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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr6a1a

Z-value: 0.66

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Transcription factors associated with nr6a1a

Gene Symbol Gene ID Gene Info
ENSDARG00000101508 nuclear receptor subfamily 6, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1adr11_v1_chr8_-_52909850_52909850-0.223.8e-01Click!

Activity profile of nr6a1a motif

Sorted Z-values of nr6a1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_29509133 1.99 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr3_-_3448095 1.95 ENSDART00000078886
si:dkey-46g23.5
chr2_-_50225411 1.87 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr24_-_9979342 1.68 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr24_-_9989634 1.62 ENSDART00000115275
zgc:152652
chr21_-_43636595 1.56 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
chr16_-_17197546 1.56 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr18_+_8912113 1.52 ENSDART00000147467
transmembrane protein 243, mitochondrial a
chr5_-_37103487 1.51 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr12_+_30788912 1.32 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr7_-_41013575 1.29 ENSDART00000150139
insulin induced gene 1
chr11_+_45287541 1.26 ENSDART00000165321
ENSDART00000173116
pyrroline-5-carboxylate reductase 1b
chr17_-_40956035 1.13 ENSDART00000124715
si:dkey-16j16.4
chr14_+_35414632 1.11 ENSDART00000191516
ENSDART00000084914
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr10_+_44719697 1.05 ENSDART00000158087
scavenger receptor class B, member 1
chr4_+_9478500 1.01 ENSDART00000030738
lipase maturation factor 2b
chr10_-_36793412 1.01 ENSDART00000185966
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr5_-_41124241 0.99 ENSDART00000083561
myotubularin related protein 12
chr11_+_14333441 0.97 ENSDART00000171969
polypyrimidine tract binding protein 1b
chr16_-_34195002 0.95 ENSDART00000054026
regulator of chromosome condensation 1
chr5_+_22579975 0.90 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr24_+_17334682 0.88 ENSDART00000018868
protein disulfide isomerase family A, member 4
chr5_+_9218318 0.86 ENSDART00000137774
si:ch211-12e13.1
chr11_+_45219558 0.86 ENSDART00000167828
transmembrane channel-like 6b
chr1_-_22652424 0.85 ENSDART00000036797
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_+_14512670 0.84 ENSDART00000161403
RAB3D, member RAS oncogene family, b
chr9_-_21238159 0.84 ENSDART00000146764
ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr22_-_22337382 0.83 ENSDART00000144684
si:ch211-129c21.1
chr22_+_25086942 0.82 ENSDART00000061117
ribosome binding protein 1b
chr25_+_17860962 0.81 ENSDART00000163153
parathyroid hormone 1a
chr21_+_35328025 0.81 ENSDART00000136211
arginyl-tRNA synthetase
chr25_+_7492663 0.81 ENSDART00000166496
catalase
chr1_-_8566567 0.79 ENSDART00000114613
pentatricopeptide repeat domain 1
chr9_-_12888082 0.78 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr2_+_32743807 0.78 ENSDART00000022909
kelch-like family member 18
chr22_+_25086567 0.77 ENSDART00000192114
ENSDART00000177284
ENSDART00000180296
ENSDART00000190384
ribosome binding protein 1b
chr11_+_24314148 0.76 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr14_+_26224731 0.75 ENSDART00000168673
GM2 ganglioside activator
chr5_-_11971946 0.73 ENSDART00000166285
si:ch73-47f2.1
chr5_+_50879545 0.71 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr5_+_31779911 0.71 ENSDART00000098163
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr9_-_21238616 0.71 ENSDART00000191840
ENSDART00000189127
COX17 cytochrome c oxidase copper chaperone
chr3_+_31662126 0.70 ENSDART00000113441
myosin, light chain kinase 5
chr1_+_24557414 0.69 ENSDART00000076519
dCTP pyrophosphatase 1
chr7_-_31618166 0.68 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr15_+_28410664 0.68 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr10_-_26218354 0.67 ENSDART00000180764
ADP-ribosylation factor interacting protein 2b
chr22_+_21152847 0.67 ENSDART00000007321
cytokine receptor-like factor 1b
chr10_-_16868211 0.65 ENSDART00000171755
stomatin (EPB72)-like 2
chr14_+_26224541 0.64 ENSDART00000128971
GM2 ganglioside activator
chr12_+_28955766 0.63 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr5_-_55201172 0.61 ENSDART00000134937
splicing regulatory glutamine/lysine-rich protein 1
chr3_-_13599482 0.61 ENSDART00000166639
Tu translation elongation factor, mitochondrial
chr22_+_21153031 0.60 ENSDART00000166342
cytokine receptor-like factor 1b
chr14_-_36412473 0.60 ENSDART00000128244
ENSDART00000138376
ankyrin repeat and SOCS box containing 5a
chr14_+_30272891 0.60 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr8_-_39859688 0.59 ENSDART00000019907
unc-119 homolog 1
chr8_-_54216499 0.58 ENSDART00000193678
methyl-CpG binding domain protein 4
chr8_-_26709959 0.58 ENSDART00000135215
transmembrane protein 51a
chr10_-_25543227 0.58 ENSDART00000007778
glutamate receptor, ionotropic, kainate 1a
chr25_-_35143360 0.56 ENSDART00000188033
zgc:165555
chr9_+_24095677 0.55 ENSDART00000150443
leucine rich repeat (in FLII) interacting protein 1a
chr23_-_545942 0.54 ENSDART00000105316
SAM domain and HD domain 1
chr10_+_33393829 0.54 ENSDART00000163458
ENSDART00000115379
zgc:153345
chr13_-_11763186 0.53 ENSDART00000102381
ENSDART00000187819
ubiquitin-conjugating enzyme E2D 3
chr7_+_25126629 0.53 ENSDART00000077217
zgc:101765
chr18_+_6706140 0.52 ENSDART00000111343
lipase maturation factor 2a
chr21_-_21178410 0.52 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr2_+_13694450 0.51 ENSDART00000077259
ENSDART00000189485
EBNA1 binding protein 2
chr21_+_1587722 0.50 ENSDART00000013581
WD repeat domain 91
chr9_-_10804796 0.50 ENSDART00000134911
si:ch1073-416j23.1
chr5_-_42180205 0.50 ENSDART00000145247
family with sequence similarity 222, member Ba
chr21_+_19319804 0.50 ENSDART00000063621
abraxas 2a, BRISC complex subunit
chr24_+_19542323 0.48 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr16_+_50741154 0.48 ENSDART00000101627
zgc:110372
chr24_-_10393969 0.48 ENSDART00000106260
ANKH inorganic pyrophosphate transport regulator a
chr23_+_12852655 0.48 ENSDART00000183015
structural maintenance of chromosomes 1A, like
chr5_+_31791001 0.48 ENSDART00000043010
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr12_-_999762 0.47 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
methyltransferase like 9
chr9_-_46276626 0.46 ENSDART00000165238
histone deacetylase 4
chr24_-_10828560 0.46 ENSDART00000132282
family with sequence similarity 49, member Bb
chr6_-_33924883 0.46 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr23_+_40139765 0.46 ENSDART00000185376
G protein signaling modulator 2, like
chr22_-_9861531 0.45 ENSDART00000193197
si:dkey-253d23.2
chr20_+_3277620 0.45 ENSDART00000067397
ENSDART00000135194
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr22_-_9860792 0.44 ENSDART00000155908
si:dkey-253d23.2
chr19_-_3724605 0.44 ENSDART00000123757
small integral membrane protein 13
chr9_-_7287375 0.44 ENSDART00000128352
MIT, microtubule interacting and transport, domain containing 1
chr9_+_24088062 0.43 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr18_-_20608300 0.43 ENSDART00000140632
BCL2 like 13
chr7_+_16033923 0.43 ENSDART00000161669
ENSDART00000114062
inner mitochondrial membrane peptidase subunit 1
chr20_-_28404362 0.43 ENSDART00000055932
ENSDART00000188161
phosphatidylinositol glycan anchor biosynthesis, class H
chr1_+_52633367 0.42 ENSDART00000134658
solute carrier family 44 (choline transporter), member 1a
chr1_+_52632856 0.42 ENSDART00000011725
solute carrier family 44 (choline transporter), member 1a
chr12_+_28956374 0.41 ENSDART00000033878
zinc finger protein 668
chr5_+_31959954 0.41 ENSDART00000142826
myosin IHb
chr13_+_21677767 0.41 ENSDART00000165166
mitochondrial ribosome-associated GTPase 1
chr10_+_7719796 0.41 ENSDART00000191795
gamma-glutamyl carboxylase
chr5_+_42124706 0.40 ENSDART00000020044
ENSDART00000156372
sedoheptulokinase
chr1_+_17527342 0.39 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
caspase 3, apoptosis-related cysteine peptidase a
chr1_-_55118745 0.39 ENSDART00000133915
SERTA domain containing 2a
chr17_+_6538733 0.39 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr24_+_30521619 0.38 ENSDART00000162903
dihydropyrimidine dehydrogenase a, tandem duplicate 3
chr2_+_58377395 0.38 ENSDART00000193511
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr20_-_23219964 0.38 ENSDART00000144933
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr20_+_23007470 0.38 ENSDART00000134639
ENSDART00000132916
si:ch73-249k16.4
chr24_+_34069675 0.37 ENSDART00000143995
si:ch211-190p8.2
chr14_-_25095808 0.37 ENSDART00000184244
matrin 3-like 1.1
chr2_+_30032303 0.37 ENSDART00000151841
RNA binding motif protein 33b
chr20_-_30931139 0.36 ENSDART00000006778
ENSDART00000146376
acetyl-CoA acetyltransferase 2
chr8_-_2153147 0.36 ENSDART00000124093
si:dkeyp-117b11.1
chr21_-_16087857 0.36 ENSDART00000144955
ENSDART00000180621
ENSDART00000135605
mitotic spindle organizing protein 2B
chr1_+_17527931 0.35 ENSDART00000131927
caspase 3, apoptosis-related cysteine peptidase a
chr6_-_29051773 0.35 ENSDART00000190508
ENSDART00000180191
ENSDART00000111682
ecotropic viral integration site 5b
chr20_+_4392687 0.35 ENSDART00000187271
im:7142702
chr21_+_15592426 0.35 ENSDART00000138207
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr6_-_11759860 0.35 ENSDART00000151296
si:ch211-162i14.1
chr10_+_11265387 0.35 ENSDART00000038888
hydroxysteroid dehydrogenase like 2
chr6_-_7686594 0.34 ENSDART00000091836
ENSDART00000151697
ubinuclein 2a
chr12_-_17152139 0.34 ENSDART00000152478
STAM binding protein-like 1
chr9_-_10805231 0.33 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
chr12_+_28888975 0.33 ENSDART00000076362
phosphorylase kinase, gamma 2 (testis)
chr11_+_15878343 0.33 ENSDART00000167191
ENSDART00000171862
ENSDART00000163992
ENSDART00000170065
pantothenate kinase 4
chr13_+_33368503 0.33 ENSDART00000139650
BRF1, RNA polymerase III transcription initiation factor a
chr15_+_32405959 0.32 ENSDART00000177269
si:ch211-162k9.6
chr15_-_30984804 0.32 ENSDART00000157005
neurofibromin 1a
chr23_-_35756115 0.32 ENSDART00000043429
junctophilin 2
chr13_+_2617555 0.32 ENSDART00000162208
phospholipid phosphatase 4
chr8_-_8489886 0.32 ENSDART00000183334
activator of basal transcription 1
chr24_-_25096199 0.31 ENSDART00000185076
pleckstrin homology-like domain, family B, member 2b
chr6_-_42949184 0.31 ENSDART00000147208
ER degradation enhancer, mannosidase alpha-like 1
chr10_-_36618674 0.31 ENSDART00000135302
remodeling and spacing factor 1b, tandem duplicate 1
chr7_+_20383841 0.30 ENSDART00000052906
si:dkey-33c9.6
chr16_+_25184207 0.29 ENSDART00000147584
hematopoietic cell signal transducer
chr5_-_35252761 0.29 ENSDART00000051278
transportin 1
chr18_-_226800 0.29 ENSDART00000165180
threonyl-tRNA synthetase-like 2
chr3_+_21189766 0.29 ENSDART00000078807
zgc:123295
chr20_-_39789846 0.29 ENSDART00000188418
ring finger protein 217
chr13_-_42724645 0.29 ENSDART00000046066
calpain 1, (mu/I) large subunit a
chr8_+_2878756 0.28 ENSDART00000168107
crumbs family member 2b
chr24_+_5789790 0.28 ENSDART00000189600

chr12_-_13650344 0.28 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
signal transducer and activator of transcription 5b
chr17_-_21162821 0.28 ENSDART00000157283
abhydrolase domain containing 12
chr5_-_69004007 0.28 ENSDART00000137443
ankyrin 1, erythrocytic a
chr2_-_20120904 0.27 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr21_+_43702016 0.27 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr1_+_57348756 0.26 ENSDART00000063750
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr15_+_2191900 0.26 ENSDART00000185913
arginine/serine-rich coiled-coil 1
chr21_+_15709061 0.26 ENSDART00000065772
D-dopachrome tautomerase
chr10_-_43117607 0.26 ENSDART00000148293
ENSDART00000089965
transmembrane protein 167A
chr14_+_6535426 0.26 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr11_+_26363435 0.25 ENSDART00000088800
phosphopantothenoylcysteine synthetase
chr10_+_8550435 0.25 ENSDART00000185664
TBC1 domain family, member 10Ab
chr8_+_16726386 0.25 ENSDART00000144621
small integral membrane protein 15
chr18_+_22220656 0.24 ENSDART00000191862
RHO family interacting cell polarization regulator 1
chr23_-_19953089 0.24 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr6_+_21536131 0.23 ENSDART00000113911
ENSDART00000188472
MICAL-like 1a
chr19_+_30884960 0.23 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
tyrosyl-tRNA synthetase
chr6_-_47246948 0.23 ENSDART00000162435
glutamate receptor, metabotropic 4
chr1_+_36911471 0.23 ENSDART00000148640
Rho GTPase activating protein 10
chr16_+_47428721 0.23 ENSDART00000180597
ENSDART00000032309
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr13_-_14926318 0.23 ENSDART00000142785
cell division cycle 25B
chr22_-_4407871 0.22 ENSDART00000162523
lysine (K)-specific demethylase 4B
chr23_+_16633951 0.22 ENSDART00000109537
ENSDART00000193323
syntaphilin b
chr22_+_31207226 0.21 ENSDART00000180016
glutamate receptor interacting protein 2b
chr6_+_6491013 0.21 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr14_-_35414559 0.21 ENSDART00000145033
ribonuclease H2, subunit C
chr2_-_56649883 0.21 ENSDART00000191786
glutathione peroxidase 4b
chr9_+_27379193 0.21 ENSDART00000142656
toll-like receptor 20, tandem duplicate 4
chr2_+_7818368 0.21 ENSDART00000007068
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_+_37110504 0.20 ENSDART00000132794
ENSDART00000042974
solute carrier family 1 (glutamate transporter), member 8b
chr7_+_17096281 0.20 ENSDART00000035558
HIV-1 Tat interactive protein 2
chr2_+_51028269 0.20 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr14_+_16034447 0.20 ENSDART00000161348
PRELI domain containing 1a
chr22_+_10163901 0.20 ENSDART00000190468
ribonuclease P/MRP 14 subunit
chr16_-_18960613 0.20 ENSDART00000183197
formin homology 2 domain containing 3b
chr3_-_10677890 0.20 ENSDART00000155382
ENSDART00000171319
si:ch1073-144j5.2
chr7_-_37917517 0.20 ENSDART00000173795
HEAT repeat containing 3
chr5_-_54792239 0.19 ENSDART00000056213
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_+_42338309 0.19 ENSDART00000015277
glutathione peroxidase 1b
chr3_-_584950 0.19 ENSDART00000164752
diverse immunoglobulin domain-containing protein 1.1
chr4_-_30362840 0.19 ENSDART00000165929
zinc finger protein 1083
chr11_-_44621405 0.19 ENSDART00000160639
tubulin folding cofactor E
chr8_-_20245892 0.19 ENSDART00000136911
alkaline ceramidase 1
chr20_-_33790003 0.18 ENSDART00000020183
family with sequence similarity 102, member B, b
chr3_-_5644028 0.18 ENSDART00000019957
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr3_+_58455428 0.18 ENSDART00000074129
zgc:171489
chr19_+_30885258 0.17 ENSDART00000143394
tyrosyl-tRNA synthetase
chr6_+_19383267 0.17 ENSDART00000166549
melanin-concentrating hormone receptor 1a
chr19_-_103289 0.17 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr4_+_77948517 0.17 ENSDART00000149305
protein kinase C and casein kinase substrate in neurons 2
chr21_+_20901505 0.17 ENSDART00000132741
complement component 7b
chr19_+_5134624 0.17 ENSDART00000151324
si:dkey-89b17.4
chr7_+_19482084 0.17 ENSDART00000173873
si:ch211-212k18.7
chr13_-_49666615 0.17 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr11_-_97817 0.16 ENSDART00000092903
engulfment and cell motility 2
chr21_-_33126697 0.16 ENSDART00000189293
ENSDART00000084559

chr2_-_5199431 0.16 ENSDART00000063384
prohibitin 2a
chr15_+_14854666 0.16 ENSDART00000163066
diablo, IAP-binding mitochondrial protein a
chr1_-_23110740 0.16 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 1.0 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 2.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.7 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2 0.7 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.2 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.5 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 1.9 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.8 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 0.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 0.8 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.7 GO:0006212 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860)
0.1 2.3 GO:0046688 response to copper ion(GO:0046688)
0.1 0.4 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.3 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.4 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.3 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.3 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.3 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.1 0.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 1.6 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.6 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.2 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0045299 otolith mineralization(GO:0045299)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.0 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 1.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.7 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.4 GO:0035060 brahma complex(GO:0035060)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.0 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 1.9 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 1.5 GO:0016531 copper chaperone activity(GO:0016531)
0.3 1.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 1.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.7 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.8 GO:0004096 catalase activity(GO:0004096)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0008106 alditol:NADP+ 1-oxidoreductase activity(GO:0004032) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.2 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 1.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 2.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway