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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pax3a+pax3b

Z-value: 0.80

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Transcription factors associated with pax3a+pax3b

Gene Symbol Gene ID Gene Info
ENSDARG00000010192 paired box 3a
ENSDARG00000028348 paired box 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax3bdr11_v1_chr15_-_42206890_422068900.872.4e-06Click!
pax3adr11_v1_chr2_-_47431205_474312050.753.3e-04Click!

Activity profile of pax3a+pax3b motif

Sorted Z-values of pax3a+pax3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_28727763 2.57 ENSDART00000149575
DC-STAMP domain containing 1
chr20_-_2667902 2.15 ENSDART00000036373
cilia and flagella associated protein 206
chr12_-_23128746 2.02 ENSDART00000170018
armadillo repeat containing 4
chr23_-_35483163 2.02 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr12_-_20796430 1.99 ENSDART00000064339
NME/NM23 nucleoside diphosphate kinase 2a
chr25_+_32530976 1.93 ENSDART00000156190
ENSDART00000103324
S-phase cyclin A-associated protein in the ER
chr20_-_52666150 1.92 ENSDART00000146716
ENSDART00000134155
si:ch211-221n20.4
chr9_+_2507526 1.90 ENSDART00000166579
WAS/WASL interacting protein family, member 1a
chr18_+_25752592 1.90 ENSDART00000111767
si:ch211-39k3.2
chr20_-_51697437 1.90 ENSDART00000145391
si:ch211-14a11.2
chr20_-_52603094 1.85 ENSDART00000136945
ENSDART00000133798
si:dkey-235d18.6
chr20_-_52616333 1.76 ENSDART00000138348
ENSDART00000132196
si:ch211-221n20.7
chr25_-_16554757 1.72 ENSDART00000154480
si:ch211-266k8.6
chr25_-_16160494 1.62 ENSDART00000146880
si:dkey-80c24.4
chr23_+_35708730 1.62 ENSDART00000009277
tubulin, alpha 1a
chr20_-_52642504 1.61 ENSDART00000138982
ENSDART00000134999
si:ch211-221n20.2
chr24_-_29030641 1.58 ENSDART00000156643
ENSDART00000150203
ENSDART00000144631
si:ch211-287n14.3
chr6_+_49095646 1.56 ENSDART00000103385
solute carrier family 25, member 55a
chr16_+_28728347 1.42 ENSDART00000149240
si:dkey-24i24.3
chr3_-_34801041 1.42 ENSDART00000103043
N-ethylmaleimide-sensitive factor a
chr16_+_31853919 1.41 ENSDART00000133886
atrophin 1
chr19_+_31873308 1.40 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr2_+_44571200 1.39 ENSDART00000098132
kelch-like family member 24a
chr10_-_320153 1.36 ENSDART00000161493
v-akt murine thymoma viral oncogene homolog 2, like
chr7_+_20344222 1.34 ENSDART00000141186
ENSDART00000139274
plac8 onzin related protein 1
chr5_+_66353589 1.30 ENSDART00000138246
si:ch211-261c8.5
chr5_-_34185497 1.28 ENSDART00000146321
fibrinogen C domain containing 1
chr5_-_72136548 1.23 ENSDART00000007827
sepiapterin reductase a
chr23_-_12931693 1.19 ENSDART00000122176

chr13_+_2908764 1.18 ENSDART00000162362
wu:fj16a03
chr22_-_25033105 1.15 ENSDART00000124220
neuronal pentraxin receptor b
chr13_-_37653840 1.15 ENSDART00000143806
si:dkey-188i13.11
chr4_-_149334 1.11 ENSDART00000163280
TANK-binding kinase 1
chr15_-_34051457 1.11 ENSDART00000189764
si:dkey-30e9.7
chr23_-_33775145 1.09 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
Rac GTPase activating protein 1
chr23_-_40796992 1.07 ENSDART00000145116
si:dkey-194e6.2
chr19_+_23932259 1.06 ENSDART00000139040
si:dkey-222b8.1
chr3_-_55121125 1.05 ENSDART00000125092
hemoglobin, alpha embryonic 1
chr19_-_20162980 1.04 ENSDART00000184605
family with sequence similarity 221, member A
chr24_-_7632187 1.02 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr2_-_53481912 1.02 ENSDART00000189610
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr7_-_33130552 1.02 ENSDART00000127006
meiosis-specific nuclear structural 1
chr16_-_13516745 1.01 ENSDART00000145410
si:dkeyp-69b9.3
chr6_+_15762647 1.01 ENSDART00000127133
ENSDART00000128939
IQ motif containing with AAA domain 1
chr12_-_48566778 1.00 ENSDART00000063442
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_+_49668423 1.00 ENSDART00000150880
testis specific, 10
chr7_+_20344486 0.93 ENSDART00000134004
ENSDART00000139685
plac8 onzin related protein 1
chr8_+_15239549 0.88 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr25_+_13791627 0.87 ENSDART00000159278
zgc:92873
chr23_-_4925641 0.82 ENSDART00000140861
ENSDART00000060718
tafazzin
chr5_-_26181863 0.79 ENSDART00000098500
coiled-coil domain containing 125
chr11_-_22372072 0.79 ENSDART00000065996
transmembrane protein 183A
chr8_+_48848200 0.77 ENSDART00000130673
tumor protein p73
chr24_+_7336807 0.77 ENSDART00000137010
lysine (K)-specific methyltransferase 2Ca
chr17_+_2734331 0.75 ENSDART00000067542
potassium channel, subfamily K, member 10b
chr16_+_32995882 0.74 ENSDART00000170157
protease, serine, 35
chr23_-_40779334 0.73 ENSDART00000141432
si:dkeyp-27c8.1
chr1_+_12195700 0.72 ENSDART00000040307
tudor domain containing 7 a
chr9_+_19095023 0.72 ENSDART00000110457
ENSDART00000099426
ENSDART00000137087
cytokine receptor family member b1
chr16_+_9713850 0.72 ENSDART00000164103
extracellular matrix protein 1b
chr14_-_38878356 0.71 ENSDART00000173082
ENSDART00000039788
ubiquinol-cytochrome c reductase, complex III subunit VII
chr23_+_42304602 0.69 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr11_-_24347644 0.69 ENSDART00000089777
si:ch211-15p9.2
chr15_-_17213723 0.67 ENSDART00000156892
integrin, alpha E, tandem duplicate 1
chr2_-_42065069 0.66 ENSDART00000140188
centrosome and spindle pole associated protein 1b
chr2_+_17181777 0.66 ENSDART00000112063
prostaglandin E receptor 4 (subtype EP4) c
chr25_-_4525081 0.65 ENSDART00000184347
p53-induced death domain protein 1
chr3_+_6469754 0.65 ENSDART00000185809
nucleoporin 85
chr11_-_6048490 0.65 ENSDART00000066164
plasmalemma vesicle associated protein b
chr2_-_30668580 0.65 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr3_-_14571514 0.64 ENSDART00000137197
SWIM-type zinc finger 7 associated protein 1
chr23_+_2421313 0.63 ENSDART00000126038
t-complex 1
chr23_+_28092083 0.58 ENSDART00000053958
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr21_+_10782013 0.58 ENSDART00000146248
zinc finger protein 532
chr19_-_9882821 0.58 ENSDART00000147128
calcium channel, voltage-dependent, gamma subunit 7a
chr18_+_2189211 0.57 ENSDART00000170827
cell cycle progression 1
chr7_+_33130639 0.57 ENSDART00000142450
ENSDART00000173967
ENSDART00000173832
zgc:153219
si:ch211-194p6.7
chr2_+_11685742 0.56 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr11_-_497854 0.55 ENSDART00000104520
CCHC-type zinc finger, nucleic acid binding protein b
chr12_-_18519822 0.55 ENSDART00000152780
testis expressed 2, like
chr23_+_36130883 0.50 ENSDART00000103132
homeobox C4a
chr22_-_10826 0.49 ENSDART00000125700
mitochondrial ribosomal protein L20
chr1_-_59348118 0.49 ENSDART00000170901
cytochrome P450, family 3, subfamily A, polypeptide 65
chr6_-_31233696 0.47 ENSDART00000079173
leptin receptor
chr18_-_5111449 0.46 ENSDART00000046902
programmed cell death 10a
chr18_+_26829086 0.46 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr15_+_24588963 0.44 ENSDART00000155075
zgc:198241
chr25_-_13839743 0.43 ENSDART00000158780
mitogen-activated protein kinase 8 interacting protein 1a
chr15_-_23342752 0.43 ENSDART00000020425
melanoma cell adhesion molecule b
chr19_-_24163845 0.42 ENSDART00000133277
perforin 1.2
chr24_+_792429 0.41 ENSDART00000082523
inositol(myo)-1(or 4)-monophosphatase 2
chr17_-_23674495 0.41 ENSDART00000122209
phosphatase and tensin homolog A
chr14_+_38878482 0.40 ENSDART00000043317
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr5_-_42060121 0.40 ENSDART00000148021
ENSDART00000147407
centromere protein V
chr5_-_29587351 0.38 ENSDART00000136446
ENSDART00000051434
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr19_+_33093395 0.38 ENSDART00000019459
family with sequence similarity 91, member A1
chr11_-_497680 0.38 ENSDART00000154888
CCHC-type zinc finger, nucleic acid binding protein b
chr15_+_1004680 0.38 ENSDART00000157310
si:dkey-77f5.8
chr2_+_45479841 0.37 ENSDART00000151856
si:ch211-66k16.28
chr18_+_26829362 0.37 ENSDART00000132728
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr22_-_5958066 0.36 ENSDART00000145821
si:rp71-36a1.3
chr1_+_41588170 0.36 ENSDART00000139175
si:dkey-56e3.2
chr2_+_18017000 0.35 ENSDART00000186877

chr5_-_42059869 0.33 ENSDART00000193984
centromere protein V
chr13_-_3516473 0.32 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr18_-_977075 0.32 ENSDART00000032392
dihydrodiol dehydrogenase (dimeric), like
chr13_-_33671694 0.32 ENSDART00000143945
ENSDART00000100504
zgc:163030
chr13_+_9896845 0.31 ENSDART00000169076
si:ch211-117n7.8
chr11_+_42587900 0.31 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr22_+_24378064 0.30 ENSDART00000180592

chr23_-_45504991 0.30 ENSDART00000148761
collagen type XXIV alpha 1
chr18_+_30028637 0.30 ENSDART00000139750
si:ch211-220f16.1
chr13_+_13681681 0.29 ENSDART00000057825
complement factor D (adipsin)
chr24_-_41195068 0.29 ENSDART00000121592
activin A receptor type 2Ba
chr2_+_13050225 0.29 ENSDART00000182237

chr2_+_35993404 0.28 ENSDART00000170845
laminin, gamma 2
chr5_+_23599259 0.27 ENSDART00000138902
K(lysine) acetyltransferase 5b
chr7_-_39552314 0.26 ENSDART00000134174
solute carrier family 22, member 18
chr25_-_13490744 0.25 ENSDART00000056721
lactate dehydrogenase D
chr5_-_41142768 0.25 ENSDART00000074789
zinc finger RNA binding protein
chr5_-_41142467 0.23 ENSDART00000129415
zinc finger RNA binding protein
chr12_-_19151708 0.23 ENSDART00000057124
thyrotrophic embryonic factor a
chr14_-_1955257 0.23 ENSDART00000193254
protocadherin 2 gamma 5
chr25_-_12935424 0.22 ENSDART00000160217
chemokine (C-C motif) ligand 39, duplicate 7
chr2_-_31754292 0.22 ENSDART00000192498
RALY RNA binding protein like
chr5_+_28161079 0.22 ENSDART00000141109
tachykinin receptor 1a
chr15_+_39096736 0.22 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr20_+_50852356 0.21 ENSDART00000167517
ENSDART00000168396
gephyrin b
chr23_+_40275601 0.21 ENSDART00000076876
family with sequence similarity 46, member Ab
chr17_-_3815693 0.19 ENSDART00000161207
phospholipase C beta 4
chr6_+_55428924 0.18 ENSDART00000018270
nuclear receptor coactivator 5
chr25_-_12935065 0.18 ENSDART00000167362
chemokine (C-C motif) ligand 39, duplicate 7
chr9_-_32668928 0.17 ENSDART00000135798
granzyme 3, tandem duplicate 3
chr16_+_10841163 0.16 ENSDART00000065467
death effector domain-containing 1
chr19_-_3781405 0.16 ENSDART00000170609
bloodthirsty-related gene family, member 19
chr7_-_69647988 0.16 ENSDART00000169943

chr10_+_39692241 0.16 ENSDART00000113414
kirre like nephrin family adhesion molecule 3a
chr18_+_43365890 0.15 ENSDART00000173113
si:ch211-129p13.1
chr14_+_597532 0.15 ENSDART00000159805

chr13_-_44997991 0.14 ENSDART00000115360

chr22_+_18886209 0.14 ENSDART00000144402
follistatin-like 3 (secreted glycoprotein)
chr22_+_569565 0.14 ENSDART00000037069
ubiquitin specific peptidase 49
chr5_-_26950374 0.13 ENSDART00000050542
HtrA serine peptidase 4
chr19_+_2726819 0.13 ENSDART00000187122
ENSDART00000112414
Rap guanine nucleotide exchange factor (GEF) 5a
chr23_-_41651759 0.12 ENSDART00000146808
si:ch73-184c24.1
chr5_+_38662125 0.12 ENSDART00000136949
si:dkey-58f10.13
chr2_+_39618951 0.12 ENSDART00000077108
zgc:136870
chr3_-_8265158 0.11 ENSDART00000171310
cytochrome P450, family 2, subfamily K, polypeptide 6
chr23_-_4925131 0.10 ENSDART00000138805
tafazzin
chr24_-_36175365 0.10 ENSDART00000065338
PAK1 interacting protein 1
chr7_+_6879534 0.10 ENSDART00000157731
zgc:175248
chr4_+_77076645 0.09 ENSDART00000174346

chr22_+_2228919 0.09 ENSDART00000133475
zinc finger protein 1161
chr20_+_10727022 0.08 ENSDART00000104185
si:ch211-182e10.4
chr17_+_12658411 0.08 ENSDART00000139918
GPN-loop GTPase 1
chr22_+_2473222 0.08 ENSDART00000192179

chr5_-_50781623 0.08 ENSDART00000114950
zgc:194908
chr19_+_33553586 0.07 ENSDART00000183477
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_46558521 0.07 ENSDART00000189406
si:dkey-152b24.8
chr19_+_9033376 0.07 ENSDART00000192298
ENSDART00000052915
ash1 (absent, small, or homeotic)-like (Drosophila)
chr20_+_710052 0.06 ENSDART00000166656
SUMO1/sentrin specific peptidase 6a
chr5_+_27440325 0.06 ENSDART00000185815
ENSDART00000144013
lysyl oxidase-like 2b
chr19_+_31061718 0.06 ENSDART00000145971
sclerostin domain containing 1b
chr2_-_47039762 0.06 ENSDART00000139389
si:ch211-226f6.1
chr15_+_1440364 0.06 ENSDART00000153685
interleukin 12a
chr18_-_46280578 0.06 ENSDART00000131724
phospholipase D family, member 3
chr3_-_47294365 0.05 ENSDART00000191039
TNF superfamily member 18
chr8_+_14710542 0.05 ENSDART00000132899
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr4_-_4834347 0.04 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr3_+_32615889 0.04 ENSDART00000028010
unc-119 lipid binding chaperone B homolog 2
chr1_-_28607353 0.04 ENSDART00000191210

chr5_+_37649206 0.04 ENSDART00000149151
ENSDART00000097723
spectrin, beta, non-erythrocytic 2
chr21_+_10021823 0.04 ENSDART00000163995
hect domain and RLD 7
chr5_-_67499279 0.04 ENSDART00000128050
si:dkey-251i10.3
chr15_+_26573676 0.04 ENSDART00000154905
ENSDART00000058514
solute carrier family 13 (sodium-dependent citrate transporter), member 5b
chr19_+_4059200 0.03 ENSDART00000161676
ENSDART00000172424
ENSDART00000161804
bloodthirsty-related gene family, member 25
chr19_+_33093577 0.03 ENSDART00000180317
family with sequence similarity 91, member A1
chr8_+_48603398 0.02 ENSDART00000074900
zgc:195023
chr4_-_46946643 0.01 ENSDART00000180392
ENSDART00000184563
si:dkey-16p6.1
chr2_-_59157790 0.01 ENSDART00000192303
ENSDART00000159362
finTRIM family, member 32
chr17_+_3128273 0.01 ENSDART00000122453
zgc:136872
chr22_-_24313301 0.00 ENSDART00000161480
urotensin 2 domain containing
chr15_-_25556074 0.00 ENSDART00000124677
matrix metallopeptidase 20a (enamelysin)
chr16_-_46558708 0.00 ENSDART00000128037
si:dkey-152b24.8

Network of associatons between targets according to the STRING database.

First level regulatory network of pax3a+pax3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.4 1.4 GO:0048939 Golgi vesicle docking(GO:0048211) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.2 2.3 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 1.6 GO:0021634 optic nerve formation(GO:0021634)
0.2 1.0 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.2 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.9 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 0.7 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.2 1.6 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.7 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 2.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.9 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.1 1.0 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.2 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0030719 P granule organization(GO:0030719)
0.1 0.8 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.6 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.6 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 2.6 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.7 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 1.9 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0009749 response to glucose(GO:0009749)
0.0 0.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 2.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0009615 response to virus(GO:0009615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0001534 radial spoke(GO:0001534)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 1.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.5 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004904 interferon receptor activity(GO:0004904)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 1.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0016496 substance P receptor activity(GO:0016496)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 2.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.0 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.9 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0015370 solute:sodium symporter activity(GO:0015370)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement