Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for runx2a+runx2b

Z-value: 0.83

Motif logo

Transcription factors associated with runx2a+runx2b

Gene Symbol Gene ID Gene Info
ENSDARG00000040261 RUNX family transcription factor 2a
ENSDARG00000059233 RUNX family transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx2adr11_v1_chr17_+_5351922_5351922-0.322.0e-01Click!
runx2bdr11_v1_chr20_-_44055095_440551230.253.3e-01Click!

Activity profile of runx2a+runx2b motif

Sorted Z-values of runx2a+runx2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_24488652 2.52 ENSDART00000052067
insulin-like 3 (Leydig cell)
chr24_+_31361407 1.79 ENSDART00000162668
cAMP responsive element modulator b
chr24_+_17269849 1.75 ENSDART00000017605
sperm associated antigen 6
chr17_+_21295132 1.74 ENSDART00000103845
enolase family member 4
chr16_+_28727383 1.56 ENSDART00000149753
DC-STAMP domain containing 2
chr17_+_26815021 1.48 ENSDART00000086885
acetylserotonin O-methyltransferase 2
chr5_+_13359146 1.38 ENSDART00000179839
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr22_-_36934040 1.36 ENSDART00000151666
Pim proto-oncogene, serine/threonine kinase, related 206
chr24_+_17270129 1.35 ENSDART00000186729
sperm associated antigen 6
chr18_+_5543677 1.26 ENSDART00000146161
ENSDART00000136189
nicotinamide nucleotide transhydrogenase 2
chr7_-_1504382 1.25 ENSDART00000172770
si:zfos-405g10.4
chr8_-_41273461 1.19 ENSDART00000190598
ring finger protein 10
chr25_-_32449235 1.17 ENSDART00000115343
ATPase phospholipid transporting 8B4
chr7_+_23515966 1.17 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr12_-_25612170 1.17 ENSDART00000077155
SIX homeobox 2b
chr16_-_13613475 1.11 ENSDART00000139102
D site albumin promoter binding protein b
chr14_+_33049579 1.10 ENSDART00000113470
testis expressed 11
chr20_-_32658305 1.09 ENSDART00000140622
ENSDART00000152909
si:dkey-6f10.3
chr22_+_36914636 1.09 ENSDART00000150948
Pim proto-oncogene, serine/threonine kinase, related 205
chr7_-_24364536 1.09 ENSDART00000064789
thioredoxin
chr14_+_3944826 1.09 ENSDART00000170167
LRP2 binding protein
chr13_-_33683889 1.04 ENSDART00000136820
ENSDART00000065435
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr12_-_23129453 1.04 ENSDART00000077453
armadillo repeat containing 4
chr12_+_26467847 1.02 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr8_-_13046089 0.98 ENSDART00000137784
si:dkey-208b23.5
chr1_-_9109699 0.97 ENSDART00000147833
vascular associated protein
chr23_+_8797143 0.97 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr25_+_16646113 0.97 ENSDART00000110426
cat eye syndrome chromosome region, candidate 2
chr8_-_21372446 0.96 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr24_-_27419198 0.95 ENSDART00000141124
chemokine (C-C motif) ligand 34b, duplicate 4
chr9_+_7732714 0.94 ENSDART00000145853
si:ch1073-349o24.2
chr2_+_24786765 0.94 ENSDART00000141030
phosphodiesterase 4C, cAMP-specific a
chr2_+_22694382 0.93 ENSDART00000139196
kinesin family member 1Ab
chr3_+_15809098 0.90 ENSDART00000183023
phosphatase, orphan 1
chr10_-_20453995 0.89 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
chr13_-_6081803 0.88 ENSDART00000099224
deltaD
chr5_-_21888368 0.88 ENSDART00000020725
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr7_-_20758825 0.88 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chromodomain helicase DNA binding protein 3
chr17_-_10025234 0.87 ENSDART00000008355
cofilin 2 (muscle)
chr7_-_16597130 0.87 ENSDART00000144118
E2F transcription factor 8
chr16_+_31853919 0.86 ENSDART00000133886
atrophin 1
chr12_-_23128746 0.83 ENSDART00000170018
armadillo repeat containing 4
chr7_+_39706004 0.82 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr15_+_19838458 0.81 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr7_+_46368520 0.80 ENSDART00000192821
zinc finger protein 536
chr18_+_25752592 0.79 ENSDART00000111767
si:ch211-39k3.2
chr3_+_26734162 0.79 ENSDART00000114552
si:dkey-202l16.5
chr24_-_33693070 0.77 ENSDART00000137483
si:dkeyp-87a6.2
chr25_-_14637660 0.77 ENSDART00000143666
neuron navigator 2b
chr19_-_18152407 0.76 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr9_-_34885902 0.76 ENSDART00000137504
P2Y receptor family member 8
chr1_+_50538839 0.76 ENSDART00000020412
polycystic kidney disease 2
chr17_-_33714636 0.76 ENSDART00000188500
si:dkey-84k17.3
chr21_-_21790372 0.76 ENSDART00000151094
X-ray radiation resistance associated 1
chr20_+_33610271 0.75 ENSDART00000187186

