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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr2f2

Z-value: 1.29

Motif logo

Transcription factors associated with nr2f2

Gene Symbol Gene ID Gene Info
ENSDARG00000040926 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f2dr11_v1_chr18_-_23874929_23874929-0.806.4e-05Click!

Activity profile of nr2f2 motif

Sorted Z-values of nr2f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_27564458 8.73 ENSDART00000123155
si:dkeyp-46h3.6
chr10_-_21542702 6.97 ENSDART00000146761
ENSDART00000134502
zgc:165539
chr10_+_19569052 6.27 ENSDART00000058425

chr19_-_27564980 5.43 ENSDART00000171967
si:dkeyp-46h3.8
chr1_+_24387659 5.22 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr17_-_2573021 5.20 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2595736 5.20 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2590222 5.17 ENSDART00000185711

chr17_-_2578026 5.05 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr23_+_2740741 4.82 ENSDART00000134938
zgc:114123
chr20_-_43741159 4.28 ENSDART00000192621
si:dkeyp-50f7.2
chr9_+_8380728 3.45 ENSDART00000133501
si:ch1073-75o15.4
chr9_+_33216945 3.39 ENSDART00000134029
si:ch211-125e6.12
chr17_-_2584423 3.36 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr7_-_24520866 3.34 ENSDART00000077039
fatty acid amide hydrolase 2b
chr18_-_43866526 2.64 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr12_-_10508952 2.42 ENSDART00000152806
zgc:152977
chr22_-_24992532 2.40 ENSDART00000102751
si:dkey-179j5.5
chr19_-_3056235 1.99 ENSDART00000137020
block of proliferation 1
chr22_-_7050 1.87 ENSDART00000127829
ATPase family, AAA domain containing 3
chr15_-_30857350 1.86 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr9_-_41153896 1.78 ENSDART00000059667
WD repeat domain 75
chr11_+_41838801 1.72 ENSDART00000014871
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr18_-_43866001 1.69 ENSDART00000150218
trehalase (brush-border membrane glycoprotein)
chr7_-_20611039 1.65 ENSDART00000170422
si:dkey-19b23.8
chr3_-_36419641 1.63 ENSDART00000173545
component of oligomeric golgi complex 1
chr7_+_24520518 1.52 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr9_+_22782027 1.49 ENSDART00000090816
replication timing regulatory factor 1
chr20_+_36806398 1.49 ENSDART00000153317
ABRA C-terminal like
chr16_-_39131666 1.44 ENSDART00000075517
growth differentiation factor 6a
chr5_+_9218318 1.44 ENSDART00000137774
si:ch211-12e13.1
chr18_+_1615 1.43 ENSDART00000082450
homer scaffolding protein 2
chr8_+_21159122 1.41 ENSDART00000033491
SPRY domain containing 4
chr1_-_53468160 1.41 ENSDART00000143349
zgc:66455
chr16_-_25233515 1.40 ENSDART00000058943
zgc:110182
chr6_+_40952031 1.36 ENSDART00000189219
POZ (BTB) and AT hook containing zinc finger 1
chr25_-_35143360 1.36 ENSDART00000188033
zgc:165555
chr7_-_51775688 1.32 ENSDART00000149793
bone morphogenetic protein 15
chr10_+_43039947 1.31 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr7_+_24114694 1.31 ENSDART00000127177
mitochondrial ribosomal protein L52
chr3_+_31662126 1.25 ENSDART00000113441
myosin, light chain kinase 5
chr23_+_30730121 1.23 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr7_+_24115082 1.21 ENSDART00000182718
mitochondrial ribosomal protein L52
chr18_-_127558 1.19 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr13_+_8696825 1.15 ENSDART00000109059
tetratricopeptide repeat domain 7A
chr18_+_36664654 1.14 ENSDART00000128707
ENSDART00000098972
calpain 12
chr3_-_34561624 1.13 ENSDART00000129313
septin 9a
chr3_-_5829501 1.12 ENSDART00000091017
protein kinase N1b
chr24_-_21172122 1.10 ENSDART00000154259
ATPase H+ transporting V1 subunit Ab
chr4_-_19693978 1.09 ENSDART00000100974
ENSDART00000040405
staphylococcal nuclease and tudor domain containing 1
chr17_-_49407091 1.05 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr14_+_36414856 1.04 ENSDART00000123343
ENSDART00000015761
nei-like DNA glycosylase 3
chr17_-_6613458 1.00 ENSDART00000175024
si:ch211-189e2.3
chr15_+_8394819 0.99 ENSDART00000147086
transmembrane protein 160
chr18_-_46183462 0.99 ENSDART00000021192
potassium channel, subfamily K, member 6
chr24_-_27409599 0.99 ENSDART00000041770
chemokine (C-C motif) ligand 34b, duplicate 3
chr2_-_20120904 0.97 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr25_-_24202576 0.95 ENSDART00000048507
UEV and lactate/malate dehyrogenase domains
chr18_-_158541 0.92 ENSDART00000188914
ENSDART00000191052
transient receptor potential cation channel, subfamily M, member 7
chr14_-_32876280 0.92 ENSDART00000173168
si:rp71-46j2.7
chr3_+_34121156 0.91 ENSDART00000174929
aldehyde dehydrogenase 3 family, member B1
chr2_-_389867 0.90 ENSDART00000004848
Werner helicase interacting protein 1
chr6_-_31682135 0.89 ENSDART00000153988
cache domain containing 1
chr20_-_51656512 0.88 ENSDART00000129965

chr21_-_9446747 0.88 ENSDART00000158790
protein tyrosine phosphatase, non-receptor type 13
chr3_+_17933132 0.86 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
2',3'-cyclic nucleotide 3' phosphodiesterase
chr10_+_35417099 0.85 ENSDART00000063398
HERV-H LTR-associating 2a, tandem duplicate 1
chr7_-_58244220 0.85 ENSDART00000180450
un-named hu7910
chr9_-_25255490 0.85 ENSDART00000141502
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr16_-_25680666 0.83 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_20464133 0.81 ENSDART00000078192
canopy4
chr10_+_15340768 0.81 ENSDART00000046274
ENSDART00000168909
trafficking protein particle complex 13
chr2_-_56649883 0.79 ENSDART00000191786
glutathione peroxidase 4b
chr6_-_11759860 0.79 ENSDART00000151296
si:ch211-162i14.1
chr5_+_43470544 0.78 ENSDART00000111587
Rho-related BTB domain containing 2a
chr10_+_45128375 0.78 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr7_-_62003831 0.78 ENSDART00000113585
ENSDART00000062704
phospholipase A2-activating protein
chr10_-_22797959 0.77 ENSDART00000183269
procollagen C-endopeptidase enhancer a
chr3_+_12755535 0.74 ENSDART00000161286
cytochrome P450, family 2, subfamily K, polypeptide17
chr1_+_1712140 0.74 ENSDART00000081047
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1
chr4_-_9579299 0.73 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr14_+_30413312 0.72 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr10_+_24690534 0.72 ENSDART00000079549
transmembrane phosphatase with tensin homology
chr4_-_858434 0.72 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr6_-_28117995 0.72 ENSDART00000147253
si:ch73-194h10.3
chr17_-_6076266 0.72 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr25_-_20049449 0.71 ENSDART00000104315
zgc:136858
chr2_-_38312757 0.71 ENSDART00000167274
adaptor-related protein complex 1, gamma 2 subunit
chr16_-_19568388 0.70 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr10_+_1849874 0.70 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr19_-_11031145 0.70 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tropomyosin 3
chr3_+_34180835 0.67 ENSDART00000055252
translocase of inner mitochondrial membrane 29
chr13_+_39277178 0.66 ENSDART00000113259
si:dkey-85a20.4
chr17_-_6076084 0.65 ENSDART00000058890
epoxide hydrolase 2, cytoplasmic
chr23_-_18595020 0.65 ENSDART00000187032
ENSDART00000191047
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr20_+_3277620 0.65 ENSDART00000067397
ENSDART00000135194
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr2_+_58377395 0.65 ENSDART00000193511
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr3_+_39566999 0.65 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr25_+_36348401 0.64 ENSDART00000103006
histone cluster 1 H2A family member 3
chr10_+_20364009 0.64 ENSDART00000186139
ENSDART00000080395
golgin A7
chr3_+_26288981 0.62 ENSDART00000163500
ras homolog family member T1a
chr9_+_41690153 0.61 ENSDART00000100226
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr11_-_127785 0.61 ENSDART00000162658
ADP ribosylation factor GTPase activating protein 1
chr24_-_23716097 0.61 ENSDART00000084954
ENSDART00000129028
phosphatidylinositol glycan anchor biosynthesis, class N
chr2_-_3614005 0.59 ENSDART00000110399
phosphotriesterase related
chr9_+_54695981 0.59 ENSDART00000183605
RAB9A, member RAS oncogene family
chr16_+_4078240 0.58 ENSDART00000160890
inositol polyphosphate-5-phosphatase B
chr17_-_22137199 0.57 ENSDART00000089689
mitochondrial ribosomal protein S5
chr8_-_8349653 0.57 ENSDART00000025214
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr6_-_1587291 0.57 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr16_+_33143503 0.57 ENSDART00000058471
ENSDART00000179385
rhomboid, veinlet-like 2 (Drosophila)
chr14_+_23874062 0.56 ENSDART00000172149
SH3 domain containing ring finger 2
chr15_+_40074923 0.56 ENSDART00000111018
neuronal guanine nucleotide exchange factor
chr12_+_1609563 0.56 ENSDART00000163559
solute carrier family 39 member 11
chr23_-_44786844 0.56 ENSDART00000148669
si:ch73-269m23.5
chr22_-_31517300 0.55 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr14_-_30876299 0.55 ENSDART00000180305
ubiquitin-like 3b
chr7_-_19600181 0.55 ENSDART00000100757
oxidase (cytochrome c) assembly 1-like
chr25_+_22017182 0.55 ENSDART00000156517
si:dkey-217l24.1
chr12_+_6195191 0.55 ENSDART00000043236
ENSDART00000186420
protein kinase, cGMP-dependent, type Ib
chr9_-_28990649 0.54 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr2_+_9821757 0.54 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr22_+_2417105 0.53 ENSDART00000106415
zgc:113220
chr9_+_21151138 0.52 ENSDART00000133903
hydroxyacid oxidase 2 (long chain)
chr25_+_19008497 0.52 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr16_-_27149202 0.51 ENSDART00000179726
transmembrane protein 245
chr7_+_24496894 0.51 ENSDART00000149994
negative elongation factor complex member A
chr23_-_18567088 0.50 ENSDART00000192371
selenophosphate synthetase 2
chr3_+_24050043 0.50 ENSDART00000151788
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr9_-_4606463 0.48 ENSDART00000179110
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr5_-_61588998 0.48 ENSDART00000050912
peroxisomal biogenesis factor 12
chr16_+_7991274 0.48 ENSDART00000179704
anoctamin 10a
chr16_-_32672883 0.48 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
PNN-interacting serine/arginine-rich protein
chr17_+_26718648 0.48 ENSDART00000154492
NRDE-2, necessary for RNA interference, domain containing
chr2_-_41571454 0.47 ENSDART00000022643
zinc finger protein 622
chr18_+_27515640 0.47 ENSDART00000181593
tumor protein p53 inducible protein 11b
chr15_+_47618221 0.47 ENSDART00000168722
PAF1 homolog, Paf1/RNA polymerase II complex component
chr12_+_48972915 0.46 ENSDART00000170695
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b
chr21_+_41743493 0.46 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr8_-_22542467 0.46 ENSDART00000182588
ENSDART00000134542
cold shock domain containing E1, RNA-binding
chr8_-_20243389 0.45 ENSDART00000184904
alkaline ceramidase 1
chr4_+_1619584 0.45 ENSDART00000148486
SR-related CTD-associated factor 11
chr3_+_31680592 0.45 ENSDART00000172456
myosin, light chain kinase 5
chr21_-_1640547 0.45 ENSDART00000151041
zgc:152948
chr17_+_48314724 0.45 ENSDART00000125617
SPARC related modular calcium binding 1
chr16_-_19568795 0.44 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr18_-_12957451 0.43 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr23_+_9522942 0.43 ENSDART00000137751
oxysterol binding protein-like 2b
chr9_+_17429170 0.43 ENSDART00000006256
zgc:101559
chr9_-_9960940 0.43 ENSDART00000092164
protein arginine methyltransferase 2
chr3_+_40289418 0.43 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr13_+_24552254 0.43 ENSDART00000147907
lectin, galactoside-binding-like b
chr24_+_39137001 0.43 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
TBC1 domain family, member 24
chr1_-_57172294 0.42 ENSDART00000063774
Rac family small GTPase 1, like
chr2_+_5948534 0.42 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr6_+_55819038 0.42 ENSDART00000108786
si:ch211-81n22.1
chr16_-_21692024 0.41 ENSDART00000123597
si:ch211-154o6.2
chr17_+_15534815 0.40 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr21_+_7188943 0.40 ENSDART00000172174
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr22_+_30502555 0.40 ENSDART00000139128
ENSDART00000104747
zgc:171679
chr22_-_11833317 0.39 ENSDART00000125423
ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr20_-_27733683 0.39 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr7_+_65398161 0.39 ENSDART00000166109
ENSDART00000157399
ubiquitin specific peptidase 47
chr17_+_15213496 0.39 ENSDART00000058351
ENSDART00000131663
glucosamine-phosphate N-acetyltransferase 1
chr13_-_42724645 0.39 ENSDART00000046066
calpain 1, (mu/I) large subunit a
chr5_+_63340637 0.39 ENSDART00000143742
si:ch73-376l24.4
chr4_+_25917915 0.39 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr17_+_33418475 0.39 ENSDART00000169145
synaptosomal-associated protein 23.1
chr11_-_5563498 0.38 ENSDART00000160835
peroxisomal biogenesis factor 11 gamma
chr13_-_33114933 0.38 ENSDART00000140543
ENSDART00000075953
zinc finger, FYVE domain containing 26
chr5_+_4016271 0.37 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
gametogenetin binding protein 2
chr23_+_9522781 0.37 ENSDART00000136486
oxysterol binding protein-like 2b
chr6_-_14004772 0.37 ENSDART00000185629
zgc:92027
chr5_+_63322093 0.35 ENSDART00000158086
si:ch73-376l24.3
chr2_+_30531726 0.35 ENSDART00000146518
ankyrin repeat domain 33Bb
chr10_-_11385155 0.35 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr11_-_44999858 0.34 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr13_-_41546779 0.34 ENSDART00000163331
protocadherin-related 15a
chr4_-_75172216 0.34 ENSDART00000127522
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr13_-_9311253 0.34 ENSDART00000058056
mitochondrial ribosomal protein S26
chr9_+_54984537 0.33 ENSDART00000029528
motile sperm domain containing 2
chr14_+_22680485 0.33 ENSDART00000167829
GDNF family receptor alpha 4b
chr20_-_9658405 0.33 ENSDART00000023809
nidogen 2b (osteonidogen)
chr15_+_17345609 0.33 ENSDART00000111753
vacuole membrane protein 1
chr18_+_25546227 0.32 ENSDART00000085824
peroxisomal biogenesis factor 11 alpha
chr14_+_22152060 0.32 ENSDART00000082697
ENSDART00000054982
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr18_+_31410652 0.31 ENSDART00000098504
differentially expressed in FDCP 8 homolog (mouse)
chr22_-_10774735 0.31 ENSDART00000081156
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr14_+_989733 0.31 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr1_-_19215336 0.31 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr12_+_30368145 0.31 ENSDART00000153454
si:ch211-225b10.4
chr22_-_26595027 0.31 ENSDART00000184162

chr5_-_32396929 0.30 ENSDART00000023977
F-box and WD repeat domain containing 2
chr12_+_26670778 0.29 ENSDART00000144355
Rho GTPase activating protein 12b
chr19_-_340347 0.29 ENSDART00000139924
golgi phosphoprotein 3-like
chr19_+_48024457 0.28 ENSDART00000163823
karyopherin (importin) beta 1
chr13_-_3516473 0.28 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr23_-_46126444 0.28 ENSDART00000030004

chr4_-_36139585 0.27 ENSDART00000132071
zinc finger protein 992
chr11_+_6115621 0.27 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0005991 trehalose metabolic process(GO:0005991)
1.1 18.8 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 2.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 4.8 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.5 5.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.4 1.1 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.4 1.4 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 1.3 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 1.0 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.4 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 0.7 GO:1905067 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.2 0.5 GO:0090151 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.2 0.9 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.7 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.7 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.6 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 2.5 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.0 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.4 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.4 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0043111 replication fork arrest(GO:0043111)
0.0 0.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.9 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0072679 thymocyte migration(GO:0072679)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.6 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 1.0 GO:0006284 base-excision repair(GO:0006284)
0.0 0.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.4 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 1.5 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 2.0 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 1.3 GO:0006497 protein lipidation(GO:0006497)
0.0 0.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 1.5 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.0 0.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.9 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 0.0 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.8 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 1.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.0 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 1.9 GO:0006364 rRNA processing(GO:0006364)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.1 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0048798 somatic muscle development(GO:0007525) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0070545 PeBoW complex(GO:0070545)
0.3 0.8 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 0.7 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 1.2 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 2.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.5 GO:0098799 mitochondrial sorting and assembly machinery complex(GO:0001401) outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 11.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 5.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 18.8 GO:0035804 structural constituent of egg coat(GO:0035804)
1.4 4.3 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
1.3 5.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.5 1.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 1.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.3 0.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.9 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 2.4 GO:0043495 protein anchor(GO:0043495)
0.2 1.0 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2 1.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 2.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.1 0.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.1 0.9 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 20.7 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 1.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.2 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 1.0 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.9 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 2.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 1.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins