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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for nr2e1
Z-value: 0.90
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Transcription factors associated with nr2e1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| nr2e1 | dr11_v1_chr20_-_32446406_32446406 | 0.80 | 6.6e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_14272083 Show fit | 2.93 |
ENSDART00000169986
|
Tctex1 domain containing 1 |
|
| chr12_+_18533198 Show fit | 2.54 |
ENSDART00000189729
|
meiosis specific with OB domains |
|
| chr25_-_12515741 Show fit | 2.44 |
ENSDART00000159487
|
si:ch211-280a23.2 |
|
| chr2_-_14271874 Show fit | 2.38 |
ENSDART00000189390
|
Tctex1 domain containing 1 |
|
| chr23_+_3731375 Show fit | 2.36 |
ENSDART00000141782
|
small integral membrane protein 29 |
|
| chr18_+_31016379 Show fit | 2.35 |
ENSDART00000172461
ENSDART00000163471 |
urate (5-hydroxyiso-) hydrolase a |
|
| chr18_-_41232297 Show fit | 2.28 |
ENSDART00000036928
|
F-box protein 36a |
|
| chr7_-_30367650 Show fit | 2.27 |
ENSDART00000075519
|
aldehyde dehydrogenase 1 family, member A2 |
|
| chr14_-_858985 Show fit | 2.25 |
ENSDART00000148687
ENSDART00000149375 |
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a |
|
| chr4_-_73709502 Show fit | 2.21 |
ENSDART00000170308
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of nr2e1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.7 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 0.1 | 2.8 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
| 0.1 | 2.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.8 | 2.4 | GO:0046415 | urate catabolic process(GO:0019628) urate metabolic process(GO:0046415) |
| 0.6 | 2.3 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.4 | 2.3 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.3 | 2.0 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) |
| 0.0 | 1.4 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.4 | 1.3 | GO:0043576 | respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576) |
| 0.1 | 1.3 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.3 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 1.6 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 1.4 | GO:0097546 | ciliary base(GO:0097546) |
| 0.2 | 1.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 1.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 1.0 | GO:1902711 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.4 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.4 | GO:0034707 | chloride channel complex(GO:0034707) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.8 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.2 | 3.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.6 | 2.5 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.4 | 2.3 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.2 | 2.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.2 | 2.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 1.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.4 | 1.6 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.0 | 1.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 1.3 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.5 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.9 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 0.7 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.4 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.4 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 0.4 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 0.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |