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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for snai2

Z-value: 0.41

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Transcription factors associated with snai2

Gene Symbol Gene ID Gene Info
ENSDARG00000040046 snail family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
snai2dr11_v1_chr24_+_35387517_353875170.857.2e-06Click!

Activity profile of snai2 motif

Sorted Z-values of snai2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_1052591 1.27 ENSDART00000123405
unc-5 netrin receptor C
chr2_+_26237322 0.92 ENSDART00000030520
paralemmin 1b
chr14_+_15155684 0.91 ENSDART00000167966
zgc:158852
chr20_-_3238110 0.91 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr15_+_20239141 0.90 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr10_+_6340478 0.86 ENSDART00000163182
ENSDART00000163722
tropomyosin 2 (beta)
chr9_-_28255029 0.85 ENSDART00000160387
cyclin Y-like 1
chr12_-_4243268 0.82 ENSDART00000131275
zgc:92313
chr23_+_2728095 0.79 ENSDART00000066086
zgc:114123
chr6_-_37749711 0.78 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr19_+_791538 0.75 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr18_+_45666489 0.74 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr23_+_27778670 0.74 ENSDART00000053863
lysine (K)-specific methyltransferase 2D
chr7_-_33868903 0.73 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr21_-_21178410 0.73 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr20_-_23253630 0.72 ENSDART00000103365
OCIA domain containing 1
chr6_+_1724889 0.69 ENSDART00000157415
activin A receptor type 2Ab
chr20_-_41992878 0.68 ENSDART00000100967
si:dkeyp-114g9.1
chr14_+_30285613 0.68 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr5_+_6670945 0.67 ENSDART00000185686
paxillin a
chr13_-_36525982 0.66 ENSDART00000114744
phosphofurin acidic cluster sorting protein 2
chr3_+_43086548 0.66 ENSDART00000163579
si:dkey-43p13.5
chr17_-_24575893 0.66 ENSDART00000141914
aftiphilin b
chr20_+_21268795 0.64 ENSDART00000090016
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr8_-_38022298 0.63 ENSDART00000067809
RAB11 family interacting protein 1 (class I) a
chr7_-_51773166 0.63 ENSDART00000054591
bone morphogenetic protein 15
chr5_+_22974019 0.63 ENSDART00000147157
ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr7_-_53117131 0.62 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr21_-_35325466 0.62 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ubiquitin-like domain containing CTD phosphatase 1
chr23_-_44574059 0.62 ENSDART00000123007
si:ch73-160p18.3
chr19_-_18313303 0.62 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr23_+_27779452 0.61 ENSDART00000134785
lysine (K)-specific methyltransferase 2D
chr5_+_36654817 0.59 ENSDART00000131339
calpain, small subunit 1 a
chr15_+_784149 0.57 ENSDART00000155114
zinc finger protein 970
chr1_-_24349759 0.57 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr3_-_30888415 0.56 ENSDART00000124458
lysine methyltransferase 5C
chr21_-_43666420 0.54 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr8_-_1698155 0.53 ENSDART00000186159

chr4_+_26053044 0.53 ENSDART00000039877
si:ch211-244b2.1
chr11_-_43473824 0.52 ENSDART00000179561
transmembrane protein 63Bb
chr2_-_15040345 0.51 ENSDART00000109657
si:dkey-10f21.4
chr3_-_32362872 0.51 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr9_+_45428041 0.50 ENSDART00000193087
adenosine deaminase, RNA-specific, B1b
chr16_+_41060161 0.50 ENSDART00000141130
SREBF chaperone
chr14_-_21618005 0.49 ENSDART00000043162
receptor accessory protein 2
chr17_+_1360192 0.48 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr23_+_39963599 0.48 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr19_-_15229421 0.48 ENSDART00000055619
phosphatase and actin regulator 4a
chr2_-_58075414 0.48 ENSDART00000161920
nectin cell adhesion molecule 4
chr13_+_34689663 0.47 ENSDART00000133661
taspase, threonine aspartase, 1
chr14_+_989733 0.47 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr5_-_54712159 0.47 ENSDART00000149207
cyclin B1
chr1_-_59313465 0.47 ENSDART00000158067
ENSDART00000159419
thioredoxin domain containing 11
chr3_-_34528306 0.47 ENSDART00000023039
septin 9a
chr7_+_30988570 0.46 ENSDART00000180613
ENSDART00000185625
tight junction protein 1a
chr22_-_12304591 0.46 ENSDART00000136408
zinc finger, RAN-binding domain containing 3
chr1_+_53321878 0.45 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr9_-_28990649 0.45 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr5_+_44655148 0.45 ENSDART00000124059
death-associated protein kinase 1
chr6_+_58289335 0.45 ENSDART00000177399
Ral GTPase activating protein, beta subunit (non-catalytic)
chr13_-_4134141 0.44 ENSDART00000132354
tight junction associated protein 1 (peripheral)
chr9_+_45493341 0.44 ENSDART00000145616
adenosine deaminase, RNA-specific, B1b
chr18_+_6641542 0.44 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr5_-_57204352 0.44 ENSDART00000171252
ENSDART00000180727
mannosidase, alpha, class 2A, member 1
chr24_-_31904924 0.43 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr20_+_54336137 0.43 ENSDART00000113792
CLOCK-interacting pacemaker b
chr20_-_43743700 0.42 ENSDART00000100620
si:dkeyp-50f7.2
chr7_+_24528430 0.40 ENSDART00000133022
si:dkeyp-75h12.2
chr10_+_37173029 0.40 ENSDART00000136510
kinase suppressor of ras 1a
chr15_-_19128705 0.39 ENSDART00000152428
Rho GTPase activating protein 32a
chr13_+_7578111 0.38 ENSDART00000175431
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr23_+_26026383 0.38 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_-_7234915 0.38 ENSDART00000048866
inositol polyphosphate multikinase b
chr1_-_40341306 0.37 ENSDART00000190649
mastermind-like transcriptional coactivator 3
chr11_-_11791718 0.37 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr10_+_5954787 0.36 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr16_-_31791165 0.36 ENSDART00000148389
chromodomain helicase DNA binding protein 4b
chr18_-_26781616 0.36 ENSDART00000136776
ENSDART00000076484
KTI12 chromatin associated homolog
chr23_-_32156278 0.35 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr10_+_19596214 0.35 ENSDART00000183110

chr14_-_15155384 0.35 ENSDART00000172666
UV-stimulated scaffold protein A
chr13_-_36050303 0.35 ENSDART00000134955
ENSDART00000139087
legumain
chr1_+_46493944 0.34 ENSDART00000114083
mcf.2 cell line derived transforming sequence-like a
chr17_-_25331439 0.34 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr13_+_2448251 0.34 ENSDART00000188361
ARFGEF family member 3
chr6_-_55399214 0.34 ENSDART00000168367
cathepsin A
chr24_+_36018164 0.33 ENSDART00000182815
ENSDART00000126941
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2
chr18_-_38271298 0.33 ENSDART00000143016
cell cycle associated protein 1b
chr5_+_18014931 0.33 ENSDART00000142562
activating signal cointegrator 1 complex subunit 2
chr21_-_4250682 0.33 ENSDART00000099389
DNL-type zinc finger
chr6_+_12482599 0.33 ENSDART00000090316
serine/threonine kinase 24b (STE20 homolog, yeast)
chr4_-_12978925 0.32 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr17_+_50655619 0.32 ENSDART00000184917
ENSDART00000167638
DDHD domain containing 1a
chr1_+_10019653 0.31 ENSDART00000190227
tripartite motif containing 2b
chr2_+_23677179 0.31 ENSDART00000153918
oxidative stress responsive 1a
chr3_+_1179601 0.31 ENSDART00000173378
TRIO and F-actin binding protein b
chr1_+_24469313 0.31 ENSDART00000176581
family with sequence similarity 160, member A1a
chr22_+_30195257 0.31 ENSDART00000027803
ENSDART00000172496
adducin 3 (gamma) a
chr4_-_17263210 0.31 ENSDART00000147853
lymphoid-restricted membrane protein
chr15_+_38221038 0.31 ENSDART00000188149
stromal interaction molecule 1a
chr1_-_7673376 0.30 ENSDART00000013264
arginine and glutamate rich 1b
chr16_-_19568795 0.30 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr20_+_36806398 0.29 ENSDART00000153317
ABRA C-terminal like
chr11_+_6902946 0.29 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr11_-_25853212 0.28 ENSDART00000145655
transmembrane protein 51b
chr6_-_10728921 0.28 ENSDART00000151484
Sp3b transcription factor
chr17_-_49412313 0.28 ENSDART00000152100
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr17_+_24590177 0.28 ENSDART00000092941
rearranged L-myc fusion
chr3_+_15773991 0.28 ENSDART00000089923
zinc finger protein 652
chr17_-_11151655 0.28 ENSDART00000156383

chr18_+_6857071 0.27 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr14_-_26482096 0.26 ENSDART00000187280
SMAD family member 5
chr18_+_13077800 0.26 ENSDART00000161153
gigaxonin
chr21_-_217589 0.26 ENSDART00000185017

chr5_-_6561376 0.26 ENSDART00000099570
tankyrase 1 binding protein 1
chr5_-_33959868 0.26 ENSDART00000143652
zgc:63972
chr3_+_40255408 0.25 ENSDART00000074746
Smith-Magenis syndrome chromosome region, candidate 8a
chr23_+_14771979 0.25 ENSDART00000137410
exosome component 10
chr15_-_47193564 0.25 ENSDART00000172453
limbic system-associated membrane protein
chr16_-_33001153 0.25 ENSDART00000147941
malic enzyme 1, NADP(+)-dependent, cytosolic
chr22_-_18546649 0.25 ENSDART00000171277
cold inducible RNA binding protein b
chr23_+_2560005 0.25 ENSDART00000186906
gamma-glutamyltransferase 7
chr16_+_52343905 0.24 ENSDART00000131051
interferon lambda receptor 1
chr15_+_38221196 0.24 ENSDART00000122134
ENSDART00000190099
stromal interaction molecule 1a
chr21_-_21515466 0.24 ENSDART00000147593
nectin cell adhesion molecule 3b
chr15_-_37543839 0.23 ENSDART00000148870
lysine (K)-specific methyltransferase 2Bb
chr22_-_16758438 0.23 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr20_+_32756763 0.23 ENSDART00000023006
family with sequence similarity 84, member A
chr7_+_20917966 0.23 ENSDART00000129161
WD repeat containing, antisense to TP53
chr4_-_3064101 0.23 ENSDART00000135701
pleckstrin homology domain containing, family A member 5
chr22_+_22438783 0.23 ENSDART00000147825
kinesin family member 14
chr17_-_25330775 0.23 ENSDART00000154048
zona pellucida protein C
chr14_-_47849216 0.23 ENSDART00000192796
Rap guanine nucleotide exchange factor (GEF) 2
chr21_+_15733880 0.22 ENSDART00000149371
ENSDART00000184111
isocitrate dehydrogenase 3 (NAD+) beta
chr16_+_33163858 0.22 ENSDART00000101943
Ras-related GTP binding Ca
chr5_-_32505109 0.21 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr7_-_19369002 0.21 ENSDART00000165680
netrin 4
chr17_+_50656177 0.20 ENSDART00000127374
DDHD domain containing 1a
chr22_-_14255659 0.20 ENSDART00000167088
si:ch211-246m6.5
chr16_+_26747766 0.20 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr5_-_12031174 0.20 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr22_-_3595439 0.20 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr3_-_45777226 0.19 ENSDART00000192849
H3 histone, family 3B.1
chr17_+_25332711 0.19 ENSDART00000082319
transmembrane protein 54a
chr5_+_30596822 0.18 ENSDART00000188375
histone H4 transcription factor
chr5_+_50913357 0.18 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr21_-_2287589 0.18 ENSDART00000161554
si:ch73-299h12.4
chr7_+_74141297 0.18 ENSDART00000164992
RNA binding protein with multiple splicing
chr3_-_42016693 0.18 ENSDART00000184741
tweety family member 3a
chr3_+_7040363 0.18 ENSDART00000157805

chr5_+_42259002 0.18 ENSDART00000083778
Era-like 12S mitochondrial rRNA chaperone 1
chr10_-_108952 0.18 ENSDART00000127228
tetratricopeptide repeat domain 3
chr25_-_22889519 0.18 ENSDART00000128250
MOB kinase activator 2a
chr1_-_55196103 0.18 ENSDART00000140153
methylthioribose-1-phosphate isomerase 1
chr20_-_33556983 0.17 ENSDART00000168798
rho-associated, coiled-coil containing protein kinase 2b, like
chr8_-_4596662 0.17 ENSDART00000138199
septin 5a
chr20_-_52902693 0.17 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr8_+_247163 0.17 ENSDART00000122378
centrosomal protein 120
chr20_-_33583779 0.17 ENSDART00000097823
rho-associated, coiled-coil containing protein kinase 2b
chr6_-_10728057 0.17 ENSDART00000002247
Sp3b transcription factor
chr14_+_34514336 0.16 ENSDART00000024440
forkhead box I3b
chr7_-_22632518 0.16 ENSDART00000161046
si:dkey-112a7.4
chr17_+_50657509 0.16 ENSDART00000179957
DDHD domain containing 1a
chr18_+_16715864 0.16 ENSDART00000079758
eukaryotic translation initiation factor 4, gamma 2b
chr18_+_5308392 0.16 ENSDART00000179072
deoxyuridine triphosphatase
chr15_-_18574716 0.16 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr3_-_32965848 0.16 ENSDART00000050930
caspase 6, apoptosis-related cysteine peptidase
chr14_+_48862987 0.15 ENSDART00000167810
zgc:154054
chr7_+_38090515 0.15 ENSDART00000131387
CCAAT/enhancer binding protein (C/EBP), gamma
chr2_-_23677422 0.15 ENSDART00000079131
chromodomain protein, Y-like
chr5_-_64355227 0.15 ENSDART00000170787
family with sequence similarity 78, member Aa
chr4_-_74109792 0.15 ENSDART00000174320
zgc:154045
chr8_+_8196087 0.15 ENSDART00000026965
plexin B3
chr24_-_17400472 0.14 ENSDART00000024691
cullin 1b
chr12_+_48784731 0.14 ENSDART00000158348
zinc finger, MIZ-type containing 1b
chr7_-_22632690 0.14 ENSDART00000165245
si:dkey-112a7.4
chr17_-_2596125 0.14 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr5_-_68244564 0.14 ENSDART00000169350

chr25_-_3623847 0.14 ENSDART00000172586
si:ch211-272n13.3
chr6_+_49028874 0.14 ENSDART00000175254
solute carrier family 16 (monocarboxylate transporter), member 1a
chr3_-_1317290 0.13 ENSDART00000047094

chr13_+_2894536 0.13 ENSDART00000183678

chr5_-_38384289 0.13 ENSDART00000135260
misshapen-like kinase 1
chr4_-_77557279 0.13 ENSDART00000180113

chr23_-_27607039 0.13 ENSDART00000183639
PHD finger protein 8
chr9_-_44905867 0.12 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
chr2_+_56012016 0.12 ENSDART00000146160
ENSDART00000188702
lysyl oxidase-like 5b
chr17_+_9308425 0.12 ENSDART00000188283
ENSDART00000183311
neuronal PAS domain protein 3
chr8_+_53452681 0.12 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr15_-_434503 0.12 ENSDART00000122286

chr3_-_11008532 0.12 ENSDART00000165086

chr14_+_21140612 0.12 ENSDART00000168539
zgc:136929
chr24_+_19578935 0.12 ENSDART00000137175
sulfatase 1
chr7_+_42328578 0.12 ENSDART00000149082
phosphorylase kinase, beta
chr22_-_22231720 0.12 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr16_+_5597600 0.12 ENSDART00000017307
zgc:91890
chr9_+_48007081 0.12 ENSDART00000060593
ENSDART00000099835
zgc:92380
chr5_+_31049742 0.11 ENSDART00000173097
zinc finger, ZZ-type with EF hand domain 1
chr23_+_25201077 0.11 ENSDART00000136675
si:dkey-151g10.3
chr2_+_111919 0.11 ENSDART00000149391
FGGY carbohydrate kinase domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of snai2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.6 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 0.8 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 1.3 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.5 GO:0034969 histone arginine methylation(GO:0034969)
0.1 1.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.6 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.3 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.5 GO:0048478 replication fork protection(GO:0048478)
0.1 0.2 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.8 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0033605 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.7 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 1.4 GO:0043296 apical junction complex(GO:0043296)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.7 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi