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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr2c1

Z-value: 0.41

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Transcription factors associated with nr2c1

Gene Symbol Gene ID Gene Info
ENSDARG00000045527 nuclear receptor subfamily 2, group C, member 1
ENSDARG00000111803 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c1dr11_v1_chr4_-_25859305_25859305-0.175.0e-01Click!

Activity profile of nr2c1 motif

Sorted Z-values of nr2c1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_154556 1.97 ENSDART00000193153
zinc finger, GATA-like protein 1
chr10_-_21362071 1.61 ENSDART00000125167
avidin
chr19_-_8798178 1.57 ENSDART00000188232
ceramide synthase 2a
chr3_+_27770110 1.03 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr3_-_34724879 0.80 ENSDART00000177021
thyroid hormone receptor alpha a
chr10_+_15340768 0.78 ENSDART00000046274
ENSDART00000168909
trafficking protein particle complex 13
chr1_+_24387659 0.76 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr18_-_158541 0.73 ENSDART00000188914
ENSDART00000191052
transient receptor potential cation channel, subfamily M, member 7
chr3_-_34561624 0.72 ENSDART00000129313
septin 9a
chr18_+_27515640 0.71 ENSDART00000181593
tumor protein p53 inducible protein 11b
chr19_-_27564458 0.71 ENSDART00000123155
si:dkeyp-46h3.6
chr16_+_30002605 0.68 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr21_+_1119046 0.65 ENSDART00000184678

chr19_-_27564980 0.64 ENSDART00000171967
si:dkeyp-46h3.8
chr20_-_36671660 0.63 ENSDART00000134819
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr8_+_21159122 0.59 ENSDART00000033491
SPRY domain containing 4
chr17_-_49407091 0.58 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr11_+_24313931 0.58 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr12_+_31783066 0.57 ENSDART00000105584
leucine rich repeat containing 59
chr3_+_34159192 0.56 ENSDART00000151119
coactivator-associated arginine methyltransferase 1
chr3_+_54047342 0.55 ENSDART00000178486
olfactomedin 2a
chr2_-_15040345 0.55 ENSDART00000109657
si:dkey-10f21.4
chr19_-_47571456 0.53 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr5_+_29851433 0.52 ENSDART00000143434
ubiquitin associated and SH3 domain containing Ba
chr11_+_3499111 0.52 ENSDART00000113096
ENSDART00000171621
pseudouridylate synthase-like 1
chr13_+_7575563 0.51 ENSDART00000146592
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr4_-_7875808 0.50 ENSDART00000162276
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr12_+_48681601 0.49 ENSDART00000187831
uroporphyrinogen III synthase
chr6_+_40952031 0.49 ENSDART00000189219
POZ (BTB) and AT hook containing zinc finger 1
chr17_-_6613458 0.48 ENSDART00000175024
si:ch211-189e2.3
chr12_+_23866368 0.48 ENSDART00000188652
ENSDART00000192478
supervillin a
chr1_-_19215336 0.48 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr11_+_24314148 0.48 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr16_-_25680666 0.47 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr13_+_7241170 0.46 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr23_+_37482727 0.46 ENSDART00000162737
agmatine ureohydrolase (agmatinase)
chr6_-_39903393 0.46 ENSDART00000085945
Ts translation elongation factor, mitochondrial
chr8_+_10862353 0.46 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr24_+_39137001 0.46 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
TBC1 domain family, member 24
chr20_+_36806398 0.45 ENSDART00000153317
ABRA C-terminal like
chr2_-_57076687 0.45 ENSDART00000161523
solute carrier family 25, member 42
chr12_+_19138452 0.45 ENSDART00000141346
ENSDART00000066397
PHD finger protein 5A
chr2_-_4787566 0.45 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr13_-_36566260 0.45 ENSDART00000030133
synaptojanin 2 binding protein
chr18_+_38807239 0.44 ENSDART00000184332
family with sequence similarity 214, member A
chr6_+_40523370 0.43 ENSDART00000033819
protein kinase C, delta a
chr21_+_15883546 0.43 ENSDART00000186325
family with sequence similarity 169, member Ab
chr5_+_57328535 0.42 ENSDART00000149646
solute carrier family 31 (copper transporter), member 1
chr3_+_26035550 0.42 ENSDART00000078137
ankyrin repeat domain 54
chr14_+_1719367 0.42 ENSDART00000157696
transient receptor potential cation channel, subfamily C, member 7b
chr22_-_7050 0.41 ENSDART00000127829
ATPase family, AAA domain containing 3
chr10_-_40939706 0.41 ENSDART00000059795
ENSDART00000190510
bone morphogenetic protein 1b
chr23_+_39346774 0.41 ENSDART00000190985
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_+_30413312 0.40 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr21_+_13245302 0.40 ENSDART00000189498
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr14_+_989733 0.40 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr20_-_29499363 0.39 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr15_-_28618502 0.39 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr10_+_36441124 0.38 ENSDART00000185626
ubiquitin specific peptidase like 1
chr3_-_36419641 0.38 ENSDART00000173545
component of oligomeric golgi complex 1
chr7_-_42206720 0.37 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr8_+_2530065 0.36 ENSDART00000063943
mitochondrial ribosomal protein L40
chr10_-_40939303 0.36 ENSDART00000134295
bone morphogenetic protein 1b
chr23_+_2914577 0.36 ENSDART00000184897
zgc:158828
chr1_+_54737353 0.35 ENSDART00000130675
ENSDART00000162075
phosphatidylinositol 4-kinase type 2 alpha
chr25_+_22017182 0.35 ENSDART00000156517
si:dkey-217l24.1
chr21_+_38089036 0.34 ENSDART00000147219
Kruppel-like factor 8
chr3_+_31680592 0.33 ENSDART00000172456
myosin, light chain kinase 5
chr3_+_19336286 0.33 ENSDART00000111528
KRI1 homolog
chr23_+_39346930 0.33 ENSDART00000102843
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr16_-_39131666 0.33 ENSDART00000075517
growth differentiation factor 6a
chr18_+_43183749 0.32 ENSDART00000151166
nectin cell adhesion molecule 1b
chr4_-_2975461 0.31 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr23_+_33963619 0.31 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr22_-_14262115 0.31 ENSDART00000168264
si:ch211-246m6.5
chr17_+_654759 0.30 ENSDART00000193703

chr15_+_21711671 0.30 ENSDART00000136151
zgc:162339
chr3_-_18805225 0.30 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr10_-_38443312 0.30 ENSDART00000141260
glycerophosphodiester phosphodiesterase domain containing 5a
chr7_+_42206847 0.29 ENSDART00000149250
phosphorylase kinase, beta
chr19_-_24136233 0.29 ENSDART00000143365
THAP domain containing 7
chr23_+_39970425 0.29 ENSDART00000165376
FYVE and coiled-coil domain containing 1a
chr1_-_51720633 0.29 ENSDART00000045894
ribonuclease H2, subunit A
chr25_+_12012 0.28 ENSDART00000170348
contactin 1a
chr23_+_4583747 0.28 ENSDART00000160350

chr18_+_1615 0.28 ENSDART00000082450
homer scaffolding protein 2
chr1_-_44581937 0.27 ENSDART00000009858
thioredoxin-related transmembrane protein 2b
chr3_+_40289418 0.26 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr23_+_22597624 0.25 ENSDART00000054337
G protein-coupled receptor 157
chr7_-_30553588 0.25 ENSDART00000139546
SAFB-like, transcription modulator
chr24_+_39641991 0.24 ENSDART00000142182
LUC7-like (S. cerevisiae)
chr10_-_8197049 0.23 ENSDART00000129467
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr24_+_14240196 0.23 ENSDART00000124740
nuclear receptor coactivator 2
chr15_-_31213119 0.22 ENSDART00000182009
CUE domain containing 1b
chr6_-_51541488 0.21 ENSDART00000156336
si:dkey-6e2.2
chr9_+_38502524 0.20 ENSDART00000087229
leishmanolysin-like (metallopeptidase M8 family)
chr25_-_35113891 0.20 ENSDART00000190724
zgc:165555
chr5_+_31049742 0.19 ENSDART00000173097
zinc finger, ZZ-type with EF hand domain 1
chr10_-_41400049 0.19 ENSDART00000009838
glycerol-3-phosphate acyltransferase 4
chr9_+_38503233 0.18 ENSDART00000140331
leishmanolysin-like (metallopeptidase M8 family)
chr20_-_32981053 0.17 ENSDART00000138708
neuroblastoma amplified sequence
chr3_-_58455289 0.16 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr3_+_1179601 0.16 ENSDART00000173378
TRIO and F-actin binding protein b
chr9_+_21151138 0.16 ENSDART00000133903
hydroxyacid oxidase 2 (long chain)
chr11_-_36020005 0.15 ENSDART00000031993
inositol 1,4,5-trisphosphate receptor, type 1b
chr5_+_24156170 0.15 ENSDART00000136570
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr10_+_9561066 0.14 ENSDART00000136281
si:ch211-243g18.2
chr20_-_874807 0.14 ENSDART00000020506
sorting nexin 14
chr24_-_29586082 0.14 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr13_-_30143127 0.13 ENSDART00000146097
trypsin domain containing 1
chr6_-_39893501 0.13 ENSDART00000141611
ENSDART00000135631
ENSDART00000077662
ENSDART00000130613
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr7_+_34296789 0.13 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr23_-_46126444 0.13 ENSDART00000030004

chr2_+_6067371 0.12 ENSDART00000053868
ENSDART00000145244
aldehyde dehydrogenase 9 family, member A1b
chr10_+_35417099 0.12 ENSDART00000063398
HERV-H LTR-associating 2a, tandem duplicate 1
chr8_+_32742650 0.12 ENSDART00000138117
hemicentin 2
chr1_-_53750522 0.12 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr1_-_44314 0.12 ENSDART00000160050
transmembrane protein 39A
chr25_+_27410352 0.12 ENSDART00000154362
protection of telomeres 1 homolog
chr10_+_589501 0.12 ENSDART00000188415

chr7_-_46744080 0.12 ENSDART00000193328
teashirt zinc finger homeobox 3b
chr21_+_43171013 0.11 ENSDART00000151362
zinc finger, CCHC domain containing 10
chr2_-_56649883 0.11 ENSDART00000191786
glutathione peroxidase 4b
chr19_-_25519612 0.11 ENSDART00000133150
si:dkey-202e17.1
chr9_+_34433053 0.10 ENSDART00000137416
si:ch211-269e2.1
chr17_+_52524452 0.10 ENSDART00000016614
dihydrolipoamide S-succinyltransferase
chr22_+_17399124 0.09 ENSDART00000145769
RAB GTPase activating protein 1-like
chr12_+_26670778 0.09 ENSDART00000144355
Rho GTPase activating protein 12b
chr1_+_44582369 0.09 ENSDART00000003022
ENSDART00000137980
mediator complex subunit 19b
chr2_-_13382726 0.09 ENSDART00000017787
neuromedin U receptor 1b
chr15_+_47386939 0.09 ENSDART00000128224

chr18_-_43866526 0.08 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr15_-_1844048 0.08 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr22_-_7129631 0.07 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr23_+_45611980 0.07 ENSDART00000181582
doublecortin-like kinase 2b
chr21_-_45728069 0.07 ENSDART00000185101

chr5_-_68927728 0.07 ENSDART00000132838
ankyrin 1, erythrocytic a
chr10_-_43404027 0.07 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr5_-_26330313 0.07 ENSDART00000148656
ARVCF, delta catenin family member b
chr1_+_58303892 0.07 ENSDART00000147678

chr23_+_27912079 0.07 ENSDART00000171859

chr16_-_560574 0.06 ENSDART00000148452
iroquois homeobox 2a
chr8_-_4097722 0.06 ENSDART00000135006
cut-like homeobox 2b
chr21_-_1972236 0.06 ENSDART00000192858
ENSDART00000189962
ENSDART00000182461
ENSDART00000165547
WD repeat domain 7
chr9_+_24936496 0.06 ENSDART00000157474
solute carrier family 39 (zinc transporter), member 10
chr10_-_29900546 0.06 ENSDART00000147441
lens intrinsic membrane protein 2.1
chr1_-_46859398 0.06 ENSDART00000135795
1-acylglycerol-3-phosphate O-acyltransferase 3
chr17_-_47305034 0.05 ENSDART00000150116
ALK receptor tyrosine kinase
chr19_-_5369486 0.05 ENSDART00000105004
keratin 17
chr19_-_3193443 0.05 ENSDART00000179855
si:ch211-133n4.6
chr8_+_8699085 0.05 ENSDART00000021209
ubiquitously-expressed, prefoldin-like chaperone
chr6_-_42112191 0.05 ENSDART00000085472
glutamate receptor, metabotropic 2a
chr1_+_58442694 0.05 ENSDART00000160897
zgc:194906
chr12_-_44199316 0.05 ENSDART00000170378
si:ch73-329n5.1
chr17_+_1514711 0.05 ENSDART00000165641
v-akt murine thymoma viral oncogene homolog 1
chr19_+_2631565 0.05 ENSDART00000171487
family with sequence similarity 126, member A
chr21_-_43171249 0.04 ENSDART00000021037
ENSDART00000148630
heat shock protein 4a
chr7_+_50109239 0.04 ENSDART00000021605
si:dkey-6l15.1
chr15_+_28119284 0.04 ENSDART00000188366
unc-119 homolog a (C. elegans)
chr25_+_21054065 0.04 ENSDART00000148472
cholinergic receptor, muscarinic 2b
chr8_+_1433647 0.04 ENSDART00000160797
ephrin-A5b
chr19_-_25519310 0.04 ENSDART00000089882
si:dkey-202e17.1
chr8_+_37111643 0.04 ENSDART00000061336
renin
chr4_-_4387012 0.04 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr22_-_3595439 0.03 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr4_-_965267 0.03 ENSDART00000093289
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr8_+_36948256 0.03 ENSDART00000140410
IQ motif and Sec7 domain 2b
chr2_-_53925308 0.03 ENSDART00000190705

chr19_+_7595924 0.03 ENSDART00000140083
S100 calcium binding protein S
chr1_+_27153859 0.03 ENSDART00000180184
basonuclin 2
chr25_+_18587338 0.03 ENSDART00000180287
MET proto-oncogene, receptor tyrosine kinase
chr13_+_713941 0.02 ENSDART00000109737
cytochrome c oxidase assembly homolog 15 (yeast)
chr1_+_59328030 0.02 ENSDART00000172464

chr1_+_58067815 0.02 ENSDART00000156678
si:ch211-114l13.4
chr7_-_51793333 0.02 ENSDART00000180654

chr8_-_11146687 0.02 ENSDART00000189626
ankyrin repeat and SOCS box containing 13b
chr12_-_26423439 0.02 ENSDART00000113978
synaptopodin 2-like b
chr6_+_27339962 0.02 ENSDART00000193726
kelch-like family member 30
chr25_+_19008497 0.02 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr5_+_19479200 0.02 ENSDART00000137703
aldehyde dehydrogenase 3 family, member B2
chr4_-_77300601 0.02 ENSDART00000163015
ENSDART00000174015
solute carrier organic anion transporter family, member 1F2
chr1_+_58260886 0.02 ENSDART00000110453
si:dkey-222h21.8
chr6_-_42111937 0.02 ENSDART00000181772
glutamate receptor, metabotropic 2a
chr11_+_24819624 0.02 ENSDART00000155514
lysine (K)-specific demethylase 5Ba
chr4_+_12031958 0.02 ENSDART00000044154
troponin T2c, cardiac
chr19_-_3193912 0.01 ENSDART00000133159
si:ch211-133n4.6
chr3_-_33494163 0.01 ENSDART00000020342
small G protein signaling modulator 3
chr20_+_19793620 0.01 ENSDART00000136317
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr10_+_36354863 0.01 ENSDART00000159675
odorant receptor, family C, subfamily 104, member 1
chr14_-_27121854 0.01 ENSDART00000173119
protocadherin 11
chr1_-_22726233 0.01 ENSDART00000140920
prominin 1 b
chr23_+_216012 0.01 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr2_+_32016516 0.01 ENSDART00000135040
MYC proto-oncogene, bHLH transcription factor b
chr7_+_13988075 0.00 ENSDART00000186812
furin (paired basic amino acid cleaving enzyme) a

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 1.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.6 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.4 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.1 0.3 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.8 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.4 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.3 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.8 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.2 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 2.0 GO:0048599 oocyte development(GO:0048599)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.3 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.4 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.5 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0005991 trehalose metabolic process(GO:0005991)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.5 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.1 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.6 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0005689 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.0 0.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0009374 biotin binding(GO:0009374)
0.2 0.8 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.5 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.5 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.1 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.6 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.4 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression