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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for nr2f2
Z-value: 1.29
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Transcription factors associated with nr2f2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| nr2f2 | dr11_v1_chr18_-_23874929_23874929 | -0.80 | 6.4e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_27564458 Show fit | 8.73 |
ENSDART00000123155
|
si:dkeyp-46h3.6 |
|
| chr10_-_21542702 Show fit | 6.97 |
ENSDART00000146761
ENSDART00000134502 |
zgc:165539 |
|
| chr10_+_19569052 Show fit | 6.27 |
ENSDART00000058425
|
|
|
| chr19_-_27564980 Show fit | 5.43 |
ENSDART00000171967
|
si:dkeyp-46h3.8 |
|
| chr1_+_24387659 Show fit | 5.22 |
ENSDART00000130356
|
quinoid dihydropteridine reductase b2 |
|
| chr17_-_2573021 Show fit | 5.20 |
ENSDART00000074181
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2595736 Show fit | 5.20 |
ENSDART00000128797
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2590222 Show fit | 5.17 |
ENSDART00000185711
|
|
|
| chr17_-_2578026 Show fit | 5.05 |
ENSDART00000065821
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr23_+_2740741 Show fit | 4.82 |
ENSDART00000134938
|
zgc:114123 |
Network of associatons between targets according to the STRING database.
First level regulatory network of nr2f2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 18.8 | GO:0035803 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.5 | 5.2 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.6 | 4.8 | GO:0033206 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) |
| 1.4 | 4.3 | GO:0005991 | trehalose metabolic process(GO:0005991) |
| 0.1 | 2.5 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.1 | 2.4 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.7 | 2.1 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.1 | 2.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 2.0 | GO:0031047 | gene silencing by RNA(GO:0031047) |
| 0.1 | 1.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.9 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 5.9 | GO:0005938 | cell cortex(GO:0005938) |
| 0.1 | 2.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 2.4 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.7 | 2.0 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.1 | 1.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 1.6 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 1.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.2 | 1.2 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.1 | 1.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.7 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 1.7 | 18.8 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 1.3 | 5.2 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404) |
| 1.4 | 4.3 | GO:0015927 | alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927) |
| 0.2 | 2.4 | GO:0043495 | protein anchor(GO:0043495) |
| 0.2 | 2.1 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 2.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 2.0 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 1.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 1.7 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 0.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.4 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 1.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.1 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.2 | 1.0 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 0.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 0.7 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 0.7 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 0.6 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |