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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for scrt1a+scrt1b+scrt2

Z-value: 1.09

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Transcription factors associated with scrt1a+scrt1b+scrt2

Gene Symbol Gene ID Gene Info
scrt1b
ENSDARG00000040214 scratch family zinc finger 1b
scrt2
ENSDARG00000056175 scratch family zinc finger 2
scrt1a
ENSDARG00000100821 scratch family zinc finger 1a
scrt1b
ENSDARG00000110984 scratch family zinc finger 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
scrt1adr11_v1_chr19_+_1184878_11848780.381.2e-01Click!
scrt1bdr11_v1_chr16_-_31188715_311887150.175.0e-01Click!
scrt2dr11_v1_chr8_+_28527776_28527776-0.165.2e-01Click!

Activity profile of scrt1a+scrt1b+scrt2 motif

Sorted Z-values of scrt1a+scrt1b+scrt2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_7636941 2.53 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr6_+_46309795 2.42 ENSDART00000154817
si:dkeyp-67f1.1
si:dkeyp-67f1.1
chr13_-_36844945 2.15 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr16_-_43233509 1.84 ENSDART00000025877
cldn12
claudin 12
chr21_-_30994577 1.80 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr25_+_27937585 1.80 ENSDART00000151994
cadps2
Ca++-dependent secretion activator 2
chr13_+_8840772 1.78 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr5_-_48664522 1.77 ENSDART00000083229
mblac2
metallo-beta-lactamase domain containing 2
chr25_+_27937789 1.76 ENSDART00000023890
cadps2
Ca++-dependent secretion activator 2
chr17_-_30521043 1.66 ENSDART00000087111
itsn2b
intersectin 2b
chr2_+_9560740 1.63 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr24_-_34335265 1.62 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr15_+_25489406 1.61 ENSDART00000162482
zgc:152863
zgc:152863
chr21_-_4849029 1.56 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr21_-_9562272 1.51 ENSDART00000162225
ENSDART00000163874
ENSDART00000168173
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr2_-_10564019 1.47 ENSDART00000132167
ccdc18
coiled-coil domain containing 18
chr14_+_35424539 1.45 ENSDART00000171809
ENSDART00000162185
sytl4
synaptotagmin-like 4
chr10_-_41352502 1.45 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr8_+_11425048 1.45 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr2_-_10563576 1.44 ENSDART00000185818
ENSDART00000190887
ccdc18
coiled-coil domain containing 18
chr5_+_37649206 1.36 ENSDART00000149151
ENSDART00000097723
sptbn2
spectrin, beta, non-erythrocytic 2
chr17_+_23462972 1.28 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr16_+_21918503 1.28 ENSDART00000167919
znf687a
zinc finger protein 687a
chr2_+_1988036 1.27 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr9_-_28939181 1.22 ENSDART00000101276
ENSDART00000135334
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr3_+_42923275 1.19 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr8_+_10823069 1.18 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr7_+_31051603 1.18 ENSDART00000108721
tjp1a
tight junction protein 1a
chr23_+_4741543 1.16 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr24_-_21903588 1.15 ENSDART00000180991
spata13
spermatogenesis associated 13
chr8_-_30424182 1.14 ENSDART00000099021
dock8
dedicator of cytokinesis 8
chr24_-_21903360 1.11 ENSDART00000091252
spata13
spermatogenesis associated 13
chr23_-_32157865 1.10 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr3_+_53240562 1.10 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr12_-_3705862 1.10 ENSDART00000193864
ENSDART00000185857
CABZ01069040.1

chr10_+_31809226 1.08 ENSDART00000087898
foxo1b
forkhead box O1 b
chr7_+_52712807 1.08 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
znf280d
zinc finger protein 280D
chr22_+_26600834 1.05 ENSDART00000157411
adcy9
adenylate cyclase 9
chr23_-_18130264 1.00 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr22_+_28803739 0.98 ENSDART00000129476
ENSDART00000189726
tp53bp2b
tumor protein p53 binding protein, 2b
chr2_+_25378457 0.97 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr3_-_56030117 0.96 ENSDART00000113030
ENSDART00000157764
cep112
centrosomal protein 112
chr11_+_39928828 0.95 ENSDART00000137516
ENSDART00000134082
vamp3
vesicle-associated membrane protein 3 (cellubrevin)
chr2_-_32247341 0.94 ENSDART00000146452
fam49ba
family with sequence similarity 49, member Ba
chr5_+_44806374 0.94 ENSDART00000184237
ctsla
cathepsin La
chr11_+_14321113 0.93 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr8_-_1838315 0.87 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr8_+_46939391 0.80 ENSDART00000146631
espn
espin
chr14_-_46897067 0.80 ENSDART00000058789
qdpra
quinoid dihydropteridine reductase a
chr2_+_37838259 0.79 ENSDART00000136796
parp2
poly (ADP-ribose) polymerase 2
chr24_+_24086491 0.79 ENSDART00000145092
lipib
lipase, member Ib
chr14_-_48033073 0.79 ENSDART00000193115
ENSDART00000169300
ENSDART00000188036
ENSDART00000183432
ENSDART00000180973
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_6115688 0.74 ENSDART00000081663
prdx1
peroxiredoxin 1
chr4_-_21466480 0.70 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr7_-_71456117 0.70 ENSDART00000042492
sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr12_+_33484458 0.70 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr17_+_34186632 0.69 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr15_+_20529197 0.67 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr10_-_13396720 0.66 ENSDART00000030976
il11ra
interleukin 11 receptor, alpha
chr7_+_24889783 0.66 ENSDART00000005329
ENSDART00000159955
mark2b
MAP/microtubule affinity-regulating kinase 2b
chr12_-_20409794 0.66 ENSDART00000077936
lcmt1
leucine carboxyl methyltransferase 1
chr23_-_26784736 0.66 ENSDART00000024064
ENSDART00000131615
galnt6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr15_+_24746444 0.65 ENSDART00000032306
ywhae1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr2_+_50477779 0.65 ENSDART00000122716
CABZ01067973.1

chr2_-_6115389 0.64 ENSDART00000134921
prdx1
peroxiredoxin 1
chr16_-_9869056 0.64 ENSDART00000149312
ncalda
neurocalcin delta a
chr3_-_61494840 0.59 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr8_-_9684872 0.58 ENSDART00000132158
ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr25_-_29074064 0.56 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr12_+_13742953 0.53 ENSDART00000152257
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr7_-_26497947 0.53 ENSDART00000058910
sox19b
SRY (sex determining region Y)-box 19b
chr25_-_893464 0.49 ENSDART00000159321
znf609a
zinc finger protein 609a
chr7_-_52498175 0.47 ENSDART00000129769
cgnl1
cingulin-like 1
chr15_+_17848590 0.47 ENSDART00000168940
zgc:113279
zgc:113279
chr18_+_9493720 0.42 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_+_46939566 0.40 ENSDART00000139422
espn
espin
chr16_-_32975951 0.39 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr18_+_41313999 0.39 ENSDART00000048985
veph1
ventricular zone expressed PH domain-containing 1
chr17_-_12758171 0.39 ENSDART00000131564
brms1la
breast cancer metastasis-suppressor 1-like a
chr19_+_10558994 0.38 ENSDART00000148353
usf2
upstream transcription factor 2, c-fos interacting
chr4_+_6736746 0.36 ENSDART00000184175
tmem168a
transmembrane protein 168a
chr19_-_45650994 0.35 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr6_-_52675630 0.35 ENSDART00000083830
sdc4
syndecan 4
chr25_-_16666886 0.33 ENSDART00000155764
slc25a18
solute carrier family 25 (glutamate carrier), member 18
chr13_-_8446341 0.32 ENSDART00000080382
epas1b
endothelial PAS domain protein 1b
chr17_-_2690083 0.27 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr8_-_24970790 0.25 ENSDART00000141267
si:ch211-199o1.2
si:ch211-199o1.2
chr3_-_16039619 0.24 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr7_-_29292206 0.22 ENSDART00000086753
dapk2a
death-associated protein kinase 2a
chr20_+_22220988 0.19 ENSDART00000049204
kdr
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr22_+_26804197 0.19 ENSDART00000135688
si:dkey-44g23.2
si:dkey-44g23.2
chr17_+_47090497 0.19 ENSDART00000169038
ENSDART00000159292
zgc:103755
zgc:103755
chr12_+_20678187 0.19 ENSDART00000146762
st6galnac1.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 1
chr5_-_29587351 0.18 ENSDART00000136446
ENSDART00000051434
entpd2a.1
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr7_+_61184551 0.17 ENSDART00000190788
zgc:194930
zgc:194930
chr23_-_43713757 0.14 ENSDART00000192175
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr9_-_21970067 0.14 ENSDART00000009920
lmo7a
LIM domain 7a
chr23_+_38245610 0.13 ENSDART00000191386
znf217
zinc finger protein 217
chr4_+_31085014 0.13 ENSDART00000172541
si:dkey-47k16.4
si:dkey-47k16.4
chr17_-_6508406 0.13 ENSDART00000002778
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr13_+_13578552 0.13 ENSDART00000101673
foxi2
forkhead box I2
chr22_-_6144428 0.13 ENSDART00000106118
si:dkey-19a16.4
si:dkey-19a16.4
chr11_+_21587950 0.12 ENSDART00000162251
FAM72B
zgc:101564
chr18_-_43880020 0.10 ENSDART00000185638
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr21_+_29227224 0.08 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr10_-_19523752 0.08 ENSDART00000160057
si:ch211-127i16.2
si:ch211-127i16.2
chr7_-_18700364 0.07 ENSDART00000112359
si:ch211-119e14.9
si:ch211-119e14.9
chr19_-_3303995 0.05 ENSDART00000105150
si:ch211-133n4.9
si:ch211-133n4.9
chr22_-_6362442 0.05 ENSDART00000149907
ENSDART00000106104
zgc:113298
zgc:113298
chr7_-_72261721 0.05 ENSDART00000172229
RASGRP2
RAS guanyl releasing protein 2
chr10_+_17776981 0.04 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr6_+_27361978 0.03 ENSDART00000065238
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr23_+_37579107 0.02 ENSDART00000169376
plekhg5b
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr12_+_5209822 0.02 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr21_+_41697552 0.02 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr10_-_1827225 0.02 ENSDART00000058627
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr20_+_34511678 0.01 ENSDART00000061588
prrx1b
paired related homeobox 1b
chr14_+_29941266 0.01 ENSDART00000112757
fam149a
family with sequence similarity 149 member A
chr9_+_45789887 0.00 ENSDART00000135202
si:dkey-34f9.3
si:dkey-34f9.3

Network of associatons between targets according to the STRING database.

First level regulatory network of scrt1a+scrt1b+scrt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.4 2.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 3.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 1.9 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.4 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.1 1.4 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 2.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.8 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.7 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.6 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.7 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:0051693 actin filament capping(GO:0051693)
0.0 0.7 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 1.0 GO:0009190 cyclic nucleotide biosynthetic process(GO:0009190)
0.0 0.3 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 2.9 GO:0006887 exocytosis(GO:0006887)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0008091 spectrin(GO:0008091)
0.2 2.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 7.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.8 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 1.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.5 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 5.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 2.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.3 GO:0050839 cell adhesion molecule binding(GO:0050839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins