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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for pou2f2a
Z-value: 0.87
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Transcription factors associated with pou2f2a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pou2f2a | dr11_v1_chr19_-_6239248_6239248 | -0.99 | 2.6e-14 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr25_+_22320738 Show fit | 4.80 |
ENSDART00000073566
|
cytochrome P450, family 11, subfamily A, polypeptide 1 |
|
| chr1_-_51038885 Show fit | 3.81 |
ENSDART00000035150
|
spastin |
|
| chr5_-_65662996 Show fit | 3.38 |
ENSDART00000147707
|
calmodulin regulated spectrin-associated protein 1b |
|
| chr17_-_4245311 Show fit | 2.80 |
ENSDART00000055379
|
growth differentiation factor 3 |
|
| chr23_+_7692042 Show fit | 2.77 |
ENSDART00000018512
|
protein O-fucosyltransferase 1 |
|
| chr17_-_4245902 Show fit | 2.32 |
ENSDART00000151851
|
growth differentiation factor 3 |
|
| chr4_-_9780931 Show fit | 2.16 |
ENSDART00000134280
ENSDART00000150664 ENSDART00000150304 ENSDART00000080744 |
SVOP-like |
|
| chr22_+_980290 Show fit | 2.04 |
ENSDART00000065377
|
differentially expressed in FDCP 6b homolog (mouse) |
|
| chr1_-_45320126 Show fit | 1.93 |
ENSDART00000133572
|
si:ch73-90k17.1 |
|
| chr24_-_25428176 Show fit | 1.92 |
ENSDART00000090010
|
phosphate regulating endopeptidase homolog, X-linked |
Network of associatons between targets according to the STRING database.
First level regulatory network of pou2f2a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 8.2 | GO:0031113 | regulation of microtubule polymerization(GO:0031113) |
| 1.0 | 5.1 | GO:1900145 | nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) |
| 1.3 | 3.8 | GO:0034214 | protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230) |
| 0.5 | 2.8 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.2 | 2.0 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.5 | 1.8 | GO:0021557 | oculomotor nerve development(GO:0021557) |
| 0.0 | 1.7 | GO:0010324 | membrane invagination(GO:0010324) |
| 0.1 | 1.5 | GO:0051452 | vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
| 0.1 | 1.5 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.5 | 1.4 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.5 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 3.8 | GO:0030496 | midbody(GO:0030496) |
| 0.3 | 3.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 3.3 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.1 | 1.8 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.1 | 1.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 1.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.3 | 1.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.0 | 1.3 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.1 | 1.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 1.6 | 4.8 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 1.0 | 3.8 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.2 | 3.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 2.5 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 2.1 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629) |
| 0.0 | 1.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 1.6 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 1.5 | GO:0051117 | ATPase binding(GO:0051117) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.1 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 0.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.5 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 4.8 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.1 | 2.8 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.0 | 1.9 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.1 | 1.6 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 1.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 1.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.3 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.1 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.1 | 1.1 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |