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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pgr

Z-value: 0.52

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Transcription factors associated with pgr

Gene Symbol Gene ID Gene Info
ENSDARG00000035966 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pgrdr11_v1_chr18_+_41820039_418200390.728.4e-04Click!

Activity profile of pgr motif

Sorted Z-values of pgr motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_57311901 1.50 ENSDART00000149397
mycbp associated protein
chr16_-_41807397 1.42 ENSDART00000138577
si:dkey-199f5.7
chr17_-_24838927 1.35 ENSDART00000123259

chr15_-_19677511 1.23 ENSDART00000043743
si:dkey-4p15.3
chr6_+_515181 0.93 ENSDART00000171374
si:ch73-379f7.5
chr7_+_23997518 0.92 ENSDART00000173372
coiled-coil domain containing 166
chr16_-_41840668 0.91 ENSDART00000146150
si:dkey-199f5.4
chr2_-_14272083 0.88 ENSDART00000169986
Tctex1 domain containing 1
chr19_+_43978814 0.88 ENSDART00000102314
naked cuticle homolog 3
chr16_-_41059329 0.82 ENSDART00000145556
si:dkey-201i6.8
chr8_+_25902170 0.80 ENSDART00000193130
ras homolog gene family, member Ab
chr6_+_475264 0.79 ENSDART00000193615

chr24_+_33589667 0.76 ENSDART00000152097
dynein, axonemal, heavy chain 5 like
chr18_+_1145571 0.76 ENSDART00000135055
REC114 meiotic recombination protein
chr14_-_36862745 0.75 ENSDART00000109293
ring finger protein 130
chr10_+_26669177 0.72 ENSDART00000143402
si:ch73-52f15.5
chr17_-_12407106 0.71 ENSDART00000183540
ankyrin repeat and EF-hand domain containing 1b
chr13_-_37619159 0.66 ENSDART00000186348
zgc:152791
chr7_+_49681040 0.65 ENSDART00000176372
ENSDART00000192172
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr22_-_24285432 0.64 ENSDART00000164083
si:ch211-117l17.4
chr4_-_16406737 0.64 ENSDART00000013085
decorin
chr2_+_26288301 0.64 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr20_-_43462190 0.61 ENSDART00000100697
Pim proto-oncogene, serine/threonine kinase, related 133
chr2_-_29485408 0.60 ENSDART00000013411
carbonic anhydrase
chr18_+_5547185 0.59 ENSDART00000193977
nicotinamide nucleotide transhydrogenase 2
chr6_-_49078263 0.58 ENSDART00000032982
solute carrier family 5 (iodide transporter), member 8-like
chr11_+_35364445 0.57 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr12_-_5188413 0.57 ENSDART00000161988
FRA10A associated CGG repeat 1
chr8_+_53311965 0.52 ENSDART00000130104
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr20_+_38837238 0.50 ENSDART00000061334
intraflagellar transport 172
chr13_-_36535128 0.49 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr15_-_17870090 0.49 ENSDART00000155066
activating transcription factor 5b
chr9_-_42696408 0.49 ENSDART00000144744
collagen, type V, alpha 2a
chr6_+_7250824 0.47 ENSDART00000177226
DAZ interacting zinc finger protein 1
chr20_-_26420939 0.47 ENSDART00000110883
A kinase (PRKA) anchor protein 12b
chr5_+_69981453 0.47 ENSDART00000143860
si:ch211-154e10.1
chr16_-_35579200 0.46 ENSDART00000162172
Scm polycomb group protein homolog 1
chr25_-_12982193 0.45 ENSDART00000159617
chemokine (C-C motif) ligand 39, duplicate 5
chr14_-_25949713 0.44 ENSDART00000181455
secreted protein, acidic, cysteine-rich (osteonectin)
chr18_+_16744307 0.43 ENSDART00000179872
ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr20_-_26421112 0.42 ENSDART00000183767
ENSDART00000182330
A kinase (PRKA) anchor protein 12b
chr17_+_26815021 0.42 ENSDART00000086885
acetylserotonin O-methyltransferase 2
chr25_-_6420800 0.42 ENSDART00000153768
protein tyrosine phosphatase, non-receptor type 9, a
chr19_+_48251273 0.42 ENSDART00000157424

chr9_-_22831836 0.42 ENSDART00000142585
nebulin
chr1_-_10914523 0.41 ENSDART00000007013
dystrophin
chr2_-_50053006 0.40 ENSDART00000083654
si:ch211-106n13.3
chr5_+_20693724 0.40 ENSDART00000141368
si:ch211-240b21.2
chr5_-_51756210 0.40 ENSDART00000163464
LHFPL tetraspan subfamily member 2b
chr18_+_9171778 0.40 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr9_-_46842179 0.39 ENSDART00000054137
insulin-like growth factor binding protein 5b
chr8_-_12468744 0.38 ENSDART00000135019
si:dkeyp-51b7.3
chr10_+_8968203 0.38 ENSDART00000110443
ENSDART00000080772
follistatin b
chr20_+_16750177 0.38 ENSDART00000185357
calmodulin 1b
chr23_-_26077038 0.37 ENSDART00000126299
GDP dissociation inhibitor 1
chr5_-_25174420 0.37 ENSDART00000141554
ATP-binding cassette, sub-family A (ABC1), member 2
chr21_-_14803554 0.37 ENSDART00000121853
si:dkey-11o18.5
chr1_-_51615437 0.36 ENSDART00000152185
ENSDART00000152237
ENSDART00000129052
ENSDART00000152595
si:dkey-202b17.4
chr5_-_28029558 0.35 ENSDART00000078649
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr12_-_1951233 0.34 ENSDART00000005676
ENSDART00000127937
SRY (sex determining region Y)-box 9a
chr4_+_12358822 0.34 ENSDART00000172557
ENSDART00000150627
Pim proto-oncogene, serine/threonine kinase, related 168
chr5_-_67911111 0.34 ENSDART00000051833
GS homeobox 1
chr20_+_35445462 0.33 ENSDART00000124497
tudor domain containing 6
chr8_-_36475328 0.33 ENSDART00000048448
si:busm1-266f07.2
chr14_-_2602445 0.33 ENSDART00000166910
eukaryotic translation termination factor 1a
chr21_+_18353703 0.32 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr24_+_23742690 0.32 ENSDART00000130162
transcription factor 24
chr20_+_9785952 0.32 ENSDART00000152403
DDHD domain containing 1b
chr20_+_539852 0.31 ENSDART00000185994
dermatan sulfate epimerase
chr18_+_21061216 0.31 ENSDART00000141739
family with sequence similarity 169, member B
chr2_+_47581997 0.31 ENSDART00000112579
secretogranin II (chromogranin C), b
chr16_+_16968682 0.31 ENSDART00000111074
si:ch211-120k19.1
chr21_+_25187210 0.30 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
chr17_+_26783828 0.30 ENSDART00000154921
La ribonucleoprotein domain family, member 1B
chr8_+_20951590 0.30 ENSDART00000138728
si:dkeyp-82a1.1
chr6_-_39764995 0.29 ENSDART00000085277
phosphofructokinase, muscle b
chr19_-_27542433 0.29 ENSDART00000136414
si:ch211-152p11.4
chr2_+_44571200 0.29 ENSDART00000098132
kelch-like family member 24a
chr15_-_21678634 0.29 ENSDART00000061139
beta-carotene oxygenase 2b
chr9_+_19489514 0.29 ENSDART00000152032
ENSDART00000114256
ENSDART00000190572
ENSDART00000147571
ENSDART00000151918
ENSDART00000152034
si:ch211-140m22.7
chr2_-_37896965 0.29 ENSDART00000129852
hexose-binding lectin 1
chr16_+_16969060 0.29 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr10_+_44146287 0.28 ENSDART00000162176
G protein-coupled receptor kinase 3
chr20_+_29634653 0.28 ENSDART00000101556
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2b
chr20_-_34711528 0.28 ENSDART00000061555
si:ch211-63o20.7
chr1_-_35924495 0.28 ENSDART00000184424
SMAD family member 1
chr7_+_52761841 0.28 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr22_+_20427170 0.28 ENSDART00000136744
forkhead box Q2
chr20_+_18580176 0.28 ENSDART00000185310
si:dkeyp-72h1.1
chr1_-_45614481 0.27 ENSDART00000148413
activating transcription factor 7 interacting protein
chr12_-_19007834 0.27 ENSDART00000153248
chondroadherin-like b
chr2_+_10134345 0.27 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr6_-_8489810 0.27 ENSDART00000124643
RAS protein activator like 3
chr25_+_4541211 0.27 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr16_-_51271962 0.27 ENSDART00000164021
ENSDART00000046420
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr15_-_32383529 0.27 ENSDART00000028349
complement component 4
chr23_+_25210953 0.26 ENSDART00000132799
si:dkey-151g10.3
chr9_+_12948511 0.26 ENSDART00000135797
si:dkey-230p4.1
chr2_+_29976419 0.26 ENSDART00000056748
engrailed homeobox 2b
chr7_-_27033080 0.26 ENSDART00000173516
nucleobindin 2a
chr24_-_22702017 0.26 ENSDART00000179403
catenin (cadherin-associated protein), delta 2a
chr1_+_144284 0.26 ENSDART00000064061
protein Z, vitamin K-dependent plasma glycoprotein b
chr18_+_19120984 0.26 ENSDART00000141501
si:dkey-242h9.3
chr15_+_1796313 0.25 ENSDART00000126253
family with sequence similarity 124B
chr21_-_25601648 0.25 ENSDART00000042578
EGF containing fibulin extracellular matrix protein 2b
chr15_+_44472356 0.25 ENSDART00000155763
ENSDART00000028011
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr13_-_36391496 0.25 ENSDART00000100217
ENSDART00000140243
actinin, alpha 1
chr17_-_28097760 0.24 ENSDART00000149861
lysine (K)-specific demethylase 1a
chr17_-_28100741 0.24 ENSDART00000180532
lysine (K)-specific demethylase 1a
chr3_-_2589704 0.24 ENSDART00000187239
si:dkey-217f16.5
chr24_-_33756003 0.24 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr20_+_6630540 0.24 ENSDART00000138361
tensin 3, tandem duplicate 2
chr5_+_30680804 0.24 ENSDART00000078049
PDZ domain containing 3b
chr13_+_35745572 0.24 ENSDART00000159690
G protein-coupled receptor 75
chr1_-_23274038 0.24 ENSDART00000181658
replication factor C (activator 1) 1
chr15_+_38046435 0.24 ENSDART00000156481
si:ch73-380l3.4
chr4_-_11577253 0.23 ENSDART00000144452
neuroepithelial cell transforming 1
chr6_+_11250033 0.23 ENSDART00000065411
ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr9_+_44832032 0.23 ENSDART00000002633
frizzled related protein
chr7_+_46368520 0.23 ENSDART00000192821
zinc finger protein 536
chr4_-_52165969 0.23 ENSDART00000171130
si:dkeyp-44b5.4
chr7_-_74090168 0.23 ENSDART00000050528
tyrosinase-related protein 1a
chr25_+_3564220 0.23 ENSDART00000170005
zgc:194202
chr1_-_26398361 0.22 ENSDART00000160183
pyrophosphatase (inorganic) 2
chr8_+_68864 0.22 ENSDART00000164574
proline rich 16
chr19_-_10656667 0.22 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
oleoyl-ACP hydrolase
chr6_+_11249706 0.22 ENSDART00000186547
ENSDART00000193287
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr6_-_54290227 0.22 ENSDART00000050483
SAM pointed domain containing ETS transcription factor
chr17_-_7501916 0.22 ENSDART00000141987
si:ch211-278p9.3
chr19_-_29437108 0.22 ENSDART00000052108
ENSDART00000074497
fibronectin type III domain containing 5b
chr5_+_22459087 0.21 ENSDART00000134781

chr23_+_30048849 0.21 ENSDART00000126027
urotensin 2, alpha
chr20_+_33904258 0.21 ENSDART00000170930
retinoid X receptor, gamma b
chr3_+_42497814 0.21 ENSDART00000184653

chr3_-_29977495 0.21 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr6_+_41096058 0.20 ENSDART00000028373
FK506 binding protein 5
chr13_+_28495419 0.20 ENSDART00000025583
fibroblast growth factor 8a
chr3_-_42125655 0.20 ENSDART00000040753
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr4_-_20181964 0.20 ENSDART00000022539
fibrinogen-like 2a
chr22_-_15602593 0.20 ENSDART00000036075
tropomyosin 4a
chr2_-_32366287 0.20 ENSDART00000144758
upstream binding transcription factor, like
chr9_-_8454060 0.20 ENSDART00000110158
insulin receptor substrate 2b
chr7_-_51710015 0.20 ENSDART00000009184
histone deacetylase 8
chr10_+_34394454 0.19 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr10_+_6121558 0.19 ENSDART00000166799
ENSDART00000157947
talin 1
chr20_-_39735952 0.19 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr3_+_32698424 0.19 ENSDART00000055340
FUS RNA binding protein
chr23_+_7379728 0.19 ENSDART00000012194
GATA binding protein 5
chr14_-_7141550 0.19 ENSDART00000172020
tRNA phosphotransferase 1
chr9_+_31752628 0.19 ENSDART00000060054
integrin, beta-like 1
chr9_-_14992730 0.19 ENSDART00000137117
par-3 family cell polarity regulator beta b
chr21_+_10866421 0.19 ENSDART00000137858
alpha-kinase 2
chr13_-_32577386 0.19 ENSDART00000016535
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr5_-_52215926 0.19 ENSDART00000163973
ENSDART00000193602
leucyl/cystinyl aminopeptidase
chr2_+_45159855 0.18 ENSDART00000056333

chr6_-_11136786 0.18 ENSDART00000186522
myosin X-like 1
chr8_-_11229523 0.18 ENSDART00000002164
unc-45 myosin chaperone B
chr23_+_21663631 0.18 ENSDART00000066125
dehydrogenase/reductase (SDR family) member 3a
chr6_-_18400548 0.18 ENSDART00000179797
ENSDART00000164891
tripartite motif containing 25
chr21_+_25221940 0.18 ENSDART00000108972
syncollin, tandem duplicate 1
chr2_+_258698 0.18 ENSDART00000181330
ENSDART00000181645
PH domain and leucine rich repeat protein phosphatase 1
chr6_-_39765546 0.18 ENSDART00000185767
phosphofructokinase, muscle b
chr18_+_30567945 0.18 ENSDART00000078894
interferon regulatory factor 8
chr19_-_18626515 0.17 ENSDART00000160624
ribosomal protein S18
chr5_+_61863996 0.17 ENSDART00000082879
symplekin
chr18_-_39200557 0.17 ENSDART00000132367
ENSDART00000183672
si:ch211-235f12.2
mitogen-activated protein kinase 6
chr10_+_25204626 0.17 ENSDART00000024514
cysteine and histidine-rich domain (CHORD) containing 1b
chr19_-_18626952 0.17 ENSDART00000168004
ENSDART00000162034
ENSDART00000165486
ENSDART00000167971
ribosomal protein S18
chr13_+_39188737 0.16 ENSDART00000083641
family with sequence similarity 135, member A
chr22_-_38508112 0.16 ENSDART00000192004
kinesin light chain 4
chr12_-_33646010 0.16 ENSDART00000111259
transmembrane protein 94
chr23_-_45504991 0.16 ENSDART00000148761
collagen type XXIV alpha 1
chr23_+_2760573 0.16 ENSDART00000129719
DNA topoisomerase I
chr6_-_40429411 0.16 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
chr6_-_60031693 0.16 ENSDART00000160275

chr5_-_21422390 0.16 ENSDART00000144198
teneurin transmembrane protein 1
chr11_-_4787083 0.15 ENSDART00000159425
si:ch211-63i20.3
chr25_-_210730 0.15 ENSDART00000187580

chr7_-_44672095 0.15 ENSDART00000073745
CKLF-like MARVEL transmembrane domain containing 4
chr14_-_25985698 0.15 ENSDART00000172909
ENSDART00000123053
antioxidant 1 copper chaperone
chr17_+_25677458 0.15 ENSDART00000029703
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr18_-_2639351 0.15 ENSDART00000168106
RELT, TNF receptor
chr3_-_58582663 0.15 ENSDART00000180055

chr20_-_20611063 0.14 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr20_-_30377221 0.14 ENSDART00000126229
ribosomal protein S7
chr15_-_32383340 0.14 ENSDART00000185632
complement component 4
chr21_-_26089964 0.14 ENSDART00000027848
TLC domain containing 1
chr8_+_23093155 0.14 ENSDART00000063075
zgc:100920
chr5_+_62356304 0.14 ENSDART00000148381
aspartoacylase
chr4_+_77021784 0.14 ENSDART00000135345
ENSDART00000133855
transient receptor potential cation channel, subfamily M, member 2
chr1_-_59348118 0.14 ENSDART00000170901
cytochrome P450, family 3, subfamily A, polypeptide 65
chr17_-_28100501 0.14 ENSDART00000149543
lysine (K)-specific demethylase 1a
chr5_-_41307550 0.14 ENSDART00000143446
natriuretic peptide receptor 3
chr22_-_4778018 0.14 ENSDART00000143968
si:ch73-256j6.5
chr8_+_44613135 0.14 ENSDART00000063392
LSM1, U6 small nuclear RNA associated
chr20_-_26846028 0.14 ENSDART00000136687
myosin light chain kinase family, member 4b
chr20_-_47704973 0.13 ENSDART00000174808
transcription factor AP-2 beta
chr22_+_1384104 0.13 ENSDART00000187191

chr4_-_28958601 0.13 ENSDART00000111294
zgc:174315
chr12_+_2995887 0.13 ENSDART00000189499
ENSDART00000182597
ENSDART00000184918
ENSDART00000182292
leucine rich repeat containing 45

Network of associatons between targets according to the STRING database.

First level regulatory network of pgr

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.2 0.7 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.2 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.1 0.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.3 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.5 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0043587 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.0 0.2 GO:0030890 B cell homeostasis(GO:0001782) positive regulation of B cell proliferation(GO:0030890)
0.0 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.3 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.4 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:0003315 heart rudiment formation(GO:0003315)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0008584 male gonad development(GO:0008584)
0.0 0.2 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0048752 otolith morphogenesis(GO:0032474) semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.5 GO:0034341 response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.6 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0046978 TAP1 binding(GO:0046978)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.3 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production