chr11_-_22605981 0.75 ENSDART00000186923
myogenin
chr12_-_36521767 0.75 ENSDART00000110290
unc-13 homolog D (C. elegans)
chr19_+_19786117 0.75 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr3_+_37197686 0.73 ENSDART00000151144
formin-like 1a
chr14_-_21123551 0.73 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr23_-_29003864 0.73 ENSDART00000148257
castor zinc finger 1
chr17_-_4395373 0.72 ENSDART00000015923
kelch-like family member 10a
chr10_+_10351685 0.72 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr5_-_32445835 0.71 ENSDART00000170919
neuronal calcium sensor 1a
chr7_-_16596938 0.71 ENSDART00000134548
E2F transcription factor 8
chr4_+_41602 0.70 ENSDART00000159640
putative homeodomain transcription factor 2
chr4_-_8152746 0.70 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr24_+_23730061 0.70 ENSDART00000080343
protein phosphatase 1, regulatory subunit 42
chr25_+_25438165 0.69 ENSDART00000161369
si:ch211-103e16.5
chr10_+_31344227 0.69 ENSDART00000184470

chr2_+_31600661 0.68 ENSDART00000139039
si:ch211-106h4.4
chr24_+_26658132 0.67 ENSDART00000183081

chr5_+_28313824 0.66 ENSDART00000135878
si:dkeyp-86b9.1
chr2_+_24722771 0.66 ENSDART00000147207
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr15_-_23376541 0.66 ENSDART00000078570
C1q and TNF related 5
chr11_-_8208464 0.65 ENSDART00000161283
Pim proto-oncogene, serine/threonine kinase, related 203
chr16_-_54455573 0.65 ENSDART00000075275
pyruvate kinase L/R
chr7_-_51102479 0.64 ENSDART00000174023
collagen, type IV, alpha 6
chr20_+_33679500 0.64 ENSDART00000145242
si:ch211-199m3.1
chr14_-_14566417 0.63 ENSDART00000159056
si:dkey-27i16.2
chr20_+_18225329 0.63 ENSDART00000144172
potassium channel tetramerization domain containing 1
chr3_-_52674089 0.62 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
chr14_-_21123325 0.62 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr20_+_33560419 0.61 ENSDART00000161563
ENSDART00000189650
si:dkey-65b13.8
chr9_-_42696408 0.61 ENSDART00000144744
collagen, type V, alpha 2a
chr5_-_63425428 0.60 ENSDART00000163246
centriolin
chr20_+_52458765 0.60 ENSDART00000057980
tissue specific transplantation antigen P35B
chr16_-_35585374 0.59 ENSDART00000180208
Scm polycomb group protein homolog 1
chr7_-_41403022 0.59 ENSDART00000174285

chr2_-_26563978 0.58 ENSDART00000150016
GLIS family zinc finger 1a
chr15_+_37412883 0.58 ENSDART00000156474
zinc finger and BTB domain containing 32
chr4_-_9533345 0.58 ENSDART00000128501
si:ch73-139j3.4
chr1_+_2101541 0.57 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
muscleblind-like splicing regulator 2
chr1_-_46505310 0.57 ENSDART00000178072
si:busm1-105l16.2
chr8_-_41273768 0.56 ENSDART00000108518
ring finger protein 10
chr4_-_26108053 0.56 ENSDART00000066951
si:ch211-244b2.4
chr2_-_16159491 0.56 ENSDART00000110059
vav 3 guanine nucleotide exchange factor b
chr4_-_8093753 0.56 ENSDART00000133434
WNK lysine deficient protein kinase 1b
chr20_-_1174266 0.56 ENSDART00000023304
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr25_+_20119466 0.56 ENSDART00000104304
2,3-bisphosphoglycerate mutase
chr13_+_27316934 0.56 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr7_+_25858380 0.55 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr22_-_30973791 0.55 ENSDART00000104728
ssu-2 homolog, tandem duplicate 2
chr9_-_46842179 0.55 ENSDART00000054137
insulin-like growth factor binding protein 5b
chr10_+_2742499 0.53 ENSDART00000122847
G protein-coupled receptor kinase 5
chr21_+_25198637 0.52 ENSDART00000164972
si:dkey-183i3.6
chr12_-_26851726 0.52 ENSDART00000047724
zinc finger E-box binding homeobox 1b
chr23_-_36724575 0.51 ENSDART00000159560
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_-_8795081 0.51 ENSDART00000106671
transforming growth factor, beta 2, like
chr22_-_36996856 0.51 ENSDART00000165923
si:dkey-211e20.10
chr19_-_18152942 0.51 ENSDART00000190182
nuclear factor, erythroid 2-like 3
chr18_+_34861568 0.51 ENSDART00000192825

chr19_+_5604241 0.50 ENSDART00000011025
WAS/WASL interacting protein family, member 2b
chr11_+_24815667 0.50 ENSDART00000141730
RAB interacting factor
chr1_+_1689775 0.50 ENSDART00000048828
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4
chr11_+_13630107 0.50 ENSDART00000172220
si:ch211-1a19.3
chr2_+_48288461 0.49 ENSDART00000141495
hes family bHLH transcription factor 6
chr22_-_17729778 0.49 ENSDART00000192132
si:ch73-63e15.2
chr19_+_40856534 0.48 ENSDART00000051950
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr1_+_34203817 0.48 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr25_-_7925269 0.47 ENSDART00000014274
glucuronic acid epimerase a
chr20_+_35086242 0.47 ENSDART00000114262
CDC42 binding protein kinase alpha (DMPK-like) b
chr7_+_19903924 0.47 ENSDART00000159112
si:ch211-285j22.3
chr9_-_40765868 0.47 ENSDART00000138634
ATP-binding cassette, sub-family A (ABC1), member 12
chr23_-_40796992 0.47 ENSDART00000145116
si:dkey-194e6.2
chr4_+_11375894 0.47 ENSDART00000190471
ENSDART00000143963
piccolo presynaptic cytomatrix protein a
chr7_-_40993456 0.47 ENSDART00000031700
engrailed homeobox 2a
chr10_-_36721726 0.46 ENSDART00000122132
Pim proto-oncogene, serine/threonine kinase, related 137
chr13_-_4333181 0.46 ENSDART00000122406
zinc finger protein 318
chr25_-_7925019 0.46 ENSDART00000183309
glucuronic acid epimerase a
chr6_+_46431848 0.46 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr16_+_50006145 0.46 ENSDART00000049375
ubiquitin-conjugating enzyme E2E 2
chr7_-_24995631 0.45 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr20_+_35445462 0.45 ENSDART00000124497
tudor domain containing 6
chr24_-_21923930 0.45 ENSDART00000131944
transgelin 3b
chr11_-_2478374 0.45 ENSDART00000173205
si:ch73-267c23.10
chr17_-_8899323 0.45 ENSDART00000081590
NK-lysin tandem duplicate 1
chr25_-_3470910 0.44 ENSDART00000029067
ENSDART00000186737
HMG-box transcription factor 1
chr11_+_8129536 0.44 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr21_-_45073 0.44 ENSDART00000185997
betaine-homocysteine methyltransferase
chr9_+_38457806 0.43 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr4_-_52504961 0.43 ENSDART00000163123
si:dkey-78o7.3
chr16_+_21330634 0.43 ENSDART00000191285
ENSDART00000183267
oxysterol binding protein-like 3b
chr6_-_12314475 0.43 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
chr6_-_16394528 0.42 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr19_-_10656667 0.42 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
oleoyl-ACP hydrolase
chr16_-_15263099 0.42 ENSDART00000125691
syntrophin, basic 1
chr21_+_11923701 0.42 ENSDART00000109292
ubiquitin associated protein 2a
chr2_+_14992879 0.42 ENSDART00000137546
Pim proto-oncogene, serine/threonine kinase, related 55
chr25_-_35996141 0.42 ENSDART00000149074
spalt-like transcription factor 1b
chr5_+_62374092 0.42 ENSDART00000082965

chr19_+_25504645 0.41 ENSDART00000143292
collagen, type XXVIII, alpha 1a
chr19_-_7144548 0.41 ENSDART00000147177
ENSDART00000134850
proteasome subunit beta 8A
proteasome subunit beta 13a
chr7_-_18656069 0.40 ENSDART00000021559
coronin, actin binding protein, 1B
chr9_+_38458193 0.40 ENSDART00000008053
minichromosome maintenance complex component 3 associated protein
chr3_-_22212764 0.40 ENSDART00000155490
microtubule-associated protein tau b
chr11_+_18216404 0.39 ENSDART00000086437
transmembrane and coiled-coil domain family 1b
chr6_-_39764995 0.39 ENSDART00000085277
phosphofructokinase, muscle b
chr22_+_30839702 0.38 ENSDART00000139849
ENSDART00000135775
si:dkey-49n23.3
chr2_-_32768951 0.38 ENSDART00000004712
beaded filament structural protein 2, phakinin
chr1_-_56213723 0.38 ENSDART00000142505
ENSDART00000137237
si:dkey-76b14.2
chr5_+_65991152 0.38 ENSDART00000097756
lipocalin 15
chr8_-_17067364 0.38 ENSDART00000132687
RAB3C, member RAS oncogene family
chr17_+_23770848 0.38 ENSDART00000079646
potassium channel, subfamily K, member 18
chr5_+_24059598 0.38 ENSDART00000051547
GABA(A) receptor-associated protein a
chr22_-_34937455 0.38 ENSDART00000169217
ENSDART00000188330
ENSDART00000165142
slit homolog 1b (Drosophila)
chr17_-_23446760 0.38 ENSDART00000104715
polycomb group ring finger 5a
chr18_+_31073265 0.38 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr1_-_47071979 0.38 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr3_+_31621774 0.37 ENSDART00000076636
frizzled class receptor 2
chr21_+_33503835 0.37 ENSDART00000125658
clathrin interactor 1b
chr2_+_24304854 0.37 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr6_+_45918981 0.37 ENSDART00000149642
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_+_9289802 0.37 ENSDART00000188650
kalirin RhoGEF kinase b
chr2_-_54054225 0.37 ENSDART00000167239

chr7_+_65876335 0.37 ENSDART00000150143
TEA domain family member 1b
chr4_+_20255160 0.37 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr8_+_21353878 0.36 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr5_-_39474235 0.36 ENSDART00000171557
anthrax toxin receptor 2a
chr2_+_40181633 0.36 ENSDART00000185494

chr5_+_26913120 0.36 ENSDART00000126609
T-box 3b
chr3_-_1204341 0.36 ENSDART00000089646
family with sequence similarity 234, member B
chr4_-_15420452 0.36 ENSDART00000016230
plexin A4
chr1_+_10318089 0.36 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr1_-_10821584 0.35 ENSDART00000167452
ENSDART00000162137
cytokine receptor family member B15
chr16_-_22863348 0.35 ENSDART00000147609
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_26107841 0.35 ENSDART00000172012
si:ch211-244b2.4
chr4_+_76735113 0.35 ENSDART00000075602
membrane-spanning 4-domains, subfamily A, member 17A.6
chr25_+_14109626 0.35 ENSDART00000109883
actin, alpha, cardiac muscle 1c
chr3_+_60044780 0.35 ENSDART00000080437
zgc:113030
chr24_-_31843173 0.35 ENSDART00000185782
STEAP family member 2, metalloreductase
chr12_+_28856151 0.35 ENSDART00000152969
nuclear factor, erythroid 2-like 1b
chr7_+_8324506 0.34 ENSDART00000168110
si:dkey-185m8.2
chr10_-_5016997 0.34 ENSDART00000101414
heterogeneous nuclear ribonucleoprotein D
chr19_+_1688727 0.34 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr7_-_33248773 0.34 ENSDART00000052389
integrin, alpha 11a
chr4_+_77973876 0.34 ENSDART00000057423
telomeric repeat binding factor a
chr17_+_6217704 0.34 ENSDART00000129100

chr2_-_16159203 0.34 ENSDART00000153480
vav 3 guanine nucleotide exchange factor b
chr23_-_16682186 0.34 ENSDART00000020810
syndecan binding protein (syntenin) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of runx2a+runx2b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0030186 melatonin metabolic process(GO:0030186)
0.4 1.6 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.3 GO:0006740 NADPH regeneration(GO:0006740)
0.3 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 0.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 1.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 1.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 1.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.9 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.8 GO:0021885 forebrain cell migration(GO:0021885)
0.1 0.1 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.1 0.9 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.6 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.1 0.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.3 GO:0048389 intermediate mesoderm development(GO:0048389)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 0.3 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 2.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 3.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.8 GO:0030719 P granule organization(GO:0030719)
0.1 0.6 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.2 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.6 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0021767 mammillary body development(GO:0021767)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.8 GO:0010165 response to X-ray(GO:0010165)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.4 GO:0019320 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) hexose catabolic process(GO:0019320) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 2.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0003151 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.3 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.7 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 1.0 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320) messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0033212 iron assimilation(GO:0033212)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.5 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 3.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.6 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.1 GO:0000801 central element(GO:0000801)
0.2 0.8 GO:0070390 transcription export complex 2(GO:0070390)
0.2 1.8 GO:0031010 ISWI-type complex(GO:0031010)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.5 GO:0033391 chromatoid body(GO:0033391)
0.1 1.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.6 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.6 GO:0016234 inclusion body(GO:0016234)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.2 GO:0010369 chromocenter(GO:0010369)
0.1 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.0 GO:0044447 axoneme part(GO:0044447)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0042641 actomyosin(GO:0042641)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.9 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 1.3 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 1.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.2 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 0.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules