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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr1h4

Z-value: 0.40

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Transcription factors associated with nr1h4

Gene Symbol Gene ID Gene Info
ENSDARG00000057741 nuclear receptor subfamily 1, group H, member 4
ENSDARG00000113600 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr1h4dr11_v1_chr18_+_15644559_15644559-0.822.6e-05Click!

Activity profile of nr1h4 motif

Sorted Z-values of nr1h4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_20693724 1.39 ENSDART00000141368
si:ch211-240b21.2
chr17_-_25395395 1.14 ENSDART00000170233
family with sequence similarity 167, member B
chr10_-_27197044 0.84 ENSDART00000137928
autism susceptibility candidate 2a
chr3_-_18030938 0.71 ENSDART00000013540
si:ch73-141c7.1
chr16_+_54263921 0.71 ENSDART00000002856
dopamine receptor D2 like
chr13_-_7766758 0.70 ENSDART00000171831
H2A histone family, member Y2
chr2_+_49644803 0.70 ENSDART00000160342
si:ch211-209f23.7
chr2_+_49799470 0.69 ENSDART00000146325
si:ch211-190k17.19
chr11_-_22372072 0.66 ENSDART00000065996
transmembrane protein 183A
chr19_+_32166702 0.66 ENSDART00000021798
fatty acid binding protein 11a
chr5_+_25072894 0.66 ENSDART00000012268
mitochondrial ribosomal protein L41
chr23_+_42810055 0.65 ENSDART00000186647
myosin, light chain 9a, regulatory
chr1_-_17650223 0.65 ENSDART00000043484
si:dkey-256e7.5
chr4_-_16545085 0.63 ENSDART00000033188
B-cell translocation gene 1, anti-proliferative
chr5_+_4366431 0.63 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr20_+_54685143 0.62 ENSDART00000162535
p21 protein (Cdc42/Rac)-activated kinase 7
chr8_-_48675775 0.62 ENSDART00000060785
Pim proto-oncogene, serine/threonine kinase, related 183
chr7_+_34688527 0.61 ENSDART00000108473
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr25_+_245018 0.60 ENSDART00000155344
zgc:92481
chr9_+_2499627 0.55 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr12_-_30841679 0.53 ENSDART00000105594
crystallin, gamma MX
chr15_-_15910226 0.53 ENSDART00000154219
synergin, gamma
chr11_+_5842632 0.53 ENSDART00000111374
ENSDART00000158599
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr8_-_48675411 0.52 ENSDART00000165081
Pim proto-oncogene, serine/threonine kinase, related 183
chr25_+_5012791 0.51 ENSDART00000156970
si:ch73-265h17.5
chr3_-_34027178 0.50 ENSDART00000170201
ENSDART00000151408
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 14-1
chr23_-_22598002 0.47 ENSDART00000146966
si:ch211-28e16.5
chr17_+_35431724 0.47 ENSDART00000190293

chr2_-_40191603 0.47 ENSDART00000180691
si:ch211-122l24.6
chr15_+_6652396 0.47 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr21_-_12036134 0.46 ENSDART00000031658
tubulin polyglutamylase complex subunit 2
chr20_-_4738101 0.45 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
poly(A) polymerase alpha
chr1_-_44704261 0.44 ENSDART00000133210
si:dkey-28b4.8
chr6_+_9398074 0.43 ENSDART00000151772
kalirin RhoGEF kinase b
chr25_-_16969922 0.43 ENSDART00000111158
tp53-induced glycolysis and apoptosis regulator a
chr7_+_528593 0.43 ENSDART00000091955
neurexin 2b
chr23_+_7471072 0.41 ENSDART00000135551
si:ch211-200e2.1
chr11_-_14924138 0.39 ENSDART00000168348
si:dkey-6d5.1
chr5_+_13385837 0.38 ENSDART00000191190
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr4_-_18455480 0.38 ENSDART00000150221
SCO2 cytochrome c oxidase assembly protein
chr22_+_10645088 0.36 ENSDART00000142265
Ras association (RalGDS/AF-6) domain family 1
chr2_+_371759 0.35 ENSDART00000153788
si:dkey-33c14.7
chr21_-_5879897 0.33 ENSDART00000184034
ribosomal protein L35
chr7_-_52531252 0.33 ENSDART00000174369
transcription factor 12
chr19_-_18855513 0.33 ENSDART00000162708
palmitoyl-protein thioesterase 2
chr1_-_21538329 0.33 ENSDART00000182798
ENSDART00000193518
ENSDART00000183873
ENSDART00000183376
WD repeat domain 19
chr21_-_14811058 0.32 ENSDART00000143100
phosphohistidine phosphatase 1
chr4_-_5597167 0.32 ENSDART00000132431
vascular endothelial growth factor Ab
chr22_+_34663328 0.32 ENSDART00000183912
si:ch73-304f21.1
chr3_-_52661242 0.31 ENSDART00000138018
zgc:113210
chr12_+_695619 0.31 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr21_+_44112914 0.30 ENSDART00000062836
fibroblast growth factor 1b
chr7_+_39399747 0.30 ENSDART00000147037
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr17_+_996509 0.29 ENSDART00000158830
cytochrome P450, family 1, subfamily C, polypeptide 2
chr16_+_53203370 0.29 ENSDART00000154669
si:ch211-269k10.2
chr18_+_22302635 0.29 ENSDART00000141051
capping protein regulator and myosin 1 linker 2
chr18_+_31056645 0.29 ENSDART00000159316
mevalonate (diphospho) decarboxylase a
chr2_-_6051836 0.28 ENSDART00000092479
si:ch211-284b7.3
chr25_-_24046870 0.28 ENSDART00000047569
insulin-like growth factor 2b
chr23_+_4253957 0.28 ENSDART00000008761
ADP-ribosylation factor-like 6 interacting protein 5b
chr5_-_38777852 0.28 ENSDART00000131603
si:dkey-58f10.4
chr11_+_41540862 0.28 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr5_+_54400971 0.28 ENSDART00000169695
B-box and SPRY domain containing
chr7_+_29153018 0.27 ENSDART00000138065
transmembrane protein with metallophosphoesterase domain
chr16_-_4769877 0.27 ENSDART00000149421
ENSDART00000054078
replication protein A2
chr10_+_28428222 0.27 ENSDART00000135003
si:ch211-222e20.4
chr1_-_9130136 0.27 ENSDART00000113013
partner and localizer of BRCA2
chr9_-_28616436 0.27 ENSDART00000136985
si:ch73-7i4.2
chr17_-_15149192 0.26 ENSDART00000180511
ENSDART00000103405
GTP cyclohydrolase 1
chr8_-_36469117 0.26 ENSDART00000111240
major histocompatibility complex class II DAB gene
chr19_-_18855717 0.26 ENSDART00000158192
palmitoyl-protein thioesterase 2
chr1_-_44940830 0.26 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr7_+_11197940 0.25 ENSDART00000081346
cell migration inducing protein, hyaluronan binding
chr23_+_28128453 0.25 ENSDART00000182618
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr1_+_58353661 0.25 ENSDART00000140074
si:dkey-222h21.2
chr17_+_5768608 0.24 ENSDART00000157039
retinitis pigmentosa 1-like 1a
chr8_-_29822527 0.23 ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr16_-_50157187 0.23 ENSDART00000155162
NIMA-related kinase 10
chr24_-_25184553 0.23 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_45942431 0.22 ENSDART00000060955
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr22_+_28888781 0.22 ENSDART00000145629
Pim proto-oncogene, serine/threonine kinase, related 98
chr10_+_20070178 0.22 ENSDART00000027612
ENSDART00000145264
ENSDART00000172713
exportin 7
chr3_+_31953145 0.22 ENSDART00000148861
potassium voltage-gated channel, Shaw-related subfamily, member 3a
chr5_+_69716458 0.22 ENSDART00000159594
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr13_+_35746440 0.22 ENSDART00000187859
G protein-coupled receptor 75
chr10_-_20696518 0.21 ENSDART00000064581
Kv channel interacting protein 3b, calsenilin
chr6_+_9677420 0.20 ENSDART00000064995
small ubiquitin-like modifier 1
chr21_-_20733615 0.20 ENSDART00000145544
si:ch211-22d5.2
chr22_+_7486867 0.20 ENSDART00000034586
zgc:112302
chr2_+_42072689 0.19 ENSDART00000134203
valosin containing protein (p97)/p47 complex interacting protein 1
chr24_+_28448387 0.19 ENSDART00000154077
ENSDART00000018037
Rho GTPase activating protein 29a
chr12_-_25201576 0.18 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr3_+_4346854 0.18 ENSDART00000004273
si:dkey-73p2.3
chr13_-_23665580 0.18 ENSDART00000144282
mitogen-activated protein kinase kinase kinase 21
chr11_+_21910752 0.18 ENSDART00000114288
forkhead box P4
chr16_+_5184402 0.17 ENSDART00000156685
SOGA family member 3a
chr6_-_40312091 0.17 ENSDART00000154878
collagen, type VII, alpha 1
chr11_-_6974022 0.17 ENSDART00000172851
si:ch211-43f4.1
chr7_-_16237861 0.17 ENSDART00000173647
bloodthirsty-related gene family, member 7
chr3_-_58582663 0.17 ENSDART00000180055

chr5_+_65946222 0.17 ENSDART00000190969
ENSDART00000161578
myomaker, myoblast fusion factor
chr16_+_5901835 0.16 ENSDART00000060519
unc-51 like kinase 4
chr25_+_23591990 0.16 ENSDART00000151938
ENSDART00000089199
carnitine palmitoyltransferase 1Ab (liver)
chr20_-_19864131 0.16 ENSDART00000057819
protein tyrosine kinase 2 beta, b
chr18_+_3338228 0.16 ENSDART00000161520
glycerophosphodiester phosphodiesterase domain containing 4a
chr18_-_41754020 0.16 ENSDART00000077898
G protein-coupled receptor kinase 7b
chr19_+_30990815 0.15 ENSDART00000134645
syncoilin, intermediate filament protein
chr18_+_19990412 0.15 ENSDART00000155054
ENSDART00000090310
protein inhibitor of activated STAT, 1b
chr24_-_21689146 0.14 ENSDART00000105917
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr16_-_50181206 0.14 ENSDART00000148478
lens intrinsic membrane protein 2.5
chr15_-_462783 0.14 ENSDART00000161049
Danio rerio uncharacterized LOC100002960 (LOC100002960), mRNA.
chr16_-_13281380 0.13 ENSDART00000103882
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr9_+_46644633 0.13 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr22_-_17474583 0.13 ENSDART00000148027
si:ch211-197g15.8
chr8_-_13013123 0.13 ENSDART00000147802
DENN/MADD domain containing 2Da
chr15_+_44472356 0.13 ENSDART00000155763
ENSDART00000028011
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr23_+_35684756 0.13 ENSDART00000132320
premelanosome protein b
chr23_+_43954809 0.12 ENSDART00000164080
corin, serine peptidase
chr7_-_41338923 0.12 ENSDART00000099138
neutrophil cytosolic factor 2
chr3_+_32142382 0.12 ENSDART00000133035
synaptotagmin Va
chr6_+_27418541 0.12 ENSDART00000187410
ciliary rootlet coiled-coil, rootletin family member 2
chr12_+_34119439 0.11 ENSDART00000032821
cytohesin 1b
chr6_-_1514767 0.11 ENSDART00000067586
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr11_+_12175162 0.11 ENSDART00000125446
si:ch211-156l18.7
chr14_-_34771371 0.11 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr5_+_1079423 0.11 ENSDART00000172231
si:zfos-128g4.2
chr1_+_44941031 0.11 ENSDART00000141145
si:dkey-9i23.16
chr11_+_11200550 0.11 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr25_+_12494079 0.10 ENSDART00000163508
microtubule-associated protein 1 light chain 3 beta
chr11_-_17713987 0.10 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr14_-_34276574 0.10 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr13_+_29238850 0.10 ENSDART00000026000
myoferlin like
chr19_-_23369282 0.10 ENSDART00000147824
Pim proto-oncogene, serine/threonine kinase, related 90
chr20_-_37522569 0.10 ENSDART00000177011
ENSDART00000058502
human immunodeficiency virus type I enhancer binding protein 2a
chr21_+_29179887 0.10 ENSDART00000161941
si:ch211-57b15.1
chr14_+_22297257 0.09 ENSDART00000113676
ATPase phospholipid transporting 10B
chr21_-_22547496 0.09 ENSDART00000166835
ENSDART00000089030
myosin VB
chr15_+_37331585 0.09 ENSDART00000170715
zgc:171592
chr8_+_10305400 0.09 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr22_-_17474781 0.09 ENSDART00000186817
si:ch211-197g15.8
chr8_+_8735285 0.08 ENSDART00000165655
ELK1, member of ETS oncogene family
chr24_-_36337395 0.08 ENSDART00000154402
si:ch211-40k21.9
chr15_-_31000275 0.08 ENSDART00000132493
ENSDART00000100183
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 6
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 5
chr15_-_923981 0.08 ENSDART00000155285
si:dkey-77f5.14
chr21_+_27370671 0.08 ENSDART00000009234
ENSDART00000142071
RNA binding motif protein 14a
chr17_+_20173882 0.08 ENSDART00000155379
si:ch211-248a14.8
chr22_-_11136625 0.08 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr4_+_70013627 0.08 ENSDART00000180432
si:dkey-190j3.4
chr14_-_3174570 0.08 ENSDART00000163585
colony stimulating factor 1 receptor, a
chr15_-_14552101 0.07 ENSDART00000171169
numb homolog (Drosophila)-like
chr6_-_609880 0.07 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr16_-_13730152 0.07 ENSDART00000138772
tweety family member 1
chr5_+_1219187 0.07 ENSDART00000129490
expressed sequence BC139872
chr15_-_19705707 0.07 ENSDART00000047643
synaptotagmin-like 2b
chr13_-_37200120 0.07 ENSDART00000135001
si:dkeyp-77c8.3
chr23_-_45504991 0.07 ENSDART00000148761
collagen type XXIV alpha 1
chr4_+_20812900 0.06 ENSDART00000005847
neuron navigator 3
chr20_+_7243879 0.06 ENSDART00000122298
barttin CLCNK-type chloride channel accessory beta subunit
chr9_-_48184823 0.06 ENSDART00000180264
kelch-like family member 23
chr19_+_30990129 0.06 ENSDART00000052169
ENSDART00000193376
syncoilin, intermediate filament protein
chr7_+_36539124 0.06 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr21_-_32082130 0.06 ENSDART00000003978
ENSDART00000182050
methionine adenosyltransferase II, beta
chr2_+_42112503 0.06 ENSDART00000136022
corticotropin releasing hormone a
chr3_-_19899914 0.06 ENSDART00000134969
Rho family GTPase 2
chr11_+_24340166 0.06 ENSDART00000188719
RNA binding motif protein 39a
chr23_-_42810664 0.05 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr20_+_9828769 0.05 ENSDART00000160480
ENSDART00000053844
ENSDART00000080691
syntaxin binding protein 6 (amisyn), like
chr4_+_1530287 0.05 ENSDART00000067446
solute carrier family 38, member 4
chr1_+_127250 0.05 ENSDART00000003463
coagulation factor VIIi
chr5_-_50748081 0.05 ENSDART00000113985
multiple C2 domains, transmembrane 1a
chr12_-_4370585 0.05 ENSDART00000129502
si:ch211-173d10.4
chr2_-_37862380 0.05 ENSDART00000186005
si:ch211-284o19.8
chr5_+_28830388 0.05 ENSDART00000149150
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr16_-_20312146 0.04 ENSDART00000134980
si:dkeyp-86h10.3
chr8_+_53311965 0.04 ENSDART00000130104
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr22_-_11137268 0.04 ENSDART00000178882
ATPase H+ transporting accessory protein 2
chr17_-_465285 0.04 ENSDART00000168718
cholinergic receptor, muscarinic 5a
chr23_-_21515182 0.04 ENSDART00000142000
ring finger protein 207b
chr2_-_52020049 0.04 ENSDART00000128198
ENSDART00000135331
sodium channel, voltage gated, type XII, alpha a
chr13_-_37108310 0.04 ENSDART00000163845
spectrin repeat containing, nuclear envelope 2b
chr14_-_2318590 0.04 ENSDART00000192735
protocadherin 2 alpha b 8
chr21_-_45186431 0.03 ENSDART00000193449
si:ch73-269m14.2
chr10_+_22012389 0.03 ENSDART00000035188
Kv channel interacting protein 1 b
chr19_-_1929310 0.03 ENSDART00000144113
si:ch211-149a19.3
chr18_-_16791331 0.03 ENSDART00000148222
adenosine monophosphate deaminase 3b
chr17_+_14711765 0.02 ENSDART00000012889
connexin 28.6
chr1_-_22512063 0.02 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr5_-_69571572 0.02 ENSDART00000145966
mitogen-activated protein kinase-activated protein kinase 5
chr14_+_904850 0.02 ENSDART00000161847
si:ch73-208h1.1
chr16_-_17175731 0.02 ENSDART00000183057
opsin 9
chr7_-_1918971 0.01 ENSDART00000181759

chr15_-_34322915 0.01 ENSDART00000190543
ENSDART00000019651
ENSDART00000193601
diacylglycerol kinase, beta
chr7_+_53755054 0.01 ENSDART00000181629
neogenin 1a
chr12_+_13405445 0.01 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr5_+_16496273 0.00 ENSDART00000168969
ENSDART00000147442
5-hydroxytryptamine (serotonin) receptor 7c
chr21_+_40092301 0.00 ENSDART00000145150
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr7_-_8014186 0.00 ENSDART00000190012
si:cabz01030277.1
chr3_+_59117136 0.00 ENSDART00000182745
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

Network of associatons between targets according to the STRING database.

First level regulatory network of nr1h4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.4 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.1 0.5 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.3 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.2 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 0.7 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.7 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.3 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.1 GO:2000562 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.3 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.3 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.7 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0048038 quinone binding(GO:0048038)
0.0 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling