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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

Z-value: 0.75

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Transcription factors associated with six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

Gene Symbol Gene ID Gene Info
six3b
ENSDARG00000054879 SIX homeobox 3b
six3a
ENSDARG00000058008 SIX homeobox 3a
six7
ENSDARG00000070107 SIX homeobox 7
six3a
ENSDARG00000114971 SIX homeobox 3a
six1a
ENSDARG00000039304 SIX homeobox 1a
six2b
ENSDARG00000054878 SIX homeobox 2b
six2a
ENSDARG00000058004 SIX homeobox 2a
six5
ENSDARG00000068406 SIX homeobox 5
six9
ENSDARG00000068407 SIX homeobox 9
six2a
ENSDARG00000115214 SIX homeobox 2a
six1b
ENSDARG00000026473 SIX homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
six2bdr11_v1_chr12_-_25612170_25612170-0.944.0e-09Click!
six3bdr11_v1_chr12_+_25600685_25600685-0.941.3e-08Click!
six1bdr11_v1_chr20_+_20499869_20499869-0.911.6e-07Click!
six7dr11_v1_chr7_-_7420301_7420301-0.903.7e-07Click!
six9dr11_v1_chr18_-_37241080_37241115-0.864.4e-06Click!
six5dr11_v1_chr18_-_37252036_372520360.813.9e-05Click!
six3adr11_v1_chr13_-_10261383_10261383-0.771.8e-04Click!
six1adr11_v1_chr13_-_31622195_31622195-0.542.2e-02Click!
six2adr11_v1_chr13_+_10232695_102326950.097.3e-01Click!

Activity profile of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b motif

Sorted Z-values of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_42898220 3.87 ENSDART00000099270
CU326366.2

chr18_-_49283058 2.44 ENSDART00000076554
si:zfos-464b6.2
si:zfos-464b6.2
chr11_-_44194132 2.44 ENSDART00000182954
ENSDART00000111271
CABZ01080074.1

chr17_+_16429826 2.28 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr21_-_7940043 2.14 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr10_+_42898103 1.74 ENSDART00000015872
zcchc9
zinc finger, CCHC domain containing 9
chr25_-_21763750 1.58 ENSDART00000089596
tmem168b
transmembrane protein 168b
chr10_+_10972795 1.27 ENSDART00000127331
cdc37l1
cell division cycle 37-like 1
chr17_-_2573021 1.22 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr19_+_34230108 1.10 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr20_+_34502606 1.08 ENSDART00000139739
gorab
golgin, rab6-interacting
chr5_+_37903790 1.07 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr5_+_41477526 1.05 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr11_-_41220794 1.01 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr5_+_36899691 1.00 ENSDART00000132322
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr15_+_41815703 0.92 ENSDART00000059508
pxylp1
2-phosphoxylose phosphatase 1
chr16_+_50755133 0.91 ENSDART00000029283
IGLON5
zgc:110372
chr8_-_26961779 0.90 ENSDART00000099214
slc16a1b
solute carrier family 16 (monocarboxylate transporter), member 1b
chr16_+_26735894 0.82 ENSDART00000191605
ENSDART00000185175
rad54b
RAD54 homolog B (S. cerevisiae)
chr1_-_24255149 0.78 ENSDART00000146960
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr21_-_26028205 0.72 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr7_-_72423666 0.71 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr7_+_56517402 0.70 ENSDART00000073597
dhodh
dihydroorotate dehydrogenase
chr5_+_41477954 0.67 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr20_+_37866861 0.65 ENSDART00000153220
vash2
vasohibin 2
chr5_+_36900157 0.64 ENSDART00000183533
ENSDART00000051184
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr4_-_27398385 0.60 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr22_-_5171362 0.57 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr7_-_29356084 0.52 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr5_-_26247973 0.51 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr16_-_46567344 0.51 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr17_+_13099476 0.51 ENSDART00000012670
pnn
pinin, desmosome associated protein
chr16_-_46567136 0.50 ENSDART00000159180
si:dkey-152b24.7
si:dkey-152b24.7
chr6_-_28222592 0.47 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr7_-_59515569 0.46 ENSDART00000163343
ENSDART00000165457
ENSDART00000163745
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr24_+_30435164 0.45 ENSDART00000193877
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr10_-_32610776 0.45 ENSDART00000017436
mogat2
monoacylglycerol O-acyltransferase 2
chr23_-_27045231 0.42 ENSDART00000187979
zgc:66440
zgc:66440
chr16_+_41060161 0.42 ENSDART00000141130
scap
SREBF chaperone
chr23_-_4019699 0.42 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr23_-_4019928 0.41 ENSDART00000021062
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr2_+_26240631 0.41 ENSDART00000129895
palm1b
paralemmin 1b
chr5_-_54395488 0.40 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr4_-_7811925 0.39 ENSDART00000103070
cdk17
cyclin-dependent kinase 17
chr21_-_21465111 0.39 ENSDART00000141487
nectin3b
nectin cell adhesion molecule 3b
chr25_+_3788074 0.38 ENSDART00000154008
chid1
chitinase domain containing 1
chr1_+_37752171 0.38 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr9_-_13871935 0.38 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr7_-_71486162 0.35 ENSDART00000045253
aco1
aconitase 1, soluble
chr21_+_18405585 0.34 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr12_+_13742778 0.34 ENSDART00000111401
ENSDART00000190552
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr12_+_13742953 0.32 ENSDART00000152257
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr16_+_14201401 0.32 ENSDART00000113679
dap3
death associated protein 3
chr6_-_7686594 0.29 ENSDART00000091836
ENSDART00000151697
ubn2a
ubinuclein 2a
chr9_-_28990649 0.29 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr20_-_45058041 0.27 ENSDART00000124298
klhl29
kelch-like family member 29
chr2_-_38312757 0.25 ENSDART00000167274
ap1g2
adaptor-related protein complex 1, gamma 2 subunit
chr9_+_26086135 0.25 ENSDART00000011910
arglu1a
arginine and glutamate rich 1a
chr24_-_36175365 0.23 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr13_+_33368140 0.23 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr8_+_32722842 0.22 ENSDART00000147594
hmcn2
hemicentin 2
chr22_-_11520405 0.22 ENSDART00000063157
slc26a11
solute carrier family 26 (anion exchanger), member 11
chr24_-_18809433 0.21 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr20_+_22067337 0.20 ENSDART00000152636
clocka
clock circadian regulator a
chr19_-_15434813 0.19 ENSDART00000019843
ftr55
finTRIM family, member 55
chr13_-_40120252 0.18 ENSDART00000157852
crtac1b
cartilage acidic protein 1b
chr10_+_23520952 0.17 ENSDART00000125317
zmp:0000000937
zmp:0000000937
chr15_-_38218320 0.15 ENSDART00000152363
rhoga
ras homolog family member Ga
chr10_+_35468978 0.13 ENSDART00000131984
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr15_+_37546391 0.13 ENSDART00000186625
psenen
presenilin enhancer gamma secretase subunit
chr22_+_2315996 0.13 ENSDART00000132489
znf1175
zinc finger protein 1175
chr17_+_132555 0.13 ENSDART00000158159
zgc:77287
zgc:77287
chr15_-_43270889 0.12 ENSDART00000166805
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr23_+_39481537 0.12 ENSDART00000187222
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr13_+_9678427 0.12 ENSDART00000153907
sema4ga
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga
chr17_-_44776224 0.12 ENSDART00000156195
zdhhc22
zinc finger, DHHC-type containing 22
chr10_+_14488625 0.12 ENSDART00000026383
sigmar1
sigma non-opioid intracellular receptor 1
chr15_+_40792667 0.11 ENSDART00000193186
ENSDART00000184559
fat3a
FAT atypical cadherin 3a
chr7_-_36113098 0.11 ENSDART00000064913
fto
fat mass and obesity associated
chr21_-_2158298 0.11 ENSDART00000182199
gb:ai877918
expressed sequence AI877918
chr5_-_12823876 0.10 ENSDART00000019461
p2rx2
purinergic receptor P2X, ligand-gated ion channel, 2
chr5_+_68112194 0.10 ENSDART00000162468
CABZ01083937.1

chr14_+_22397251 0.09 ENSDART00000185239
ENSDART00000124072
ENSDART00000054977
atp7a
ATPase copper transporting alpha
chr11_-_24016761 0.09 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chia.3
chitinase, acidic.3
chr18_+_33284202 0.09 ENSDART00000132758
v2ra17
vomeronasal 2 receptor, a17
chr1_+_532766 0.09 ENSDART00000179731
ENSDART00000060944
mrpl39
mitochondrial ribosomal protein L39
chr8_-_25566347 0.08 ENSDART00000138289
ENSDART00000078022
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr18_+_5308392 0.08 ENSDART00000179072
DUT
deoxyuridine triphosphatase
chr11_+_24002503 0.07 ENSDART00000164702
chia.2
chitinase, acidic.2
chr20_+_13783040 0.07 ENSDART00000115329
ENSDART00000152497
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr7_+_2244859 0.07 ENSDART00000114242
ENSDART00000064292
si:ch211-285c6.4
si:ch211-285c6.4
chr3_+_1724941 0.07 ENSDART00000193402
BX321875.2

chr13_+_25549425 0.07 ENSDART00000087553
ENSDART00000169199
sec23ip
SEC23 interacting protein
chr8_+_7801060 0.07 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr25_+_19008497 0.06 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr3_-_49815223 0.06 ENSDART00000181208
gcgra
glucagon receptor a
chr5_+_26806141 0.06 ENSDART00000142753
rabl6b
RAB, member RAS oncogene family-like 6b
chr9_-_22076368 0.06 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr3_-_5067585 0.05 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr4_+_14826299 0.05 ENSDART00000067035
shisal1a
shisa like 1a
chr12_-_35095414 0.05 ENSDART00000153229
si:dkey-21e13.3
si:dkey-21e13.3
chr5_+_13326765 0.05 ENSDART00000090851
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr13_-_3324764 0.05 ENSDART00000102748
ENSDART00000114040
ubr2
ubiquitin protein ligase E3 component n-recognin 2
chr15_+_15173611 0.04 ENSDART00000155267
si:ch211-149e23.4
si:ch211-149e23.4
chr14_+_26805388 0.04 ENSDART00000044389
ENSDART00000173126
klhl4
kelch-like family member 4
chr5_-_41841892 0.04 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr24_-_21588914 0.04 ENSDART00000152054
gpr12
G protein-coupled receptor 12
chr21_+_40307476 0.04 ENSDART00000132774
si:ch211-218m3.19
si:ch211-218m3.19
chr15_-_37834433 0.04 ENSDART00000189748
si:dkey-238d18.3
si:dkey-238d18.3
chr1_+_11691722 0.04 ENSDART00000134531
eif3bb
eukaryotic translation initiation factor 3, subunit Bb
chr13_+_25412307 0.03 ENSDART00000175339
calhm1
calcium homeostasis modulator 1
chr13_+_9678262 0.03 ENSDART00000111365
sema4ga
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga
chr10_+_40633990 0.03 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
si:ch211-238p8.31
chr11_+_1602916 0.03 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr15_-_31406093 0.02 ENSDART00000123444
or111-8
odorant receptor, family D, subfamily 111, member 8
chr5_+_40224938 0.02 ENSDART00000142897
si:dkey-193c22.2
si:dkey-193c22.2
chr10_+_9410304 0.02 ENSDART00000080843
ndufa8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr9_+_35017702 0.02 ENSDART00000193640
gabpa
GA binding protein transcription factor, alpha subunit
chr21_-_43094210 0.02 ENSDART00000144747
si:ch73-68b22.2
si:ch73-68b22.2
chr7_-_40657831 0.01 ENSDART00000084153
nom1
nucleolar protein with MIF4G domain 1
chr4_-_27301356 0.01 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr10_+_21718468 0.01 ENSDART00000126622
pcdh1gb9
protocadherin 1 gamma b 9
chr2_+_49631850 0.01 ENSDART00000114274
ENSDART00000114516
si:dkey-53k12.18
si:dkey-53k12.18
chr19_-_22664128 0.01 ENSDART00000136295
eif3eb
eukaryotic translation initiation factor 3, subunit E, b
chr16_+_29630965 0.01 ENSDART00000185820
ENSDART00000192105
ENSDART00000153683
ENSDART00000186713
VPS72
si:ch211-203d17.1
chr18_+_33322515 0.00 ENSDART00000136603
v2ra18
vomeronasal 2 receptor, a18
chr5_-_24112175 0.00 ENSDART00000131595
si:ch211-114c12.5
si:ch211-114c12.5
chr4_+_74396786 0.00 ENSDART00000127501
ENSDART00000174347
zmp:0000001020
zmp:0000001020
chr10_+_23441488 0.00 ENSDART00000100783
si:ch73-122g19.1
si:ch73-122g19.1
chr6_+_41186320 0.00 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2

Network of associatons between targets according to the STRING database.

First level regulatory network of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.9 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.5 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0010039 response to iron ion(GO:0010039)
0.1 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.7 GO:0071712 protein O-linked mannosylation(GO:0035269) ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.3 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.4 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.2 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.1 GO:0042987 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.8 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.3 GO:0006896 Golgi to vacuole transport(GO:0006896)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.7 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 0.7 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.5 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 1.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.8 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 1.3 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.4 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing