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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pax1a+pax1b_pax9

Z-value: 0.22

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Transcription factors associated with pax1a+pax1b_pax9

Gene Symbol Gene ID Gene Info
pax1a
ENSDARG00000008203 paired box 1a
pax1b
ENSDARG00000073814 paired box 1b
pax9
ENSDARG00000053829 paired box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax1bdr11_v1_chr20_-_48701593_48701593-0.823.5e-05Click!
pax9dr11_v1_chr17_-_38244117_382441170.781.2e-04Click!
pax1adr11_v1_chr17_+_42274240_422742400.635.5e-03Click!

Activity profile of pax1a+pax1b_pax9 motif

Sorted Z-values of pax1a+pax1b_pax9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_956821 0.50 ENSDART00000082101
ppp2r5ca
protein phosphatase 2, regulatory subunit B', gamma a
chr18_-_48550426 0.44 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr10_-_39154778 0.41 ENSDART00000186811
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr2_+_49864219 0.38 ENSDART00000187744
rpl37
ribosomal protein L37
chr21_+_13861589 0.33 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr24_+_41690545 0.31 ENSDART00000160069
lama1
laminin, alpha 1
chr17_+_996509 0.30 ENSDART00000158830
cyp1c2
cytochrome P450, family 1, subfamily C, polypeptide 2
chr20_-_31075972 0.29 ENSDART00000122927
si:ch211-198b3.4
si:ch211-198b3.4
chr12_-_7854216 0.29 ENSDART00000149594
ank3b
ankyrin 3b
chr5_-_35743741 0.23 ENSDART00000046157
ENSDART00000123562
ophn1
oligophrenin 1
chr14_+_23518110 0.23 ENSDART00000112930
si:ch211-221f10.2
si:ch211-221f10.2
chr2_+_19633493 0.21 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr1_-_46343999 0.15 ENSDART00000145117
ENSDART00000193233
atp11a
ATPase phospholipid transporting 11A
chr2_-_44282796 0.14 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr6_-_41079209 0.13 ENSDART00000151592
rab44
RAB44, member RAS oncogene family
chr3_-_50277959 0.12 ENSDART00000082773
ENSDART00000139524
arl16
ADP-ribosylation factor-like 16
chr1_+_12195700 0.12 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr12_-_18483348 0.11 ENSDART00000152757
tex2l
testis expressed 2, like
chr11_-_165288 0.11 ENSDART00000108703
ENSDART00000173151
tegt
testis enhanced gene transcript (BAX inhibitor 1)
chr2_-_44283554 0.10 ENSDART00000184684
mpz
myelin protein zero
chr20_+_12702923 0.10 ENSDART00000163499
zgc:153383
zgc:153383
chr3_+_47322494 0.09 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr5_+_39875646 0.09 ENSDART00000097608
si:ch73-138i16.1
si:ch73-138i16.1
chr11_+_37278457 0.09 ENSDART00000188946
creld1a
cysteine-rich with EGF-like domains 1a
chr6_-_31224563 0.08 ENSDART00000104616
lepr
leptin receptor
chr1_+_39553040 0.05 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr5_-_1047504 0.05 ENSDART00000159346
mbd2
methyl-CpG binding domain protein 2
chr10_-_39154594 0.04 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr16_+_20738740 0.03 ENSDART00000079343
jazf1b
JAZF zinc finger 1b
chr20_+_29587995 0.02 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr5_+_39936896 0.02 ENSDART00000135126
si:ch73-138i16.1
si:ch73-138i16.1
chr23_+_43255328 0.02 ENSDART00000102712
tgm2a
transglutaminase 2, C polypeptide A
chr13_-_24379271 0.01 ENSDART00000046360
rhoua
ras homolog family member Ua
chr25_+_6306885 0.01 ENSDART00000142705
ENSDART00000067510
crabp1a
cellular retinoic acid binding protein 1a
chr9_-_24031461 0.01 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr4_-_8902406 0.01 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr2_+_394166 0.00 ENSDART00000155733
mylk4a
myosin light chain kinase family, member 4a

Network of associatons between targets according to the STRING database.

First level regulatory network of pax1a+pax1b_pax9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0030719 P granule organization(GO:0030719)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions