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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pitx2

Z-value: 0.59

Motif logo

Transcription factors associated with pitx2

Gene Symbol Gene ID Gene Info
ENSDARG00000036194 paired-like homeodomain 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pitx2dr11_v1_chr14_+_36218072_36218072-0.223.8e-01Click!

Activity profile of pitx2 motif

Sorted Z-values of pitx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_33216945 1.10 ENSDART00000134029
si:ch211-125e6.12
chr2_+_6253246 1.08 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr24_-_10006158 0.97 ENSDART00000106244
zgc:171750
chr7_+_24114694 0.88 ENSDART00000127177
mitochondrial ribosomal protein L52
chr7_+_24115082 0.83 ENSDART00000182718
mitochondrial ribosomal protein L52
chr19_+_28284120 0.74 ENSDART00000103862
mitochondrial ribosomal protein L36
chr2_-_3419890 0.67 ENSDART00000055618
IBA57, iron-sulfur cluster assembly
chr3_-_3448095 0.63 ENSDART00000078886
si:dkey-46g23.5
chr2_+_37295088 0.62 ENSDART00000056519
G protein-coupled receptor 160
chr15_-_8319988 0.60 ENSDART00000137552
si:ch211-113p18.3
chr1_-_8651718 0.57 ENSDART00000133319
actin, beta 1
chr15_+_37545855 0.54 ENSDART00000099456
presenilin enhancer gamma secretase subunit
chr10_-_43771447 0.51 ENSDART00000052307
arrestin domain containing 3b
chr1_+_55755304 0.51 ENSDART00000144983
trans-2,3-enoyl-CoA reductase b
chr3_-_40528333 0.50 ENSDART00000193047
actin, beta 2
chr8_-_21372446 0.50 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr12_+_48390715 0.49 ENSDART00000149351
stearoyl-CoA desaturase (delta-9-desaturase)
chr9_+_14028157 0.49 ENSDART00000134603
si:ch211-67e16.4
chr9_-_23747264 0.47 ENSDART00000141461
ENSDART00000010311
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr5_-_15948833 0.45 ENSDART00000051649
ENSDART00000124467
X-box binding protein 1
chr19_-_40186328 0.43 ENSDART00000087474
EF-hand calcium binding domain 1
chr4_+_11464255 0.43 ENSDART00000008584
GDP dissociation inhibitor 2
chr9_+_1365747 0.42 ENSDART00000140917
ENSDART00000036605
protein kinase, interferon-inducible double stranded RNA dependent activator
chr21_+_11367253 0.42 ENSDART00000091835
general transcription factor IIIC, polypeptide 5
chr12_+_17106117 0.39 ENSDART00000149990
actin, alpha 2, smooth muscle, aorta
chr4_-_73256421 0.36 ENSDART00000174158

chr5_+_13891202 0.36 ENSDART00000193992
hexokinase 2
chr5_+_62052538 0.35 ENSDART00000141574
si:dkey-35m8.1
chr18_+_20482369 0.35 ENSDART00000100668
kelch repeat and BTB (POZ) domain containing 4
chr5_+_62052750 0.35 ENSDART00000192103
ENSDART00000181866
si:dkey-35m8.1
chr9_+_34127005 0.34 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr10_+_14982977 0.33 ENSDART00000140869
si:dkey-88l16.3
chr8_+_27807974 0.33 ENSDART00000078509
capping protein (actin filament) muscle Z-line, alpha 1b
chr25_-_17357165 0.32 ENSDART00000064573
SET domain containing 6
chr14_-_15699528 0.32 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr19_+_19989380 0.30 ENSDART00000142841
oxysterol binding protein-like 3a
chr18_-_12270845 0.30 ENSDART00000143923
ENSDART00000125555
ENSDART00000062360
ENSDART00000062216
nucleoporin 205
chr16_+_33902006 0.30 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr5_+_37749503 0.30 ENSDART00000148586
D4, zinc and double PHD fingers family 2
chr15_-_25584888 0.29 ENSDART00000127571
si:dkey-54n8.2
chr1_-_57172294 0.29 ENSDART00000063774
Rac family small GTPase 1, like
chr16_-_30847192 0.29 ENSDART00000191106
ENSDART00000128158
protein tyrosine kinase 2ab
chr10_-_45029041 0.28 ENSDART00000167878
polymerase (DNA directed), mu
chr5_-_20491198 0.28 ENSDART00000183051
ENSDART00000144232
FIC domain containing
chr15_+_37546391 0.26 ENSDART00000186625
presenilin enhancer gamma secretase subunit
chr13_+_43400443 0.26 ENSDART00000084321
dishevelled-binding antagonist of beta-catenin 2
chr5_-_23117078 0.26 ENSDART00000051529
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr5_+_58687541 0.26 ENSDART00000083015
ENSDART00000181902
coiled-coil domain containing 84
chr11_+_5926850 0.25 ENSDART00000104364
ribosomal protein S15
chr22_-_18491813 0.25 ENSDART00000105419
si:ch211-212d10.2
chr16_-_17258111 0.25 ENSDART00000079497
EMG1 N1-specific pseudouridine methyltransferase
chr11_-_36051004 0.25 ENSDART00000025033
glutathione peroxidase 1a
chr17_-_53328043 0.24 ENSDART00000171082
exonuclease 3'-5' domain containing 1
chr14_+_44545092 0.24 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr1_+_7546259 0.24 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr25_-_26833100 0.24 ENSDART00000014052
nei-like DNA glycosylase 1
chr9_+_22631672 0.24 ENSDART00000101770
ENSDART00000126015
ENSDART00000145005
ets variant 5a
chr6_-_21091948 0.23 ENSDART00000057348
inhibin, alpha
chr8_-_54304381 0.23 ENSDART00000184177
rhodopsin
chr13_+_24280380 0.22 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr14_+_555674 0.21 ENSDART00000172137
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr12_+_47917971 0.21 ENSDART00000185933
thymus, brain and testes associated
chr23_+_44349252 0.21 ENSDART00000097644
eph receptor B4b
chr7_-_19369002 0.21 ENSDART00000165680
netrin 4
chr22_-_9889413 0.21 ENSDART00000081450
si:dkey-253d23.5
chr20_+_263056 0.21 ENSDART00000132669
tubulin, epsilon 1
chr19_-_28283844 0.20 ENSDART00000151756
ENSDART00000079104
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr12_+_48216662 0.20 ENSDART00000187369
leucine rich repeat containing 20
chr9_+_22632126 0.20 ENSDART00000139434
ets variant 5a
chr4_-_9579299 0.20 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr11_-_26375575 0.20 ENSDART00000079255
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr14_-_897874 0.20 ENSDART00000167395
regulator of G protein signaling 14a
chr9_+_54695981 0.19 ENSDART00000183605
RAB9A, member RAS oncogene family
chr13_+_36958086 0.19 ENSDART00000024386
FERM domain containing 6
chr11_+_6456146 0.19 ENSDART00000036939
growth arrest and DNA-damage-inducible, beta a
chr17_+_16046314 0.19 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr6_+_13083146 0.17 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr17_+_16046132 0.17 ENSDART00000155005
si:ch73-204p21.2
chr23_-_36313431 0.17 ENSDART00000125860
nuclear factor, erythroid 2
chr25_+_14398650 0.17 ENSDART00000130548
cytokine induced apoptosis inhibitor 1
chr19_+_34742706 0.17 ENSDART00000103276
family with sequence similarity 206, member A
chr15_-_20024205 0.17 ENSDART00000161379
autism susceptibility candidate 2b
chr17_+_24445818 0.17 ENSDART00000139963
UDP-glucose pyrophosphorylase 2b
chr7_+_38588866 0.16 ENSDART00000015682
NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase)
chr25_+_25124684 0.16 ENSDART00000167542
lactate dehydrogenase A4
chr1_+_33383644 0.16 ENSDART00000187194
dehydrogenase/reductase (SDR family) X-linked
chr20_+_50052627 0.16 ENSDART00000188799
cleavage and polyadenylation specific factor 2
chr6_+_2093206 0.15 ENSDART00000114314
transglutaminase 2b
chr20_+_50052116 0.15 ENSDART00000047212
cleavage and polyadenylation specific factor 2
chr23_+_39413163 0.15 ENSDART00000184254
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr17_-_16342388 0.14 ENSDART00000017930
potassium channel, subfamily K, member 13a
chr21_+_13205859 0.14 ENSDART00000102253
spectrin alpha, non-erythrocytic 1
chr1_-_44812014 0.14 ENSDART00000139044
si:dkey-9i23.8
chr25_-_35047838 0.14 ENSDART00000155060

chr19_-_15855427 0.14 ENSDART00000133059
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr6_-_54179860 0.13 ENSDART00000164283
ribosomal protein S10
chr20_-_25369767 0.13 ENSDART00000180278
intersectin 2a
chr1_-_12394048 0.13 ENSDART00000146067
ENSDART00000134708
sodium channel and clathrin linker 1
chr21_+_3854414 0.13 ENSDART00000122699
mitoguardin 2
chr21_-_39177564 0.13 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr6_+_29217392 0.12 ENSDART00000006386
ATPase Na+/K+ transporting subunit beta 1a
chr25_+_26844028 0.12 ENSDART00000127274
ENSDART00000156179
semaphorin 7A
chr10_+_15777258 0.12 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr10_+_15777064 0.12 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr4_+_8168514 0.12 ENSDART00000150830
ninjurin 2
chr2_-_6292510 0.12 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr24_-_21258945 0.12 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr24_-_24168475 0.12 ENSDART00000139369
ENSDART00000080671
eukaryotic translation initiation factor 1A, X-linked, b
chr6_-_39903393 0.12 ENSDART00000085945
Ts translation elongation factor, mitochondrial
chr23_+_22267374 0.12 ENSDART00000079035
RAP1 GTPase activating protein
chr4_-_74109792 0.12 ENSDART00000174320
zgc:154045
chr20_-_20533865 0.11 ENSDART00000125039
SIX homeobox 6b
chr23_+_10396842 0.11 ENSDART00000167593
ENSDART00000125103
eukaryotic translation initiation factor 4Ba
chr8_-_47844456 0.11 ENSDART00000145429
si:dkeyp-104h9.5
chr11_-_18468570 0.11 ENSDART00000155474
ENSDART00000193869
FYVE, RhoGEF and PH domain containing 5a
chr16_-_21692024 0.11 ENSDART00000123597
si:ch211-154o6.2
chr5_+_26075230 0.11 ENSDART00000098473
Kruppel-like factor 9
chr3_+_37574885 0.11 ENSDART00000055225
wingless-type MMTV integration site family, member 9B
chr1_-_43987873 0.11 ENSDART00000108821

chr8_-_22508055 0.11 ENSDART00000101616
si:ch211-261n11.5
chr15_+_5973909 0.11 ENSDART00000126886
ENSDART00000189618
immunoglobulin superfamily, member 5b
chr5_+_27421639 0.10 ENSDART00000146285
cytochrome b561 family, member A3a
chr8_-_23612462 0.10 ENSDART00000025024
solute carrier family 38, member 5b
chr4_-_77551860 0.10 ENSDART00000188176

chr13_+_36984794 0.10 ENSDART00000137328
FERM domain containing 6
chr16_+_20167811 0.10 ENSDART00000004031
2-hydroxyacyl-CoA lyase 1
chr1_-_37383741 0.10 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr9_-_53537989 0.10 ENSDART00000114022
SLIT and NTRK-like family, member 5b
chr14_-_32884138 0.09 ENSDART00000105726
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr11_-_270210 0.09 ENSDART00000005217
ENSDART00000172779
aminolevulinate, delta-, synthase 1
chr5_+_24287927 0.09 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr2_-_2096055 0.09 ENSDART00000126566
solute carrier family 22, member 23
chr7_+_828289 0.09 ENSDART00000173796
cabz01076234.2
chr1_-_8966046 0.09 ENSDART00000136198
suppressor of cytokine signaling 1b
chr7_-_66864756 0.09 ENSDART00000184462
ENSDART00000189424
adenosine monophosphate deaminase 3a
chr12_+_30706158 0.09 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr3_+_52806347 0.09 ENSDART00000168151
ENSDART00000098826
LIM homeobox transcription factor 1, alpha-like
chr25_+_35019693 0.09 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr12_+_28995942 0.09 ENSDART00000076334
vertebrate ancient long opsin b
chr14_-_40821411 0.08 ENSDART00000166621
E74-like ETS transcription factor 1
chr11_-_1933793 0.08 ENSDART00000186850
Fas apoptotic inhibitory molecule 2b
chr6_-_11812224 0.08 ENSDART00000150989
membrane-associated ring finger (C3HC4) 7
chr23_+_9220436 0.08 ENSDART00000033663
ENSDART00000139870
ribosomal protein S21
chr16_-_50952266 0.08 ENSDART00000165408
si:dkeyp-97a10.3
chr19_+_12762887 0.08 ENSDART00000139909
melanocortin 5a receptor
chr11_+_6115621 0.08 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b
chr8_+_694218 0.08 ENSDART00000147753
ring finger protein 165b
chr14_-_2004291 0.08 ENSDART00000114039
protocadherin 2 gamma 5
chr1_-_37383539 0.08 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr5_-_26493253 0.08 ENSDART00000088222
ARVCF, delta catenin family member b
chr14_+_6423973 0.08 ENSDART00000051556
ATP-binding cassette, sub-family A (ABC1), member 1B
chr23_-_15330168 0.08 ENSDART00000035865
ENSDART00000143635
sulfatase 2b
chr3_-_7940522 0.08 ENSDART00000159710
ENSDART00000167201
tripartite motif containing 35-25
chr11_-_28148033 0.08 ENSDART00000177182
lactamase, beta-like 1b
chr21_-_22715297 0.08 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr8_+_17184602 0.07 ENSDART00000050228
ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr14_-_2270973 0.07 ENSDART00000180729
protocadherin 2 alpha b 9
chr7_+_37377335 0.07 ENSDART00000111842
spalt-like transcription factor 1a
chr17_-_31659670 0.07 ENSDART00000030448
visual system homeobox 2
chr18_+_507835 0.07 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr11_+_6116096 0.07 ENSDART00000159680
nuclear receptor subfamily 2, group F, member 6b
chr12_+_316238 0.07 ENSDART00000187492
recoverin b
chr10_+_26926654 0.07 ENSDART00000078980
ENSDART00000100289
RAB1B, member RAS oncogene family b
chr10_-_7857494 0.07 ENSDART00000143215
inositol polyphosphate-5-phosphatase Ja
chr11_+_6116503 0.07 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr7_+_47316944 0.07 ENSDART00000173534
dpy-19 like C-mannosyltransferase 3
chr17_-_50331351 0.07 ENSDART00000149294
otoferlin b
chr4_-_1403077 0.07 ENSDART00000189813

chr1_-_10577945 0.06 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
transient receptor potential cation channel, subfamily C, member 5a
chr21_+_19648814 0.06 ENSDART00000048581
fibroblast growth factor 10a
chr20_-_30369598 0.06 ENSDART00000144549
allantoicase
chr4_-_40883162 0.06 ENSDART00000151978
zinc finger protein 1102
chr2_-_2020044 0.06 ENSDART00000024135
tubulin, beta 2A class IIa
chr4_+_28442223 0.06 ENSDART00000150879
zinc finger protein 1067
chr21_+_40944530 0.06 ENSDART00000022976
potassium channel tetramerization domain containing 16b
chr10_+_29137482 0.06 ENSDART00000178280
phosphatidylinositol binding clathrin assembly protein a
chr23_+_8989168 0.06 ENSDART00000034380
XK, Kell blood group complex subunit-related family, member 7
chr16_+_3067134 0.06 ENSDART00000012048
cytochrome b5 reductase 4
chr22_+_696931 0.06 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr6_-_55354004 0.06 ENSDART00000165911
PDX1 C-terminal inhibiting factor 1
chr16_-_28836523 0.06 ENSDART00000108596
ENSDART00000142920
perilipin 6
chr20_-_42534504 0.06 ENSDART00000132310
regulatory factor X, 6
chr10_-_43392267 0.06 ENSDART00000142872
EGF-like repeats and discoidin I-like domains 3b
chr17_-_24714837 0.06 ENSDART00000154871
si:ch211-15d5.11
chr17_+_21760032 0.06 ENSDART00000190425
IKAROS family zinc finger 5
chr22_+_19486711 0.06 ENSDART00000144389
ENSDART00000139256
ENSDART00000160855
si:dkey-78l4.10
chr7_+_19738665 0.06 ENSDART00000089333
triokinase/FMN cyclase
chr13_+_669177 0.06 ENSDART00000190085

chr25_+_3788074 0.06 ENSDART00000154008
chitinase domain containing 1
chr10_-_25204034 0.06 ENSDART00000161100
si:ch211-214k5.6
chr15_-_47848544 0.06 ENSDART00000098711
eukaryotic translation initiation factor 3, subunit K
chr5_-_67145505 0.06 ENSDART00000011295
retinal outer segment membrane protein 1a
chr17_+_28624321 0.06 ENSDART00000122260
HEAT repeat containing 5a
chr4_-_44500201 0.06 ENSDART00000150460
si:dkeyp-100h4.7
chr20_-_54564018 0.06 ENSDART00000099832
zgc:153012
chr17_+_44756247 0.06 ENSDART00000153773
CLOCK-interacting pacemaker a
chr23_-_24856025 0.06 ENSDART00000142171
synaptotagmin VIa
chr4_+_5848229 0.06 ENSDART00000161101
ENSDART00000067357
LYR motif containing 5a
chr14_-_3132188 0.06 ENSDART00000172259
si:zfos-1069f5.1
chr23_+_23232136 0.06 ENSDART00000126479
ENSDART00000187764
pleckstrin homology domain containing, family N member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of pitx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 1.1 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.2 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.0 0.1 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.3 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0000256 allantoin catabolic process(GO:0000256)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0098773 skin epidermis development(GO:0098773)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 1.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.0 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.0 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling