Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for raraa+rarab

Z-value: 0.78

Motif logo

logo of

Transcription factors associated with raraa+rarab

Gene Symbol Gene ID Gene Info
rarab
ENSDARG00000034893 retinoic acid receptor, alpha b
raraa
ENSDARG00000056783 retinoic acid receptor, alpha a
rarab
ENSDARG00000111757 retinoic acid receptor, alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rarabdr11_v1_chr3_-_33175583_33175583-0.997.8e-14Click!
raraadr11_v1_chr12_+_10952794_10952794-0.815.2e-05Click!

Activity profile of raraa+rarab motif

Sorted Z-values of raraa+rarab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_13471916 2.07 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr8_-_13428740 1.94 ENSDART00000131826
CR354547.3

chr18_+_19842569 1.91 ENSDART00000147470
iqch
IQ motif containing H
chr18_+_1145571 1.90 ENSDART00000135055
rec114
REC114 meiotic recombination protein
chr14_-_36862745 1.64 ENSDART00000109293
rnf130
ring finger protein 130
chr8_-_13442871 1.52 ENSDART00000144887
pimr106
Pim proto-oncogene, serine/threonine kinase, related 106
chr8_-_13419049 1.50 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr4_-_191736 1.49 ENSDART00000169187
ENSDART00000192054
ptpro
protein tyrosine phosphatase, receptor type, O
chr21_+_28445052 1.48 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr22_-_31788170 1.44 ENSDART00000170925
pimr207
Pim proto-oncogene, serine/threonine kinase, related 207
chr8_-_13486258 1.35 ENSDART00000137459
pimr104
Pim proto-oncogene, serine/threonine kinase, related 104
chr17_+_46739693 1.27 ENSDART00000097810
pimr22
Pim proto-oncogene, serine/threonine kinase, related 22
chr5_-_3885727 1.26 ENSDART00000143250
mlxipl
MLX interacting protein like
chr8_-_13454281 1.26 ENSDART00000141959
CR354547.2

chr17_+_53311618 1.04 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr22_+_38173960 0.94 ENSDART00000010537
cp
ceruloplasmin
chr24_+_42149453 0.89 ENSDART00000128766
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr21_-_32284532 0.82 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr24_+_21973929 0.82 ENSDART00000042495
sat1b
spermidine/spermine N1-acetyltransferase 1b
chr8_-_28342313 0.81 ENSDART00000005583
kdm5bb
lysine (K)-specific demethylase 5Bb
chr2_+_52847049 0.78 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr23_+_25822742 0.77 ENSDART00000184436
r3hdml
R3H domain containing-like
chr11_+_1608348 0.74 ENSDART00000162438
si:dkey-40c23.3
si:dkey-40c23.3
chr17_+_14886828 0.74 ENSDART00000010507
ENSDART00000131052
ptger2a
prostaglandin E receptor 2a (subtype EP2)
chr22_-_834106 0.72 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr23_+_25305431 0.68 ENSDART00000143291
RPL41
si:dkey-151g10.6
chr18_-_36066087 0.66 ENSDART00000059352
ENSDART00000145177
exosc5
exosome component 5
chr5_+_64856666 0.65 ENSDART00000050863
zgc:101858
zgc:101858
chr22_+_30009926 0.64 ENSDART00000142529
si:dkey-286j15.1
si:dkey-286j15.1
chr12_+_2677303 0.62 ENSDART00000093113
antxr1c
anthrax toxin receptor 1c
chr18_+_3338228 0.62 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr24_+_42149296 0.61 ENSDART00000154231
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr17_+_53311243 0.58 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
asb2b
ankyrin repeat and SOCS box containing 2b
chr13_+_24834199 0.57 ENSDART00000101274
zgc:153981
zgc:153981
chr6_-_8277221 0.51 ENSDART00000053869
slc44a2
solute carrier family 44 (choline transporter), member 2
chr1_+_59154521 0.47 ENSDART00000130089
ENSDART00000152456
soul5l
heme-binding protein soul5, like
chr14_+_94946 0.44 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr2_+_56213694 0.44 ENSDART00000162582
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr19_+_5291935 0.37 ENSDART00000141237
si:dkeyp-113d7.10
si:dkeyp-113d7.10
chr2_+_3696038 0.33 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr18_+_10820430 0.31 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr16_+_7242610 0.31 ENSDART00000081477
sri
sorcin
chr14_-_51855047 0.30 ENSDART00000088912
cplx1
complexin 1
chr23_-_3703569 0.27 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr24_+_37723362 0.26 ENSDART00000136836
rab11fip3
RAB11 family interacting protein 3 (class II)
chr17_+_33340675 0.26 ENSDART00000184396
ENSDART00000077553
xdh
xanthine dehydrogenase
chr11_+_25111846 0.26 ENSDART00000128705
ENSDART00000190058
ndrg3a
ndrg family member 3a
chr3_+_5297493 0.25 ENSDART00000138596
si:ch211-150d5.3
si:ch211-150d5.3
chr19_+_19762183 0.22 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr22_+_20208185 0.21 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr18_+_8340886 0.20 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr14_-_2001386 0.18 ENSDART00000170346
ENSDART00000163975
pcdh2g5
protocadherin 2 gamma 5
chr25_-_3132060 0.18 ENSDART00000014363
epx
eosinophil peroxidase
chr2_+_58841181 0.14 ENSDART00000164102
cirbpa
cold inducible RNA binding protein a
chr1_+_59538755 0.12 ENSDART00000166354
sp6
Sp6 transcription factor
chr17_+_14711765 0.10 ENSDART00000012889
cx28.6
connexin 28.6
chr22_+_21324398 0.10 ENSDART00000168509
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr3_+_57268363 0.10 ENSDART00000180725
TMEM235 (1 of many)
transmembrane protein 235
chr22_-_9900378 0.10 ENSDART00000193906
znf991
zinc finger protein 991
chr4_+_1530287 0.09 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr10_-_41450367 0.08 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr14_+_41518257 0.07 ENSDART00000050037
chrnb3b
cholinergic receptor, nicotinic, beta 3b (neuronal)
chr14_+_94603 0.06 ENSDART00000162480
mcm7
minichromosome maintenance complex component 7
chr25_+_1549838 0.06 ENSDART00000115001
avpr1aa
arginine vasopressin receptor 1Aa
chr24_+_42117231 0.04 ENSDART00000067734
snx16
sorting nexin 16

Network of associatons between targets according to the STRING database.

First level regulatory network of raraa+rarab

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.8 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.7 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.5 GO:0015871 choline transport(GO:0015871)
0.1 0.7 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.6 GO:1901998 toxin transport(GO:1901998)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.5 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 9.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.8 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism