENSDART00000064805
centromere protein P
chr5_-_24869213 0.30 ENSDART00000112287
ENSDART00000144635
growth arrest-specific 2 like 1
chr5_-_67911111 0.30 ENSDART00000051833
GS homeobox 1
chr23_-_31403668 0.29 ENSDART00000147498

chr16_-_22006996 0.29 ENSDART00000116114
si:dkey-71b5.7
chr25_+_35058088 0.29 ENSDART00000156838
zgc:112234
chr19_-_9522548 0.28 ENSDART00000045245
inhibitor of growth family, member 4
chr17_-_24439672 0.28 ENSDART00000155020
WD repeat containing planar cell polarity effector
chr7_+_22982201 0.26 ENSDART00000134116
cyclin B3
chr23_+_40460333 0.26 ENSDART00000184658
SOGA family member 3b
chr21_-_30254185 0.26 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr8_-_39822917 0.26 ENSDART00000067843
zgc:162025
chr24_-_37680917 0.26 ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr11_+_36355348 0.26 ENSDART00000145427
synaptophysin-like 2a
chr22_+_7439186 0.26 ENSDART00000190667
zgc:92041
chr15_-_40267485 0.25 ENSDART00000152253
potassium inwardly-rectifying channel, subfamily J, member 13
chr4_-_52165969 0.25 ENSDART00000171130
si:dkeyp-44b5.4
chr19_-_5369486 0.24 ENSDART00000105004
keratin 17
chr8_+_8671229 0.24 ENSDART00000131963
ubiquitin specific peptidase 11
chr1_-_23596391 0.24 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr1_-_35924495 0.24 ENSDART00000184424
SMAD family member 1
chr5_+_26795465 0.23 ENSDART00000053001
transcobalamin II
chr24_-_26302375 0.23 ENSDART00000130696
COP9 signalosome subunit 9
chr2_+_24177006 0.22 ENSDART00000132582
microtubule associated protein 4 like
chr3_+_19299309 0.22 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr7_-_35314347 0.22 ENSDART00000005053
solute carrier family 12 (potassium/chloride transporter), member 4
chr5_+_66433287 0.21 ENSDART00000170757
kinetochore associated 1
chr14_+_44794936 0.21 ENSDART00000128881
zgc:195212
chr15_-_20949692 0.21 ENSDART00000185548
tubulin folding cofactor E-like a
chr19_-_6083761 0.20 ENSDART00000151185
ENSDART00000143941
glycogen synthase kinase 3 alpha a
chr6_+_4229360 0.20 ENSDART00000191347
ENSDART00000130642

chr4_+_28374628 0.19 ENSDART00000076037
asparagine-linked glycosylation 10
chr21_+_11401247 0.19 ENSDART00000143952
carboxyl ester lipase, tandem duplicate 1
chr6_+_39812475 0.19 ENSDART00000067063
complement component 1, q subcomponent-like 4b
chr16_-_17072440 0.19 ENSDART00000002493
ENSDART00000178443
tumor necrosis factor receptor superfamily, member 1a
chr6_-_40195510 0.19 ENSDART00000156156
collagen, type VII, alpha 1
chr5_+_3118231 0.18 ENSDART00000179809
SPT4 homolog, DSIF elongation factor subunit
chr10_+_25204626 0.18 ENSDART00000024514
cysteine and histidine-rich domain (CHORD) containing 1b
chr5_-_61431809 0.18 ENSDART00000082952
RCC1 like
chr11_-_30158191 0.18 ENSDART00000155278
ENSDART00000156121
Scm polycomb group protein like 2
chr2_+_22659787 0.18 ENSDART00000043956
zgc:161973
chr13_-_1349922 0.17 ENSDART00000140970
si:ch73-52p7.1
chr2_+_904362 0.17 ENSDART00000024967
receptor (TNFRSF)-interacting serine-threonine kinase 1, like
chr2_+_24177190 0.17 ENSDART00000099546
microtubule associated protein 4 like
chr1_+_46948010 0.17 ENSDART00000132843
si:dkey-22n8.2
chr20_-_47188966 0.17 ENSDART00000152965
si:dkeyp-104f11.9
chr25_+_19485198 0.16 ENSDART00000156730
glutaminase like
chr4_+_69823638 0.16 ENSDART00000165786
zinc finger protein 1087
chr19_+_37509638 0.16 ENSDART00000139999
si:ch211-250g4.3
chr22_+_17606863 0.15 ENSDART00000035670
polymerase (RNA) II (DNA directed) polypeptide E, b
chr22_+_7462997 0.15 ENSDART00000106082
zgc:112368
chr16_-_33001153 0.15 ENSDART00000147941
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_16153207 0.15 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr23_+_4226341 0.14 ENSDART00000012445
zgc:113278
chr16_+_40217043 0.14 ENSDART00000191128

chr15_-_15357178 0.14 ENSDART00000106120
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr1_-_23595779 0.14 ENSDART00000134860
ENSDART00000138852
ligand dependent nuclear receptor corepressor-like
chr4_+_14957360 0.13 ENSDART00000002770
ENSDART00000111882
ENSDART00000148292
tetraspanin 33a
chr5_+_10084100 0.13 ENSDART00000109236
si:ch211-207k7.4
chr12_+_47663419 0.13 ENSDART00000171932
hematopoietically expressed homeobox
chr17_+_33340675 0.13 ENSDART00000184396
ENSDART00000077553
xanthine dehydrogenase
chr11_-_1409236 0.12 ENSDART00000121537
si:ch211-266k22.6
chr7_+_57108823 0.12 ENSDART00000184943
ENSDART00000055956
enolase superfamily member 1
chr15_+_11840311 0.12 ENSDART00000167671
protein kinase D2
chr5_-_66301142 0.12 ENSDART00000067541
prolactin receptor b
chr17_-_48915427 0.12 ENSDART00000054781
galectin 8b
chr9_+_35014513 0.12 ENSDART00000100701
GA binding protein transcription factor, alpha subunit
chr17_-_39185336 0.12 ENSDART00000050534
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr25_+_17920361 0.12 ENSDART00000185644
BLOC-1 related complex subunit 5
chr23_-_17657348 0.11 ENSDART00000054736
basic helix-loop-helix family, member e23
chr18_+_30028637 0.11 ENSDART00000139750
si:ch211-220f16.1
chr21_-_45363871 0.11 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
zgc:56064
chr16_-_44878245 0.10 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
Rho GTPase activating protein 33
chr1_-_54765262 0.10 ENSDART00000150362
si:ch211-197k17.3
chr9_+_32859967 0.10 ENSDART00000168992
si:dkey-145p14.5
chr20_-_38836161 0.10 ENSDART00000061358
si:dkey-221h15.4
chr8_-_5220125 0.09 ENSDART00000035676
BCL2 interacting protein 3 like a
chr11_+_30513656 0.09 ENSDART00000008594
transmembrane protein 178
chr17_+_2727807 0.09 ENSDART00000178759
potassium channel, subfamily K, member 10b
chr20_-_34663209 0.09 ENSDART00000132545
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_12930217 0.09 ENSDART00000166322
platelet-derived growth factor alpha polypeptide b
chr23_-_6865946 0.09 ENSDART00000056426
finTRIM family, member 58
chr8_+_24861264 0.08 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr2_-_57344037 0.08 ENSDART00000148873
transcription factor 3a
chr19_+_26072624 0.08 ENSDART00000147627
jumonji, AT rich interactive domain 2b
chr6_+_54538948 0.08 ENSDART00000149270
tubby like protein 1b
chr5_+_63857055 0.08 ENSDART00000138950
regulator of G protein signaling 3b
chr1_-_36152131 0.07 ENSDART00000182113
ENSDART00000182904
zinc finger protein 827
chr13_+_35637048 0.07 ENSDART00000085037
thrombospondin 2a
chr6_-_1768724 0.07 ENSDART00000162488
ENSDART00000163613
zgc:158417
chr18_+_3579829 0.06 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr13_+_10023256 0.06 ENSDART00000110035
S1 RNA binding domain 1
chr19_-_24224142 0.06 ENSDART00000136409
ENSDART00000114390
perforin 1.8
chr15_+_17251191 0.06 ENSDART00000156587
si:ch73-223p23.2
chr5_-_11905920 0.06 ENSDART00000114378
F-box and WD repeat domain containing 8
chr25_+_19695652 0.06 ENSDART00000104340
myxovirus (influenza virus) resistance G
chr8_+_23784471 0.06 ENSDART00000189457
si:ch211-163l21.8
chr10_-_21953643 0.06 ENSDART00000188921
ENSDART00000193569

chr20_+_9128829 0.06 ENSDART00000064144
ENSDART00000137450
bisphosphate nucleotidase 1
chr3_+_22375596 0.06 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr14_-_17576662 0.05 ENSDART00000193893
ring finger protein 4
chr25_+_14087045 0.05 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr8_-_50888806 0.05 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr7_+_10562118 0.05 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr2_-_26509057 0.05 ENSDART00000139169
ENSDART00000181777
bestrophin 4
chr3_+_22270463 0.05 ENSDART00000104004
sodium channel, voltage-gated, type IV, alpha, b
chr5_-_51484156 0.05 ENSDART00000162064

chr10_+_17714866 0.05 ENSDART00000039969
solute carrier family 20 (phosphate transporter), member 1b
chr22_+_3238474 0.04 ENSDART00000157954
si:ch1073-178p5.3
chr6_+_39098397 0.04 ENSDART00000003716
ENSDART00000188655
protease, serine, 60.2
chr6_-_27108844 0.04 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr6_-_50704689 0.04 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr14_+_8715527 0.04 ENSDART00000170754
potassium channel, subfamily K, member 4a
chr20_-_47731768 0.04 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr19_-_42588510 0.03 ENSDART00000102583
synaptotagmin-like 1
chr22_-_6991514 0.03 ENSDART00000148233
fibroblast growth factor receptor 1b, like
chr21_-_18648861 0.03 ENSDART00000112113
si:dkey-112m2.1
chr20_+_37295006 0.03 ENSDART00000153137
connexin 23
chr12_-_44010532 0.03 ENSDART00000183875
si:ch211-182p11.1
chr1_-_35695614 0.02 ENSDART00000133813
ENSDART00000145291
ENSDART00000176451
si:dkey-27h10.2
chr25_-_20691609 0.02 ENSDART00000186942
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr12_-_20665164 0.02 ENSDART00000105352
gastric inhibitory polypeptide
chr3_+_18425814 0.02 ENSDART00000144222
glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)
chr9_-_18568927 0.02 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr20_+_16703050 0.02 ENSDART00000005244
potassium channel, subfamily K, member 13b
chr9_+_19039608 0.02 ENSDART00000055866
charged multivesicular body protein 2Ba
chr16_-_52540056 0.02 ENSDART00000188304

chr16_+_23087326 0.02 ENSDART00000167518
ENSDART00000161087
ephrin-A3b

Network of associatons between targets according to the STRING database.

First level regulatory network of sox11a+sox11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.2 0.7 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.9 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 1.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 0.2 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.5 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.8 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.3 GO:0097065 anterior head development(GO:0097065)
0.1 0.3 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.5 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.6 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.6 GO:0060324 face development(GO:0060324)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.0 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.5 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0097541 axonemal basal plate(GO:0097541)
0.1 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.9 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0043186 P granule(GO:0043186)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.5 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 1.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo